Arih2 (ariadne RBR E3 ubiquitin protein ligase 2) - Rat Genome Database

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Gene: Arih2 (ariadne RBR E3 ubiquitin protein ligase 2) Rattus norvegicus
Analyze
Symbol: Arih2
Name: ariadne RBR E3 ubiquitin protein ligase 2
RGD ID: 1305839
Description: Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including hematopoietic stem cell proliferation; positive regulation of protein targeting to mitochondrion; and protein polyubiquitination. Predicted to be located in nucleoplasm. Predicted to be part of Cul5-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human ARIH2 (ariadne RBR E3 ubiquitin protein ligase 2); INTERACTS WITH 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol; 4-tert-Octylphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ARI2; ariadne homolog 2; ariadne homolog 2 (Drosophila); E3 ubiquitin-protein ligase ARIH2; LOC316005; TRIAD1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,175,267 - 118,234,425 (-)NCBIGRCr8
mRatBN7.28109,296,738 - 109,355,909 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,296,738 - 109,355,852 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8114,914,976 - 114,973,753 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,114,311 - 113,173,088 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08110,956,949 - 111,015,728 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,387,004 - 117,446,085 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,387,010 - 117,446,019 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,731,507 - 116,790,857 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,647,000 - 113,705,922 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,667,741 - 113,725,377 (-)NCBI
Celera8108,592,510 - 108,651,513 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,6-dinitrotoluene  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
4-tert-Octylphenol  (EXP)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
carbamazepine  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dieldrin  (ISO)
diethylstilbestrol  (EXP)
disodium selenite  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
hydralazine  (ISO)
indometacin  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylphenidate  (ISO)
N(4)-hydroxycytidine  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
p-tert-Amylphenol  (EXP)
paracetamol  (ISO)
PCB138  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
resveratrol  (ISO)
silicon dioxide  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
tetraphene  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:10431818   PMID:16118314   PMID:19340006   PMID:24076655   PMID:24270810   PMID:30320922   PMID:30409224   PMID:34641746   PMID:36055408  


Genomics

Comparative Map Data
Arih2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,175,267 - 118,234,425 (-)NCBIGRCr8
mRatBN7.28109,296,738 - 109,355,909 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,296,738 - 109,355,852 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8114,914,976 - 114,973,753 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,114,311 - 113,173,088 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08110,956,949 - 111,015,728 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,387,004 - 117,446,085 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,387,010 - 117,446,019 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,731,507 - 116,790,857 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,647,000 - 113,705,922 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18113,667,741 - 113,725,377 (-)NCBI
Celera8108,592,510 - 108,651,513 (-)NCBICelera
Cytogenetic Map8q32NCBI
ARIH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38348,918,842 - 48,986,382 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl348,918,821 - 48,986,382 (+)EnsemblGRCh38hg38GRCh38
GRCh37348,956,275 - 49,023,815 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,931,285 - 48,997,978 (+)NCBINCBI36Build 36hg18NCBI36
Build 34348,935,201 - 48,997,973NCBI
Celera348,912,042 - 48,977,617 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef349,014,398 - 49,080,892 (+)NCBIHuRef
CHM1_1348,908,394 - 48,975,548 (+)NCBICHM1_1
T2T-CHM13v2.0348,947,848 - 49,014,431 (+)NCBIT2T-CHM13v2.0
Arih2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,480,141 - 108,531,917 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9108,480,141 - 108,526,585 (-)EnsemblGRCm39 Ensembl
GRCm389108,602,942 - 108,653,681 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,602,942 - 108,649,386 (-)EnsemblGRCm38mm10GRCm38
MGSCv379108,505,273 - 108,551,711 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369108,460,279 - 108,506,785 (-)NCBIMGSCv36mm8
Celera9108,214,330 - 108,260,897 (-)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.54NCBI
Arih2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955532933,749 - 1,008,619 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955532933,749 - 1,008,619 (+)NCBIChiLan1.0ChiLan1.0
ARIH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2248,898,436 - 48,964,393 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1348,903,201 - 48,969,161 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0348,844,161 - 48,910,183 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1349,926,429 - 49,991,929 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl349,926,453 - 49,991,924 (+)Ensemblpanpan1.1panPan2
ARIH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12040,178,560 - 40,230,870 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2040,179,168 - 40,230,880 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2040,097,300 - 40,148,650 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02040,536,542 - 40,588,556 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2040,534,709 - 40,588,543 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12039,902,999 - 39,954,471 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02040,306,725 - 40,358,037 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02040,586,423 - 40,638,435 (-)NCBIUU_Cfam_GSD_1.0
Arih2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560263,888,186 - 63,951,437 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936529648,675 - 713,675 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936529648,661 - 713,616 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARIH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,570,088 - 31,625,226 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,570,026 - 31,623,833 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,821,469 - 34,873,436 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103227609
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,319,039 - 10,398,244 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2210,328,154 - 10,385,184 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236666404,923 - 69,475 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arih2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247302,953,669 - 3,023,042 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247302,953,649 - 3,023,716 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arih2
217 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:923
Count of miRNA genes:313
Interacting mature miRNAs:416
Transcripts:ENSRNOT00000042577
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat

Markers in Region
RH140905  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,298,422 - 109,298,624 (+)MAPPERmRatBN7.2
Rnor_6.08117,388,689 - 117,388,890NCBIRnor6.0
Rnor_5.08116,733,192 - 116,733,393UniSTSRnor5.0
RGSC_v3.48113,648,685 - 113,648,886UniSTSRGSC3.4
Celera8108,594,195 - 108,594,396UniSTS
RH 3.4 Map81119.4UniSTS
Cytogenetic Map8q32UniSTS
RH127724  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,296,913 - 109,297,115 (+)MAPPERmRatBN7.2
Rnor_6.08117,387,180 - 117,387,381NCBIRnor6.0
Rnor_5.08116,731,683 - 116,731,884UniSTSRnor5.0
RGSC_v3.48113,647,176 - 113,647,377UniSTSRGSC3.4
Celera8108,592,686 - 108,592,887UniSTS
RH 3.4 Map81119.1UniSTS
Cytogenetic Map8q32UniSTS
AJ130975  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,298,578 - 109,298,711 (+)MAPPERmRatBN7.2
Rnor_6.08117,388,845 - 117,388,977NCBIRnor6.0
Rnor_5.08116,733,348 - 116,733,480UniSTSRnor5.0
RGSC_v3.48113,648,841 - 113,648,973UniSTSRGSC3.4
Celera8108,594,351 - 108,594,483UniSTS
Cytogenetic Map8q32UniSTS
AI234621  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,346,490 - 109,346,664 (+)MAPPERmRatBN7.2
Rnor_6.08117,436,751 - 117,436,924NCBIRnor6.0
Rnor_5.08116,781,589 - 116,781,762UniSTSRnor5.0
RGSC_v3.48113,696,654 - 113,696,827UniSTSRGSC3.4
Celera8108,642,245 - 108,642,418UniSTS
RH 3.4 Map81117.3UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000042577   ⟹   ENSRNOP00000050012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8109,296,738 - 109,355,852 (-)Ensembl
Rnor_6.0 Ensembl8117,387,010 - 117,446,019 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095184   ⟹   ENSRNOP00000085248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8109,296,738 - 109,355,852 (-)Ensembl
RefSeq Acc Id: NM_001012275   ⟹   NP_001012275
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,175,267 - 118,234,284 (-)NCBI
mRatBN7.28109,296,738 - 109,355,762 (-)NCBI
Rnor_6.08117,387,004 - 117,446,019 (-)NCBI
Rnor_5.08116,731,507 - 116,790,857 (-)NCBI
RGSC_v3.48113,647,000 - 113,705,922 (-)RGD
Celera8108,592,510 - 108,651,513 (-)RGD
Sequence:
RefSeq Acc Id: XM_006243785   ⟹   XP_006243847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,175,267 - 118,234,171 (-)NCBI
mRatBN7.28109,296,738 - 109,355,648 (-)NCBI
Rnor_6.08117,387,004 - 117,445,854 (-)NCBI
Rnor_5.08116,731,507 - 116,790,857 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006243787   ⟹   XP_006243849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,175,267 - 118,227,389 (-)NCBI
mRatBN7.28109,296,738 - 109,348,858 (-)NCBI
Rnor_6.08117,387,004 - 117,439,068 (-)NCBI
Rnor_5.08116,731,507 - 116,790,857 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766537   ⟹   XP_008764759
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,175,267 - 118,234,425 (-)NCBI
mRatBN7.28109,296,738 - 109,355,909 (-)NCBI
Rnor_6.08117,387,004 - 117,446,085 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039081600   ⟹   XP_038937528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,175,267 - 118,232,523 (-)NCBI
mRatBN7.28109,296,738 - 109,353,888 (-)NCBI
RefSeq Acc Id: XM_063265630   ⟹   XP_063121700
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,177,643 - 118,227,524 (-)NCBI
RefSeq Acc Id: NP_001012275   ⟸   NM_001012275
- UniProtKB: D3ZJB8 (UniProtKB/TrEMBL),   A6I373 (UniProtKB/TrEMBL),   A0A8I6A0Y1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243847   ⟸   XM_006243785
- Peptide Label: isoform X1
- UniProtKB: D3ZJB8 (UniProtKB/TrEMBL),   A6I373 (UniProtKB/TrEMBL),   A0A8I6A0Y1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243849   ⟸   XM_006243787
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A0Y1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008764759   ⟸   XM_008766537
- Peptide Label: isoform X1
- UniProtKB: D3ZJB8 (UniProtKB/TrEMBL),   A6I373 (UniProtKB/TrEMBL),   A0A8I6A0Y1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000050012   ⟸   ENSRNOT00000042577
RefSeq Acc Id: XP_038937528   ⟸   XM_039081600
- Peptide Label: isoform X1
- UniProtKB: D3ZJB8 (UniProtKB/TrEMBL),   A6I373 (UniProtKB/TrEMBL),   A0A8I6A0Y1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085248   ⟸   ENSRNOT00000095184
RefSeq Acc Id: XP_063121700   ⟸   XM_063265630
- Peptide Label: isoform X2
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZJB8-F1-model_v2 AlphaFold D3ZJB8 1-492 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305839 AgrOrtholog
BioCyc Gene G2FUF-29122 BioCyc
Ensembl Genes ENSRNOG00000031827 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000042577.5 UniProtKB/TrEMBL
  ENSRNOT00000095184.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1750 UniProtKB/TrEMBL
  2.20.25.20 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro Ariadne UniProtKB/TrEMBL
  BRcat_RBR_TRIAD1 UniProtKB/TrEMBL
  E3_UB_ligase_RBR UniProtKB/TrEMBL
  Rcat_RBR_TRIAD1 UniProtKB/TrEMBL
  TRIAD_supradom UniProtKB/TrEMBL
  Znf_C3HC4_RING-type UniProtKB/TrEMBL
  Znf_C6HC UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report rno:316005 UniProtKB/TrEMBL
NCBI Gene 316005 ENTREZGENE
PANTHER PTHR11685 UniProtKB/TrEMBL
  PTHR11685:SF210 UniProtKB/TrEMBL
Pfam Ariadne UniProtKB/TrEMBL
  IBR UniProtKB/TrEMBL
  IBR_1 UniProtKB/TrEMBL
  zf-C3HC4 UniProtKB/TrEMBL
PhenoGen Arih2 PhenoGen
PROSITE TRIAD UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031827 RatGTEx
SMART IBR UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A8I6A0Y1 ENTREZGENE, UniProtKB/TrEMBL
  A6I373 ENTREZGENE, UniProtKB/TrEMBL
  D3ZJB8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-11 Arih2  ariadne RBR E3 ubiquitin protein ligase 2  Arih2  ariadne homolog 2 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Arih2  ariadne homolog 2 (Drosophila)   Arih2_predicted  ariadne homolog 2 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Arih2_predicted  ariadne homolog 2 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED