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Gene: Olig3 (oligodendrocyte transcription factor 3) Rattus norvegicus

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Symbol:

Olig3

Name:

oligodendrocyte transcription factor 3

RGD ID:

1305997

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and E-box binding activity. Predicted to be involved in axon development; positive regulation of transcription by RNA polymerase II; and sensory organ development. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II; spinal cord motor neuron cell fate specification; and spinal cord motor neuron migration. Predicted to be active in nucleus. Orthologous to human OLIG3 (oligodendrocyte transcription factor 3); INTERACTS WITH bisphenol A; glyphosate; 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ortholog).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC293012; oligodendrocyte transcription factor 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	15,900,881 - 15,902,953 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	15,900,736 - 15,902,274 (+)	Ensembl				GRCr8
mRatBN7.2	1	14,081,259 - 14,083,336 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	14,081,328 - 14,082,149 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	13,840,322 - 13,842,404 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	19,842,266 - 19,844,350 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	14,061,398 - 14,063,463 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	14,797,766 - 14,799,835 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	14,797,766 - 14,799,835 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	16,343,568 - 16,345,637 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	14,568,462 - 14,570,533 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	12,527,890 - 12,529,961 (+)	NCBI		Celera
RGSC_v3.1	1	14,568,354 - 14,570,595 (+)	NCBI
Cytogenetic Map	1	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dimethylhydrazine (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,4,4'-trichlorobiphenyl (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

5-fluorouracil (ISO)

abacavir (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

CHIR 99021 (ISO)

choline (ISO)

dabigatran (ISO)

dorsomorphin (ISO)

entinostat (ISO)

ethanol (ISO)

ethylene glycol (ISO)

folic acid (ISO)

fonofos (ISO)

glyphosate (EXP)

isotretinoin (ISO)

L-methionine (ISO)

lipopolysaccharide (ISO)

N(4)-hydroxycytidine (ISO)

nilotinib (ISO)

panobinostat (ISO)

parathion (ISO)

PCB138 (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenytoin (ISO)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

terbufos (ISO)

thalidomide (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon development (IBA)

DNA-templated transcription (IEA)

negative regulation of transcription by RNA polymerase II (ISO)

neuron fate commitment (IEA)

positive regulation of transcription by RNA polymerase II (IBA)

regulation of gene expression (ISO)

sensory organ development (IBA)

spinal cord motor neuron cell fate specification (ISO)

spinal cord motor neuron differentiation (ISO)

spinal cord motor neuron migration (ISO)

Cellular Component

nucleus (IBA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

E-box binding (IBA)

protein binding (ISO)

protein dimerization activity (IEA)

sequence-specific double-stranded DNA binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15674731	PMID:15769945

Genomics

Comparative Map Data

Olig3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	15,900,881 - 15,902,953 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	15,900,736 - 15,902,274 (+)	Ensembl				GRCr8
mRatBN7.2	1	14,081,259 - 14,083,336 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	14,081,328 - 14,082,149 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	13,840,322 - 13,842,404 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	19,842,266 - 19,844,350 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	14,061,398 - 14,063,463 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	14,797,766 - 14,799,835 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	14,797,766 - 14,799,835 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	16,343,568 - 16,345,637 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	14,568,462 - 14,570,533 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	12,527,890 - 12,529,961 (+)	NCBI		Celera
RGSC_v3.1	1	14,568,354 - 14,570,595 (+)	NCBI
Cytogenetic Map	1	p12	NCBI

OLIG3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	137,492,199 - 137,494,394 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	137,492,199 - 137,494,394 (-)	Ensembl			hg38	GRCh38
GRCh37	6	137,813,336 - 137,815,531 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	137,855,029 - 137,857,224 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	137,855,028 - 137,857,224	NCBI
Celera	6	138,553,474 - 138,555,669 (-)	NCBI		Celera
Cytogenetic Map	6	q23.3	NCBI
HuRef	6	135,375,512 - 135,377,708 (-)	NCBI		HuRef
CHM1_1	6	138,075,547 - 138,077,743 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	138,680,645 - 138,682,841 (-)	NCBI		T2T-CHM13v2.0

Olig3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	19,232,287 - 19,234,352 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	19,232,281 - 19,234,352 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	19,356,539 - 19,358,604 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	19,356,533 - 19,358,604 (+)	Ensembl			mm10	GRCm38
MGSCv37	10	19,076,345 - 19,078,410 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	19,045,953 - 19,048,020 (+)	NCBI		MGSCv36	mm8
Celera	10	19,255,439 - 19,257,539 (+)	NCBI		Celera
Cytogenetic Map	10	A3	NCBI
cM Map	10	8.33	NCBI

Olig3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955436	21,929,086 - 21,929,904 (+)	Ensembl
ChiLan1.0	NW_004955436	21,929,086 - 21,929,904 (+)	NCBI	ChiLan1.0	ChiLan1.0

OLIG3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	157,451,637 - 157,453,843 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	155,350,945 - 155,353,151 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	135,245,422 - 135,248,355 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	139,332,779 - 139,334,975 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	139,333,938 - 139,334,756 (-)	Ensembl			panPan2	panpan1.1

OLIG3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	29,919,043 - 29,921,713 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	29,920,190 - 29,921,008 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	30,802,543 - 30,803,421 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	30,088,185 - 30,089,063 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	1	29,966,232 - 29,967,110 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	29,850,573 - 29,851,451 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	30,156,470 - 30,157,348 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Olig3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	125,014,379 - 125,016,661 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936560	4,794,747 - 4,795,565 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936560	4,793,595 - 4,795,781 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

OLIG3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	26,800,671 - 26,801,489 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	26,800,671 - 26,801,489 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	30,151,022 - 30,151,840 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

OLIG3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	35,925,356 - 35,926,211 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	35,925,373 - 35,926,194 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666040	8,118,234 - 8,120,420 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Olig3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624886	330,068 - 330,886 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624886	329,887 - 331,938 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Olig3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	217,216,333 - 217,218,395 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Olig3
13 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	218
Count of miRNA genes:	147
Interacting mature miRNAs:	168
Transcripts:	ENSRNOT00000016048
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313090	Bmd69	Bone mineral density QTL 69	4.4	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	5293229	34184556	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	7746118	52746118	Rat
4889451	Eae29	Experimental allergic encephalomyelitis QTL 29	5.51		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	1	7746121	52746121	Rat
70179	Xhs2	X-ray hypersensitivity QTL 2	3.2		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	1	1	43965634	Rat
1354647	Despr8	Despair related QTL 8		0.0000341	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	1	26564886	Rat
1558642	Prcr2	Prostate cancer resistance QTL 2	4.3		prostate integrity trait (VT:0010571)	area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)	1	10379492	55379492	Rat
7421626	Bp360	Blood pressure QTL 360		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	6941022	51941022	Rat
2313070	Bss52	Bone structure and strength QTL 52	4.4	0.0001	body length (VT:0001256)	body length (CMO:0000013)	1	5293229	34184556	Rat
1357401	Bw43	Body weight QTL 43	3.75		body mass (VT:0001259)	body weight (CMO:0000012)	1	6909353	51909353	Rat
1600360	Mcs16	Mammary carcinoma susceptibility QTL 16	2.4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	1	26564886	Rat
5684998	Bss101	Bone structure and strength QTL 101	3.6		tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	1	6909353	51909353	Rat
5684999	Bss102	Bone structure and strength QTL 102	5.5	7e-07	tibia strength trait (VT:1000284)	tibia stiffness (CMO:0001735)	1	6909353	51909353	Rat
2302038	Pia31	Pristane induced arthritis QTL 31	5.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	1	12820494	57820494	Rat
2317755	Glom22	Glomerulus QTL 22	3.8		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	1	34184556	Rat
1300170	Rf6	Renal function QTL 6	3.14		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	1	1	28483164	Rat
631508	Sald1	Serum aldosterone level QTL 1	3.7		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	1	11684464	56684464	Rat
2313053	Bss51	Bone structure and strength QTL 51	3.8	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	5293229	34184556	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
7	8	16	100	48	47	18	26	18	5	109	62	81	15	37	29	2	2

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473994	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000016048 ⟹ ENSRNOP00000016048

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	14,797,766 - 14,799,835 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000108658 ⟹ ENSRNOP00000087458

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	15,900,736 - 15,902,274 (+)	Ensembl
mRatBN7.2 Ensembl	1	14,081,328 - 14,082,149 (+)	Ensembl

RefSeq Acc Id:

NM_001106269 ⟹ NP_001099739

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	15,900,881 - 15,902,953 (+)	NCBI
mRatBN7.2	1	14,081,259 - 14,083,336 (+)	NCBI
Rnor_6.0	1	14,797,766 - 14,799,835 (+)	NCBI
Rnor_5.0	1	16,343,568 - 16,345,637 (+)	NCBI
RGSC_v3.4	1	14,568,462 - 14,570,533 (+)	RGD
Celera	1	12,527,890 - 12,529,961 (+)	RGD

Sequence:

show sequence

AATTCGAGATTATCTTTAATTTCCCGCCTAAAGCTTCCTCAACCATAAGGCCGCATCTCCTGTA
ATAAAATGAATTCTGATTCGAGCTCTGTCTCCAGCAGAGCGTCATCTCCGGACATGGATGAGAT
GTACCTAAGAGACCACCACCACCGCCACCACCACCACCATCAGGAGAGCCGTCTTAACTCGGTC
TCATCCACACAGGGCGACATGGTGCAAAAGATGCCCGGGGAGAGCCTCTCACGGGCAGGCGCCA
AAGCTGCAGGAGAAAGCAGCAAGTACAAAATCAAGAAGCAGCTGTCGGAGCAGGATCTTCAGCA
GTTGCGGCTGAAGATCAACGGACGCGAACGCAAGAGGATGCACGACCTGAACCTCGCCATGGAT
GGTCTGCGCGAGGTCATGCCCTATGCGCACGGGCCCTCGGTGCGCAAGCTCTCCAAGATCGCCA
CTCTGCTTCTAGCCAGAAACTACATCCTCATGCTCACCAGCTCCCTGGAGGAGATGAAGAGGTT
GGTTGGCGAGATCTACGGTGGACACCACTCGGCCTTCCACTGTGGGACTGTGGGGCATTCGGCT
GGCCACCCGGCACACGCGGCCAACGCCGTGCACCCGGTGCACCCTATCCTGGGCGGCGCGCTCT
CCTCTGGCAATGCCTCGTCCCCGCTGTCTGCCGCCTCCCTGCCGACCATAGGCACCATCCGACC
TCCCCACTCACTGCTCAAGGCGCCCTCCACGCCGCCCGCACTACAGCTGGGCAGCGGCTTCCAG
CACTGGGCGGGGCTGCCCTGTCCCTGCACCATCTGCCAGATGCCACCGCCGCCGCACCTGTCCG
CTCTCTCCACCGCCAACATGGCCCGGCTTTCGGCCGAATCCAAGGACTTGCTCAAGTGAGCCAC
GGGCTGGCCCGGCCGGGAGGAGGAAGGGAGAGCTGAGGCAGGGGTCGCAGTGCCGGGCCAGGAG
GGAAGGGGAGACTGCTCGACCTGCGGGAGGGTGGGCGCGCGGCCCTGAGGCCTCACTAGCGCCC
TAGAGATCCAGATTCCTCTTGACGCACTCCAGCGGGGCTTACCAAAACCAAACTGGAATACCTA
GGTGTTAGCGAAGGGGACTGGAACCCGACGTCCTGATTTGCATGCATGCTTCTTTCCCTCATGC
AGCGCCAGTATTTCTCACTGCCATATGCTCTTGTCAACACTGCATTTGTTGTTTAAAGATGGGA
TCGGTGGAGTTAGAAACTTGCAAAGGAACTTTGGAGCTGACTGTTTCTGGCTGTGTTCTTATCT
CGGAGGAAAGACGTCCTTTTGTGCAAAGGAAATGTAAATATTTCATCGAGCTAGATGCAGTTAT
GATTGCCTCTGCCCTTATAAGACAATGGGGAGAGAAGGGGAGAGAGAGAGAGAGAGAGAGAGAG
AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGATTGATTCAGAGTCCAAGTTTCTAATCTAA
GCCCAGGGCATGAACCTCTTATGTGGGTTTTCCTTTCCACGCAATATAGGTCAAAAGAATGCAT
GCACGCTCCTAAATGAATCTTGTCTAAACATATTGTGCGGGCTATAGTGCCATTTCCTTGTAAC
AAGGATTTATTAGAGAATTCTCCAAAGTACTCCATATATCTGTCTGTGGTTGTATAAAAAGGGG
CCAGAGTGCAAAGATTCACACTCAGTGAACATGTGATTCTTTCCCCAAGCTCATGTCTGTCCCT
GATCCTCAAACTTCATTCCAACTTTACGGCTGTTCCAAAGGCCCGAAGTCACAAAACTGGGCCT
CTTCTAAAAGCTCATCCCACCCCCTTGCCAAGTTATTCTGCATGCGGGGTTGGCTCTGTCTGTT
ATCCCTCAGCTCTGAAAACCCTCTGTGTTTGGGGGGGGGGGGCTGCCACTTTTATTTTCCTGAA
CATTTGCTTGAAATATTTTGTTAGGGCCTCAAAGACAATACCTGTCTTTATTTTTTATATATTC
TTGATAAGTATGATATATTTATTAATAACCAGTGTTTCTGGATGAGATTTCAAATAAAAAAGAA
CCTTTAAATCCGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001099739	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL93782	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000087458
	ENSRNOP00000087458.1

RefSeq Acc Id:

NP_001099739 ⟸ NM_001106269

- UniProtKB:

D4A572 (UniProtKB/TrEMBL), A6JPB0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNSDSSSVSSRASSPDMDEMYLRDHHHRHHHHHQESRLNSVSSTQGDMVQKMPGESLSRAGAKA
AGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKIATL
LLARNYILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANAVHPVHPILGGALSS
GNASSPLSAASLPTIGTIRPPHSLLKAPSTPPALQLGSGFQHWAGLPCPCTICQMPPPPHLSAL
STANMARLSAESKDLLK

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Ensembl Acc Id:

ENSRNOP00000016048 ⟸ ENSRNOT00000016048

Ensembl Acc Id:

ENSRNOP00000087458 ⟸ ENSRNOT00000108658

Protein Domains

bHLH

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A572-F1-model_v2	AlphaFold	D4A572	1-273	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305997	AgrOrtholog
BioCyc Gene	G2FUF-62234	BioCyc
Ensembl Genes	ENSRNOG00000012057	Ensembl
	ENSRNOG00000064127	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000108658	ENTREZGENE
	ENSRNOT00000108658.2	UniProtKB/TrEMBL
Gene3D-CATH	4.10.280.10	UniProtKB/TrEMBL
InterPro	bHLH_transcription_factors	UniProtKB/TrEMBL
	HLH_DNA-bd	UniProtKB/TrEMBL
	HLH_DNA-bd_sf	UniProtKB/TrEMBL
	Olig3	UniProtKB/TrEMBL
KEGG Report	rno:293012	UniProtKB/TrEMBL
NCBI Gene	293012	ENTREZGENE
PANTHER	BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED	UniProtKB/TrEMBL
	PTHR19290:SF96	UniProtKB/TrEMBL
Pfam	HLH	UniProtKB/TrEMBL
PhenoGen	Olig3	PhenoGen
PROSITE	HLH	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000012057	RatGTEx
	ENSRNOG00000064127	RatGTEx
SMART	HLH	UniProtKB/TrEMBL
Superfamily-SCOP	HLH_basic	UniProtKB/TrEMBL
UniProt	A6JPB0	ENTREZGENE, UniProtKB/TrEMBL
	D4A572	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Olig3	oligodendrocyte transcription factor 3	Olig3_predicted	oligodendrocyte transcription factor 3 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Olig3_predicted	oligodendrocyte transcription factor 3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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