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Gene: Rhpn1 (rhophilin, Rho GTPase binding protein 1) Rattus norvegicus

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Symbol:

Rhpn1

Name:

rhophilin, Rho GTPase binding protein 1

RGD ID:

1305688

Description:

Predicted to be involved in negative regulation of stress fiber assembly. Predicted to act upstream of or within several processes, including focal adhesion assembly; glomerular filtration; and renal albumin absorption. Predicted to be located in plasma membrane. Orthologous to human RHPN1 (rhophilin Rho GTPase binding protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC300030; rhophilin-1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RHPN1 (rhophilin Rho GTPase binding protein 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Rhpn1 (rhophilin, Rho GTPase binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rhpn1 (rhophilin Rho GTPase binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RHPN1 (rhophilin Rho GTPase binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RHPN1 (rhophilin Rho GTPase binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rhpn1 (rhophilin Rho GTPase binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RHPN1 (rhophilin Rho GTPase binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RHPN1 (rhophilin Rho GTPase binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rhpn1 (rhophilin Rho GTPase binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Rhpn1 (rhophilin Rho GTPase binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CCND1 (cyclin D1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	RHPN1 (rhophilin Rho GTPase binding protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Rhpn1 (rhophilin, Rho GTPase binding protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	rhpn1 (rhophilin, Rho GTPase binding protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Rhp	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Rhp	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rhpn1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	rhpn1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	109,272,676 - 109,283,444 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	109,272,715 - 109,283,444 (+)	Ensembl				GRCr8
mRatBN7.2	7	107,391,948 - 107,402,713 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	107,391,984 - 107,402,713 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	109,131,058 - 109,141,795 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	111,354,729 - 111,365,466 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	111,300,639 - 111,311,380 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	116,738,999 - 116,749,791 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	116,739,062 - 116,748,715 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	116,631,562 - 116,642,335 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	113,665,425 - 113,675,102 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	103,753,891 - 103,764,620 (+)	NCBI		Celera
RGSC_v3.1	7	113,699,000 - 113,709,127 (+)	NCBI
Cytogenetic Map	7	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

polycystic ovary syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (ISO)

aflatoxin B1 (EXP)

aldehydo-D-glucose (ISO)

alpha-Zearalanol (EXP)

antirheumatic drug (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

Bufotalin (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

cobalt dichloride (EXP)

cyclosporin A (ISO)

D-glucose (ISO)

DDE (ISO)

dibutyl phthalate (ISO)

gentamycin (EXP)

glucose (ISO)

lipopolysaccharide (ISO)

N-methyl-4-phenylpyridinium (ISO)

O-methyleugenol (ISO)

okadaic acid (ISO)

paracetamol (EXP)

perfluorooctanoic acid (EXP)

propanal (ISO)

rotenone (ISO)

sodium arsenite (ISO)

sulforaphane (ISO)

sunitinib (ISO)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

focal adhesion assembly (ISO)

glomerular filtration (ISO)

kidney development (ISO)

negative regulation of stress fiber assembly (IBA,ISO)

plasma membrane bounded cell projection morphogenesis (ISO)

renal albumin absorption (ISO)

signal transduction (IEA)

Cellular Component

cell periphery (ISO)

plasma membrane (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8571126

Genomics

Comparative Map Data

Rhpn1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	109,272,676 - 109,283,444 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	109,272,715 - 109,283,444 (+)	Ensembl				GRCr8
mRatBN7.2	7	107,391,948 - 107,402,713 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	107,391,984 - 107,402,713 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	109,131,058 - 109,141,795 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	111,354,729 - 111,365,466 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	111,300,639 - 111,311,380 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	116,738,999 - 116,749,791 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	116,739,062 - 116,748,715 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	116,631,562 - 116,642,335 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	113,665,425 - 113,675,102 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	103,753,891 - 103,764,620 (+)	NCBI		Celera
RGSC_v3.1	7	113,699,000 - 113,709,127 (+)	NCBI
Cytogenetic Map	7	q34	NCBI

RHPN1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	143,364,255 - 143,384,221 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	143,368,810 - 143,384,221 (+)	Ensembl			hg38	GRCh38
GRCh37	8	144,451,046 - 144,466,391 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	144,522,400 - 144,537,533 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	8	144,522,532 - 144,535,964	NCBI
Celera	8	140,761,326 - 140,776,245 (+)	NCBI		Celera
Cytogenetic Map	8	q24.3	NCBI
HuRef	8	139,704,521 - 139,719,677 (+)	NCBI		HuRef
CHM1_1	8	144,491,261 - 144,506,805 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	144,511,888 - 144,531,868 (+)	NCBI		T2T-CHM13v2.0

Rhpn1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	75,576,097 - 75,586,268 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	75,576,129 - 75,587,334 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	75,704,246 - 75,714,419 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	75,704,280 - 75,715,485 (+)	Ensembl			mm10	GRCm38
MGSCv37	15	75,534,718 - 75,544,849 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	75,531,649 - 75,541,480 (+)	NCBI		MGSCv36	mm8
Celera	15	77,204,875 - 77,215,006 (+)	NCBI		Celera
Cytogenetic Map	15	D3	NCBI
cM Map	15	34.76	NCBI

Rhpn1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955454	2,086,212 - 2,097,728 (+)	Ensembl
ChiLan1.0	NW_004955454	2,086,054 - 2,099,018 (+)	NCBI	ChiLan1.0	ChiLan1.0

RHPN1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	160,845,741 - 160,860,231 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	136,363,286 - 136,378,950 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	140,115,455 - 140,131,070 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	143,126,560 - 143,150,235 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	143,135,016 - 143,150,235 (+)	Ensembl			panPan2	panpan1.1

RHPN1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	37,081,527 - 37,090,628 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	37,046,923 - 37,090,922 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	37,033,326 - 37,043,196 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	37,552,809 - 37,562,692 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	37,522,087 - 37,562,692 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	37,224,836 - 37,234,698 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	37,343,369 - 37,353,204 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	37,820,507 - 37,830,374 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Rhpn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	1,292,238 - 1,303,536 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	8,719,627 - 8,729,487 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	8,718,341 - 8,730,668 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RHPN1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	1,123,105 - 1,132,966 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	1,123,098 - 1,133,030 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	1,122,843 - 1,132,727 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RHPN1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	137,591,656 - 137,604,616 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	137,591,673 - 137,604,452 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666039	2,299,351 - 2,312,813 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rhpn1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624735	13,369,353 - 13,380,750 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624735	13,369,199 - 13,380,480 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rhpn1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	248,023,649 - 248,034,566 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rhpn1
66 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	71
Count of miRNA genes:	66
Interacting mature miRNAs:	71
Transcripts:	ENSRNOT00000010065
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	92388565	119280177	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	82111245	123048330	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	104186212	135371468	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	31770293	110435881	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	71621154	114982716	Rat
70159	Bp61	Blood pressure QTL 61		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	73618702	118618702	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	93302009	131686183	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	95485047	137014596	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	46307490	127866166	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	85043242	130043242	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	85497398	130497398	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	92362341	137014596	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	83626689	128626689	Rat
1331723	Bw25	Body weight QTL 25	3.348		body mass (VT:0001259)	body weight (CMO:0000012)	7	96700404	111672180	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	82111382	132099989	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	98549867	137014596	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
631201	Panci1	Pancreas inflammation QTL 1	0	0.001	pancreas integrity trait (VT:0010560)	percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)	7	73557047	118557047	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	82111245	123048330	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	40540077	123682549	Rat
2313102	Bmd79	Bone mineral density QTL 79	2.3	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	7	96700404	118618702	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	49682832	115766396	Rat
10450862	Kidm55	Kidney mass QTL 55	4.9		kidney mass (VT:0002707)	kidney weight (CMO:0000081)	7	72725037	117725037	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	100548246	137014596	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	82111245	134948181	Rat
10450856	Livw4	Liver weight QTL 4	3.8		liver mass (VT:0003402)	liver weight (CMO:0000092)	7	72725037	117725037	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	49682832	115766396	Rat
10402855	Bp379	Blood pressure QTL 379		0.21	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	78682549	123682549	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	49682832	115766396	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	71621154	119349044	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat

Markers in Region

D7Got96

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	7	109,273,440 - 109,273,572 (+)	Marker Load Pipeline
mRatBN7.2	7	107,392,709 - 107,392,841 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	116,739,788 - 116,739,919	NCBI	Rnor6.0
Rnor_5.0	7	116,632,332 - 116,632,463	UniSTS	Rnor5.0
RGSC_v3.4	7	113,666,150 - 113,666,282	RGD	RGSC3.4
RGSC_v3.4	7	113,666,151 - 113,666,282	UniSTS	RGSC3.4
Celera	7	103,754,617 - 103,754,748	UniSTS
RGSC_v3.1	7	113,700,380 - 113,700,512	RGD
RH 3.4 Map	7	780.2	RGD
RH 3.4 Map	7	780.2	UniSTS
RH 2.0 Map	7	615.4	RGD
Cytogenetic Map	7	q34	UniSTS

BB023497

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	107,401,427 - 107,401,515 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	116,748,506 - 116,748,593	NCBI	Rnor6.0
Rnor_5.0	7	116,641,050 - 116,641,137	UniSTS	Rnor5.0
RGSC_v3.4	7	113,674,869 - 113,674,956	UniSTS	RGSC3.4
Celera	7	103,763,335 - 103,763,422	UniSTS
Cytogenetic Map	7	q34	UniSTS

RH127365

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	107,401,425 - 107,401,615 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	116,748,504 - 116,748,693	NCBI	Rnor6.0
Rnor_5.0	7	116,641,048 - 116,641,237	UniSTS	Rnor5.0
RGSC_v3.4	7	113,674,867 - 113,675,056	UniSTS	RGSC3.4
Celera	7	103,763,333 - 103,763,522	UniSTS
RH 3.4 Map	7	778.7	UniSTS
Cytogenetic Map	7	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	65	160	91	90	59	37	59	6	299	135	11	139	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001305237	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241900	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241902	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078808	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC133673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000010065 ⟹ ENSRNOP00000010065

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	116,739,156 - 116,748,534 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000075837 ⟹ ENSRNOP00000067928

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	109,272,715 - 109,283,444 (+)	Ensembl
mRatBN7.2 Ensembl	7	107,391,984 - 107,402,713 (+)	Ensembl
Rnor_6.0 Ensembl	7	116,739,062 - 116,748,534 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000075958 ⟹ ENSRNOP00000067922

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	116,739,091 - 116,748,715 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076174 ⟹ ENSRNOP00000068139

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	116,745,061 - 116,746,654 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076614

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	116,747,087 - 116,747,912 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076670 ⟹ ENSRNOP00000068455

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	116,739,082 - 116,745,117 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076797

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	116,747,457 - 116,748,497 (+)	Ensembl

RefSeq Acc Id:

NM_001305237 ⟹ NP_001292166

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	109,272,715 - 109,283,444 (+)	NCBI
mRatBN7.2	7	107,391,984 - 107,402,713 (+)	NCBI
Rnor_6.0	7	116,739,062 - 116,749,791 (+)	NCBI
Celera	7	103,753,891 - 103,764,620 (+)	NCBI

Sequence:

show sequence

GGAGGGGACAGTCCGAGCAGCGCGCTGGTCCTCCCTGTAGCGCGAGGGACCTGCTGCTCGCAGC
TTCTCGGGGTCAGCGTCCGAGTGGGCAGCAATGATCCTCGAGGAGAGGCCAGATGGCCAGGGCA
CTGGCGAGGACAGCCCTCGTCAGCAGAACGACGGCAGCATCCGTAAGGGCCATGACTCCTTCGT
GCAAAACCAGCCTGGCCAGCTGCATAGTCACAGGGCTCGGCTCCACCAGCAGATCAGCAAGGAG
CTGCGCATGCGGACCGGTGCTGAAAACCTCTACAGAGCCACGAGCAACACCTGGGTCCGGGAGA
CGGTCGCTCTGGAGCTGAGCTACGTCAACTCCAACCTACAACTGCTGAAAGAGGAGCTGGCAGA
GCTGAGCTGCAACGCGGATGTGGACCAGCCAGAGGGTGAGAGTGTTACTATTCCCATGATCCCC
CTGGGCCTGAAGGAAACCAAGGAGTTGGACTGGGCCACACCGCTGAAGGAGCTGATCTCTGAGC
ACTTTGGAGAGGACGGTGCCTCCTATGAGACAGAGATCCAGGAACTAGAAGACCTGCGGCAGGC
TACGAGGACTCCCAGCAGGGACGAGGTGGGCCTGGATCTGCTTGCAGCCTACTATAGCCAGCTC
TGCTTCCTGGACGCACGTTTCTTCAGTCCTGCCAGGAGCCCAGGGCTACTCTTTCACTGGTACG
ACTCGCTCACGGGGGTCCCGGCACAGCAGCGGGCTCTGGCCTTCGAGAAGGGCAGTGTACTGTT
TAACATTGGGGCACTCCACACGCAGATCGGAGCACGGCAGGATTGCTCCTGCACCGAGGGCACC
AGCCAGGCCGCCGAGGCTTTCCAGAGGGCCGCCGGGGCCTTCAGACTCCTGAGAGAGAACTTCT
CCCATGCGCCAAGCCCGGACATGAGCGCCGCCTCTCTCTCCATGCTGGAGCAGCTCATGGTTGC
TCAGGCCCAGGAATGCATCTTCAGGGGCCTCTTGCTGAGGGCCTCGGCCACACCTGACATCTGT
CCAGATCAACTGCAGCTGGCTCAGGAAGCTACCCAGGTGGCGACCGAGTATGGGCTTGTGCACC
GGGCCATGGCCCAGCCCCCCGTCCGAGACTACCTGCCTGCCTCCTGGACTAACCTGGCACGTGT
CAAGGCTGAGCACTTCTGCGCCCTGGCCCACTATCACGCAGCCATGGCCCTCTGCGAAAGCACC
TCAGCCAAGGGTGAACTCTCAAGGCAGGAGGACATCTTCCAGCCCTCAGCTACCTGTGAGCCCC
AAGGTCCCACACTGCCGCAGCACCCAGAAGAGCGCAGGAAGCTTGCCAAGGCCCACCTGAAGCG
TGCCATCCTGGGCCAGGAGGAGGCGCTGCGGCTTCACACTTTGTGCAGAGTCCCGCGCAAGGTG
GACCTGCTACAGGTTGTGGTGACTCAGGCACTGAGGCGCTCCCTGACCAAGTACTCAGAGCTCG
AGCGTGAGGATGACTTCTTCGAGGCTATGGAGGCCCCCGACATCCAGCCCAAGACTCACCAGGC
CCCAGAGGTGAGCATACCTAGCCTGTCGCAGGTGAAGGTGACTGACTTCTTCCACAGGCTGGGA
CCCCTATCCGTGTTCTCAACCAAGAATCGATGGCAGTTGGTCGGGCCGGTGCACATGACTCGAG
GAGAGGGAGGTTTCGGGTTCACGCTGCGGGGAGACTCGCCAGTCCTCATCGCTGCCGTTGTCCC
TGGGGGTCAGGCTGAGTCTGCTGGCCTGAAGGAGGGTGACTACATCGTGTCTGTGAATGGGCAG
CCTTGCAAGTGGTGGAAACACGTAGAAGTGGTCACGCAGCTGAGGAGCATGGGCGAGGAAGGCG
TGAGCCTGCAGGTCGTGTCCTTGCTGCCCGGCCCCGAACCACGTGGCACGGGACCCCGACGGCC
AGCACTGCTGTGGAACCAGAGAGAATGTGGTTTTGAGACTCCGACGCCTGCACACACCCGACCC
TGGCCCATCCTCGGCTGGAGCCGCAAGAATAAACAAAGCAAGAGTGGGAGCCACCCTGACCCCT
GCACCAACAGGAACTGTATCACCTGCCCCTGAGCTGGACACCCCGTACCCCTGTGTGTCCAGGG
TGGCCGTGGGGGCCATACTCCTGTGTACACCATCCTGTAGCCAGCCCCAGCTAGCCAGGTGTGC
CTAGCGCATTGCCCTCTACTCTGGGGGACCATCAGGCTGCCCCTGCCTGGCTTAGAGATGTCTA
TTAAAAATGCTGGTCAGATGAGGCAAGTCTGAGTCAGCTACCAGAGCCGTGGCCACTTTACCCC
ACCCGAGATCTTCTCAGTGTAATCCAGACGCAGTGCTTACACTATCCTCCTGCAGCAGGCCTCT
AGGCCCCTGCCATGCCCCATCTACTCTTCGGCTGCCTGACTATCCTCACATCCAGTTTCTCTGG
GCACGTACCCTTATGGTCCTATCCTGACTGCGCCTGGTTCATAGTAGCCCTTCTGGTCACCACC
CTCCCTTGCTGGTTAGTCAGTTTCTCTGTATGTAAGATCCCAGCAAAGACATTTTCTCTCCAGT
CCCCTTATACTCCCCCCAACTTTCAAGCCCCCCTGTCTCCCATTCCACCTGCACCCATGCAGGT
CCTGGCAGGTTCCTCAGTAAGGTAGGCCCTGGACTCCAGAGGCACAGGATGGGGGCACCAGGTA
AGAAGCAGTCCTAAACTGTGCATGGCTGAAGCCATGGAGATGCTCTCCCTCAAAGGCCCTGGAG
GTTCAGCATGGAAACAGAAAGGCTGTATGTATCTCTCTGTGGTAGAGAATGCAAGAAACTCTGG
GCTCAGTCCCTGGAACTAGAAAAAAACAGAAACAAAAAAATTAGAGGGGGAGATTGCTCTCTGT
GACCACCAGGGGGCAGTGTCACTCATTCATGCAGCCCTAGGAGGCTGCAGCTCTTCCAACCCCC
ACGAATCTGAGAATCCGTGGACAGCCCAGGAAAGAGAAGCATCCAGCTCGGTACTCAGCAACCC
ACCCACACTCATCCTCCAGCTTCTGCCCAGGGGCTCCCAGGTGAGAGCACCTAGAGTCTGTGCT
CCAGATTGGCCTACACAGTCCAGGGCTCTGCCGCCCATCACCCTGTGCAGACATCTGTGTCAAG
GTCCAGCGGGTAAATGTAGTGTTTAAGCACGTGAGTCCGGAAGATCCAGGTACAGCTTTCTTCT
GACGTAGGAGAGGCTCCCAGGGGATCCAGGAGTGTCCCTTATCACTCACCTGGGACAATCTCCA
ACTCAGCAGAATGACCAAGGCCACTCAGGCTCAACACTTGCTAATTTTATTAATAAAACTGTAC
GTCAAGGAA

hide sequence

RefSeq Acc Id:

XM_006241900 ⟹ XP_006241962

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	109,272,678 - 109,282,373 (+)	NCBI
mRatBN7.2	7	107,391,949 - 107,401,661 (+)	NCBI
Rnor_6.0	7	116,739,000 - 116,748,739 (+)	NCBI
Rnor_5.0	7	116,631,562 - 116,642,335 (+)	NCBI

Sequence:

show sequence

ACAACACCAAGTTTTTGCAGGCGTGGCCTCCGCTCCGCTGCACCGGTCAGTCGGACCCTCCAGG
AGGGGACAGTCCGAGCAGCGCGCTGGTCCTCCCTGTAGCGCGAGGGACCTGCTGCTCGCAGCTT
CTCGGGGTCAGCGTCCGAGTGGGCAGCAATGATCCTCGAGGAGAGGCCAGATGGCCAGGGCACT
GGCGAGGACAGCCCTCGTCAGCAGAACGACGGCAGCATCCGTAAGGGCCATGACTCCTTCGTGC
AAAACCAGCCTGGCCAGCTGCATAGTCACAGGGCTCGGCTCCACCAGCAGATCAGCAAGGAGCT
GCGCATGCGGACCGGTGCTGAAAACCTCTACAGAGCCACGAGCAACACCTGGGTCCGGGAGACG
GTCGCTCTGGAGCTGAGCTACGTCAACTCCAACCTACAACTGCTGAAAGAGGAGCTGGCAGAGC
TGAGCTGCAACGCGGATGTGGACCAGCCAGAGGGTGAGAGTGTTACTATTCCCATGATCCCCCT
GGGCCTGAAGGAAACCAAGGAGTTGGACTGGGCCACACCGCTGAAGGAGCTGATCTCTGAGCAC
TTTGGAGAGGACGGTGCCTCCTATGAGACAGAGATCCAGGAACTAGAAGACCTGCGGCAGGCTA
CGAGGACTCCCAGCAGGGACGAGGTGGGCCTGGATCTGCTTGCAGCCTACTATAGCCAGCTCTG
CTTCCTGGACGCACGTTTCTTCAGTCCTGCCAGGAGCCCAGGGCTACTCTTTCACTGGTACGAC
TCGCTCACGGGGGTCCCGGCACAGCAGCGGGCTCTGGCCTTCGAGAAGGGCAGTGTACTGTTTA
ACATTGGGGCACTCCACACGCAGATCGGAGCACGGCAGGATTGCTCCTGCACCGAGGGCACCAG
CCAGGCCGCCGAGGCTTTCCAGAGGGCCGCCGGGGCCTTCAGACTCCTGAGAGAGAACTTCTCC
CATGCGCCAAGCCCGGACATGAGCGCCGCCTCTCTCTCCATGCTGGAGCAGCTCATGGTTGCTC
AGGCCCAGGAATGCATCTTCAGGGGCCTCTTGCTGAGGGCCTCGGCCACACCTGACATCTGTCC
AGATCAACTGCAGCTGGCTCAGGAAGCTACCCAGGTGGCGACCGAGTATGGGCTTGTGCACCGG
GCCATGGCCCAGCCCCCCGTCCGAGACTACCTGCCTGCCTCCTGGACTAACCTGGCACGTGTCA
AGGCTGAGCACTTCTGCGCCCTGGCCCACTATCACGCAGCCATGGCCCTCTGCGAAAGCACCTC
AGCAGCCAAGGGTGAACTCTCAAGGCAGGAGGACATCTTCCAGCCCTCAGCTACCTGTGAGCCC
CAAGGTCCCACACTGCCGCAGCACCCAGAAGAGCGCAGGAAGCTTGCCAAGGCCCACCTGAAGC
GTGCCATCCTGGGCCAGGAGGAGGCGCTGCGGCTTCACACTTTGTGCAGAGTCCCGCGCAAGGT
GGACCTGCTACAGGTTGTGGTGACTCAGGCACTGAGGCGCTCCCTGACCAAGTACTCAGAGCTC
GAGCGTGAGGATGACTTCTTCGAGGCTATGGAGGCCCCCGACATCCAGCCCAAGACTCACCAGG
CCCCAGAGGTGAGCATACCTAGCCTGTCGCAGGTGAAGGTGACTGACTTCTTCCACAGGCTGGG
ACCCCTATCCGTGTTCTCAACCAAGAATCGATGGCAGTTGGTCGGGCCGGTGCACATGACTCGA
GGAGAGGGAGGTTTCGGGTTCACGCTGCGGGGAGACTCGCCAGTCCTCATCGCTGCCGTTGTCC
CTGGGGGTCAGGCTGAGTCTGCTGGCCTGAAGGAGGGTGACTACATCGTGTCTGTGAATGGGCA
GCCTTGCAAGTGGTGGAAACACGTAGAAGTGGTCACGCAGCTGAGGAGCATGGGCGAGGAAGGC
GTGAGCCTGCAGGTCGTGTCCTTGCTGCCCGGCCCCGAACCACGTGGCACGGGACCCCGACGGC
CAGCACTGCTGTGGAACCAGAGAGAATGTGGTTTTGAGACTCCGACGCCTGCACACACCCGACC
CTGGCCCATCCTCGGCTGGAGCCGCAAGAATAAACAAAGCAAGAGTGGGAGCCACCCTGACCCC
TGCACCAACAGGAACTGTATCACCTGCCCCTGAGCTGGACACCCCGTACCCCTGTGTGTCCAGG
GTGGCCGTGGGGGCCATACTCCTGTGTACACCATCCTGTAGCCAGCCCCAGCTAGCCAGGTGTG
CCTAGCGCATTGCCCTCTACTCTGGGGGACCATCAGGCTGCCCCTGCCTGGCTTAGAGATGTCT
ATTAAAAATGCTGGTCAGATGAGGCAAGTCTGAGTCAGCTACCAGA

hide sequence

RefSeq Acc Id:

XM_006241901 ⟹ XP_006241963

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	109,272,676 - 109,282,373 (+)	NCBI
mRatBN7.2	7	107,391,948 - 107,401,362 (+)	NCBI
Rnor_6.0	7	116,738,999 - 116,748,392 (+)	NCBI
Rnor_5.0	7	116,631,562 - 116,642,335 (+)	NCBI

Sequence:

show sequence

GACAACACCAAGTTTTTGCAGGCGTGGCCTCCGCTCCGCTGCACCGGTCAGTCGGACCCTCCAG
GAGGGGACAGTCCGAGCAGCGCGCTGGTCCTCCCTGTAGCGCGAGGGACCTGCTGCTCGCAGCT
TCTCGGGGTCAGCGTCCGAGTGGGCAGCAATGATCCTCGAGGAGAGGCCAGATGGCCAGGGCAC
TGGCGAGGACAGCCCTCGTCAGCAGAACGACGGCAGCATCCGTAAGGGCCATGACTCCTTCGTG
CAAAACCAGCCTGGCCAGCTGCATAGTCACAGGGCTCGGCTCCACCAGCAGATCAGCAAGGAGC
TGCGCATGCGGACCGGTGCTGAAAACCTCTACAGAGCCACGAGCAACACCTGGGTCCGGGAGAC
GGTCGCTCTGGAGCTGAGCTACGTCAACTCCAACCTACAACTGCTGAAAGAGGAGCTGGCAGAG
CTGAGCTGCAACGCGGATGTGGACCAGCCAGAGGGTGAGAGTGTTACTATTCCCATGATCCCCC
TGGGCCTGAAGGAAACCAAGGAGTTGGACTGGGCCACACCGCTGAAGGAGCTGATCTCTGAGCA
CTTTGGAGAGGACGGTGCCTCCTATGAGACAGAGATCCAGGAACTAGAAGACCTGCGGCAGGCT
ACGAGGACTCCCAGCAGGGACGAGGTGGGCCTGGATCTGCTTGCAGCCTACTATAGCCAGCTCT
GCTTCCTGGACGCACGTTTCTTCAGTCCTGCCAGGAGCCCAGGGCTACTCTTTCACTGGTACGA
CTCGCTCACGGGGGTCCCGGCACAGCAGCGGGCTCTGGCCTTCGAGAAGGGCAGTGTACTGTTT
AACATTGGGGCACTCCACACGCAGATCGGAGCACGGCAGGATTGCTCCTGCACCGAGGGCACCA
GCCAGGCCGCCGAGGCTTTCCAGAGGGCCGCCGGGGCCTTCAGACTCCTGAGAGAGAACTTCTC
CCATGCGCCAAGCCCGGACATGAGCGCCGCCTCTCTCTCCATGCTGGAGCAGCTCATGGTTGCT
CAGGCCCAGGAATGCATCTTCAGGGGCCTCTTGCTGAGGGCCTCGGCCACACCTGACATCTGTC
CAGATCAACTGCAGCTGGCTCAGGAAGCTACCCAGGTGGCGACCGAGTATGGGCTTGTGCACCG
GGCCATGGCCCAGCCCCCCGTCCGAGACTACCTGCCTGCCTCCTGGACTAACCTGGCACGTGTC
AAGGCTGAGCACTTCTGCGCCCTGGCCCACTATCACGCAGCCATGGCCCTCTGCGAAAGCACCT
CAGCAGCCAAGGGTGAACTCTCAAGGCAGGAGGACATCTTCCAGCCCTCAGCTACCTGTGAGCC
CCAAGGTCCCACACTGCCGCAGCACCCAGAAGAGCGCAGGAAGCTTGCCAAGGCCCACCTGAAG
CGTGCCATCCTGGGCCAGGAGGAGGCGCTGCGGCTTCACACTTTGTGCAGAGTCCCGCGCAAGG
TGGACCTGCTACAGGTTGTGGTGACTCAGGCACTGAGGCGCTCCCTGACCAAGTACTCAGAGCT
CGAGCGTGAGGATGACTTCTTCGAGGCTATGGAGGCCCCCGACATCCAGCCCAAGACTCACCAG
GCCCCAGAGGTGAGCATACCTAGCCTGTCGCAGGTGAAGGTGACTGACTTCTTCCACAGGCTGG
GACCCCTATCCGTGTTCTCAACCAAGAATCGATGGCAGTTGGTCGGGCCGGTGCACATGACTCG
AGGAGAGGGAGGTTTCGGGTTCACGCTGCGGGGAGACTCGCCAGTCCTCATCGCTGCCGTTGTC
CCTGGGGGTCAGGCTGAGTCTGCTGGCCTGAAGGAGGGTGACTACATCGTGTCTGTGAATGGGC
AGCCTTGCAAGTGGTGGAAACACGTAGAAGTGGTCACGCAGCTGAGGAGCATGGGCGAGGAAGG
CGTGAGCCTGCAGGTCGTGTCCTTGCTGCCCGGCCCCGAACCACGTGGCACGGGTGGCCACAGG
TAGGTCAGGCAGTGATGGCTGACTACATCCACTGCTGTTATGACCGTAGGGACCCCGACGGCCA
GCACTGCTGTGGAACCA

hide sequence

RefSeq Acc Id:

XM_039078808 ⟹ XP_038934736

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	109,278,491 - 109,282,373 (+)	NCBI
mRatBN7.2	7	107,397,751 - 107,401,661 (+)	NCBI

RefSeq Acc Id:

XM_063263274 ⟹ XP_063119344

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	109,272,683 - 109,282,373 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001292166	(Get FASTA)	NCBI Sequence Viewer
	XP_006241962	(Get FASTA)	NCBI Sequence Viewer
	XP_006241963	(Get FASTA)	NCBI Sequence Viewer
	XP_038934736	(Get FASTA)	NCBI Sequence Viewer
	XP_063119344	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM16055	(Get FASTA)	NCBI Sequence Viewer
	EDM16056	(Get FASTA)	NCBI Sequence Viewer
	EDM16057	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000067928
	ENSRNOP00000067928.3

RefSeq Acc Id:	XP_006241963 ⟸ XM_006241901
- Peptide Label:	isoform X2
- UniProtKB:	A6HS15 (UniProtKB/TrEMBL)
- Sequence:	show sequence MILEERPDGQGTGEDSPRQQNDGSIRKGHDSFVQNQPGQLHSHRARLHQQISKELRMRTGAENL YRATSNTWVRETVALELSYVNSNLQLLKEELAELSCNADVDQPEGESVTIPMIPLGLKETKELD WATPLKELISEHFGEDGASYETEIQELEDLRQATRTPSRDEVGLDLLAAYYSQLCFLDARFFSP ARSPGLLFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDCSCTEGTSQAAEAFQRA AGAFRLLRENFSHAPSPDMSAASLSMLEQLMVAQAQECIFRGLLLRASATPDICPDQLQLAQEA TQVATEYGLVHRAMAQPPVRDYLPASWTNLARVKAEHFCALAHYHAAMALCESTSAAKGELSRQ EDIFQPSATCEPQGPTLPQHPEERRKLAKAHLKRAILGQEEALRLHTLCRVPRKVDLLQVVVTQ ALRRSLTKYSELEREDDFFEAMEAPDIQPKTHQAPEVSIPSLSQVKVTDFFHRLGPLSVFSTKN RWQLVGPVHMTRGEGGFGFTLRGDSPVLIAAVVPGGQAESAGLKEGDYIVSVNGQPCKWWKHVE VVTQLRSMGEEGVSLQVVSLLPGPEPRGTGGHR hide sequence

RefSeq Acc Id:	XP_006241962 ⟸ XM_006241900
- Peptide Label:	isoform X1
- UniProtKB:	A6HS15 (UniProtKB/TrEMBL)
- Sequence:	show sequence MILEERPDGQGTGEDSPRQQNDGSIRKGHDSFVQNQPGQLHSHRARLHQQISKELRMRTGAENL YRATSNTWVRETVALELSYVNSNLQLLKEELAELSCNADVDQPEGESVTIPMIPLGLKETKELD WATPLKELISEHFGEDGASYETEIQELEDLRQATRTPSRDEVGLDLLAAYYSQLCFLDARFFSP ARSPGLLFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDCSCTEGTSQAAEAFQRA AGAFRLLRENFSHAPSPDMSAASLSMLEQLMVAQAQECIFRGLLLRASATPDICPDQLQLAQEA TQVATEYGLVHRAMAQPPVRDYLPASWTNLARVKAEHFCALAHYHAAMALCESTSAAKGELSRQ EDIFQPSATCEPQGPTLPQHPEERRKLAKAHLKRAILGQEEALRLHTLCRVPRKVDLLQVVVTQ ALRRSLTKYSELEREDDFFEAMEAPDIQPKTHQAPEVSIPSLSQVKVTDFFHRLGPLSVFSTKN RWQLVGPVHMTRGEGGFGFTLRGDSPVLIAAVVPGGQAESAGLKEGDYIVSVNGQPCKWWKHVE VVTQLRSMGEEGVSLQVVSLLPGPEPRGTGPRRPALLWNQRECGFETPTPAHTRPWPILGWSRK NKQSKSGSHPDPCTNRNCITCP hide sequence

RefSeq Acc Id:

NP_001292166 ⟸ NM_001305237

- UniProtKB:

A0A096MIZ0 (UniProtKB/TrEMBL), A6HS15 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MILEERPDGQGTGEDSPRQQNDGSIRKGHDSFVQNQPGQLHSHRARLHQQISKELRMRTGAENL
YRATSNTWVRETVALELSYVNSNLQLLKEELAELSCNADVDQPEGESVTIPMIPLGLKETKELD
WATPLKELISEHFGEDGASYETEIQELEDLRQATRTPSRDEVGLDLLAAYYSQLCFLDARFFSP
ARSPGLLFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDCSCTEGTSQAAEAFQRA
AGAFRLLRENFSHAPSPDMSAASLSMLEQLMVAQAQECIFRGLLLRASATPDICPDQLQLAQEA
TQVATEYGLVHRAMAQPPVRDYLPASWTNLARVKAEHFCALAHYHAAMALCESTSAKGELSRQE
DIFQPSATCEPQGPTLPQHPEERRKLAKAHLKRAILGQEEALRLHTLCRVPRKVDLLQVVVTQA
LRRSLTKYSELEREDDFFEAMEAPDIQPKTHQAPEVSIPSLSQVKVTDFFHRLGPLSVFSTKNR
WQLVGPVHMTRGEGGFGFTLRGDSPVLIAAVVPGGQAESAGLKEGDYIVSVNGQPCKWWKHVEV
VTQLRSMGEEGVSLQVVSLLPGPEPRGTGPRRPALLWNQRECGFETPTPAHTRPWPILGWSRKN
KQSKSGSHPDPCTNRNCITCP

hide sequence

Ensembl Acc Id:

ENSRNOP00000067928 ⟸ ENSRNOT00000075837

Ensembl Acc Id:

ENSRNOP00000010065 ⟸ ENSRNOT00000010065

Ensembl Acc Id:

ENSRNOP00000067922 ⟸ ENSRNOT00000075958

Ensembl Acc Id:

ENSRNOP00000068139 ⟸ ENSRNOT00000076174

Ensembl Acc Id:

ENSRNOP00000068455 ⟸ ENSRNOT00000076670

RefSeq Acc Id:	XP_038934736 ⟸ XM_039078808
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063119344 ⟸ XM_063263274
- Peptide Label:	isoform X3
- UniProtKB:	A6HS15 (UniProtKB/TrEMBL)

Protein Domains

BRO1 PDZ REM-1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LY81-F1-model_v2	AlphaFold	F1LY81	1-661	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695393

Promoter ID:

EPDNEW_R5914

Type:

initiation region

Name:

Rhpn1_1

Description:

rhophilin, Rho GTPase binding protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	116,739,071 - 116,739,131	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305688	AgrOrtholog
BioCyc Gene	G2FUF-32986	BioCyc
Ensembl Genes	ENSRNOG00000007597	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000075837	ENTREZGENE
	ENSRNOT00000075837.4	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.280	UniProtKB/TrEMBL
	2.30.42.10	UniProtKB/TrEMBL
	HR1 repeat	UniProtKB/TrEMBL
InterPro	BRO1	UniProtKB/TrEMBL
	BRO1_sf	UniProtKB/TrEMBL
	HR1_rho-bd	UniProtKB/TrEMBL
	HR1_rpt_sf	UniProtKB/TrEMBL
	PDZ/DHR/GLGF	UniProtKB/TrEMBL
	PDZ_sf	UniProtKB/TrEMBL
	Rhophilin-1_BRO1	UniProtKB/TrEMBL
	RHPN1_2	UniProtKB/TrEMBL
KEGG Report	rno:300030	UniProtKB/TrEMBL
NCBI Gene	300030	ENTREZGENE
PANTHER	RHOPHILIN	UniProtKB/TrEMBL
	RHOPHILIN-1	UniProtKB/TrEMBL
Pfam	BRO1	UniProtKB/TrEMBL
	HR1	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
PhenoGen	Rhpn1	PhenoGen
PROSITE	BRO1	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
	REM_1	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000007597	RatGTEx
SMART	BRO1	UniProtKB/TrEMBL
	Hr1	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
Superfamily-SCOP	PDZ	UniProtKB/TrEMBL
	PKN_effector	UniProtKB/TrEMBL
UniProt	A0A096MIZ0	ENTREZGENE, UniProtKB/TrEMBL
	A6HS15	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Rhpn1	rhophilin, Rho GTPase binding protein 1	Rhpn1_predicted	rhophilin, Rho GTPase binding protein 1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Rhpn1_predicted	rhophilin, Rho GTPase binding protein 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD