OLIG3 (oligodendrocyte transcription factor 3)

Gene: OLIG3 (oligodendrocyte transcription factor 3) Chlorocebus sabaeus

Analyze

Symbol:

OLIG3

Name:

oligodendrocyte transcription factor 3

RGD ID:

18713034

Description:

ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); E-box binding (inferred); protein dimerization activity (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); regulation of gene expression (ortholog); spinal cord motor neuron cell fate specification (ortholog); ASSOCIATED WITH Familial Behcet-Like Autoinflammatory Syndrome (ortholog); Nontuberculous Mycobacterium Infections (ortholog); FOUND IN nucleus (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	35,925,356 - 35,926,211 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	35,925,373 - 35,926,194 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	8,118,234 - 8,120,420 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Familial Behcet-Like Autoinflammatory Syndrome (ISO)

Nontuberculous Mycobacterium Infections (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon development (IEA)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA)

regulation of gene expression (IEA,ISO)

sensory organ development (IEA)

spinal cord motor neuron cell fate specification (IEA,ISO)

spinal cord motor neuron differentiation (IEA,ISO)

spinal cord motor neuron migration (IEA,ISO)

Cellular Component

nucleus (IEA)

Molecular Function

DNA-binding transcription factor activity, RNA polymerase II-specific (IEA)

E-box binding (IEA)

protein binding (ISO)

protein dimerization activity (IEA)

sequence-specific double-stranded DNA binding (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

OLIG3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	35,925,356 - 35,926,211 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	35,925,373 - 35,926,194 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	8,118,234 - 8,120,420 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

OLIG3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	137,492,199 - 137,494,394 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	137,492,199 - 137,494,394 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	137,813,336 - 137,815,531 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	137,855,029 - 137,857,224 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	137,855,028 - 137,857,224	NCBI
Celera	6	138,553,474 - 138,555,669 (-)	NCBI		Celera
Cytogenetic Map	6	q23.3	NCBI
HuRef	6	135,375,512 - 135,377,708 (-)	NCBI		HuRef
CHM1_1	6	138,075,547 - 138,077,743 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	138,680,645 - 138,682,841 (-)	NCBI		T2T-CHM13v2.0

Olig3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	19,232,287 - 19,234,352 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	19,232,281 - 19,234,352 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	19,356,539 - 19,358,604 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	19,356,533 - 19,358,604 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	19,076,345 - 19,078,410 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	19,045,953 - 19,048,020 (+)	NCBI		MGSCv36	mm8
Celera	10	19,255,439 - 19,257,539 (+)	NCBI		Celera
Cytogenetic Map	10	A3	NCBI
cM Map	10	8.33	NCBI

Olig3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	15,900,881 - 15,902,953 (+)	NCBI		GRCr8
mRatBN7.2	1	14,081,259 - 14,083,336 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	14,081,328 - 14,082,149 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	13,840,322 - 13,842,404 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	19,842,266 - 19,844,350 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	14,061,398 - 14,063,463 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	14,797,766 - 14,799,835 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	14,797,766 - 14,799,835 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	16,343,568 - 16,345,637 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	14,568,462 - 14,570,533 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	14,568,354 - 14,570,595 (+)	NCBI
Celera	1	12,527,890 - 12,529,961 (+)	NCBI		Celera
Cytogenetic Map	1	p12	NCBI

Olig3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955436	21,929,086 - 21,929,904 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955436	21,929,086 - 21,929,904 (+)	NCBI	ChiLan1.0	ChiLan1.0

OLIG3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	157,451,637 - 157,453,843 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	155,350,945 - 155,353,151 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	135,245,422 - 135,248,355 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	139,332,779 - 139,334,975 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	139,333,938 - 139,334,756 (-)	Ensembl	panpan1.1		panPan2

OLIG3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	29,919,043 - 29,921,713 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	29,920,190 - 29,921,008 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	30,802,543 - 30,803,421 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	30,088,185 - 30,089,063 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	1	29,966,232 - 29,967,110 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	29,850,573 - 29,851,451 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	30,156,470 - 30,157,348 (-)	NCBI		UU_Cfam_GSD_1.0

Olig3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	125,014,379 - 125,016,661 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936560	4,794,747 - 4,795,565 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936560	4,793,595 - 4,795,781 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

OLIG3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	26,800,671 - 26,801,489 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	26,800,671 - 26,801,489 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	30,151,022 - 30,151,840 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Olig3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624886	330,068 - 330,886 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624886	329,887 - 331,938 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	hemolymphoid system
High
Medium
Low	11
Below cutoff	6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008006884	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCSAT00000018350 ⟹ ENSCSAP00000017810

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	13	35,925,373 - 35,926,194 (+)	Ensembl

RefSeq Acc Id:

XM_008006884 ⟹ XP_008005075

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	13	35,925,356 - 35,926,211 (+)	NCBI
Vero_WHO_p1.0	NW_023666040	8,118,234 - 8,120,420 (+)	NCBI

Sequence:

show sequence

GCATCCCCTCTAATAAAATGAATTCTGATTCGAGCTCTGTCTCCAGCAGAGCTTCATCTCCGGA
CATGGACGAGATGTACCTGAGGGACCACCACCACCGCCACCACCACCACCACCAGGAGAGCCGT
CTCAACTCGGTCTCGTCCACGCAGGGCGATATGATGCAGAAGATGTCCGGGGAAAGCCTCTCGC
GGGCTGGCGCCAAGGCCGCGGGAGAAAGCAGCAAGTACAAAATCAAGAAGCAGCTGTCGGAGCA
GGACCTACAGCAGTTGCGGCTGAAGATCAACGGACGCGAACGCAAGCGGATGCACGACCTGAAC
CTCGCCATGGACGGGCTGCGCGAAGTCATGCCCTACGCACACGGGCCCTCGGTGCGCAAGCTCT
CCAAGATCGCCACCCTCCTGCTTGCCAGAAACTACATTCTCATGCTCACCAGCTCCCTGGAGGA
GATGAAGAGGCTGGTTGGAGAGATCTATGGTGGCCACCACTCGGCCTTTCACTGCGGGACCGTG
GGCCACTCGGCCGGCCACCCCGCGCACGCGGCCAACGCAGTGCACCCTGTGCACCCCATCCTGG
GCTGCGCGCTCTCATCCGGCAACGCCTCGTCACCGCTGTCCGCCGCCTCACTTCCCTCCATCGG
CACCATCCGGCCTCCCCACTCGCTGCTCAAGGCGCCCTCCACGCCGCCCGCGCTGCAGCTGGGC
AGCGGCTTCCAGCACTGGGCTGGTCTGCCTTGCCCCTGCACCATCTGCCAGATGCCGCCGCCTC
CGCACCTGTCCGCTCTCTCCACCGCCAACATGGCCCGGCTGTCGGCCGAGTCCAAGGACTTGCT
CAAGTGAGCAGCGGGCGGGCCCGG

hide sequence

Protein Sequences


Protein RefSeqs	XP_008005075	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000017810.1

RefSeq Acc Id:	XP_008005075 ⟸ XM_008006884
- UniProtKB:	A0A0D9SAC1 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCSAP00000017810 ⟸ ENSCSAT00000018350

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000000185	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000018350.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.280.10	UniProtKB/TrEMBL
InterPro	bHLH_dom	UniProtKB/TrEMBL
	HLH_DNA-bd_sf	UniProtKB/TrEMBL
	Olig3	UniProtKB/TrEMBL
KEGG Report	csab:103240301	UniProtKB/TrEMBL
NCBI Gene	OLIG3	ENTREZGENE
PANTHER	BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED	UniProtKB/TrEMBL
	PTHR19290:SF96	UniProtKB/TrEMBL
Pfam	HLH	UniProtKB/TrEMBL
PROSITE	BHLH	UniProtKB/TrEMBL
SMART	HLH	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47459	UniProtKB/TrEMBL
UniProt	A0A0D9SAC1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar