Cers1 (ceramide synthase 1) - Rat Genome Database

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Gene: Cers1 (ceramide synthase 1) Rattus norvegicus
Analyze
Symbol: Cers1 (Ensembl: Gdf1)
Name: ceramide synthase 1 (Ensembl:growth differentiation factor 1)
RGD ID: 1305974
Description: Predicted to enable sphingosine N-acyltransferase activity. Predicted to be involved in several processes, including cellular response to UV-A; cellular response to dithiothreitol; and cellular response to mycotoxin. Predicted to act upstream of or within brain development. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 8. Orthologous to human CERS1 (ceramide synthase 1); INTERACTS WITH acrylamide; bisphenol A; furan.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: LAG1 homolog, ceramide synthase 1; LAG1 homolog, ceramide synthase 1 (S. cerevisiae); LAG1 longevity assurance homolog 1; LAG1 longevity assurance homolog 1 (S. cerevisiae); Lass1; LOC290658; longevity assurance homolog 1; longevity assurance homolog 1 (S. cerevisiae); longevity assurance-like protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,131,271 - 19,146,480 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1619,131,276 - 19,146,480 (-)EnsemblGRCr8
mRatBN7.21619,097,309 - 19,112,519 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1619,104,466 - 19,112,519 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1619,137,150 - 19,152,310 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,269,455 - 20,284,820 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,190,111 - 19,205,271 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,845,580 - 20,860,789 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,845,576 - 20,860,789 (-)Ensemblrn6Rnor6.0
Rnor_5.01620,698,122 - 20,712,564 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41619,580,807 - 19,596,415 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1619,287,577 - 19,302,834 (-)NCBICelera
RGSC_v3.11619,588,709 - 19,596,385 (-)NCBI
Cytogenetic Map16p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Downregulation of ceramide synthase 1 promotes oral cancer through endoplasmic reticulum stress. Chen W, etal., Int J Oral Sci. 2021 Mar 22;13(1):10. doi: 10.1038/s41368-021-00118-4.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. CerS1-Derived C18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance. Turpin-Nolan SM, etal., Cell Rep. 2019 Jan 2;26(1):1-10.e7. doi: 10.1016/j.celrep.2018.12.031.
8. Fetal asphyxia induces acute and persisting changes in the ceramide metabolism in rat brain. Vlassaks E, etal., J Lipid Res. 2013 Jul;54(7):1825-33. doi: 10.1194/jlr.M034447. Epub 2013 Apr 26.
9. A deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation. Zhao L, etal., PLoS Genet. 2011 May;7(5):e1002063. doi: 10.1371/journal.pgen.1002063. Epub 2011 May 19.
Additional References at PubMed
PMID:12105227   PMID:12477932   PMID:12869556   PMID:15248193   PMID:15823095   PMID:16951403   PMID:17364820   PMID:17548428   PMID:17699106   PMID:17977534   PMID:18541923   PMID:19800881  
PMID:24782409   PMID:25771159   PMID:26620563  


Genomics

Comparative Map Data
Cers1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81619,131,271 - 19,146,480 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1619,131,276 - 19,146,480 (-)EnsemblGRCr8
mRatBN7.21619,097,309 - 19,112,519 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1619,104,466 - 19,112,519 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1619,137,150 - 19,152,310 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,269,455 - 20,284,820 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,190,111 - 19,205,271 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,845,580 - 20,860,789 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,845,576 - 20,860,789 (-)Ensemblrn6Rnor6.0
Rnor_5.01620,698,122 - 20,712,564 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41619,580,807 - 19,596,415 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1619,287,577 - 19,302,834 (-)NCBICelera
RGSC_v3.11619,588,709 - 19,596,385 (-)NCBI
Cytogenetic Map16p14NCBI
CERS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,868,545 - 18,896,982 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,868,545 - 18,896,727 (-)Ensemblhg38GRCh38
GRCh371918,979,354 - 19,007,791 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,842,117 - 18,867,953 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341918,849,726 - 18,867,953NCBI
Celera1918,884,162 - 18,911,776 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,543,712 - 18,571,613 (-)NCBIHuRef
CHM1_11918,979,170 - 19,006,647 (-)NCBICHM1_1
T2T-CHM13v2.01919,004,162 - 19,032,606 (-)NCBIT2T-CHM13v2.0
Cers1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,768,425 - 70,784,238 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,768,425 - 70,784,242 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38870,315,775 - 70,331,588 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,315,775 - 70,331,592 (+)Ensemblmm10GRCm38
MGSCv37872,839,674 - 72,855,487 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36873,244,776 - 73,260,576 (+)NCBIMGSCv36mm8
Celera872,872,244 - 72,888,065 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Cers1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,788,653 - 2,796,370 (+)Ensembl
ChiLan1.0NW_0049555242,788,672 - 2,798,068 (+)NCBIChiLan1.0ChiLan1.0
CERS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,731,595 - 23,758,078 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,737,809 - 22,764,286 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01918,308,265 - 18,334,892 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1 Ensembl1919,317,173 - 19,342,487 (-)EnsemblpanPan2panpan1.1
CERS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,216,568 - 44,231,820 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,131,420 - 44,140,737 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02044,702,943 - 44,712,260 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,701,496 - 44,718,307 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12043,940,230 - 43,949,547 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,350,440 - 44,359,760 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02044,625,909 - 44,635,225 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cers1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118202,893,836 - 202,918,153 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,442,991 - 2,467,184 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,442,978 - 2,467,184 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CERS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl258,951,727 - 58,974,670 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1258,951,463 - 58,972,692 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2258,750,506 - 58,769,955 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CERS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,331,021 - 17,351,542 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660741,972,193 - 1,994,871 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cers1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,941,393 - 1,949,760 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249081,937,007 - 1,949,780 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cers1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11312,573,036 - 12,581,617 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cers1
54 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:43
Interacting mature miRNAs:44
Transcripts:ENSRNOT00000027275
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549842Bp248Blood pressure QTL 2480.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1638712345387123Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133425095Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139568015Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16423421253708481Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161574800625801629Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16474422249744222Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16126734272Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126734272Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16435482249354822Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)1638712345387123Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16423421249757901Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)161627818427244292Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139568015Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338679049757901Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338679026128267Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126734272Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161773081872536785Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683908652786090Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)161590580260905802Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16330168348301683Rat

Markers in Region
AI385651  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21619,097,350 - 19,097,450 (+)MAPPERmRatBN7.2
Rnor_6.01620,845,622 - 20,845,721NCBIRnor6.0
Rnor_5.01620,698,164 - 20,698,263UniSTSRnor5.0
RGSC_v3.41619,580,849 - 19,580,948UniSTSRGSC3.4
Celera1619,287,619 - 19,287,718UniSTS
Cytogenetic Map16p14UniSTS
RH139099  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21619,097,348 - 19,097,496 (+)MAPPERmRatBN7.2
Rnor_6.01620,845,620 - 20,845,767NCBIRnor6.0
Rnor_5.01620,698,162 - 20,698,309UniSTSRnor5.0
RGSC_v3.41619,580,847 - 19,580,994UniSTSRGSC3.4
Celera1619,287,617 - 19,287,764UniSTS
RH 3.4 Map16233.4UniSTS
Cytogenetic Map16p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 1 24 124 30 26 14 68 14 6 181 114 11 111 42 59 12 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000027275   ⟹   ENSRNOP00000027275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1619,104,466 - 19,112,519 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092417   ⟹   ENSRNOP00000075903
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1619,131,276 - 19,146,480 (-)Ensembl
Rnor_6.0 Ensembl1620,845,576 - 20,860,789 (-)Ensembl
RefSeq Acc Id: NM_001044230   ⟹   NP_001037695
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81619,131,271 - 19,146,480 (-)NCBI
mRatBN7.21619,097,309 - 19,112,519 (-)NCBI
Rnor_6.01620,845,580 - 20,860,789 (-)NCBI
Rnor_5.01620,698,122 - 20,712,564 (-)NCBI
RGSC_v3.41619,580,807 - 19,596,415 (-)RGD
Celera1619,287,577 - 19,302,834 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001037695 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABF19583 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000075903
  ENSRNOP00000075903.3
RefSeq Acc Id: NP_001037695   ⟸   NM_001044230
- UniProtKB: Q1HL14 (UniProtKB/TrEMBL),   F7F646 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075903   ⟸   ENSRNOT00000092417
Ensembl Acc Id: ENSRNOP00000027275   ⟸   ENSRNOT00000027275
Protein Domains
TLC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q1HL14-F1-model_v2 AlphaFold Q1HL14 1-350 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700035
Promoter ID:EPDNEW_R10559
Type:initiation region
Name:Cers1_1
Description:ceramide synthase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01620,860,797 - 20,860,857EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305974 AgrOrtholog
BioCyc Gene G2FUF-11771 BioCyc
Ensembl Genes ENSRNOG00000062030 Ensembl
  ENSRNOG00000067124 Ensembl
  ENSRNOG00000070518 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000092417 ENTREZGENE
  ENSRNOT00000092417.3 UniProtKB/TrEMBL
Gene3D-CATH Cystine-knot cytokines UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  Lag1/Lac1-like UniProtKB/TrEMBL
  TGF-b_C UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/TrEMBL
  TGFb_CS UniProtKB/TrEMBL
  TLC-dom UniProtKB/TrEMBL
KEGG Report rno:290658 UniProtKB/TrEMBL
  rno:306351 UniProtKB/TrEMBL
NCBI Gene 290658 ENTREZGENE
PANTHER CERAMIDE SYNTHASE 1 UniProtKB/TrEMBL
  EMBRYONIC GROWTH_DIFFERENTIATION FACTOR 1 UniProtKB/TrEMBL
  LONGEVITY ASSURANCE FACTOR 1 LAG1 UniProtKB/TrEMBL
  TGF-BETA FAMILY UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/TrEMBL
  TRAM_LAG1_CLN8 UniProtKB/TrEMBL
PhenoGen Cers1 PhenoGen
PRINTS INHIBINA UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/TrEMBL
  TLC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000062030 RatGTEx
  ENSRNOG00000067124 RatGTEx
  ENSRNOG00000070518 RatGTEx
SMART TGFB UniProtKB/TrEMBL
  TLC UniProtKB/TrEMBL
Superfamily-SCOP Cystine-knot cytokines UniProtKB/TrEMBL
UniProt F7F646 ENTREZGENE
  Q1HL14 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Cers1  ceramide synthase 1  Lass1  LAG1 homolog, ceramide synthase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-19 Lass1  LAG1 homolog, ceramide synthase 1  Lass1  LAG1 homolog, ceramide synthase 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-17 Lass1  LAG1 homolog, ceramide synthase 1 (S. cerevisiae)  Lass1_predicted  longevity assurance homolog 1 (S. cerevisiae) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Lass1_predicted  longevity assurance homolog 1 (S. cerevisiae) (predicted)    LAG1 longevity assurance homolog 1 (S. cerevisiae) (predicted)  Name updated 1299863 APPROVED
2005-01-12 Lass1_predicted  LAG1 longevity assurance homolog 1 (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED