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Gene: Eipr1 (EARP complex and GARP complex interacting protein 1) Rattus norvegicus

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Symbol:

Eipr1

Name:

EARP complex and GARP complex interacting protein 1

RGD ID:

1305817

Description:

Involved in endocytic recycling and regulation of insulin secretion. Predicted to be located in trans-Golgi network. Predicted to be part of EARP complex and GARP complex. Orthologous to human EIPR1 (EARP complex and GARP complex interacting protein 1); INTERACTS WITH 2,4,6-trinitrotoluene; 2,4-dinitrotoluene; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

EARP and GARP complex-interacting protein 1; LOC362721; Tssc1; tumor suppressing subtransferable candidate 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	51,116,827 - 51,230,453 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	51,116,747 - 51,230,452 (+)	Ensembl				GRCr8
mRatBN7.2	6	45,388,451 - 45,502,089 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	45,388,376 - 45,502,083 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	45,686,874 - 45,800,608 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	46,001,738 - 46,115,459 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	45,438,605 - 45,552,313 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	48,021,771 - 48,135,241 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	48,021,771 - 48,135,241 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	56,723,808 - 56,837,116 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	46,633,907 - 46,747,548 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	44,611,430 - 44,723,913 (+)	NCBI		Celera
RGSC_v3.1	6	46,637,032 - 46,750,674 (+)	NCBI
Cytogenetic Map	6	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

substance-related disorder (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,6-trinitrotoluene (EXP)

2,4-dinitrotoluene (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

5-fluorouracil (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

alpha-pinene (ISO)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbon nanotube (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

ethanol (ISO)

FR900359 (ISO)

gallic acid (ISO)

gentamycin (EXP)

glafenine (EXP)

ivermectin (ISO)

methapyrilene (ISO)

nitrates (ISO)

ozone (ISO)

paracetamol (EXP)

potassium chromate (ISO)

sodium arsenite (ISO)

tetrachloromethane (EXP)

thiram (ISO)

titanium dioxide (ISO)

Triptolide (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endocytic recycling (IMP)

positive regulation of endocytic recycling (IEA,ISO,ISS)

positive regulation of retrograde transport, endosome to Golgi (IEA,ISO,ISS)

protein ubiquitination (IBA)

regulation of insulin secretion (IMP)

regulation of transport (IEA)

Cellular Component

EARP complex (IEA,ISO,ISS)

GARP complex (IEA,ISO,ISS)

Golgi apparatus (IEA)

nucleolus (IEA,ISO)

nucleoplasm (IEA,ISO)

trans-Golgi network (IEA,ISO,ISS)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	A proposed clinical application of a model of CO2 laser radiation induced damage craters.	Canestri F, J Med Eng Technol. 1988 May-Jun;12(3):112-7. doi: 10.3109/03091908809030166.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles.	Topalidou I, etal., PLoS Genet. 2016 May 18;12(5):e1006074. doi: 10.1371/journal.pgen.1006074. eCollection 2016 May.

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:27440922

Genomics

Comparative Map Data

Eipr1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	51,116,827 - 51,230,453 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	51,116,747 - 51,230,452 (+)	Ensembl				GRCr8
mRatBN7.2	6	45,388,451 - 45,502,089 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	45,388,376 - 45,502,083 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	45,686,874 - 45,800,608 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	46,001,738 - 46,115,459 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	45,438,605 - 45,552,313 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	48,021,771 - 48,135,241 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	48,021,771 - 48,135,241 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	56,723,808 - 56,837,116 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	46,633,907 - 46,747,548 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	44,611,430 - 44,723,913 (+)	NCBI		Celera
RGSC_v3.1	6	46,637,032 - 46,750,674 (+)	NCBI
Cytogenetic Map	6	q16	NCBI

EIPR1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	3,188,970 - 3,377,818 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	3,188,925 - 3,377,852 (-)	Ensembl			hg38	GRCh38
GRCh37	2	3,192,741 - 3,381,589 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	3,171,750 - 3,360,605 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	2	4,731,025 - 4,919,881	NCBI
Celera	2	3,247,171 - 3,432,956 (-)	NCBI		Celera
Cytogenetic Map	2	p25.3	NCBI
HuRef	2	3,178,593 - 3,367,574 (-)	NCBI		HuRef
CHM1_1	2	3,121,970 - 3,311,040 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	3,210,031 - 3,399,939 (-)	NCBI		T2T-CHM13v2.0

Eipr1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	28,801,802 - 28,917,493 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	28,801,802 - 28,919,864 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	12	28,751,802 - 28,867,494 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	28,751,803 - 28,869,865 (+)	Ensembl			mm10	GRCm38
MGSCv37	12	29,436,693 - 29,552,356 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	12	29,338,134 - 29,453,674 (+)	NCBI		MGSCv36	mm8
Celera	12	30,245,320 - 30,361,761 (+)	NCBI		Celera
Cytogenetic Map	12	A2	NCBI
cM Map	12	11.26	NCBI

Eipr1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955487	3,865,640 - 3,959,801 (+)	Ensembl
ChiLan1.0	NW_004955487	3,865,469 - 3,959,750 (+)	NCBI	ChiLan1.0	ChiLan1.0

EIPR1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	123,136,687 - 123,313,358 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	123,140,664 - 123,317,335 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	3,210,030 - 3,386,505 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	3,138,744 - 3,310,042 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	3,137,864 - 3,310,042 (-)	Ensembl			panPan2	panpan1.1

EIPR1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	1,869,924 - 1,989,856 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	1,869,925 - 1,989,721 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	1,855,451 - 1,975,696 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	1,963,755 - 2,083,932 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	1,963,760 - 2,083,954 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	1,849,037 - 1,968,969 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	1,870,032 - 1,989,977 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	1,871,410 - 1,991,806 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Eipr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	46,746,086 - 46,858,010 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936532	1,499,774 - 1,613,031 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936532	1,501,132 - 1,613,043 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EIPR1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	131,360,883 - 131,435,579 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	131,360,898 - 131,435,619 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	140,570,772 - 140,645,454 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EIPR1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	104,316,524 - 104,488,776 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	104,316,306 - 104,488,873 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666045	7,751,408 - 7,929,600 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Eipr1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624846	5,251,340 - 5,347,201 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624846	5,251,344 - 5,347,062 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Eipr1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	7	42,276,265 - 42,319,286 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Eipr1
1027 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	75
Count of miRNA genes:	56
Interacting mature miRNAs:	69
Transcripts:	ENSRNOT00000060185
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9590290	Uminl2	Urine mineral level QTL 2	3.96	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	6	44510974	89510974	Rat
8693632	Alc27	Alcohol consumption QTL 27	2.2	0.791	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	6	40052411	56848866	Rat
634318	Bw118	Body weight QTL 118	3.55		abdominal fat pad mass (VT:1000711)	abdominal fat pad weight (CMO:0000088)	6	39028659	63457441	Rat
634307	Bp141	Blood pressure QTL 141	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	40957564	85957564	Rat
10401812	Kidm54	Kidney mass QTL 54			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	20097635	65097635	Rat
1331743	Uae28	Urinary albumin excretion QTL 28	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	45153786	90153786	Rat
8552910	Pigfal5	Plasma insulin-like growth factor 1 level QTL 5	4.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	22653889	67653889	Rat
10401800	Kidm49	Kidney mass QTL 49			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	20097635	65097635	Rat
1331779	Rf38	Renal function QTL 38	2.876		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	31185002	76185002	Rat
737827	Hcar11	Hepatocarcinoma resistance QTL 11	4.4		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	6	46050607	116278722	Rat
724513	Uae14	Urinary albumin excretion QTL 14	6.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	46047353	91047353	Rat
2293839	Kiddil2	Kidney dilation QTL 2	4.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	26618314	86868070	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	20859430	113082285	Rat
9590140	Scort4	Serum corticosterone level QTL 4	14.49	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	44510974	89510974	Rat
2301964	Bp323	Blood pressure QTL 323	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	86868070	Rat
9590306	Scort18	Serum corticosterone level QTL 18	2.88	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	44510974	89510974	Rat
1578665	Bss16	Bone structure and strength QTL 16	4.4		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	6	33328841	78328841	Rat
2293841	Kiddil4	Kidney dilation QTL 4	4.4		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	26618314	86868070	Rat
1641898	Colcr4	Colorectal carcinoma resistance QTL4	3.71	0.0007	intestine integrity trait (VT:0010554)	well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)	6	30937632	75937632	Rat
1578668	Bmd14	Bone mineral density QTL 14	3.8		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	33328841	78328841	Rat
6893340	Cm77	Cardiac mass QTL 77	0.26	0.57	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	39028659	86867923	Rat
70199	Coreg1	Compensatory renal growth QTL 1	11.8		kidney mass (VT:0002707)	compensatory renal growth score (CMO:0001894)	6	14599473	63457687	Rat
2301972	Bp325	Blood pressure QTL 325	4.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	16089372	61967788	Rat
1300143	Rf14	Renal function QTL 14	2.92		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	40163183	85163183	Rat
1354664	Slep2	Serum leptin concentration QTL 2	4.49		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	6	22288257	67288257	Rat

Markers in Region

RH128250

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	45,501,733 - 45,501,947 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	48,134,933 - 48,135,146	NCBI	Rnor6.0
Rnor_5.0	6	56,836,808 - 56,837,021	UniSTS	Rnor5.0
RGSC_v3.4	6	46,747,240 - 46,747,453	UniSTS	RGSC3.4
Celera	6	44,723,605 - 44,723,818	UniSTS
Cytogenetic Map	6	q16	UniSTS

D12Ertd604e

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	45,501,751 - 45,501,978 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	48,134,951 - 48,135,177	NCBI	Rnor6.0
Rnor_5.0	6	56,836,826 - 56,837,052	UniSTS	Rnor5.0
RGSC_v3.4	6	46,747,258 - 46,747,484	UniSTS	RGSC3.4
Celera	6	44,723,623 - 44,723,849	UniSTS
Cytogenetic Map	6	q16	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012192	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262074	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC109110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC087633	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212052	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000060185 ⟹ ENSRNOP00000056930

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	51,116,747 - 51,230,452 (+)	Ensembl
mRatBN7.2 Ensembl	6	45,388,376 - 45,502,083 (+)	Ensembl
Rnor_6.0 Ensembl	6	48,021,771 - 48,135,241 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107949 ⟹ ENSRNOP00000095835

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	51,116,898 - 51,117,429 (+)	Ensembl
mRatBN7.2 Ensembl	6	45,388,522 - 45,389,053 (+)	Ensembl

RefSeq Acc Id:

NM_001012192 ⟹ NP_001012192

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	51,116,827 - 51,230,409 (+)	NCBI
mRatBN7.2	6	45,388,451 - 45,502,042 (+)	NCBI
Rnor_6.0	6	48,021,771 - 48,135,241 (+)	NCBI
Rnor_5.0	6	56,723,808 - 56,837,116 (+)	NCBI
RGSC_v3.4	6	46,633,907 - 46,747,548 (+)	RGD
Celera	6	44,611,430 - 44,723,913 (+)	RGD

Sequence:

show sequence

GGGTTCTGGCCGATCCCTGGTGAGGCGGGACTCGGGCTCTAAGGCTTGAGTAGTTCGGCAGGCA
GAGTATCATGGAAGACGACGCCCCGGTGATCTACGGGCTGGAATTTCAGGCACGTGCTCTAACA
CCTCAAACTGCGGAAACAGATGCCATTCGCTTCTTGGTTGGGACGCAGTCTCTTAAATATGATA
ATCAGATCCACATCATAGACTTTGATGACGAAAATAACATTATAAATAAAAATGTCCTCCTCCA
TCAAGCCGGTGAGATCTGGCACATCAGTGCCAGCCCAGCAGATAAAGGTGTCCTGGCCACCTGC
TACAACAAAACTTCAGACAGTCGAGTCCAGGCATGTGCAGCCGTGTGGAGGATGCCCAAGGAAT
TAGAATCTGGTAGCCACGAGTCCCCTGAAGACCCTGCAAGCACTGCGCAGACCCTGGAGCTGCT
CTGTCACCTTGACAACGGGGCCCAAGGCAACGTGGCCTGTGTCGTGTGGGAACCGATGGGGGAT
GGGAAGAAGGTCATTTCCCTGGCCGACAGCCACATACTTCTGTGGGACCTCCAGCCCAGCTCAA
GCCAAGCTGTGCTGGCCAGCTCAGCAGCACTGGAAGGAAGGGGACAGCTGAAGTTTACCTCGGG
CCGGTGGAGCCCACACCACAACTGTACCCAGGTGGCCACAGCCAGTGATACTACCCTCCGAGGA
TGGGATACACGGAGCATGAGCCAGATATACTGCATAGAGAACGCTCATGGGCAGCTGGTGCGTG
ACCTAGACTTCAACCCCAACAAGCAGTATTACCTCGCCAGCTGTGGAGATGACTGCAAGGTGAA
GTTCTGGGACACACGGAATGTCACCGAGCCTGTGAAGACCCTGGAGGAGCATTCCCACTGGGTG
TGGAGCGTGCGTTACAACCACTCTCACGACCAGCTGGTCCTCACTGGCAGCAGCGACAGCAGAG
TTATCCTGTCCAACATGGTGTCTATCTCCTCAGAGCCCTTTGGCCACCTGGTGGACGATGATGA
CGTCAGTGACCCAGAGGAGCACCATACTGAGAAGAGTAAGGAACCCCTTCAGGACAACGTTATT
GCCACCTATGAGGAGCATGAGGACAGCGTGTATGCTGTGGATTGGGCCTCAGCTGACCCATGGC
TGTTCGCTTCCCTGAGTTACGATGGGAGACTAGTTATCAACAGAGTCCCCAGGGCACTGAAGTA
CCACATACTGCTCTAGTGGCCCATGGCACTGCTGCTTGGTACTCGGCAAATTCTCAGAAATCTG
CAGCTACGAGGTAATTCCCTTCACAGACATCCCTCCTTGGGAGAACCAGCGTTGCTTCTCCAGG
AGCTCTAAGGACTGGAGCTACTGCCAGCAGCTCATCTGATGTTGTCAGCACACTGCTCAGCATG
GGAGGGAGCCATACTGGACACAGCATTCCTGTGTGAATTGATGGTTGCCCAGTCTCTGGTCGGT
TTCTGGTTTCTGTCTTAAGGGTGTTGGGAGTTTAACTTTTCCACAGTGTGTTTCCGCCTTCCTG
TTGTCATGAGATTACAAACTGAAATAAAGTCAGTGGGATGTGAAAAAAAAAAAAAAAAAAAAAA
AAA

hide sequence

RefSeq Acc Id:

XM_063262074 ⟹ XP_063118144

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	51,191,887 - 51,230,453 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001012192	(Get FASTA)	NCBI Sequence Viewer
	XP_063118144	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH87633	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000056930
	ENSRNOP00000056930.5
GenBank Protein	Q5PPK9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001012192 ⟸ NM_001012192

- UniProtKB:

Q5PPK9 (UniProtKB/Swiss-Prot), F1LNX7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQIHIIDFDDENNIINKNVLLHQA
GEIWHISASPADKGVLATCYNKTSDSRVQACAAVWRMPKELESGSHESPEDPASTAQTLELLCH
LDNGAQGNVACVVWEPMGDGKKVISLADSHILLWDLQPSSSQAVLASSAALEGRGQLKFTSGRW
SPHHNCTQVATASDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFW
DTRNVTEPVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDVS
DPEEHHTEKSKEPLQDNVIATYEEHEDSVYAVDWASADPWLFASLSYDGRLVINRVPRALKYHI
LL

hide sequence

Ensembl Acc Id:

ENSRNOP00000056930 ⟸ ENSRNOT00000060185

Ensembl Acc Id:

ENSRNOP00000095835 ⟸ ENSRNOT00000107949

RefSeq Acc Id:	XP_063118144 ⟸ XM_063262074
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5PPK9-F1-model_v2	AlphaFold	Q5PPK9	1-386	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694536

Promoter ID:

EPDNEW_R5060

Type:

multiple initiation site

Name:

Eipr1_1

Description:

EARP complex and GARP complex interacting protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	48,021,715 - 48,021,775	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305817	AgrOrtholog
BioCyc Gene	G2FUF-37961	BioCyc
Ensembl Genes	ENSRNOG00000009285	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000060185	ENTREZGENE
	ENSRNOT00000060185.5	UniProtKB/Swiss-Prot
Gene3D-CATH	2.130.10.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7320156	IMAGE-MGC_LOAD
InterPro	EIPR1	UniProtKB/Swiss-Prot
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/Swiss-Prot
	WD40_repeat	UniProtKB/Swiss-Prot
	WD40_repeat_CS	UniProtKB/Swiss-Prot
	WD40_repeat_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:362721	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:105636	IMAGE-MGC_LOAD
NCBI Gene	362721	ENTREZGENE
PANTHER	EARP AND GARP COMPLEX-INTERACTING PROTEIN 1	UniProtKB/Swiss-Prot
	PTHR14205	UniProtKB/Swiss-Prot
Pfam	Beta-prop_EIPR1	UniProtKB/Swiss-Prot
	WD40	UniProtKB/Swiss-Prot
PhenoGen	Eipr1	PhenoGen
PROSITE	WD_REPEATS_1	UniProtKB/Swiss-Prot
	WD_REPEATS_2	UniProtKB/Swiss-Prot
	WD_REPEATS_REGION	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000009285	RatGTEx
SMART	WD40	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50978	UniProtKB/Swiss-Prot
UniProt	A0A8I6AQG0_RAT	UniProtKB/TrEMBL
	A6HB20_RAT	UniProtKB/TrEMBL
	EIPR1_RAT	UniProtKB/Swiss-Prot
	F1LNX7	ENTREZGENE, UniProtKB/TrEMBL
	Q5PPK9	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-05-18	Eipr1	EARP complex and GARP complex interacting protein 1	Tssc1	tumor suppressing subtransferable candidate 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Tssc1	tumor suppressing subtransferable candidate 1	Tssc1_predicted	tumor suppressing subtransferable candidate 1 (predicted)	Symbol and Name updated	1559027	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD