Cadm2 (cell adhesion molecule 2) - Rat Genome Database

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Gene: Cadm2 (cell adhesion molecule 2) Rattus norvegicus
Analyze
Symbol: Cadm2
Name: cell adhesion molecule 2
RGD ID: 1305678
Description: Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules. Located in axon and neuronal cell body membrane. Human ortholog(s) of this gene implicated in autism spectrum disorder; malignant astrocytoma; obesity; psoriasis; and type 2 diabetes mellitus. Orthologous to human CADM2 (cell adhesion molecule 2); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Igsf4d; immunoglobulin superfamily member 4D; immunoglobulin superfamily, member 4; LOC360687; Necl-3; nectin-like protein 3; synaptic cell adhesion molecule 2; SynCAM 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Cadm2Tn(sb-T2/Bart3)2.180Mcwi  
Genetic Models: F344-Cadm2Tn(sb-T2/Bart3)2.180Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81117,994,856 - 18,971,895 (-)NCBIGRCr8
mRatBN7.2114,548,367 - 5,525,420 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl114,555,159 - 5,525,400 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1113,151,919 - 14,120,737 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0115,945,843 - 6,914,696 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0115,050,918 - 6,019,774 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0114,175,078 - 4,397,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl114,174,881 - 4,397,361 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0117,871,257 - 8,090,100 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4114,273,771 - 5,330,393 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1114,273,770 - 4,503,107 (-)NCBI
Celera114,517,639 - 5,495,475 (-)NCBICelera
Cytogenetic Map11p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axon  (IDA)
neuronal cell body membrane  (IBA,IDA,IEA)
synapse  (IEA)

Molecular Function
protein binding  (IPI,ISO)

References

References - curated
# Reference Title Reference Citation
1. A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. Casey JP, etal., Hum Genet. 2012 Apr;131(4):565-79. doi: 10.1007/s00439-011-1094-6. Epub 2011 Oct 14.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. A novel splicing variant of CADM2 as a protective transcript of psoriasis. Hiruma A, etal., Biochem Biophys Res Commun. 2011 Sep 9;412(4):626-32. doi: 10.1016/j.bbrc.2011.08.013. Epub 2011 Aug 11.
4. Downregulation of microRNA‑182 inhibits cell viability, invasion and angiogenesis in retinoblastoma through inhibition of the PI3K/AKT pathway and CADM2 upregulation. Huang YX, etal., Int J Oncol. 2018 Dec;53(6):2615-2626. doi: 10.3892/ijo.2018.4587. Epub 2018 Oct 9.
5. Genetic predictors of weight loss in overweight and obese subjects. Lamiquiz-Moneo I, etal., Sci Rep. 2019 Jul 24;9(1):10770. doi: 10.1038/s41598-019-47283-5.
6. CADM2 inhibits human glioma proliferation, migration and invasion. Liu N, etal., Oncol Rep. 2019 Apr;41(4):2273-2280. doi: 10.3892/or.2019.7010. Epub 2019 Feb 13.
7. Nectin-like proteins mediate axon Schwann cell interactions along the internode and are essential for myelination. Maurel P, etal., J Cell Biol. 2007 Aug 27;178(5):861-74.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Exploring single nucleotide polymorphisms previously related to obesity and metabolic traits in pediatric-onset type 2 diabetes. Miranda-Lora AL, etal., Acta Diabetol. 2017 Jul;54(7):653-662. doi: 10.1007/s00592-017-0987-9. Epub 2017 Apr 12.
10. The adhesion molecule Necl-3/SynCAM-2 localizes to myelinated axons, binds to oligodendrocytes and promotes cell adhesion. Pellissier F, etal., BMC Neurosci. 2007 Oct 29;8:90.
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Low CADM2 expression predicts high recurrence risk of hepatocellular carcinoma patients after hepatectomy. Yang S, etal., J Cancer Res Clin Oncol. 2014 Jan;140(1):109-16. doi: 10.1007/s00432-013-1536-8. Epub 2013 Nov 17.
Additional References at PubMed
PMID:22871113   PMID:29039453  


Genomics

Comparative Map Data
Cadm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81117,994,856 - 18,971,895 (-)NCBIGRCr8
mRatBN7.2114,548,367 - 5,525,420 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl114,555,159 - 5,525,400 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1113,151,919 - 14,120,737 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0115,945,843 - 6,914,696 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0115,050,918 - 6,019,774 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0114,175,078 - 4,397,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl114,174,881 - 4,397,361 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0117,871,257 - 8,090,100 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4114,273,771 - 5,330,393 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1114,273,770 - 4,503,107 (-)NCBI
Celera114,517,639 - 5,495,475 (-)NCBICelera
Cytogenetic Map11p12NCBI
CADM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38384,958,989 - 86,074,429 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl384,958,989 - 86,074,429 (+)EnsemblGRCh38hg38GRCh38
GRCh37385,008,140 - 86,123,579 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36385,858,322 - 86,200,641 (+)NCBINCBI36Build 36hg18NCBI36
Build 34385,858,321 - 86,200,638NCBI
Celera385,754,715 - 86,870,332 (+)NCBICelera
Cytogenetic Map3p12.1NCBI
HuRef385,021,486 - 86,137,517 (+)NCBIHuRef
CHM1_1384,960,228 - 86,075,698 (+)NCBICHM1_1
T2T-CHM13v2.0385,024,005 - 86,146,272 (+)NCBIT2T-CHM13v2.0
Cadm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391666,452,302 - 67,417,825 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1666,452,307 - 67,417,796 (-)EnsemblGRCm39 Ensembl
GRCm381666,655,416 - 67,620,917 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1666,655,421 - 67,620,908 (-)EnsemblGRCm38mm10GRCm38
MGSCv371666,655,666 - 67,621,153 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361666,579,334 - 67,539,146 (-)NCBIMGSCv36mm8
Celera1666,933,305 - 67,895,289 (-)NCBICelera
Cytogenetic Map16C1.3- C2NCBI
cM Map1637.96NCBI
Cadm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554077,077,887 - 7,355,853 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554077,070,355 - 7,355,841 (-)NCBIChiLan1.0ChiLan1.0
CADM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2285,096,880 - 86,213,586 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1385,869,821 - 86,218,375 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0385,076,738 - 86,200,515 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1387,200,283 - 88,318,087 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl387,200,482 - 88,310,438 (+)Ensemblpanpan1.1panPan2
CADM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1311,872,005 - 2,931,942 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl311,879,585 - 2,931,452 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha311,923,826 - 2,990,923 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0311,868,368 - 2,932,068 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl311,869,206 - 2,931,641 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1311,838,209 - 2,904,288 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0311,892,951 - 2,955,130 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0312,224,471 - 3,287,100 (-)NCBIUU_Cfam_GSD_1.0
Cadm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049713,300,333 - 4,297,753 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366103,305,551 - 3,598,837 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366103,304,556 - 4,297,745 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CADM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13169,688,958 - 170,014,005 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113169,681,947 - 170,753,114 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213180,745,385 - 180,922,682 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CADM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12290,879,537 - 91,994,144 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604174,824,798 - 75,904,006 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cadm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247891,245,304 - 2,314,562 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247891,245,224 - 2,316,519 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cadm2
3142 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:157
Count of miRNA genes:125
Interacting mature miRNAs:131
Transcripts:ENSRNOT00000046370
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)11121836709Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat

Markers in Region
D11Got5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,094,127 - 5,094,363 (+)MAPPERmRatBN7.2
Rnor_6.01112,960,913 - 12,961,148NCBIRnor6.0
Rnor_5.01116,620,702 - 16,620,937UniSTSRnor5.0
RGSC_v3.4114,815,879 - 4,816,115RGDRGSC3.4
RGSC_v3.4114,815,880 - 4,816,115UniSTSRGSC3.4
RGSC_v3.1114,815,880 - 4,816,115RGD
Celera115,066,743 - 5,066,978UniSTS
RH 3.4 Map110.0RGD
RH 3.4 Map110.0UniSTS
RH 2.0 Map11775.5RGD
Cytogenetic Map11p12UniSTS
D11Got1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,094,166 - 5,094,350 (+)MAPPERmRatBN7.2
Rnor_6.01112,960,952 - 12,961,135NCBIRnor6.0
Rnor_5.01116,620,741 - 16,620,924UniSTSRnor5.0
RGSC_v3.4114,815,918 - 4,816,102RGDRGSC3.4
RGSC_v3.4114,815,919 - 4,816,102UniSTSRGSC3.4
RGSC_v3.1114,815,918 - 4,816,102RGD
Celera115,066,782 - 5,066,965UniSTS
RH 2.0 Map11803.6RGD
Cytogenetic Map11p12UniSTS
D11Mco8  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2114,728,703 - 4,728,950 (+)MAPPERmRatBN7.2
Rnor_6.0114,349,717 - 4,349,963NCBIRnor6.0
Rnor_5.0118,043,362 - 8,043,608UniSTSRnor5.0
Celera114,701,802 - 4,702,048UniSTS
Cytogenetic Map11p12UniSTS
BF386655  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2114,569,659 - 4,569,834 (+)MAPPERmRatBN7.2
Rnor_6.0114,188,829 - 4,189,003NCBIRnor6.0
Rnor_5.0117,885,091 - 7,885,265UniSTSRnor5.0
RGSC_v3.4114,288,166 - 4,288,340UniSTSRGSC3.4
Celera114,543,279 - 4,543,453UniSTS
Cytogenetic Map11p12UniSTS
BF387017  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2114,907,960 - 4,908,141 (+)MAPPERmRatBN7.2
Rnor_6.01112,760,789 - 12,760,969NCBIRnor6.0
Rnor_5.01116,421,247 - 16,421,427UniSTSRnor5.0
RGSC_v3.4114,628,760 - 4,628,940UniSTSRGSC3.4
Celera114,880,105 - 4,880,285UniSTS
Cytogenetic Map11p12UniSTS
BF387497  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2115,474,121 - 5,474,271 (+)MAPPERmRatBN7.2
Rnor_6.01113,346,949 - 13,347,098NCBIRnor6.0
Rnor_5.01117,000,642 - 17,000,791UniSTSRnor5.0
RGSC_v3.4115,277,567 - 5,277,716UniSTSRGSC3.4
Celera115,444,945 - 5,445,094UniSTS
Cytogenetic Map11p12UniSTS
AU047486  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera115,443,105 - 5,443,379UniSTS
Cytogenetic Map11p12UniSTS
RH137821  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2114,958,286 - 4,958,408 (+)MAPPERmRatBN7.2
Rnor_6.01112,824,848 - 12,824,969NCBIRnor6.0
Rnor_5.01116,484,637 - 16,484,758UniSTSRnor5.0
RGSC_v3.4114,680,219 - 4,680,340UniSTSRGSC3.4
Celera114,931,153 - 4,931,274UniSTS
Cytogenetic Map11p12UniSTS
AU048452  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2114,662,018 - 4,662,192 (+)MAPPERmRatBN7.2
Rnor_6.0114,280,946 - 4,281,119NCBIRnor6.0
Rnor_5.0117,977,193 - 7,977,366UniSTSRnor5.0
RGSC_v3.4114,383,860 - 4,384,033UniSTSRGSC3.4
Celera114,635,599 - 4,635,772UniSTS
Cytogenetic Map11p12UniSTS


Genetic Models
This gene Cadm2 is modified in the following models/strains:


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 58 4
Low 1 20 6 1 1 1 14 10 25 6 1
Below cutoff 2 21 20 10 18 10 7 9 2 24 11 4 7

Sequence


RefSeq Acc Id: ENSRNOT00000046370   ⟹   ENSRNOP00000040899
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl114,555,159 - 5,524,775 (-)Ensembl
Rnor_6.0 Ensembl114,175,078 - 4,397,361 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000087133   ⟹   ENSRNOP00000073563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl114,555,159 - 4,711,060 (-)Ensembl
Rnor_6.0 Ensembl114,174,881 - 4,332,255 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095471   ⟹   ENSRNOP00000093597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl114,555,159 - 4,780,494 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099827   ⟹   ENSRNOP00000088953
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl114,555,159 - 4,869,533 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108768   ⟹   ENSRNOP00000082922
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl114,555,159 - 5,525,400 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111554   ⟹   ENSRNOP00000088030
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl114,555,159 - 5,525,400 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000115818   ⟹   ENSRNOP00000081968
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl114,555,159 - 4,707,043 (-)Ensembl
RefSeq Acc Id: NM_001047102   ⟹   NP_001040567
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81117,994,856 - 18,971,886 (-)NCBI
mRatBN7.2114,548,367 - 5,525,412 (-)NCBI
Rnor_6.0114,175,078 - 4,397,335 (-)NCBI
Rnor_5.0117,871,257 - 8,090,100 (-)NCBI
RGSC_v3.4114,273,771 - 5,330,393 (-)RGD
Celera114,517,639 - 5,495,475 (-)RGD
Sequence:
RefSeq Acc Id: XM_039088451   ⟹   XP_038944379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81117,994,856 - 18,971,895 (-)NCBI
mRatBN7.2114,548,367 - 5,525,420 (-)NCBI
RefSeq Acc Id: XM_039088453   ⟹   XP_038944381
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81117,994,856 - 18,971,895 (-)NCBI
mRatBN7.2114,548,367 - 5,525,420 (-)NCBI
RefSeq Acc Id: XM_039088454   ⟹   XP_038944382
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81117,994,856 - 18,971,894 (-)NCBI
mRatBN7.2114,548,367 - 5,525,420 (-)NCBI
RefSeq Acc Id: XM_039088455   ⟹   XP_038944383
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81117,994,856 - 18,153,563 (-)NCBI
mRatBN7.2114,548,367 - 4,707,055 (-)NCBI
RefSeq Acc Id: XM_039088456   ⟹   XP_038944384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81117,994,856 - 18,154,039 (-)NCBI
mRatBN7.2114,548,367 - 4,707,548 (-)NCBI
RefSeq Acc Id: XM_063270608   ⟹   XP_063126678
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81117,994,856 - 18,153,574 (-)NCBI
RefSeq Acc Id: NP_001040567   ⟸   NM_001047102
- Peptide Label: precursor
- UniProtKB: Q1WIM2 (UniProtKB/Swiss-Prot),   A0A8I6A950 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073563   ⟸   ENSRNOT00000087133
RefSeq Acc Id: ENSRNOP00000040899   ⟸   ENSRNOT00000046370
RefSeq Acc Id: XP_038944381   ⟸   XM_039088453
- Peptide Label: isoform X2
- UniProtKB: Q1WIM2 (UniProtKB/Swiss-Prot),   A0A8I5ZY73 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944382   ⟸   XM_039088454
- Peptide Label: isoform X3
- UniProtKB: Q1WIM2 (UniProtKB/Swiss-Prot),   A0A0A0MY16 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944379   ⟸   XM_039088451
- Peptide Label: isoform X1
- UniProtKB: Q1WIM2 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038944384   ⟸   XM_039088456
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K5U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944383   ⟸   XM_039088455
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K5U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000088030   ⟸   ENSRNOT00000111554
RefSeq Acc Id: ENSRNOP00000093597   ⟸   ENSRNOT00000095471
RefSeq Acc Id: ENSRNOP00000088953   ⟸   ENSRNOT00000099827
RefSeq Acc Id: ENSRNOP00000081968   ⟸   ENSRNOT00000115818
RefSeq Acc Id: ENSRNOP00000082922   ⟸   ENSRNOT00000108768
RefSeq Acc Id: XP_063126678   ⟸   XM_063270608
- Peptide Label: isoform X5
Protein Domains
Ig-like   Ig-like C2-type   Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q1WIM2-F1-model_v2 AlphaFold Q1WIM2 1-435 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305678 AgrOrtholog
BioCyc Gene G2FUF-22296 BioCyc
Ensembl Genes ENSRNOG00000030840 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046370 ENTREZGENE
  ENSRNOT00000046370.6 UniProtKB/TrEMBL
  ENSRNOT00000087133.2 UniProtKB/TrEMBL
  ENSRNOT00000095471.1 UniProtKB/TrEMBL
  ENSRNOT00000099827.1 UniProtKB/TrEMBL
  ENSRNOT00000108768.1 UniProtKB/TrEMBL
  ENSRNOT00000111554 ENTREZGENE
  ENSRNOT00000111554.1 UniProtKB/TrEMBL
  ENSRNOT00000115818.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurexin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:360687 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 360687 ENTREZGENE
PANTHER CELL ADHESION MOLECULE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cadm2 PhenoGen
PIRSF TyrPK_CSF1-R UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000030840 RatGTEx
SMART 4.1m UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A0MY16 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K5U6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZU16_RAT UniProtKB/TrEMBL
  A0A8I5ZY73 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A666_RAT UniProtKB/TrEMBL
  A0A8I6A950 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GKD0_RAT UniProtKB/TrEMBL
  CADM2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Cadm2  cell adhesion molecule 2  Igsf4d_predicted  immunoglobulin superfamily, member 4 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Igsf4d_predicted  immunoglobulin superfamily, member 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED