Zfpm2 (zinc finger protein, multitype 2) - Rat Genome Database

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Pathways
Gene: Zfpm2 (zinc finger protein, multitype 2) Rattus norvegicus
Analyze
Symbol: Zfpm2
Name: zinc finger protein, multitype 2
RGD ID: 1306021
Description: Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; transcription coactivator activity; and transcription corepressor activity. Predicted to be involved in several processes, including cardiac chamber morphogenesis; positive regulation of cardiac muscle cell proliferation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including circulatory system development; in utero embryonic development; and lung development. Predicted to be located in cytoplasm and male germ cell nucleus. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in 46,XY sex reversal 9; congenital diaphragmatic hernia; myelodysplastic syndrome; and tetralogy of Fallot. Orthologous to human ZFPM2 (zinc finger protein, FOG family member 2); INTERACTS WITH 6-propyl-2-thiouracil; acetamide; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FOG-2; zinc finger protein ZFPM2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8773,563,732 - 74,001,041 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl773,563,732 - 74,001,041 (+)EnsemblGRCr8
mRatBN7.2771,678,658 - 72,116,209 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl771,678,880 - 72,116,205 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx773,563,335 - 73,995,149 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0775,765,841 - 76,197,677 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0775,633,940 - 76,065,769 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0779,471,277 - 79,964,405 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl779,638,046 - 79,964,405 (+)Ensemblrn6Rnor6.0
Rnor_5.0779,491,886 - 79,976,680 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4776,210,472 - 76,654,443 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera768,728,223 - 69,158,299 (+)NCBICelera
RGSC_v3.1776,324,843 - 76,675,169 (+)NCBI
Cytogenetic Map7q31NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. AML1-FOG2 fusion protein in myelodysplasia. Chan EM, etal., Blood. 2005 Jun 1;105(11):4523-6. Epub 2005 Feb 10.
2. Retinoid X receptor alpha represses GATA-4-mediated transcription via a retinoid-dependent interaction with the cardiac-enriched repressor FOG-2. Clabby ML, etal., J Biol Chem 2003 Feb 21;278(8):5760-7.
3. FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Garnatz AS, etal., Dev Biol. 2014 Nov 1;395(1):50-61. doi: 10.1016/j.ydbio.2014.08.030. Epub 2014 Sep 6.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor. Klarin D, etal., Circ Cardiovasc Genet. 2017 Apr;10(2):e001643. doi: 10.1161/CIRCGENETICS.116.001643.
6. Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension. Kumarasamy S, etal., Nat Commun. 2015 Feb 17;6:6252. doi: 10.1038/ncomms7252.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Mutations of ZFPM2/FOG2 gene in sporadic cases of tetralogy of Fallot. Pizzuti A, etal., Hum Mutat. 2003 Nov;22(5):372-7.
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Comprehensive gene review and curation RGD comprehensive gene curation
14. The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex. Roche AE, etal., J Mol Cell Cardiol. 2008 Feb;44(2):352-60. Epub 2007 Nov 12.
15. Increased FOG-2 in failing myocardium disrupts thyroid hormone-dependent SERCA2 gene transcription. Rouf R, etal., Circ Res. 2008 Aug 29;103(5):493-501. doi: 10.1161/CIRCRESAHA.108.181487. Epub 2008 Jul 25.
16. CpG island shore methylation of ZFPM2 is identified in tetralogy of fallot samples. Sheng W, etal., Pediatr Res. 2016 Jul;80(1):151-8. doi: 10.1038/pr.2016.42. Epub 2016 Mar 9.
17. A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2. Svensson EC, etal., Nat Genet. 2000 Jul;25(3):353-6. doi: 10.1038/77146.
Additional References at PubMed
PMID:9927675   PMID:10225993   PMID:10438528   PMID:10892744   PMID:12213678   PMID:12606418   PMID:15220332   PMID:15766748   PMID:16103912   PMID:17445768   PMID:19301398   PMID:20206639  
PMID:20705609   PMID:20807224   PMID:22267003  


Genomics

Comparative Map Data
Zfpm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8773,563,732 - 74,001,041 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl773,563,732 - 74,001,041 (+)EnsemblGRCr8
mRatBN7.2771,678,658 - 72,116,209 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl771,678,880 - 72,116,205 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx773,563,335 - 73,995,149 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0775,765,841 - 76,197,677 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0775,633,940 - 76,065,769 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0779,471,277 - 79,964,405 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl779,638,046 - 79,964,405 (+)Ensemblrn6Rnor6.0
Rnor_5.0779,491,886 - 79,976,680 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4776,210,472 - 76,654,443 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera768,728,223 - 69,158,299 (+)NCBICelera
RGSC_v3.1776,324,843 - 76,675,169 (+)NCBI
Cytogenetic Map7q31NCBI
ZFPM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388105,318,438 - 105,804,539 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8104,590,733 - 105,804,539 (+)Ensemblhg38GRCh38
GRCh378106,330,666 - 106,816,767 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368106,400,323 - 106,885,943 (+)NCBIBuild 36Build 36hg18NCBI36
Build 348106,400,322 - 106,885,941NCBI
Celera8102,518,281 - 103,003,726 (+)NCBICelera
Cytogenetic Map8q23.1NCBI
HuRef8101,532,803 - 102,138,045 (+)NCBIHuRef
CHM1_18106,371,762 - 106,857,264 (+)NCBICHM1_1
T2T-CHM13v2.08106,445,857 - 106,932,108 (+)NCBIT2T-CHM13v2.0
Zfpm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391540,518,438 - 40,967,988 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1540,518,431 - 40,967,988 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381540,655,042 - 41,104,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1540,655,035 - 41,104,592 (+)Ensemblmm10GRCm38
MGSCv371540,486,588 - 40,936,138 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361540,485,116 - 40,934,666 (+)NCBIMGSCv36mm8
Celera1541,140,194 - 41,582,164 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1515.74NCBI
Zfpm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541728,920,210 - 29,269,271 (+)Ensembl
ChiLan1.0NW_00495541728,931,428 - 29,268,778 (+)NCBIChiLan1.0ChiLan1.0
ZFPM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27122,596,111 - 123,154,098 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1898,118,921 - 98,676,812 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08101,872,850 - 102,430,622 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18104,193,343 - 104,577,698 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8104,023,062 - 104,576,688 (+)EnsemblpanPan2panpan1.1
ZFPM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1136,435,368 - 6,796,903 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl136,336,794 - 6,796,322 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha136,442,921 - 6,803,153 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0136,588,050 - 7,045,717 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl136,587,518 - 7,044,757 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1136,451,443 - 6,811,875 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0136,571,226 - 6,931,950 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0136,646,836 - 7,007,257 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Zfpm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530331,006,795 - 31,431,557 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647038,432,897 - 38,857,662 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647038,432,894 - 38,857,656 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZFPM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl431,606,773 - 32,094,287 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1431,607,968 - 31,996,226 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2434,232,973 - 34,242,599 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2434,441,657 - 34,641,574 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZFPM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18100,138,867 - 100,620,355 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603939,958,226 - 40,438,731 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zfpm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476321,388,244 - 21,707,953 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476321,388,060 - 21,708,969 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Zfpm2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11214,333,917 - 214,343,557 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Zfpm2
3102 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:199
Count of miRNA genes:114
Interacting mature miRNAs:150
Transcripts:ENSRNOT00000029419
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74511390390113903Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)771103011106126789Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)75170064396700643Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
1298525Cm1Cardiac mass QTL 12.7heart mass (VT:0007028)heart wet weight (CMO:0000069)756625161101625161Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)771621154114982716Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)773618702118618702Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73984590284845902Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73299870277998702Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73617876481178764Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)755498584105834451Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)763889858108889858Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74847504993475049Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73617876481178764Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)773557047118557047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
10450862Kidm55Kidney mass QTL 554.9kidney mass (VT:0002707)kidney weight (CMO:0000081)772725037117725037Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)762963207107963207Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)763889858108889858Rat
10450856Livw4Liver weight QTL 43.8liver mass (VT:0003402)liver weight (CMO:0000092)772725037117725037Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
2303582Gluco53Glucose level QTL 533blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)74860308793603087Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)771621154119349044Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
D7Rat22  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.4776,615,342 - 76,615,501UniSTSRGSC3.4
RGSC_v3.4776,615,341 - 76,615,501RGDRGSC3.4
Celera769,120,095 - 69,120,250UniSTS
RGSC_v3.1776,636,071 - 76,636,231RGD
RH 3.4 Map7620.3RGD
RH 3.4 Map7620.3UniSTS
RH 2.0 Map7478.6RGD
SHRSP x BN Map745.53RGD
FHH x ACI Map736.75RGD
Cytogenetic Map7q22-q31UniSTS
D7Rat142  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2771,788,963 - 71,789,091 (+)MAPPERmRatBN7.2
Rnor_6.0779,629,118 - 79,629,245NCBIRnor6.0
Rnor_5.0779,648,702 - 79,648,829UniSTSRnor5.0
RGSC_v3.4776,323,357 - 76,323,874RGDRGSC3.4
RGSC_v3.4776,323,578 - 76,323,705UniSTSRGSC3.4
Celera768,837,793 - 68,837,920UniSTS
RGSC_v3.1776,344,308 - 76,344,435RGD
RH 3.4 Map7621.8UniSTS
RH 3.4 Map7621.8RGD
SHRSP x BN Map745.53UniSTS
SHRSP x BN Map745.53RGD
Cytogenetic Map7q22-q31UniSTS
D7Got234  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2771,906,963 - 71,907,149 (+)MAPPERmRatBN7.2
Rnor_6.0779,745,450 - 79,745,635NCBIRnor6.0
Rnor_5.0779,765,034 - 79,765,219UniSTSRnor5.0
RGSC_v3.4776,442,431 - 76,442,616UniSTSRGSC3.4
Celera768,949,245 - 68,949,428UniSTS
Cytogenetic Map7q22-q31UniSTS
AW532229  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2771,806,271 - 71,806,429 (+)MAPPERmRatBN7.2
Rnor_6.0779,646,431 - 79,646,589NCBIRnor6.0
Rnor_5.0779,666,015 - 79,666,173UniSTSRnor5.0
RGSC_v3.4776,340,888 - 76,341,045UniSTSRGSC3.4
Celera768,855,075 - 68,855,232UniSTS
RH 3.4 Map7621.5UniSTS
Cytogenetic Map7q22-q31UniSTS
PMC303372P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2772,115,403 - 72,115,888 (+)MAPPERmRatBN7.2
Rnor_6.0779,963,604 - 79,964,088NCBIRnor6.0
Rnor_5.0779,975,879 - 79,976,363UniSTSRnor5.0
RGSC_v3.4776,653,642 - 76,654,126UniSTSRGSC3.4
Celera769,157,498 - 69,157,982UniSTS
Cytogenetic Map7q22-q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 145 91 90 59 28 59 6 272 128 11 124 61 92 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000029419   ⟹   ENSRNOP00000035072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl773,563,732 - 74,001,041 (+)Ensembl
mRatBN7.2 Ensembl771,678,880 - 72,116,205 (+)Ensembl
Rnor_6.0 Ensembl779,638,046 - 79,964,405 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000121714   ⟹   ENSRNOP00000104529
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl773,564,045 - 74,001,041 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000128336   ⟹   ENSRNOP00000099393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl773,845,360 - 74,001,041 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000171636   ⟹   ENSRNOP00000103913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl773,563,734 - 74,001,036 (+)Ensembl
RefSeq Acc Id: NM_001130501   ⟹   NP_001123973
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8773,563,732 - 74,001,041 (+)NCBI
mRatBN7.2771,678,880 - 72,116,205 (+)NCBI
Rnor_6.0779,471,277 - 79,964,405 (+)NCBI
Rnor_5.0779,491,886 - 79,976,680 (+)NCBI
RGSC_v3.4776,210,472 - 76,654,443 (+)RGD
Celera768,728,223 - 69,158,299 (+)RGD
Sequence:
RefSeq Acc Id: XM_039079162   ⟹   XP_038935090
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8773,564,151 - 74,001,035 (+)NCBI
mRatBN7.2771,678,658 - 72,116,209 (+)NCBI
RefSeq Acc Id: XM_039079163   ⟹   XP_038935091
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8773,845,276 - 74,001,035 (+)NCBI
mRatBN7.2771,959,241 - 72,116,209 (+)NCBI
RefSeq Acc Id: NP_001123973   ⟸   NM_001130501
- UniProtKB: D4A0R1 (UniProtKB/TrEMBL),   A6HR90 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000035072   ⟸   ENSRNOT00000029419
RefSeq Acc Id: XP_038935090   ⟸   XM_039079162
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038935091   ⟸   XM_039079163
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000103913   ⟸   ENSRNOT00000171636
Ensembl Acc Id: ENSRNOP00000099393   ⟸   ENSRNOT00000128336
Ensembl Acc Id: ENSRNOP00000104529   ⟸   ENSRNOT00000121714
Protein Domains
C2H2-type   CCHC FOG-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A0R1-F1-model_v2 AlphaFold D4A0R1 1-1090 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306021 AgrOrtholog
BioCyc Gene G2FUF-33537 BioCyc
Ensembl Genes ENSRNOG00000004109 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000029419 ENTREZGENE
  ENSRNOT00000029419.8 UniProtKB/TrEMBL
  ENSRNOT00000121714.1 UniProtKB/TrEMBL
  ENSRNOT00000128336 ENTREZGENE
  ENSRNOT00000128336.1 UniProtKB/TrEMBL
  ENSRNOT00000171636 ENTREZGENE
  ENSRNOT00000171636.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro FOG UniProtKB/TrEMBL
  ZF_CCHC_FOG UniProtKB/TrEMBL
  ZFPM1/2_PR UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
KEGG Report rno:314930 UniProtKB/TrEMBL
NCBI Gene 314930 ENTREZGENE
PANTHER PTHR12958 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN ZFPM2 UniProtKB/TrEMBL
Pfam CCHC_ZFPM2 UniProtKB/TrEMBL
  FOG1-like_PR UniProtKB/TrEMBL
PhenoGen Zfpm2 PhenoGen
PROSITE ZF_CCHC_FOG UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004109 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0ABK0L4P1_RAT UniProtKB/TrEMBL
  A0ABK0LEL3_RAT UniProtKB/TrEMBL
  A0ABK0LRI2_RAT UniProtKB/TrEMBL
  A6HR90 ENTREZGENE, UniProtKB/TrEMBL
  D4A0R1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Zfpm2  zinc finger protein, multitype 2   Zfpm2_predicted  zinc finger protein, multitype 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Zfpm2_predicted  zinc finger protein, multitype 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED