Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nop16 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of NOP16 mRNA] | CTD | PMID:31150632 | Nop16 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Nop16 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of NOP16 mRNA | CTD | PMID:36331819 | Nop16 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Nop16 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of NOP16 mRNA | CTD | PMID:22206623 | Nop16 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Nop16 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of NOP16 mRNA] | CTD | PMID:22206623 | Nop16 | Rat | 1,3,5-trinitro-1,3,5-triazinane | decreases expression | EXP | | 6480464 | cyclonite results in decreased expression of NOP16 mRNA | CTD | PMID:25559034 | Nop16 | Rat | 17beta-estradiol | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Estradiol results in increased expression of NOP16 mRNA | CTD | PMID:31614463 | Nop16 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Nop16 (Mus musculus) | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether affects the expression of NOP16 mRNA | CTD | PMID:30294300 | Nop16 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Nop16 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in decreased methylation of NOP16 gene | CTD | PMID:21212295 | Nop16 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NOP16 mRNA | CTD | PMID:22903824 | Nop16 | Rat | 4,4'-sulfonyldiphenol | affects expression | ISO | NOP16 (Homo sapiens) | 6480464 | bisphenol S affects the expression of NOP16 protein | CTD | PMID:31945527 | Nop16 | Rat | aflatoxin B1 | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of NOP16 mRNA | CTD | PMID:27153756 | Nop16 | Rat | aflatoxin B1 | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [Aflatoxin B1 co-treated with beta-Naphthoflavone] results in decreased expression of NOP16 protein | CTD | PMID:39638853 | Nop16 | Rat | aflatoxin B1 | increases methylation | ISO | NOP16 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of NOP16 gene | CTD | PMID:27153756 | Nop16 | Rat | all-trans-retinoic acid | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of NOP16 mRNA | CTD | PMID:16054129|PMID:23724009 | Nop16 | Rat | arsane | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nop16 | Rat | arsenic atom | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nop16 | Rat | atrazine | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of NOP16 mRNA | CTD | PMID:22378314 | Nop16 | Rat | benzo[a]pyrene | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of NOP16 mRNA | CTD | PMID:20106945 | Nop16 | Rat | benzo[a]pyrene | increases methylation | ISO | NOP16 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of NOP16 promoter | CTD | PMID:27901495 | Nop16 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of NOP16 mRNA | CTD | PMID:19150397 | Nop16 | Rat | beta-naphthoflavone | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [Aflatoxin B1 co-treated with beta-Naphthoflavone] results in decreased expression of NOP16 protein | CTD | PMID:39638853 | Nop16 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NOP16 mRNA | CTD | PMID:25181051 | Nop16 | Rat | bisphenol A | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [ginger extract results in increased abundance of Oils, Volatile] inhibits the reaction [bisphenol A results more ... | CTD | PMID:33376534 | Nop16 | Rat | bisphenol A | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of NOP16 mRNA; bisphenol A results in decreased expression more ... | CTD | PMID:29275510|PMID:37567409 | Nop16 | Rat | bisphenol A | affects expression | ISO | NOP16 (Homo sapiens) | 6480464 | bisphenol A affects the expression of NOP16 mRNA | CTD | PMID:30903817 | Nop16 | Rat | cadmium atom | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NOP16 more ... | CTD | PMID:35301059 | Nop16 | Rat | cadmium dichloride | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of NOP16 mRNA | CTD | PMID:38568856 | Nop16 | Rat | cadmium dichloride | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NOP16 more ... | CTD | PMID:35301059 | Nop16 | Rat | carbon nanotube | increases expression | ISO | Nop16 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of NOP16 mRNA; Nanotubes, Carbon results in increased more ... | CTD | PMID:25554681 | Nop16 | Rat | chromium(6+) | affects expression | ISO | Nop16 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of NOP16 mRNA | CTD | PMID:28472532 | Nop16 | Rat | cisplatin | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of NOP16 mRNA | CTD | PMID:27594783 | Nop16 | Rat | cobalt dichloride | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of NOP16 mRNA | CTD | PMID:19320972|PMID:19376846 | Nop16 | Rat | cyclosporin A | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of NOP16 mRNA | CTD | PMID:20106945 | Nop16 | Rat | DDE | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of NOP16 mRNA | CTD | PMID:38568856 | Nop16 | Rat | deoxynivalenol | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | deoxynivalenol results in increased expression of NOP16 protein | CTD | PMID:39638853 | Nop16 | Rat | dexamethasone | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Dexamethasone results in decreased expression of NOP16 mRNA | CTD | PMID:12782123 | Nop16 | Rat | Dibutyl phosphate | affects expression | ISO | NOP16 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of NOP16 mRNA | CTD | PMID:37042841 | Nop16 | Rat | dimethyl sulfoxide | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Dimethyl Sulfoxide results in decreased expression of NOP16 mRNA | CTD | PMID:39709020 | Nop16 | Rat | dioxygen | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Oxygen deficiency results in decreased expression of NOP16 mRNA | CTD | PMID:26516004 | Nop16 | Rat | dioxygen | multiple interactions | ISO | Nop16 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of NOP16 mRNA | CTD | PMID:30529165 | Nop16 | Rat | dorsomorphin | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Nop16 | Rat | entinostat | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | entinostat results in increased expression of NOP16 mRNA | CTD | PMID:26272509 | Nop16 | Rat | entinostat | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Nop16 | Rat | enzyme inhibitor | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Nop16 | Rat | ethanol | increases expression | ISO | Nop16 (Mus musculus) | 6480464 | Ethanol results in increased expression of NOP16 mRNA | CTD | PMID:30319688 | Nop16 | Rat | ethyl methanesulfonate | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of NOP16 mRNA | CTD | PMID:23649840 | Nop16 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of NOP16 mRNA | CTD | PMID:24136188 | Nop16 | Rat | folic acid | decreases expression | ISO | Nop16 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of NOP16 mRNA | CTD | PMID:25629700 | Nop16 | Rat | folic acid | multiple interactions | ISO | Nop16 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of NOP16 mRNA] | CTD | PMID:22206623 | Nop16 | Rat | formaldehyde | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of NOP16 mRNA | CTD | PMID:23649840 | Nop16 | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of NOP16 gene | CTD | PMID:22079235 | Nop16 | Rat | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of NOP16 mRNA | CTD | PMID:24136188 | Nop16 | Rat | hydrogen peroxide | affects expression | ISO | NOP16 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of NOP16 mRNA | CTD | PMID:20044591 | Nop16 | Rat | isotretinoin | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of NOP16 mRNA | CTD | PMID:20436886 | Nop16 | Rat | lipopolysaccharide | multiple interactions | ISO | Nop16 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Lipopolysaccharides] results in decreased methylation of NOP16 gene | CTD | PMID:21212295 | Nop16 | Rat | lipopolysaccharide | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of NOP16 mRNA | CTD | PMID:35811015 | Nop16 | Rat | lipopolysaccharide | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of NOP16 mRNA | CTD | PMID:35811015 | Nop16 | Rat | manganese atom | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nop16 | Rat | manganese(0) | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nop16 | Rat | manganese(II) chloride | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nop16 | Rat | menadione | affects expression | ISO | NOP16 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of NOP16 mRNA | CTD | PMID:20044591 | Nop16 | Rat | methidathion | increases expression | ISO | Nop16 (Mus musculus) | 6480464 | methidathion results in increased expression of NOP16 mRNA | CTD | PMID:34813904 | Nop16 | Rat | methyl methanesulfonate | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of NOP16 mRNA | CTD | PMID:23649840 | Nop16 | Rat | methylisothiazolinone | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of NOP16 mRNA | CTD | PMID:31629900 | Nop16 | Rat | mono(2-ethylhexyl) phthalate | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of NOP16 mRNA | CTD | PMID:22017230 | Nop16 | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of NOP16 mRNA | CTD | PMID:24136188 | Nop16 | Rat | nickel atom | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Nickel results in increased expression of NOP16 mRNA | CTD | PMID:25583101 | Nop16 | Rat | Nivalenol | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | nivalenol results in increased expression of NOP16 protein | CTD | PMID:39638853 | Nop16 | Rat | paracetamol | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of NOP16 mRNA | CTD | PMID:21420995 | Nop16 | Rat | paracetamol | affects response to substance | ISO | NOP16 (Homo sapiens) | 6480464 | NOP16 gene polymorphism affects the susceptibility to Acetaminophen | CTD | PMID:26104854 | Nop16 | Rat | perfluorononanoic acid | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of NOP16 mRNA | CTD | PMID:32588087 | Nop16 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Nop16 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of NOP16 mRNA | CTD | PMID:36331819 | Nop16 | Rat | phenobarbital | decreases methylation | ISO | Nop16 (Mus musculus) | 6480464 | Phenobarbital results in decreased methylation of NOP16 gene | CTD | PMID:19233941 | Nop16 | Rat | pirinixic acid | multiple interactions | ISO | Nop16 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Nop16 | Rat | pirinixic acid | increases expression | ISO | Nop16 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of NOP16 mRNA | CTD | PMID:23811191 | Nop16 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Nop16 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of NOP16 mRNA | CTD | PMID:28903501 | Nop16 | Rat | resveratrol | decreases expression | ISO | Nop16 (Mus musculus) | 6480464 | resveratrol results in decreased expression of NOP16 protein | CTD | PMID:25505154 | Nop16 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of NOP16 mRNA | CTD | PMID:35811015 | Nop16 | Rat | SB 431542 | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of NOP16 more ... | CTD | PMID:27188386|PMID:37664457 | Nop16 | Rat | senecionine | decreases expression | ISO | Nop16 (Mus musculus) | 6480464 | senecionine results in decreased expression of NOP16 protein | CTD | PMID:35357534 | Nop16 | Rat | sodium arsenate | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | sodium arsenate results in decreased expression of NOP16 protein | CTD | PMID:38348393 | Nop16 | Rat | sodium arsenite | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of NOP16 mRNA | CTD | PMID:38568856 | Nop16 | Rat | sodium arsenite | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nop16 | Rat | sodium arsenite | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of NOP16 mRNA | CTD | PMID:34032870 | Nop16 | Rat | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of NOP16 mRNA | CTD | PMID:25993096 | Nop16 | Rat | temozolomide | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of NOP16 mRNA | CTD | PMID:31758290 | Nop16 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of NOP16 mRNA] | CTD | PMID:31150632 | Nop16 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of NOP16 mRNA | CTD | PMID:31150632 | Nop16 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of NOP16 mRNA | CTD | PMID:34492290 | Nop16 | Rat | thiram | decreases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Thiram results in decreased expression of NOP16 mRNA | CTD | PMID:38568856 | Nop16 | Rat | titanium dioxide | increases expression | ISO | Nop16 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of NOP16 mRNA | CTD | PMID:27760801 | Nop16 | Rat | trichostatin A | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of NOP16 mRNA | CTD | PMID:24935251|PMID:26272509 | Nop16 | Rat | trichostatin A | affects expression | ISO | NOP16 (Homo sapiens) | 6480464 | trichostatin A affects the expression of NOP16 mRNA | CTD | PMID:28542535 | Nop16 | Rat | trichostatin A | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Nop16 | Rat | valproic acid | affects expression | ISO | NOP16 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NOP16 mRNA | CTD | PMID:25979313 | Nop16 | Rat | valproic acid | increases expression | ISO | NOP16 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of NOP16 mRNA | CTD | PMID:23179753|PMID:26272509|PMID:28001369 | Nop16 | Rat | valproic acid | multiple interactions | ISO | NOP16 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | | |||||||||||||||||||






















