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Gene: Siglec5 (sialic acid binding Ig-like lectin 5) Rattus norvegicus

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Symbol:

Siglec5

Name:

sialic acid binding Ig-like lectin 5

RGD ID:

1305432

Description:

Predicted to enable sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including SIGLEC5 (sialic acid binding Ig like lectin 5); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC292843; sialic acid-binding Ig-like lectin 5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SIGLEC6 (sialic acid binding Ig like lectin 6)	HGNC	Ensembl, OMA, Panther
Pan paniscus (bonobo/pygmy chimpanzee):	SIGLEC6 (sialic acid binding Ig like lectin 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LOC100515551 (sialic acid-binding Ig-like lectin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SIGLEC6 (sialic acid binding Ig like lectin 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SIGLEC14 (sialic acid binding Ig like lectin 14)	HGNC	Inparanoid, OrthoDB
Homo sapiens (human):	CD33 (CD33 molecule)	HGNC	Ensembl, Panther
Homo sapiens (human):	SIGLEC5 (sialic acid binding Ig like lectin 5)	HGNC	EggNOG, OrthoDB
Homo sapiens (human):	SIGLEC8 (sialic acid binding Ig like lectin 8)	HGNC	HomoloGene
Homo sapiens (human):	ZNF205 (zinc finger protein 205)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	SIGLEC5 (sialic acid binding Ig like lectin 5)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Mus musculus (house mouse):	Siglecf (sialic acid binding Ig-like lectin F)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SIGLEC6 (sialic acid binding Ig like lectin 6)	Alliance	DIOPT (HGNC\|OrthoFinder\|PANTHER)
Homo sapiens (human):	SIGLEC14 (sialic acid binding Ig like lectin 14)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Homo sapiens (human):	SIGLEC14 (sialic acid binding Ig like lectin 14)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|SonicParanoid)
Danio rerio (zebrafish):	bckdhbl (branched chain keto acid dehydrogenase E1, beta polypeptide, like)	Alliance	DIOPT (Ensembl Compara\|PANTHER)
Danio rerio (zebrafish):	zmp:0000000650	Alliance	DIOPT (OMA\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	zmp:0000000650	Alliance	DIOPT (PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-24p1.7	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	si:dkey-24p1.7	Alliance	DIOPT (Hieranoid\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	siglecl1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	siglecl1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	XB5961956 [provisional]	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	XB5961956 [provisional]	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	u2af2	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	siglecl2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC105947862	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC105947864	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC108648058	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC116412390	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC100493517	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC101732718	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC116412391	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC101733090	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC101730610	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC101731998	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC116412389	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC100486156	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	102,904,705 - 102,913,281 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	102,904,578 - 102,913,281 (+)	Ensembl				GRCr8
mRatBN7.2	1	93,768,190 - 93,776,696 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	93,768,319 - 93,776,694 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	99,153,070 - 99,161,477 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	107,625,742 - 107,634,147 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	100,918,316 - 100,926,723 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	98,562,351 - 98,570,992 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	98,562,346 - 98,570,949 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	99,630,691 - 99,647,749 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	93,734,855 - 93,743,230 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	88,044,977 - 88,053,352 (+)	NCBI		Celera
RGSC_v3.1	1	93,812,767 - 93,820,654 (+)	NCBI
Cytogenetic Map	1	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

prostate cancer (ISO)

systemic lupus erythematosus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-diaminodiphenylmethane (EXP)

acetamide (EXP)

arsenous acid (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

bromobenzene (EXP)

butanal (ISO)

cadmium dichloride (EXP)

cefaloridine (EXP)

Cuprizon (EXP)

diarsenic trioxide (ISO)

dioxygen (EXP)

ethylparaben (ISO)

folic acid (ISO)

fulvestrant (ISO)

lead diacetate (EXP)

methcathinone (ISO)

nickel atom (ISO)

nitrofen (EXP)

oxaliplatin (EXP)

pentanal (ISO)

phorbol 13-acetate 12-myristate (ISO)

silver atom (ISO)

silver(0) (ISO)

sulforaphane (ISO)

testosterone (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (EXP)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (IBA,IEA)

negative regulation of inflammatory response (IEA)

Cellular Component

membrane (IEA)

plasma membrane (IBA)

Molecular Function

carbohydrate binding (IEA)

protein binding (ISO)

sialic acid binding (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15048729	PMID:17562860

Genomics

Comparative Map Data

Siglec5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	102,904,705 - 102,913,281 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	102,904,578 - 102,913,281 (+)	Ensembl				GRCr8
mRatBN7.2	1	93,768,190 - 93,776,696 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	93,768,319 - 93,776,694 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	99,153,070 - 99,161,477 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	107,625,742 - 107,634,147 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	100,918,316 - 100,926,723 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	98,562,351 - 98,570,992 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	98,562,346 - 98,570,949 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	99,630,691 - 99,647,749 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	93,734,855 - 93,743,230 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	88,044,977 - 88,053,352 (+)	NCBI		Celera
RGSC_v3.1	1	93,812,767 - 93,820,654 (+)	NCBI
Cytogenetic Map	1	q22	NCBI

SIGLEC6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	51,517,819 - 51,531,670 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	51,517,819 - 51,531,856 (-)	Ensembl			hg38	GRCh38
GRCh37	19	52,021,073 - 52,034,924 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	56,714,795 - 56,726,876 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	19	56,712,885 - 56,726,876	NCBI
Celera	19	49,073,824 - 49,086,158 (-)	NCBI		Celera
Cytogenetic Map	19	q13.41	NCBI
HuRef	19	48,355,242 - 48,367,576 (-)	NCBI		HuRef
CHM1_1	19	52,024,687 - 52,037,026 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	54,606,444 - 54,620,306 (-)	NCBI		T2T-CHM13v2.0

SIGLEC6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	57,564,377 - 57,576,683 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	59,482,480 - 59,498,134 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	48,459,184 - 48,474,451 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	57,344,937 - 57,358,982 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

LOC100515551
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	6	55,781,438 - 55,791,954 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	51,581,366 - 51,600,587 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SIGLEC6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	44,367,499 - 44,405,288 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	44,367,624 - 44,382,790 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666073	24,420,299 - 24,457,079 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Siglec5
157 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	306
Count of miRNA genes:	208
Interacting mature miRNAs:	234
Transcripts:	ENSRNOT00000033648
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	87889942	132889942	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	102780511	182384005	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
2300324	Fetw1	Fetal weight QTL 1	12.1	0.005	fetal growth trait (VT:0004201)	fetal body weight (CMO:0002080)	1	92963855	109494029	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	101228864	146228864	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	87785026	142582336	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	84107164	115183752	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	91302413	136302413	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	102359314	153680016	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	99645382	182701046	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	58769992	103769992	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)	1	92683681	137683681	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	86993904	131993904	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	87558587	132558587	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	92683681	137683681	Rat
737977	Bp160	Blood pressure QTL 160		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	97582336	142582336	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	101594089	146594089	Rat
61433	Cia2	Collagen induced arthritis QTL 2	5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	100345976	145345976	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	96717367	160111531	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	159	91	90	59	91	59	6	349	191	11	136	75	90	31	11	11

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106249	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001437438	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228946	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759327	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227492	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000033648 ⟹ ENSRNOP00000034882

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	102,904,906 - 102,913,281 (+)	Ensembl
mRatBN7.2 Ensembl	1	93,768,319 - 93,776,694 (+)	Ensembl
Rnor_6.0 Ensembl	1	98,562,346 - 98,570,949 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106528 ⟹ ENSRNOP00000088341

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	102,904,906 - 102,913,281 (+)	Ensembl
mRatBN7.2 Ensembl	1	93,768,319 - 93,776,694 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000171344 ⟹ ENSRNOP00000111595

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	102,904,578 - 102,913,281 (+)	Ensembl

RefSeq Acc Id:

NM_001106249 ⟹ NP_001099719

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	102,904,906 - 102,913,281 (+)	NCBI
mRatBN7.2	1	93,768,319 - 93,776,694 (+)	NCBI
Rnor_6.0	1	98,562,351 - 98,570,726 (-)	NCBI
Rnor_5.0	1	99,630,691 - 99,647,749 (-)	NCBI
RGSC_v3.4	1	93,734,855 - 93,743,230 (+)	RGD
Celera	1	88,044,977 - 88,053,352 (+)	RGD

Sequence:

show sequence

CAGTCCTGTGACATTGAAGCCTATGACCCTCGAACTGACCAAGTTTTCTGTCTCTGGAGCCTAG
GACCTTTCACTGCGTGATGCTGTGGGCACAGCTGCTGCCCCTGCTGTGGGCAGGGTCCCTGGCC
GTGGAGAATTATGAGCTCTCATTGACTGAATCAGTGACGGTGCAGGAGGGTCTGTGCGTCTTTG
TACCCTGCCAAGTCAAGTACCCTGCTTCCGGGGGTTCTGTTTTTGGCTACTGGTTCCAGGATGG
GGCCAACACAAACCTCAACTCTCCAGTGGCTACAAATGACCCACATCGACCAGTACAGCAGGAA
ACTCAAGGTCGTTTCTATCTCGTGGGGGGCATAGATACTAAAAATTGCTCCCTGGACATCAGAG
ACGCACGGAAAAGTGACACAGGAAAGTACTTCTTCAGGTTGGATGGAAGTGTGAAATACAGTTT
CCGGAATCGGATGCTCTCTGTGCATGTGACAGCTCTGACTAAGACCCCTAACCTCCAAGTCACA
TCTACCCTGGTGTCTGGCACTTCTACCCGAGTGATCTGTTCTGTGCTCTGGGCCTGTGAGCAGG
GGACACCCCCCATCTTTTCCTGGATGTCATCTGCCCTCACTTCCCTGGGCCGCAGAACCATCCT
CTCCTCAGAGCTGAACCTCACACCTAGGCCTCAGGACAACGGCACCAACCTCATCTGTCAGGTG
ACCTTCCCTGGTGCTGGTGTTACTGTGGAGAGGACTCAACAGCTCAGTGTCACCTATGCTCCAC
AGAAGCTGACCATCAGGGTGTCCTGGGGAGATGGCACAGAAACTAAAGTCCTGCAGAGTGGAGC
ATCTCTGCAGATCCAAGAGGGTGAGTCCCTGCGCCTGGTCTGTGTGGCAGACAGCAACCCCTCT
GCCATGCTGAGCTGGAAGCGCCAGACCCAGAAGAACTTCCGGCTCTCTAAGGGTGATGAACTTC
AACTGCCACGGGTGGAGTTGGAGGACCAGGGAAAATACATCTGCCAGGCTAAGAACAGTCTGGG
TACTCAGACAGCCTCTGTGAGCCTCAGCATAAGGAGCCTTCTACAGCTGCTGGCACCCTCCTGC
TCCTGGGATTCTGAGGGTCTGCACTGCAGCTGCTCCTCCAGAGCCTGGCCTGCCCCGTCCCTGG
GCTGGCGGCTGGGGGAGGGGCTGCTGGAGGGAAACAGCAGCAATGCCTCCTTCACAGTTATGTC
CAGCTCTGCAGGACCGTGGGTCAACAGCTCCCTGAGCCTCAGTGTGGAATTCAGCACTGACCAC
AGACTCAGCTGTGAAGCTTGGAATGACTATGGAGTTCAGAGAGCCACTATCGTGCTGGTTCCAG
GACAAGGAGTCTCACAGGACAAATCAGAAACCAGTGGAGGAGCGGTTCAGGGGGCCATCTGGGG
AGCTGGTCTTATGGCTTTGCTTGCTGTCTCCTTCTGCCTCATCTTCTTCATAGTGAAGTTCCTC
AGGAAGAAATCAGCATTGGAAGTAGCAGCCATGGAAGGCAACCACCTTGCCAAGAACCTTGTCT
CCACCATAAATAGTGCAAGCATGATTTCGTCCAACATTCCATTGAGATACCCCATCCAGGATCA
TCTGAATGAATCAGAGTCACAGACCCAGAAAGAAGAGCCACCTCTTGCCACAGCCCCAGACATC
CCAAAGGATGAGCCCGAACTTCACTATGCCTCCCTCTCCTTCCAAGGTCCGAGGCCCCAGCAGC
CAAAGAACACGGAGACCATCAAGTCTGTTTACACAGAGATCAAGATTCACAAGCGCTGAAGCTC
CTTGCCCCATGTGTCAGTCACAGTGCTGGCTGGAGTCCCAGAAAGGCATGGCTGAAGATAGCAT
GTGTTAGGAGCATATTCTGGCATCAGTGGCCCTCTTAACCAAAGGATATGTAGTGGAAGGAGGG
AGTTTTGGAAGGAGAGAAGGTTACAGAGATTCCTAGGTTCAAATCCATATTCAGTGTTATTCCC
AGAGAAGCCACCTTTTTTCTTTGTGCCCCCTCTTCCTCCTCTGTAAAGTGGAGTCATAATCTGA
GGAGTACCAAGGAGAGAATGTGTTTATTGTTGATTATATTGCTTTATGTTGCCTGAGCAGTGGG
GAAGAACGTTTTGTCTTTATTGCATAACTTGAATTTTACTTGTATATTTTTAAAGAACATATGT
TAGTTCCTAAAGTTATTCTGTTTTGAAGTGTGACTGTGTTGTAGCTACCTGTATCTCAGATTGG
ACTCATTGGACATTCTGCAAACTCTTAAAGATCATACAGATATCAGCCCAGACTACTATACCCA
GTAAAATTAACAATCATGGGGCATAAAGCTAATATATAAAGATCTCCCACAAATCAATAAAAGT
GACAGACAATTCAATACAAAATGGTAATATGTGAGTGGTAAGCAAACATACAGAAAGGTGACCA
ATCAGTGCTTGTCAACGAAATATAAATAAATACAGTACACCT

hide sequence

RefSeq Acc Id:

XM_006228946 ⟹ XP_006229008

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	102,904,705 - 102,913,196 (+)	NCBI
mRatBN7.2	1	93,768,190 - 93,776,696 (+)	NCBI
Rnor_6.0	1	98,562,436 - 98,570,872 (-)	NCBI
Rnor_5.0	1	99,630,691 - 99,647,749 (-)	NCBI

Sequence:

show sequence

ATGATGCCACACAGGAAAAGTGGAAGTGTTTATTTTCCAAGGGCCTTGATATCGCTGATAACCT
GCGGGTGGAAAGTTCCTTCCTTCTCTGTGGTCAGTCACCCTGCCTCTCTTCATTCCTGGGCTAG
GTCAGTAGGACGACTTCTCAGTCCTGTGACATTGAAGCCTATGACCCTCGAACTGACCAAGTTT
TCTGTCTCTGGAGCCTAGGACCTTTCACTGCGTGATGCTGTGGGCACAGCTGCTGCCCCTGCTG
TGGGCAGGGTCCCTGGCCGTGGAGAATTATGAGCTCTCATTGACTGAATCAGTGACGGTGCAGG
AGGGTCTGTGCGTCTTTGTACCCTGCCAAGTCAAGTACCCTGCTTCCGGGGGTTCTGTTTTTGG
CTACTGGTTCCAGGATGGGGCCAACACAAACCTCAACTCTCCAGTGGCTACAAATGACCCACAT
CGACCAGTACAGCAGGAAACTCAAGGTCGTTTCTATCTCGTGGGGGGCATAGATACTAAAAATT
GCTCCCTGGACATCAGAGACGCACGGAAAAGTGACACAGGAAAGTACTTCTTCAGGTTGGATGG
AAGTGTGAAATACAGTTTCCGGAATCGGATGCTCTCTGTGCATGTGACAGCTCTGACTAAGACC
CCTAACCTCCAAGTCACATCTACCCTGGTGTCTGGCACTTCTACCCGAGTGATCTGTTCTGTGC
TCTGGGCCTGTGAGCAGGGGACACCCCCCATCTTTTCCTGGATGTCATCTGCCCTCACTTCCCT
GGGCCGCAGAACCATCCTCTCCTCAGAGCTGAACCTCACACCTAGGCCTCAGGACAACGGCACC
AACCTCATCTGTCAGGTGACCTTCCCTGGTGCTGGTGTTACTGTGGAGAGGACTCAACAGCTCA
GTGTCACCTATGCTCCACAGAAGCTGACCATCAGGGTGTCCTGGGGAGATGGCACAGAAACTAA
AGTCCTGCAGAGTGGAGCATCTCTGCAGATCCAAGAGGGTGAGTCCCTGCGCCTGGTCTGTGTG
GCAGACAGCAACCCCTCTGCCATGCTGAGCTGGAAGCGCCAGACCCAGAAGAACTTCCGGCTCT
CTAAGGGTGATGAACTTCAACTGCCACGGGTGGAGTTGGAGGACCAGGGAAAATACATCTGCCA
GGCTAAGAACAGTCTGGGTACTCAGACAGCCTCTGTGAGCCTCAGCATAAGGAGCCTTCTACAG
CTGCTGGCACCCTCCTGCTCCTGGGATTCTGAGGGTCTGCACTGCAGCTGCTCCTCCAGAGCCT
GGCCTGCCCCGTCCCTGGGCTGGCGGCTGGGGGAGGGGCTGCTGGAGGGAAACAGCAGCAATGC
CTCCTTCACAGTTATGTCCAGCTCTGCAGGACCGTGGGTCAACAGCTCCCTGAGCCTCAGTGTG
GAATTCAGCACTGACCACAGACTCAGCTGTGAAGCTTGGAATGACTATGGAGTTCAGAGAGCCA
CTATCGTGCTGGTTCCAGGACAAGGAGTCTCACAGGCAGACAAATCAGAAACCAGTGGAGGAGC
GGTTCAGGGGGCCATCTGGGGAGCTGGTCTTATGGCTTTGCTTGCTGTCTCCTTCTGCCTCATC
TTCTTCATAGTGAAGTTCCTCAGGAAGAAATCAGCATTGGAAGTAGCAGCCATGGAAGGCAACC
ACCTTGCCAAGAACCTTGTCTCCACCATAAATAGTGCAAGCATGATTTCGTCCAACATTCCATT
GAGATACCCCATCCAGGATCATCTGAATGAATCAGAGTCACAGACCCAGAAAGAAGAGCCACCT
CTTGCCACAGCCCCAGACATCCCAAAGGATGAGCCCGAACTTCACTATGCCTCCCTCTCCTTCC
AAGGTCCGAGGCCCCAGCAGCCAAAGAACACGGAGACCATCAAGTCTGTTTACACAGAGATCAA
GATTCACAAGCGCTGAAGCTCCTTGCCCCATGTGTCAGTCACAGTGCTGGCTGGAGTCCCAGAA
AGGCATGGCTGAAGATAGCATGTGTTAGGAGCATATTCTGGCATCAGTGGCCCTCTTAACCAAA
GGATATGTAGTGGAAGGAGGGAGTTTTGGAAGGAGAGAAGGTTACAGAGATTCCTAGGTTCAAA
TCCATATTCAGTGTTATTCCCAGAGAAGCCACCTTTTTTCTTTGTGCCCCCTCTTCCTCCTCTG
TAAAGTGGAGTCATAATCTGAGGAGTACCAAGGAGAGAATGTGTTTATTGTTGATTATATTGCT
TTATGTTGCCTGAGCAGTGGGGAAGAACGTTTTGTCTTTATTGCATAACTTGAATTTTACTTGT
ATATTTTTAAAGAACATATGTTAGTTCCTAAAGTTATTCTGTTTTGAAGTGTGACTGTGTTGTA
GCTACCTGTATCTCAGATTGGACTCATTGGACATTCTGCAAACTCTTAAAGATCATACAGATAT
CAGCCCAGACTACTATACCCAGTAAAATTAACAATCATGGGGCATAAAGCTAATATATAAAGAT
CTCCCACAAATCAATAAAAGTGACAGACAATTCAATACAAAA

hide sequence

RefSeq Acc Id:

XM_039104606 ⟹ XP_038960534

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	102,904,771 - 102,910,305 (+)	NCBI
mRatBN7.2	1	93,768,190 - 93,773,711 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099719	(Get FASTA)	NCBI Sequence Viewer
	NP_001424367	(Get FASTA)	NCBI Sequence Viewer
	XP_006229008	(Get FASTA)	NCBI Sequence Viewer
	XP_038960534	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM07562	(Get FASTA)	NCBI Sequence Viewer
	EDM07563	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000034882
	ENSRNOP00000034882.4
	ENSRNOP00000088341
	ENSRNOP00000088341.1
	ENSRNOP00000111595.1

RefSeq Acc Id:	NP_001099719 ⟸ NM_001106249
- Peptide Label:	precursor
- UniProtKB:	A6JAH1 (UniProtKB/TrEMBL), A0A8I6AAM7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLWAQLLPLLWAGSLAVENYELSLTESVTVQEGLCVFVPCQVKYPASGGSVFGYWFQDGANTNL NSPVATNDPHRPVQQETQGRFYLVGGIDTKNCSLDIRDARKSDTGKYFFRLDGSVKYSFRNRML SVHVTALTKTPNLQVTSTLVSGTSTRVICSVLWACEQGTPPIFSWMSSALTSLGRRTILSSELN LTPRPQDNGTNLICQVTFPGAGVTVERTQQLSVTYAPQKLTIRVSWGDGTETKVLQSGASLQIQ EGESLRLVCVADSNPSAMLSWKRQTQKNFRLSKGDELQLPRVELEDQGKYICQAKNSLGTQTAS VSLSIRSLLQLLAPSCSWDSEGLHCSCSSRAWPAPSLGWRLGEGLLEGNSSNASFTVMSSSAGP WVNSSLSLSVEFSTDHRLSCEAWNDYGVQRATIVLVPGQGVSQDKSETSGGAVQGAIWGAGLMA LLAVSFCLIFFIVKFLRKKSALEVAAMEGNHLAKNLVSTINSASMISSNIPLRYPIQDHLNESE SQTQKEEPPLATAPDIPKDEPELHYASLSFQGPRPQQPKNTETIKSVYTEIKIHKR hide sequence

RefSeq Acc Id:

XP_006229008 ⟸ XM_006228946

- Peptide Label:

isoform X1

- Sequence:

show sequence

MLWAQLLPLLWAGSLAVENYELSLTESVTVQEGLCVFVPCQVKYPASGGSVFGYWFQDGANTNL
NSPVATNDPHRPVQQETQGRFYLVGGIDTKNCSLDIRDARKSDTGKYFFRLDGSVKYSFRNRML
SVHVTALTKTPNLQVTSTLVSGTSTRVICSVLWACEQGTPPIFSWMSSALTSLGRRTILSSELN
LTPRPQDNGTNLICQVTFPGAGVTVERTQQLSVTYAPQKLTIRVSWGDGTETKVLQSGASLQIQ
EGESLRLVCVADSNPSAMLSWKRQTQKNFRLSKGDELQLPRVELEDQGKYICQAKNSLGTQTAS
VSLSIRSLLQLLAPSCSWDSEGLHCSCSSRAWPAPSLGWRLGEGLLEGNSSNASFTVMSSSAGP
WVNSSLSLSVEFSTDHRLSCEAWNDYGVQRATIVLVPGQGVSQADKSETSGGAVQGAIWGAGLM
ALLAVSFCLIFFIVKFLRKKSALEVAAMEGNHLAKNLVSTINSASMISSNIPLRYPIQDHLNES
ESQTQKEEPPLATAPDIPKDEPELHYASLSFQGPRPQQPKNTETIKSVYTEIKIHKR

hide sequence

Ensembl Acc Id:

ENSRNOP00000034882 ⟸ ENSRNOT00000033648

RefSeq Acc Id:	XP_038960534 ⟸ XM_039104606
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000088341 ⟸ ENSRNOT00000106528

Ensembl Acc Id:

ENSRNOP00000111595 ⟸ ENSRNOT00000171344

Protein Domains

Ig-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3Z9T4-F1-model_v2	AlphaFold	D3Z9T4	1-569	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305432	AgrOrtholog
BioCyc Gene	G2FUF-59859	BioCyc
Ensembl Genes	ENSRNOG00000021474	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000033648	ENTREZGENE
	ENSRNOT00000033648.6	UniProtKB/TrEMBL
	ENSRNOT00000106528	ENTREZGENE
	ENSRNOT00000106528.2	UniProtKB/TrEMBL
	ENSRNOT00000171344.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	Ig-like	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_I-set	UniProtKB/TrEMBL
	Ig_sub	UniProtKB/TrEMBL
	Ig_sub2	UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/TrEMBL
	SIGLEC	UniProtKB/TrEMBL
KEGG Report	rno:292843	UniProtKB/TrEMBL
NCBI Gene	292843	ENTREZGENE
PANTHER	SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN	UniProtKB/TrEMBL
	SIALIC ACID-BINDING IG-LIKE LECTIN 5	UniProtKB/TrEMBL
Pfam	I-set	UniProtKB/TrEMBL
	V-set	UniProtKB/TrEMBL
PhenoGen	Siglec5	PhenoGen
PROSITE	IG_LIKE	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000021474	RatGTEx
SMART	IGc2	UniProtKB/TrEMBL
	SM00409	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
UniProt	A0A8I6AAM7	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0M7S7_RAT	UniProtKB/TrEMBL
	A6JAH1	ENTREZGENE, UniProtKB/TrEMBL
	D3Z9T4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Siglec5	sialic acid binding Ig-like lectin 5	Siglec5_predicted	sialic acid binding Ig-like lectin 5 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Siglec5_predicted	sialic acid binding Ig-like lectin 5 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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