Mpp7 (MAGUK p55 scaffold protein 7) - Rat Genome Database

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Pathways
Gene: Mpp7 (MAGUK p55 scaffold protein 7) Rattus norvegicus
Analyze
Symbol: Mpp7
Name: MAGUK p55 scaffold protein 7
RGD ID: 1305675
Description: Predicted to enable molecular adaptor activity and protein domain specific binding activity. Predicted to be involved in bicellular tight junction assembly; positive regulation of protein-containing complex assembly; and protein localization to adherens junction. Predicted to be located in adherens junction and bicellular tight junction. Predicted to be part of MPP7-DLG1-LIN7 complex. Predicted to be active in cell-cell junction and plasma membrane. Orthologous to human MPP7 (MAGUK p55 scaffold protein 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC307035; MAGUK p55 subfamily member 7; membrane palmitoylated protein 7; membrane protein, palmitoylated 7; membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81760,135,096 - 60,401,814 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1760,137,701 - 60,401,739 (-)EnsemblGRCr8
mRatBN7.21755,439,939 - 55,706,810 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1755,442,696 - 55,706,748 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1758,609,818 - 58,807,028 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01762,612,908 - 62,810,116 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01756,781,048 - 56,969,444 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01760,057,077 - 60,250,303 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1760,059,949 - 60,250,352 (+)Ensemblrn6Rnor6.0
Rnor_5.01761,830,031 - 62,034,038 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41763,992,348 - 64,282,603 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1756,783,242 - 56,969,313 (-)NCBICelera
RGSC_v3.11764,003,180 - 64,293,387 (-)NCBI
Cytogenetic Map17q12.1NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Alisol A  (EXP)
Alisol B  (EXP)
Alisol C 23-acetate  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
clorgyline  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP,ISO)
Dibutyl phosphate  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
methylmercury chloride  (ISO)
naled  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
sodium arsenite  (EXP,ISO)
sulforaphane  (ISO)
thioacetamide  (EXP)
Triptolide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:17237226   PMID:17332497   PMID:20702775   PMID:25468996  


Genomics

Comparative Map Data
Mpp7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81760,135,096 - 60,401,814 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1760,137,701 - 60,401,739 (-)EnsemblGRCr8
mRatBN7.21755,439,939 - 55,706,810 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1755,442,696 - 55,706,748 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1758,609,818 - 58,807,028 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01762,612,908 - 62,810,116 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01756,781,048 - 56,969,444 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01760,057,077 - 60,250,303 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1760,059,949 - 60,250,352 (+)Ensemblrn6Rnor6.0
Rnor_5.01761,830,031 - 62,034,038 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41763,992,348 - 64,282,603 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1756,783,242 - 56,969,313 (-)NCBICelera
RGSC_v3.11764,003,180 - 64,293,387 (-)NCBI
Cytogenetic Map17q12.1NCBI
MPP7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381028,050,993 - 28,335,203 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1028,050,993 - 28,335,290 (-)Ensemblhg38GRCh38
GRCh371028,339,922 - 28,591,993 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361028,379,928 - 28,611,073 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341028,382,995 - 28,611,021NCBI
Celera1028,103,324 - 28,334,425 (-)NCBICelera
Cytogenetic Map10p12.1NCBI
HuRef1028,057,989 - 28,289,085 (-)NCBIHuRef
CHM1_11028,339,855 - 28,571,010 (-)NCBICHM1_1
T2T-CHM13v2.01028,082,156 - 28,366,353 (-)NCBIT2T-CHM13v2.0
Mpp7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39187,347,962 - 7,627,017 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl187,347,959 - 7,626,866 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38187,347,962 - 7,626,889 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,347,959 - 7,626,866 (-)Ensemblmm10GRCm38
MGSCv37187,347,960 - 7,626,861 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36187,350,735 - 7,626,861 (-)NCBIMGSCv36mm8
Celera187,393,501 - 7,674,355 (-)NCBICelera
Cytogenetic Map18A1NCBI
cM Map184.53NCBI
Mpp7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554621,938,424 - 2,154,507 (-)Ensembl
ChiLan1.0NW_0049554621,933,364 - 2,154,473 (-)NCBIChiLan1.0ChiLan1.0
MPP7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2840,722,400 - 41,006,547 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11040,727,726 - 41,011,874 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01028,202,057 - 28,453,950 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11028,560,675 - 28,812,299 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1028,560,859 - 28,764,212 (-)EnsemblpanPan2panpan1.1
MPP7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1217,793,164 - 18,104,268 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl217,885,581 - 18,101,692 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha24,773,528 - 4,994,243 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0216,043,130 - 16,356,765 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl216,043,100 - 16,356,849 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1215,482,047 - 15,788,491 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0215,368,847 - 15,676,345 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0215,397,180 - 16,078,932 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mpp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093447,821,348 - 8,053,181 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366132,373,879 - 2,540,504 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366132,371,923 - 2,603,746 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPP7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1039,532,370 - 39,798,356 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11039,532,374 - 39,798,357 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21053,000,189 - 53,222,903 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MPP7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1927,622,837 - 27,875,190 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl927,622,672 - 27,827,622 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605133,652,949 - 33,904,383 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mpp7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248056,429,918 - 6,577,479 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248056,430,817 - 6,636,865 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mpp7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11428,543,545 - 28,632,450 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mpp7
2333 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:175
Count of miRNA genes:133
Interacting mature miRNAs:141
Transcripts:ENSRNOT00000025458
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174949693265155015Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)173006647275066472Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)173310464578104645Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)173803135483031354Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172723344583975845Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)173803135483031354Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172328632264246472Rat
1600398Edcs5Endometrial carcinoma susceptibility QTL 52.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)173544694975762341Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)172652205171522051Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172201970567019705Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)173803135483031354Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173803135483031354Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171553702560531414Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)173310464578104645Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172385892668858926Rat
4889891Eae32Experimental allergic encephalomyelitis QTL 324.80.0002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)172723344572233445Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172723344565155015Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172385892668858926Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172385892668858926Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172385892668858926Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)173768787782687877Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172385892668858926Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)174106235286062352Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173219953486201342Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173604553781045537Rat

Markers in Region
D17Rat98  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81760,187,784 - 60,187,971 (+)Marker Load Pipeline
RGSC_v3.41764,047,699 - 64,047,886RGDRGSC3.4
RGSC_v3.41764,047,700 - 64,047,886UniSTSRGSC3.4
Celera1756,831,397 - 56,831,573UniSTS
RGSC_v3.11764,058,533 - 64,058,719RGD
RH 3.4 Map17561.2UniSTS
RH 3.4 Map17561.2RGD
RH 2.0 Map17490.8RGD
SHRSP x BN Map1732.6999RGD
FHH x ACI Map1739.9599RGD
Cytogenetic Map17q12.1UniSTS
D17Rat64  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81760,278,225 - 60,278,355 (+)Marker Load Pipeline
mRatBN7.21755,583,225 - 55,583,355 (-)MAPPERmRatBN7.2
Rnor_6.01760,114,458 - 60,114,587NCBIRnor6.0
Rnor_5.01761,899,202 - 61,899,331UniSTSRnor5.0
RGSC_v3.41764,147,229 - 64,147,359RGDRGSC3.4
RGSC_v3.41764,147,230 - 64,147,359UniSTSRGSC3.4
Celera1756,915,430 - 56,915,559UniSTS
RGSC_v3.11764,158,062 - 64,158,192RGD
FHH x ACI Map1739.9599UniSTS
FHH x ACI Map1739.9599RGD
Cytogenetic Map17q12.1UniSTS
AU047762  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21755,583,195 - 55,583,329 (-)MAPPERmRatBN7.2
Rnor_6.01760,114,484 - 60,114,617NCBIRnor6.0
Rnor_5.01761,899,228 - 61,899,361UniSTSRnor5.0
RGSC_v3.41764,147,200 - 64,147,333UniSTSRGSC3.4
Celera1756,915,400 - 56,915,533UniSTS
Cytogenetic Map17q12.1UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 91 59 6 355 191 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000025458   ⟹   ENSRNOP00000025458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1760,137,701 - 60,332,801 (-)Ensembl
mRatBN7.2 Ensembl1755,442,696 - 55,637,803 (-)Ensembl
Rnor_6.0 Ensembl1760,059,949 - 60,250,352 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101613   ⟹   ENSRNOP00000081208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1760,171,809 - 60,401,739 (-)Ensembl
mRatBN7.2 Ensembl1755,476,797 - 55,706,748 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106864   ⟹   ENSRNOP00000096506
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1760,137,701 - 60,332,801 (-)Ensembl
mRatBN7.2 Ensembl1755,442,696 - 55,637,803 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119790   ⟹   ENSRNOP00000089317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1760,137,701 - 60,288,876 (-)Ensembl
mRatBN7.2 Ensembl1755,442,696 - 55,593,876 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000136237   ⟹   ENSRNOP00000103122
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1760,137,701 - 60,332,801 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000148407   ⟹   ENSRNOP00000099889
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1760,137,701 - 60,332,799 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000163819   ⟹   ENSRNOP00000108147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1760,137,701 - 60,234,626 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000173391   ⟹   ENSRNOP00000108782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1760,137,701 - 60,310,184 (-)Ensembl
RefSeq Acc Id: NM_001100575   ⟹   NP_001094045
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,137,701 - 60,332,801 (-)NCBI
mRatBN7.21755,442,696 - 55,637,803 (-)NCBI
Rnor_6.01760,060,013 - 60,250,107 (+)NCBI
Rnor_5.01761,830,031 - 62,034,038 (+)NCBI
Celera1756,783,242 - 56,969,313 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039095742   ⟹   XP_038951670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,135,096 - 60,401,811 (-)NCBI
mRatBN7.21755,439,939 - 55,706,810 (-)NCBI
RefSeq Acc Id: XM_039095743   ⟹   XP_038951671
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,135,096 - 60,401,814 (-)NCBI
mRatBN7.21755,439,939 - 55,706,810 (-)NCBI
RefSeq Acc Id: XM_063276474   ⟹   XP_063132544
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,135,096 - 60,401,811 (-)NCBI
RefSeq Acc Id: XM_063276475   ⟹   XP_063132545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,195,051 - 60,401,813 (-)NCBI
RefSeq Acc Id: XM_063276476   ⟹   XP_063132546
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,195,060 - 60,401,813 (-)NCBI
RefSeq Acc Id: XM_063276477   ⟹   XP_063132547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81760,195,060 - 60,401,814 (-)NCBI
RefSeq Acc Id: NP_001094045   ⟸   NM_001100575
- UniProtKB: Q5U2Y3 (UniProtKB/Swiss-Prot),   A6KPM5 (UniProtKB/TrEMBL),   A0A8I6ASL7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025458   ⟸   ENSRNOT00000025458
RefSeq Acc Id: XP_038951671   ⟸   XM_039095743
- Peptide Label: isoform X1
- UniProtKB: Q5U2Y3 (UniProtKB/Swiss-Prot),   A6KPM5 (UniProtKB/TrEMBL),   A0A8I6ASL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951670   ⟸   XM_039095742
- Peptide Label: isoform X1
- UniProtKB: Q5U2Y3 (UniProtKB/Swiss-Prot),   A6KPM5 (UniProtKB/TrEMBL),   A0A8I6ASL7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000081208   ⟸   ENSRNOT00000101613
Ensembl Acc Id: ENSRNOP00000089317   ⟸   ENSRNOT00000119790
Ensembl Acc Id: ENSRNOP00000096506   ⟸   ENSRNOT00000106864
RefSeq Acc Id: XP_063132544   ⟸   XM_063276474
- Peptide Label: isoform X1
- UniProtKB: Q5U2Y3 (UniProtKB/Swiss-Prot),   A6KPM5 (UniProtKB/TrEMBL),   A0A8I6ASL7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132545   ⟸   XM_063276475
- Peptide Label: isoform X2
- UniProtKB: A6KPM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132547   ⟸   XM_063276477
- Peptide Label: isoform X3
- UniProtKB: A6KPM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132546   ⟸   XM_063276476
- Peptide Label: isoform X3
- UniProtKB: A6KPM6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000103122   ⟸   ENSRNOT00000136237
Ensembl Acc Id: ENSRNOP00000099889   ⟸   ENSRNOT00000148407
Ensembl Acc Id: ENSRNOP00000108147   ⟸   ENSRNOT00000163819
Ensembl Acc Id: ENSRNOP00000108782   ⟸   ENSRNOT00000173391
Protein Domains
Guanylate kinase-like   L27   PDZ   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2Y3-F1-model_v2 AlphaFold Q5U2Y3 1-576 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305675 AgrOrtholog
BioCyc Gene G2FUF-8965 BioCyc
Ensembl Genes ENSRNOG00000018760 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000025458 ENTREZGENE
  ENSRNOT00000025458.8 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
  L27 domain UniProtKB/Swiss-Prot
  SH3 Domains UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7122468 IMAGE-MGC_LOAD
InterPro GK/Ca_channel_bsu UniProtKB/Swiss-Prot
  Guanylate_kin-like_dom UniProtKB/Swiss-Prot
  Guanylate_kinase_CS UniProtKB/Swiss-Prot
  L27_C UniProtKB/Swiss-Prot
  L27_dom UniProtKB/Swiss-Prot
  L27_dom_sf UniProtKB/Swiss-Prot
  MAGUK UniProtKB/Swiss-Prot
  MPP7_SH3 UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  PDZ_sf UniProtKB/Swiss-Prot
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
KEGG Report rno:307035 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94036 IMAGE-MGC_LOAD
NCBI Gene 307035 ENTREZGENE
PANTHER MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK UniProtKB/Swiss-Prot
Pfam Guanylate_kin UniProtKB/Swiss-Prot
  L27 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  SH3_1 UniProtKB/Swiss-Prot
PhenoGen Mpp7 PhenoGen
PRINTS SH3DOMAIN UniProtKB/Swiss-Prot
PROSITE GUANYLATE_KINASE_1 UniProtKB/Swiss-Prot
  GUANYLATE_KINASE_2 UniProtKB/Swiss-Prot
  L27 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018760 RatGTEx
SMART GuKc UniProtKB/Swiss-Prot
  L27 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF101288 UniProtKB/Swiss-Prot
  SSF50044 UniProtKB/Swiss-Prot
  SSF50156 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I5ZSC6_RAT UniProtKB/TrEMBL
  A0A8I6A9Z1_RAT UniProtKB/TrEMBL
  A0A8I6ASL7 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L2N6_RAT UniProtKB/TrEMBL
  A0ABK0LB19_RAT UniProtKB/TrEMBL
  A0ABK0LDE4_RAT UniProtKB/TrEMBL
  A0ABK0M141_RAT UniProtKB/TrEMBL
  A6KPM5 ENTREZGENE, UniProtKB/TrEMBL
  A6KPM6 ENTREZGENE, UniProtKB/TrEMBL
  MPP7_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-09-23 Mpp7  MAGUK p55 scaffold protein 7  Mpp7  membrane palmitoylated protein 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-04-14 Mpp7  membrane palmitoylated protein 7  Mpp7  membrane protein, palmitoylated 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-20 Mpp7  membrane protein, palmitoylated 7  Mpp7  membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Mpp7  membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)  Mpp7_predicted  membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Mpp7_predicted  membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) (predicted)      Symbol and Name status set to approved 70820 APPROVED