Rnf2 (ring finger protein 2) - Rat Genome Database

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Gene: Rnf2 (ring finger protein 2) Rattus norvegicus
Analyze
Symbol: Rnf2
Name: ring finger protein 2
RGD ID: 1305491
Description: Predicted to enable several functions, including RING-like zinc finger domain binding activity; histone H2AK119 ubiquitin ligase activity; and zinc ion binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Involved in response to retinoic acid and spinal cord development. Predicted to be located in nuclear body. Predicted to be part of chromatin and nucleus. Predicted to be active in cytoplasm and nucleus. Biomarker of spina bifida. Human ortholog(s) of this gene implicated in Luo-Schoch-Yamamoto syndrome. Orthologous to human RNF2 (ring finger protein 2); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,4-dinitrotoluene; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase RING2; LOC304850; MGC114502; RING finger protein 1B; RING-type E3 ubiquitin transferase RING2; RING1b
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81366,103,943 - 66,136,038 (-)NCBIGRCr8
mRatBN7.21363,553,964 - 63,584,047 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1363,554,862 - 63,583,099 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1366,173,599 - 66,202,587 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01367,438,219 - 67,467,208 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01364,701,587 - 64,730,534 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01368,829,714 - 68,859,920 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1368,830,620 - 68,858,809 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01373,791,946 - 73,821,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41366,345,663 - 66,373,826 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11366,359,742 - 66,387,906 (-)NCBI
Celera1363,485,726 - 63,513,888 (-)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO,ISS)
euchromatin  (IEA,ISO)
heterochromatin  (ISO)
MLL1 complex  (IEA,ISO,ISS)
nuclear body  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (ISO,ISS)
PcG protein complex  (IBA,IEA,ISO,ISS)
PRC1 complex  (IEA,ISO,ISS)
sex chromatin  (IEA,ISO)
ubiquitin ligase complex  (IBA,IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. PRC1 complex diversity: where is it taking us? Gil J and O'Loghlen A, Trends Cell Biol. 2014 Jul 22. pii: S0962-8924(14)00102-0. doi: 10.1016/j.tcb.2014.06.005.
3. The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma. Martinez-Romero C, etal., J Pathol. 2009 Oct;219(2):205-13. doi: 10.1002/path.2585.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Simon JA and Kingston RE, Mol Cell. 2013 Mar 7;49(5):808-24. doi: 10.1016/j.molcel.2013.02.013.
10. Retinal proteomic changes under different ischemic conditions - implication of an epigenetic regulatory mechanism. Stowell C, etal., Int J Physiol Pathophysiol Pharmacol. 2010 Jun 30;2(2):148-160.
11. Polycomb group proteins are essential for spinal cord development. Wang C, etal., Front Biosci (Landmark Ed). 2010 Jun 1;15:1018-22.
Additional References at PubMed
PMID:12167701   PMID:12183370   PMID:12477932   PMID:12589020   PMID:14557078   PMID:15489334   PMID:15525528   PMID:15741318   PMID:15960975   PMID:16359901   PMID:16624538   PMID:16687444  
PMID:16714294   PMID:16943429   PMID:18311137   PMID:18629613   PMID:19636380   PMID:21282530   PMID:22770845   PMID:23027973   PMID:23486062   PMID:24034696   PMID:25519132   PMID:28596365  
PMID:30361391  


Genomics

Comparative Map Data
Rnf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81366,103,943 - 66,136,038 (-)NCBIGRCr8
mRatBN7.21363,553,964 - 63,584,047 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1363,554,862 - 63,583,099 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1366,173,599 - 66,202,587 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01367,438,219 - 67,467,208 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01364,701,587 - 64,730,534 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01368,829,714 - 68,859,920 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1368,830,620 - 68,858,809 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01373,791,946 - 73,821,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41366,345,663 - 66,373,826 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11366,359,742 - 66,387,906 (-)NCBI
Celera1363,485,726 - 63,513,888 (-)NCBICelera
Cytogenetic Map13q21NCBI
RNF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381185,045,558 - 185,102,603 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1185,045,526 - 185,102,603 (+)EnsemblGRCh38hg38GRCh38
GRCh371185,014,690 - 185,071,735 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361183,281,174 - 183,338,363 (+)NCBINCBI36Build 36hg18NCBI36
Build 341181,746,207 - 181,803,397NCBI
Celera1158,125,254 - 158,182,437 (+)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1156,249,794 - 156,306,846 (+)NCBIHuRef
CHM1_11186,434,264 - 186,493,430 (+)NCBICHM1_1
T2T-CHM13v2.01184,402,444 - 184,459,513 (+)NCBIT2T-CHM13v2.0
Rnf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391151,345,159 - 151,376,562 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1151,333,755 - 151,376,706 (-)EnsemblGRCm39 Ensembl
GRCm381151,469,398 - 151,500,991 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1151,458,004 - 151,500,955 (-)EnsemblGRCm38mm10GRCm38
MGSCv371153,316,536 - 153,347,953 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361153,231,624 - 153,263,041 (-)NCBIMGSCv36mm8
Celera1153,898,457 - 153,929,917 (-)NCBICelera
Cytogenetic Map1G1NCBI
cM Map164.15NCBI
Rnf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540623,672,947 - 23,725,253 (+)NCBIChiLan1.0ChiLan1.0
RNF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2164,620,643 - 64,679,042 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,304,249 - 64,362,614 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01160,568,438 - 160,626,783 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11164,721,554 - 164,779,420 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,721,458 - 164,779,420 (+)Ensemblpanpan1.1panPan2
RNF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1718,240,672 - 18,283,091 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl718,236,115 - 18,281,387 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha717,818,956 - 17,868,157 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0717,967,438 - 18,016,584 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl717,967,947 - 18,014,756 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1717,876,830 - 17,926,016 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0717,984,666 - 18,033,949 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0718,115,806 - 18,164,938 (+)NCBIUU_Cfam_GSD_1.0
Rnf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934487,222,673 - 87,263,262 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364815,070,578 - 5,110,068 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364815,070,578 - 5,110,087 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9126,172,301 - 126,287,603 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19126,172,637 - 126,284,567 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29138,670,468 - 138,730,404 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12544,289,662 - 44,345,168 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2544,291,576 - 44,345,236 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605545,500,165 - 45,555,796 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248148,470,818 - 8,516,252 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rnf2
100 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:123
Count of miRNA genes:105
Interacting mature miRNAs:112
Transcripts:ENSRNOT00000065944
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132369296968692969Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132369296968692969Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132320344868203448Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)135949252277046890Rat
2303028Bp329Blood pressure QTL 329arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135849787273485113Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133228447177284471Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat

Markers in Region
RH129133  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21363,554,895 - 63,555,075 (+)MAPPERmRatBN7.2
Rnor_6.01368,830,646 - 68,830,825NCBIRnor6.0
Rnor_5.01373,792,878 - 73,793,057UniSTSRnor5.0
RGSC_v3.41366,345,690 - 66,345,869UniSTSRGSC3.4
Celera1363,485,753 - 63,485,932UniSTS
RH 3.4 Map13221.4UniSTS
Cytogenetic Map13q21UniSTS
RH143600  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21363,554,588 - 63,554,872 (+)MAPPERmRatBN7.2
Rnor_6.01368,830,339 - 68,830,622NCBIRnor6.0
Rnor_5.01373,792,571 - 73,792,854UniSTSRnor5.0
RGSC_v3.41366,345,383 - 66,345,666UniSTSRGSC3.4
Celera1363,485,446 - 63,485,729UniSTS
RH 3.4 Map13300.4UniSTS
Cytogenetic Map13q21UniSTS
AW533161  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21363,555,387 - 63,555,562 (+)MAPPERmRatBN7.2
Rnor_6.01368,831,138 - 68,831,312NCBIRnor6.0
Rnor_5.01373,793,370 - 73,793,544UniSTSRnor5.0
RGSC_v3.41366,346,182 - 66,346,356UniSTSRGSC3.4
Celera1363,486,245 - 63,486,419UniSTS
RH 3.4 Map13221.1UniSTS
Cytogenetic Map13q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 41 55 39 19 39 8 11 74 35 41 11 8
Low 2 2 2 2
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000065944   ⟹   ENSRNOP00000061975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1363,554,870 - 63,583,035 (-)Ensembl
Rnor_6.0 Ensembl1368,830,620 - 68,858,781 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092053   ⟹   ENSRNOP00000068794
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1363,554,863 - 63,583,054 (-)Ensembl
Rnor_6.0 Ensembl1368,831,371 - 68,858,809 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095575   ⟹   ENSRNOP00000094293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1363,554,863 - 63,583,054 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100223   ⟹   ENSRNOP00000097279
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1363,554,862 - 63,583,099 (-)Ensembl
RefSeq Acc Id: NM_001401380   ⟹   NP_001388309
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81366,103,943 - 66,132,911 (-)NCBI
mRatBN7.21363,553,964 - 63,582,933 (-)NCBI
RefSeq Acc Id: XM_063272315   ⟹   XP_063128385
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81366,104,034 - 66,136,038 (-)NCBI
RefSeq Acc Id: ENSRNOP00000068794   ⟸   ENSRNOT00000092053
RefSeq Acc Id: ENSRNOP00000061975   ⟸   ENSRNOT00000065944
RefSeq Acc Id: ENSRNOP00000097279   ⟸   ENSRNOT00000100223
RefSeq Acc Id: ENSRNOP00000094293   ⟸   ENSRNOT00000095575
RefSeq Acc Id: NP_001388309   ⟸   NM_001401380
- UniProtKB: Q4KLY4 (UniProtKB/Swiss-Prot),   A0A0G2JTP7 (UniProtKB/TrEMBL),   A6ICS7 (UniProtKB/TrEMBL),   M5AJY0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128385   ⟸   XM_063272315
- Peptide Label: isoform X1
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KLY4-F1-model_v2 AlphaFold Q4KLY4 1-308 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698885
Promoter ID:EPDNEW_R9410
Type:multiple initiation site
Name:Rnf2_1
Description:ring finger protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01368,858,669 - 68,858,729EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305491 AgrOrtholog
BioCyc Gene G2FUF-17930 BioCyc
Ensembl Genes ENSRNOG00000002454 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000065944.3 UniProtKB/Swiss-Prot
  ENSRNOT00000092053 ENTREZGENE
  ENSRNOT00000092053.2 UniProtKB/TrEMBL
  ENSRNOT00000095575.1 UniProtKB/TrEMBL
  ENSRNOT00000100223.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7456372 IMAGE-MGC_LOAD
InterPro RAWUL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING1/RING2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING2 UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:114502 IMAGE-MGC_LOAD
NCBI Gene 304850 ENTREZGENE
PANTHER PTHR46076 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR46076:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RAWUL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C3HC4_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rnf2 PhenoGen
PROSITE ZF_RING_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002454 RatGTEx
SMART RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JTP7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AQI2_RAT UniProtKB/TrEMBL
  A0A8I6GLZ9_RAT UniProtKB/TrEMBL
  A6ICS7 ENTREZGENE, UniProtKB/TrEMBL
  M5AJY0 ENTREZGENE, UniProtKB/TrEMBL
  Q4KLY4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Rnf2  ring finger protein 2  Rnf2_predicted  ring finger protein 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Rnf2_predicted  ring finger protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED