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Gene: Fbxl14 (F-box and leucine-rich repeat protein 14) Rattus norvegicus

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Symbol:

Fbxl14

Name:

F-box and leucine-rich repeat protein 14

RGD ID:

1305523

Description:

Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm. Orthologous to human FBXL14 (F-box and leucine rich repeat protein 14); INTERACTS WITH ammonium chloride; bisphenol A; ketoconazole.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

F-box/LRR-repeat protein 14; LOC312675

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	154,334,820 - 154,338,638 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	154,334,092 - 154,377,959 (+)	Ensembl				GRCr8
mRatBN7.2	4	152,662,542 - 152,666,360 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	152,662,542 - 152,666,360 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	158,924,548 - 158,928,366 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	154,708,264 - 154,712,082 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	153,331,612 - 153,335,430 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	151,986,890 - 151,990,706 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	4	219,072,836 - 219,076,652 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	155,824,662 - 155,826,479 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	141,517,575 - 141,521,393 (+)	NCBI		Celera
RGSC_v3.1	4	156,069,826 - 156,072,546 (+)	NCBI
Cytogenetic Map	4	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-palmitoylglycerol (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

crocidolite asbestos (ISO)

dexamethasone (ISO)

diazinon (ISO)

Dibutyl phosphate (ISO)

dorsomorphin (ISO)

entinostat (ISO)

indometacin (ISO)

iron dichloride (ISO)

ketoconazole (EXP)

methoxychlor (EXP)

methylisothiazolinone (ISO)

methylmercury chloride (ISO)

nitrates (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

phenylmercury acetate (ISO)

rotenone (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sunitinib (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

vorinostat (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ubiquitin-dependent protein catabolic process (ISO)

Cellular Component

cytoplasm (IBA,IEA,ISO)

Molecular Function

protein binding (ISO)

ubiquitin-protein transferase activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	GOA pipeline	RGD automated data pipeline
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19028597	PMID:19955572

Genomics

Comparative Map Data

Fbxl14
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	154,334,820 - 154,338,638 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	4	154,334,092 - 154,377,959 (+)	Ensembl				GRCr8
mRatBN7.2	4	152,662,542 - 152,666,360 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	152,662,542 - 152,666,360 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	4	158,924,548 - 158,928,366 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	154,708,264 - 154,712,082 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	153,331,612 - 153,335,430 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	151,986,890 - 151,990,706 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	4	219,072,836 - 219,076,652 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	4	155,824,662 - 155,826,479 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	4	141,517,575 - 141,521,393 (+)	NCBI		Celera
RGSC_v3.1	4	156,069,826 - 156,072,546 (+)	NCBI
Cytogenetic Map	4	q42	NCBI

FBXL14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	1,565,993 - 1,594,842 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	1,565,993 - 1,594,581 (-)	Ensembl			hg38	GRCh38
GRCh37	12	1,675,159 - 1,704,008 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	1,545,420 - 1,573,592 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	1,545,420 - 1,573,592	NCBI
Celera	12	3,282,418 - 3,311,437 (-)	NCBI		Celera
Cytogenetic Map	12	p13.33	NCBI
HuRef	12	1,528,764 - 1,557,372 (-)	NCBI		HuRef
CHM1_1	12	1,674,606 - 1,702,775 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	1,560,304 - 1,591,264 (-)	NCBI		T2T-CHM13v2.0

Fbxl14
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	119,456,629 - 119,460,847 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	119,456,629 - 119,459,591 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	6	119,479,668 - 119,483,886 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	119,479,668 - 119,482,630 (+)	Ensembl			mm10	GRCm38
MGSCv37	6	119,429,686 - 119,433,904 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	6	119,445,398 - 119,448,241 (+)	NCBI		MGSCv36	mm8
Celera	6	121,313,339 - 121,317,557 (+)	NCBI		Celera
Cytogenetic Map	6	F1	NCBI
cM Map	6	56.86	NCBI

Fbxl14
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955454	4,133,718 - 4,137,363 (-)	NCBI	ChiLan1.0	ChiLan1.0

FBXL14
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	7,092,551 - 7,131,288 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	7,098,633 - 7,128,044 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	1,674,046 - 1,703,414 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	1,626,056 - 1,653,656 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	1,626,802 - 1,655,056 (-)	Ensembl			panPan2	panpan1.1

FBXL14
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	43,617,087 - 43,625,269 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	43,618,301 - 43,625,126 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	3,059,620 - 3,067,802 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	43,984,462 - 43,992,650 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	43,985,676 - 43,992,609 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	43,915,558 - 43,923,746 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	43,888,062 - 43,896,238 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	2,417,535 - 2,425,933 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Fbxl14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	107,377,231 - 107,381,495 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936606	1,805,827 - 1,806,870 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936606	1,802,833 - 1,806,870 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FBXL14
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	68,675,531 - 68,678,296 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	68,675,071 - 68,678,219 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	70,936,905 - 70,942,682 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FBXL14
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	1,632,858 - 1,636,225 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666063	6,693,562 - 6,723,982 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fbxl14
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624735	11,273,798 - 11,276,915 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Fbxl14
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	6	27,274,926 - 27,278,248 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Fbxl14
32 total Variants

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
6478754	Anxrr43	Anxiety related response QTL 43		0.14035	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	146370897	184426481	Rat
724558	Plsm2	Polydactyly-luxate syndrome (PLS) morphotypes QTL 2		0.0003	hindlimb integrity trait (VT:0010563)	hind foot phalanges count (CMO:0001949)	4	134095016	179095016	Rat
1582237	Kidm34	Kidney mass QTL 34	4	0.0001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	4	149763204	169799698	Rat
61446	Coreg2	Compensatory renal growth QTL 2	3.5		kidney mass (VT:0002707)	compensatory renal growth score (CMO:0001894)	4	150095743	159267220	Rat
6478693	Anxrr32	Anxiety related response QTL 32		0.00092	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	146370897	184426481	Rat
1358364	Sradr4	Stress Responsive Adrenal Weight QTL 4	4.92		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	131384565	176384565	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	27730518	170099664	Rat
6478763	Anxrr46	Anxiety related response QTL 46		0.07428	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	112427331	157427331	Rat
6478760	Anxrr45	Anxiety related response QTL 45		0.06717	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	112427331	157427331	Rat
61451	Ciaa4	CIA Autoantibody QTL 4	3.1		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	4	123870974	168870974	Rat
1331802	Srn5	Serum renin concentration QTL 5	3.045		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	4	117559384	162559384	Rat
1331738	Bp209	Blood pressure QTL 209	2.979		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	140059299	181024663	Rat
6478700	Anxrr33	Anxiety related response QTL 33		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
1298524	Oia8	Oil induced arthritis QTL 8			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	140059299	184426481	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	60916264	184426481	Rat
7207480	Bss105	Bone structure and strength QTL 105	8.1		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	4	111383604	156383604	Rat
634335	Anxrr16	Anxiety related response QTL 16	7.22		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	94638356	168870820	Rat
737821	Hcar9	Hepatocarcinoma resistance QTL 9	3.7		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	4	106848959	168870974	Rat
7411558	Bw133	Body weight QTL 133	13.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	127263297	172263297	Rat
6478778	Anxrr51	Anxiety related response QTL 51		0.25384	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	126334185	171334185	Rat
10401796	Kidm48	Kidney mass QTL 48			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	147299608	184426481	Rat
6478718	Anxrr34	Anxiety related response QTL 34		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
631511	Pia7	Pristane induced arthritis QTL 7	4.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	123870974	168870974	Rat
1549832	Bss3	Bone structure and strength QTL 3	11		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	4	111383604	156383604	Rat
70177	Xhs1	X-ray hypersensitivity QTL 1	25.1		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	4	82944895	154403548	Rat
634347	Hcar8	Hepatocarcinoma resistance QTL 8	5.8		liver integrity trait (VT:0010547)	liver tumorous lesion area to total liver area ratio (CMO:0001075)	4	124700988	169700988	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	174095838	Rat
1576316	Ept5	Estrogen-induced pituitary tumorigenesis QTL 5	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	4	100752691	179366077	Rat
1581566	Eae21	Experimental allergic encephalomyelitis QTL 21	6.2		body mass (VT:0001259)	maximum body weight loss to initial body weight ratio (CMO:0001400)	4	137447185	182447185	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	45429709	157555683	Rat
1578674	Bmd12	Bone mineral density QTL 12	3.8		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	4	137430611	182430611	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	60916264	184426481	Rat
1358202	Gluco11	Glucose level QTL 11	2.4	0.02	adipocyte glucose uptake trait (VT:0004185)	absolute change in adipocyte glucose uptake (CMO:0000873)	4	86709649	168870974	Rat
61422	Cia13	Collagen induced arthritis QTL 13	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	134199006	168870974	Rat
634342	Cia24	Collagen induced arthritis QTL 24	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	148121375	176967367	Rat
737978	Pia23	Pristane induced arthritis QTL 23	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	123870974	168870974	Rat
61362	Oia2	Oil induced arthritis QTL 2		0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	140059299	184426481	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	65495851	159259805	Rat
12798519	Anxrr54	Anxiety related response QTL 54	2.54	0.05	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	116184844	161184844	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	12212457	182430611	Rat
6478748	Anxrr42	Anxiety related response QTL 42		0.28008	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	146370897	184426481	Rat
12798525	Anxrr57	Anxiety related response QTL 57	3.21	0.05	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	148834094	168870974	Rat

Markers in Region

RH133478

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	152,665,128 - 152,665,308 (+)	MAPPER	mRatBN7.2
mRatBN7.2	8	55,696,821 - 55,697,000 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	59,890,213 - 59,890,391	NCBI	Rnor6.0
Rnor_6.0	4	151,989,475 - 151,989,654	NCBI	Rnor6.0
Rnor_5.0	8	58,471,021 - 58,471,199	UniSTS	Rnor5.0
Rnor_5.0	4	219,075,421 - 219,075,600	UniSTS	Rnor5.0
RGSC_v3.4	4	155,827,384 - 155,827,563	UniSTS	RGSC3.4
RGSC_v3.4	8	58,869,564 - 58,869,742	UniSTS	RGSC3.4
Celera	8	55,181,702 - 55,181,880	UniSTS
Celera	4	141,520,162 - 141,520,341	UniSTS
RH 3.4 Map	8	614.59	UniSTS
Cytogenetic Map	4	q42	UniSTS
Cytogenetic Map	8	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	hemolymphoid system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	sensory system	visual system
7	1	18	52	67	138	95	11	51	36	32	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001271276	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000094505 ⟹ ENSRNOP00000089410

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	154,334,092 - 154,377,959 (+)	Ensembl
mRatBN7.2 Ensembl	4	152,662,542 - 152,666,360 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000137009 ⟹ ENSRNOP00000107185

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	4	154,334,810 - 154,338,589 (+)	Ensembl

RefSeq Acc Id:

NM_001271276 ⟹ NP_001258205

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	154,334,820 - 154,338,638 (+)	NCBI
mRatBN7.2	4	152,662,542 - 152,666,360 (+)	NCBI
Rnor_6.0	4	151,986,890 - 151,990,706 (+)	NCBI
Rnor_5.0	4	219,072,836 - 219,076,652 (+)	NCBI
Celera	4	141,517,575 - 141,521,393 (+)	NCBI

Sequence:

show sequence

GCTGCCGCGCGGGGGCGGGAAGGGAGGCAGGAAGGAAGCGCCGCTCGGACGCTCCGGGAGGAGG
AGCGGCGGCCCGGCCGGAAGGCGGGGAGGGGCGCCGTTGGCCCGCGGCGGCCCGCTCTCGGCGC
CTCACCGGGGCGGCGGCGCCCGCGCCTCCTGCACCCGGCGCGGCGTAGCGGCGGGAGGAAGATG
GAGACCCACATCTCGTGCCTGTTTCCGGAGCTGCTGGCCATGATCTTCGGCTACTTGGACGTCC
GAGACAAGGGTCGCGCGGCGCAGGTGTGCACGGCCTGGCGGGACGCCGCCTACCACAAGTCAGT
GTGGCGGGGCGTGGAGGCCAAGCTGCACCTGCGCCGGGCGAACCCGTCGCTGTTCCCCAGCCTT
CAGGCCCGGGGCATCCGCCGCGTGCAGATCCTCAGCCTCCGCCGCAGCCTCAGCTACGTGATCC
AGGGCATGGCGAACATCGAGAGCCTCAACCTCAGCGGCTGCTACAACCTCACCGATAACGGCCT
GGGCCACGCGTTCGTGCAGGAGATCGGCTCGCTGCGCGCTCTCAACTTGAGCCTCTGCAAGCAG
ATCACAGACAGCAGCCTGGGCCGCATAGCCCAGTACCTCAAGGGCCTGGAGGTGCTAGAGCTGG
GGGGCTGCAGCAACATCACCAACACCGGCCTTCTGCTCATCGCCTGGGGGCTGCAGCGCCTCAA
GAGCCTTAACCTCCGCAGCTGCCGCCATCTCTCAGACGTGGGCATCGGGCACCTGGCCGGCATG
ACGCGCAGCGCTGCCGAGGGCTGCCTGGGCCTGGAGCAGCTCACTCTACAGGACTGCCAGAAAC
TCACGGATCTTTCTCTGAAGCACATCTCGCGAGGGCTGACGGGCCTCAGGCTCCTCAACCTCAG
CTTCTGTGGCGGGATCTCGGACGCGGGCCTTCTGCACCTGTCGCACATGGGCAGCCTGCGCAGC
CTTAACCTGCGCTCCTGCGACAACATCAGCGACACTGGCATCATGCATTTGGCCATGGGCAGCC
TGCGCCTCTCCGGTCTGGATGTGTCATTCTGTGACAAGGTGGGAGATCAGAGCCTGGCTTACAT
AGCCCAGGGACTGGACGGCCTCAAGTCCCTCTCCCTTTGCTCTTGCCATATCAGTGACGATGGC
ATCAACCGCATGGTGCGGCAGATGCACGGGCTGCGCACGCTCAACATTGGACAGTGTGTGCGCA
TCACGGACAAGGGACTGGAGCTGATCGCTGAGCACCTGAGCCAGCTCACAGGCATAGACCTGTA
CGGCTGCACTAGGATCACCAAGCGCGGCCTGGAGCGCATCACGCAGCTGCCCTGCCTCAAGGTA
CTTAACCTGGGACTTTGGCAGATGACGGACAGTGAGAAGGTCAGGTGAGGGCGGCAGTTCCAGT
TACCCTGCCCCGCCCTGTTCATCCCAGGACCACCACTGTTCCCGCACCCTCACGCGCGCACTTA
CACATTCAGGGCAGTGGCCGCGATGGGGCGATGACGCGAAGCCTGGGCTCTTTTCTCCTAGTCT
GGCGCCCCTCCCCACTGCGTCTGGGGTTCTTCTGCTCCCTCTACCCACTCTCCTCTCCTTTCGC
AGTGAGTGGAGAGATGGACCCTGCTGCTTCTCTGCCCACTCTTCTGCAGGGTGTGGAGACTTTC
AGCCACCGCCAACTGTATCCTGGGGCACTGCATTTGGAAATGGGGTGGGGGCGGGGAGGGACTA
GTTTCAACCCCGAGGAGTTGAGGAAAGATGTCTGCCTTCACGTATACTTTCATTTGGATACTGT
GATCTGGCTTTTATTTCGAAATGTGTAGAAAGCAAGCCCGACTAAAGCAGCCTTTTCATCCACA
TTGTAGCCAGTCTCCTCTCATCGCTGCCCTTCGGTGTCTGCGACTCACTTCGGTTTTGGTTTTG
TTCTTGTTCTTTTTTGGTTTTGTTTTTTTATCTGCTTTCCTTTTAATTTTCAAAGAATTTGAAA
TCATTGTCCTTTTTTTCTGCTGAGTATATTCTATATATTCTATATATATATGTGTCCTATATAT
ATGTGTCTGGCTACCTCGTTTTAGTTTACTTTTTTCTCTTAAGCCCTGGAATTCTACAAGAGAG
ATATTTTGAGATTGAAACATTTTTGTGCCTAGACTGGAAAGATGCCCACTGGGTTTGTATCTGT
TTTTGGTTTTGACTTCTTCCTAACCTCCCTCTGCCCAGTGTGTTCACTTCCGCATCCTGGCTAT
GACTTTACCCCTTGTATTGGGTTTTGATGACCCAACCTTGTTTCTAAAGATTGACTTAATTTAT
AGCACAAATGTATGGGAGGAATGAGAGCAGAACTTCCTTTTCGTTTGTTTGAGATGCAGATTGA
GTCTTGAAGAGGAAGGAGTATTATATATGCAAATGACGTCCCAATCCCACCCCTCTTCCAAGCC
TTCCCACCAGAAGGTTACAGTGAGGCTTCCAGCCCTGTCTAGGAGCTCAGAGTCTGCAGAGAGC
CCGAGGCTATGTGAAAGGGAGGAGACTGAACTTCATGTCTTATCTGTGTTCTGTTCATGAAATG
GGAGGAACGTGTGAGTTTGAAAAACTTTTGTTTCTAAATGGAGGAATAGATGACTTTATTTTGG
TGGGGGGTTGGGACTGTGGCTTTAAAACAAATGGCTTTTGAGTAGGATGTATATTTTTGTTGGA
TATTTTGTTTGTTTATTTTTTTAGAGTCCTCCACAGCAACATGAGAGACCATGGAGAAACCCAG
AGACCTTTATCAATTAATTGTACTGTTTGTGAATTTGTATAAATGATAACAAAGATCCTCTTAA
AACGTTTATATTCTTACAGTAAAAGGTTAAACCGATATTTATATAATAAAAGAGGAAATATGAA
GTATGTTTTTGAAAAAAAAAAGCACAAAATCCCCCCCTTGTATCTGTGAATTATTTTTAAGGCA
TTGTGTGTTGGGTACGTGCTCAGGTGGGAGGTGTTATGTGTGCATGGAAACTGGAAGGAAGGTA
GAGTTCAGTTTGCTCATGCGGTGTAAGTTCATGATTGAGAATTTCTTCTGTGTAAGATTTACCA
CTGACATCCAAATGTTCTGTCTCTAGAAATGTGATCAGACTGGAGAGTTCTATAAATTTTGGTT
TTAAACTGTCAACATGGAAACCGAAAGAAAATGAAGAAAATGAAACTTTTTTTTTTTTTTTTTT
TTTTAAGAAACCAGACTTGGAAGAGTCAGTTTCCCATAGTGGCCAGTTTCTTCTGGGGAATGGT
GGTGGTGGAGGTGAAACCCAGGGGTAATCGGGAGGAAGTGGGTCCTGAACTCTGGAAGTGGTCA
ATAGGGTGGGCATCCTTACACTGGGAGCTTGTGTGGGATGGAGGGGACCAGCCATTGTTCTGGG
GAAGTTGAAAGTGTTCTCCTAGCTGGCTGGCCTAGTCCCGCATGCTCCTGTTGTGCAGGTCCAT
CGGAAGGGGGCAGCAGTGCTCTTTAACATTTCCCTTCAGGCCTGGCTGCAGGCAGACCCTCTGC
TGGGGCTTAGGGAGACTGGTTAGAAGTTTAGGCACATTTTCGCTTTAAGCCCTTCTAGTACCCA
GGCTGGCCACTCAGCCATTGGTGGGGGTCTAGGCTGAATTCAGGGCAGACAGGGGAATACTAAC
AATTTTAGCACAGTTCTCCTGAGTAGACAGGCAGTAGTGTGACTTCTGTAGGCTGAGGGATGGA
GACTGCGCTCACCCTGGGAGTGAGCCACAGCCCTGACTTCACATAGGTGGGCTTTGTTTCTGAG
ATCAACCCATTAAGATGGCTGGTTCCTAGATCATCCCATCATT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001258205	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM02056	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000089410
	ENSRNOP00000089410.1
	ENSRNOP00000107185.1

RefSeq Acc Id:

NP_001258205 ⟸ NM_001271276

- UniProtKB:

A0A8I6GI29 (UniProtKB/TrEMBL), A6IL86 (UniProtKB/TrEMBL)

- Sequence:

show sequence

METHISCLFPELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPS
LQARGIRRVQILSLRRSLSYVIQGMANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCK
QITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAG
MTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLR
SLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSCHISDD
GINRMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQLPCLK
VLNLGLWQMTDSEKVR

hide sequence

Ensembl Acc Id:

ENSRNOP00000089410 ⟸ ENSRNOT00000094505

Ensembl Acc Id:

ENSRNOP00000107185 ⟸ ENSRNOT00000137009

Protein Domains

F-box

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305523	AgrOrtholog
BioCyc Gene	G2FUF-43217	BioCyc
Ensembl Genes	ENSRNOG00000070828	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000094505	ENTREZGENE
	ENSRNOT00000094505.2	UniProtKB/TrEMBL
	ENSRNOT00000137009.1	UniProtKB/TrEMBL
Gene3D-CATH	3.80.10.10	UniProtKB/TrEMBL
InterPro	F-box-like_dom_sf	UniProtKB/TrEMBL
	F-box_dom	UniProtKB/TrEMBL
	FBXL14_F-box	UniProtKB/TrEMBL
	Leu-rich_rpt	UniProtKB/TrEMBL
	Leu-rich_rpt_Cys-con_subtyp	UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:312675	UniProtKB/TrEMBL
NCBI Gene	312675	ENTREZGENE
PANTHER	UNCHARACTERIZED	UniProtKB/TrEMBL
Pfam	F-box-like	UniProtKB/TrEMBL
	LRR_6	UniProtKB/TrEMBL
PhenoGen	Fbxl14	PhenoGen
RatGTEx	ENSRNOG00000070828	RatGTEx
SMART	LRR_CC	UniProtKB/TrEMBL
Superfamily-SCOP	RNI-like	UniProtKB/TrEMBL
	SSF81383	UniProtKB/TrEMBL
UniProt	A0A8I6GI29	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L9R6_RAT	UniProtKB/TrEMBL
	A6IL86	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Fbxl14	F-box and leucine-rich repeat protein 14	Fbxl14_predicted	F-box and leucine-rich repeat protein 14 (predicted)	'predicted' is removed	2292626	APPROVED
2008-01-09	Fbxl14_predicted	F-box and leucine-rich repeat protein 14 (predicted)	LOC681623	similar to F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14)	Data merged from RGD:1592908	1643240	APPROVED
2006-11-20	LOC681623	similar to F-box/LRR-repeat protein 14 (F-box and leucine-rich repeat protein 14)			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-01-12	Fbxl14_predicted	F-box and leucine-rich repeat protein 14 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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