Elovl4 (ELOVL fatty acid elongase 4) - Rat Genome Database

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Gene: Elovl4 (ELOVL fatty acid elongase 4) Rattus norvegicus
Analyze
Symbol: Elovl4
Name: ELOVL fatty acid elongase 4
RGD ID: 1305630
Description: Predicted to enable fatty acid elongase activity. Predicted to be involved in fatty acid biosynthetic process and sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in corneal dystrophy and spinocerebellar ataxia type 34. Orthologous to human ELOVL4 (ELOVL fatty acid elongase 4); PARTICIPATES IN alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4; elongation of very long chain fatty acids protein 4; elongation of very long chain fatty acids-like 4; LOC315851; very long chain fatty acid elongase 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8893,582,930 - 93,609,479 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl893,582,930 - 93,609,678 (-)EnsemblGRCr8
mRatBN7.2884,702,916 - 84,729,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl884,702,362 - 84,729,697 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx890,307,585 - 90,334,102 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0888,532,890 - 88,559,402 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0886,406,017 - 86,432,551 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0891,310,690 - 91,338,625 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl891,310,630 - 91,338,843 (-)Ensemblrn6Rnor6.0
Rnor_5.0890,830,571 - 90,857,120 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4888,855,155 - 88,881,703 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera884,351,953 - 84,378,505 (-)NCBICelera
RGSC_v3.1888,873,228 - 88,901,172 (-)NCBI
Cytogenetic Map8q31NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. The Elovl4 Spinocerebellar Ataxia-34 Mutation 736T>G (p.W246G) Impairs Retinal Function in the Absence of Photoreceptor Degeneration. Agbaga MP, etal., Mol Neurobiol. 2020 Nov;57(11):4735-4753. doi: 10.1007/s12035-020-02052-8. Epub 2020 Aug 11.
2. Diverse macular dystrophy phenotype caused by a novel complex mutation in the ELOVL4 gene. Bernstein PS, etal., Invest Ophthalmol Vis Sci. 2001 Dec;42(13):3331-6.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Synapse-Specific Defects in Synaptic Transmission in the Cerebellum of W246G Mutant ELOVL4 Rats-a Model of Human SCA34. Nagaraja RY, etal., J Neurosci. 2023 Aug 16;43(33):5963-5974. doi: 10.1523/JNEUROSCI.0378-23.2023. Epub 2023 Jul 25.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. Changes in the daily rhythm of lipid metabolism in the diabetic retina. Wang Q, etal., PLoS One. 2014 Apr 15;9(4):e95028. doi: 10.1371/journal.pone.0095028. eCollection 2014.
Additional References at PubMed
PMID:16036915   PMID:18728184   PMID:20937905   PMID:23479632   PMID:34227061  


Genomics

Comparative Map Data
Elovl4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8893,582,930 - 93,609,479 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl893,582,930 - 93,609,678 (-)EnsemblGRCr8
mRatBN7.2884,702,916 - 84,729,466 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl884,702,362 - 84,729,697 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx890,307,585 - 90,334,102 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0888,532,890 - 88,559,402 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0886,406,017 - 86,432,551 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0891,310,690 - 91,338,625 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl891,310,630 - 91,338,843 (-)Ensemblrn6Rnor6.0
Rnor_5.0890,830,571 - 90,857,120 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4888,855,155 - 88,881,703 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera884,351,953 - 84,378,505 (-)NCBICelera
RGSC_v3.1888,873,228 - 88,901,172 (-)NCBI
Cytogenetic Map8q31NCBI
ELOVL4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38679,914,814 - 79,947,553 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl679,914,814 - 79,947,553 (-)Ensemblhg38GRCh38
GRCh37680,624,531 - 80,657,270 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36680,681,248 - 80,713,941 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34680,681,248 - 80,713,941NCBI
Celera681,042,504 - 81,075,295 (-)NCBICelera
Cytogenetic Map6q14.1NCBI
HuRef677,847,380 - 77,880,171 (-)NCBIHuRef
CHM1_1680,722,020 - 80,754,791 (-)NCBICHM1_1
T2T-CHM13v2.0681,123,209 - 81,155,949 (-)NCBIT2T-CHM13v2.0
Elovl4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39983,660,745 - 83,688,358 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl983,660,745 - 83,688,330 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38983,778,692 - 83,806,305 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl983,778,692 - 83,806,277 (-)Ensemblmm10GRCm38
MGSCv37983,672,299 - 83,699,912 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36983,575,410 - 83,602,818 (-)NCBIMGSCv36mm8
Celera980,877,487 - 80,906,281 (-)NCBICelera
Cytogenetic Map9E2NCBI
cM Map945.6NCBI
Elovl4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555027,764,359 - 7,774,572 (-)Ensembl
ChiLan1.0NW_0049555027,764,451 - 7,774,503 (-)NCBIChiLan1.0ChiLan1.0
ELOVL4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25100,002,163 - 100,034,984 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1697,881,486 - 97,914,398 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0677,798,058 - 77,830,840 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1681,068,876 - 81,101,644 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl681,068,882 - 81,102,050 (-)EnsemblpanPan2panpan1.1
ELOVL4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11240,845,357 - 40,876,658 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1240,846,202 - 40,876,758 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1240,717,528 - 40,748,986 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01241,608,796 - 41,640,301 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1241,608,796 - 41,640,369 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11240,922,521 - 40,953,970 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01240,898,942 - 40,930,398 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01241,049,872 - 41,081,359 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Elovl4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494676,194,846 - 76,224,005 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651010,246,356 - 10,276,753 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493651010,246,901 - 10,276,049 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELOVL4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl186,163,868 - 86,195,987 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1186,163,845 - 86,196,036 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2196,867,779 - 96,896,868 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ELOVL4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1134,652,674 - 4,687,308 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl134,652,677 - 4,687,294 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040180,883,243 - 180,916,132 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elovl4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248196,572,161 - 6,602,072 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248196,572,263 - 6,601,991 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Elovl4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1877,914,261 - 77,942,495 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Elovl4
250 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:176
Count of miRNA genes:125
Interacting mature miRNAs:142
Transcripts:ENSRNOT00000012999
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)863141536109261840Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)862848139107848139Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)858337123103337123Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)862848139107848139Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)862970527107970527Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)85076395195763951Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)862848139107848139Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)862848139107848139Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)862848139107848139Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)862848139107848139Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)85158969999045312Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)860248093105248093Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)862848139107848139Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)863404444108404444Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)855428416107963099Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)862963099107963099Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84961020494610204Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)84924517894245178Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)862982864107982864Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)84924517894245178Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
RH131790  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2884,702,581 - 84,702,798 (+)MAPPERmRatBN7.2
Rnor_6.0891,311,742 - 91,311,958NCBIRnor6.0
Rnor_5.0890,830,237 - 90,830,453UniSTSRnor5.0
RGSC_v3.4888,854,821 - 88,855,037UniSTSRGSC3.4
Celera884,351,619 - 84,351,835UniSTS
RH 3.4 Map8978.5UniSTS
Cytogenetic Map8q31UniSTS
AW524708  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2884,701,885 - 84,702,045 (+)MAPPERmRatBN7.2
Rnor_6.0891,311,046 - 91,311,205NCBIRnor6.0
Rnor_5.0890,829,541 - 90,829,700UniSTSRnor5.0
RGSC_v3.4888,854,125 - 88,854,284UniSTSRGSC3.4
Celera884,350,923 - 84,351,082UniSTS
RH 3.4 Map8978.5UniSTS
Cytogenetic Map8q31UniSTS
BF409652  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2884,721,419 - 84,721,513 (+)MAPPERmRatBN7.2
Rnor_6.0891,330,577 - 91,330,670NCBIRnor6.0
Rnor_5.0890,849,072 - 90,849,165UniSTSRnor5.0
RGSC_v3.4888,873,655 - 88,873,748UniSTSRGSC3.4
Celera884,370,455 - 84,370,548UniSTS
RH 3.4 Map8977.7UniSTS
Cytogenetic Map8q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 64 162 67 66 35 71 35 6 284 168 10 141 57 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000012999   ⟹   ENSRNOP00000012999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl893,582,930 - 93,609,678 (-)Ensembl
mRatBN7.2 Ensembl884,702,362 - 84,729,697 (-)Ensembl
Rnor_6.0 Ensembl891,310,630 - 91,338,843 (-)Ensembl
RefSeq Acc Id: NM_001191796   ⟹   NP_001178725
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8893,582,930 - 93,609,479 (-)NCBI
mRatBN7.2884,702,916 - 84,729,466 (-)NCBI
Rnor_6.0891,312,076 - 91,338,625 (-)NCBI
Rnor_5.0890,830,571 - 90,857,120 (-)NCBI
Celera884,351,953 - 84,378,505 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001178725 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77658 (Get FASTA)   NCBI Sequence Viewer  
  EDL77659 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012999
  ENSRNOP00000012999.5
RefSeq Acc Id: NP_001178725   ⟸   NM_001191796
- UniProtKB: D4ACH5 (UniProtKB/TrEMBL),   A6I1R8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012999   ⟸   ENSRNOT00000012999

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ACH5-F1-model_v2 AlphaFold D4ACH5 1-314 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696153
Promoter ID:EPDNEW_R6678
Type:multiple initiation site
Name:Elovl4_1
Description:ELOVL fatty acid elongase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0891,338,858 - 91,338,918EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305630 AgrOrtholog
BioCyc Gene G2FUF-29677 BioCyc
Ensembl Genes ENSRNOG00000009773 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012999 ENTREZGENE
  ENSRNOT00000012999.8 UniProtKB/TrEMBL
InterPro ELO_CS UniProtKB/TrEMBL
  ELOVL4 UniProtKB/TrEMBL
  GNS1_SUR4 UniProtKB/TrEMBL
KEGG Report rno:315851 UniProtKB/TrEMBL
NCBI Gene 315851 ENTREZGENE
PANTHER ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 4 UniProtKB/TrEMBL
  GNS1_SUR4 UniProtKB/TrEMBL
Pfam ELO UniProtKB/TrEMBL
PhenoGen Elovl4 PhenoGen
PROSITE ELO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009773 RatGTEx
UniProt A6I1R8 ENTREZGENE, UniProtKB/TrEMBL
  D4ACH5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Elovl4  ELOVL fatty acid elongase 4  Elovl4  elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Elovl4  elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4   Elovl4_predicted  elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Elovl4_predicted  elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED