Pdzrn3 (PDZ domain containing RING finger 3) - Rat Genome Database

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Gene: Pdzrn3 (PDZ domain containing RING finger 3) Rattus norvegicus
Analyze
Symbol: Pdzrn3
Name: PDZ domain containing RING finger 3
RGD ID: 1305250
Description: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in neuromuscular junction development and protein ubiquitination. Predicted to be located in cytoplasm and synapse. Predicted to be active in neuromuscular junction. Orthologous to human PDZRN3 (PDZ domain containing ring finger 3); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase PDZRN3; LOC312607; PDZ domain-containing RING finger protein 3; RING-type E3 ubiquitin transferase PDZRN3; semaphorin cytoplasmic domain-associated protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84135,327,082 - 135,553,294 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4135,327,082 - 135,553,294 (-)EnsemblGRCr8
mRatBN7.24133,770,736 - 133,996,959 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4133,770,736 - 133,996,959 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4139,182,993 - 139,416,031 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04134,963,779 - 135,196,808 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04133,584,382 - 133,817,407 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04133,717,139 - 133,951,282 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4133,717,139 - 133,951,264 (-)Ensemblrn6Rnor6.0
Rnor_5.04198,194,465 - 198,429,457 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44136,044,210 - 136,254,969 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4122,607,053 - 122,831,741 (-)NCBICelera
RGSC_v3.14136,260,810 - 136,311,636 (-)NCBI
Cytogenetic Map4q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
andrographolide  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
dexamethasone  (ISO)
dibenzofurans  (ISO)
dibutyl phthalate  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dorsomorphin  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
glafenine  (EXP)
haloperidol  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
inulin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenformin  (EXP)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
profenofos  (EXP)
SB 431542  (ISO)
Securinine  (ISO)
senecionine  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (ISO)
neuromuscular junction  (IBA,ISO)
synapse  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15057822   PMID:15458844   PMID:17576800   PMID:22609016   PMID:28623232  


Genomics

Comparative Map Data
Pdzrn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84135,327,082 - 135,553,294 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4135,327,082 - 135,553,294 (-)EnsemblGRCr8
mRatBN7.24133,770,736 - 133,996,959 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4133,770,736 - 133,996,959 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4139,182,993 - 139,416,031 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04134,963,779 - 135,196,808 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04133,584,382 - 133,817,407 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04133,717,139 - 133,951,282 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4133,717,139 - 133,951,264 (-)Ensemblrn6Rnor6.0
Rnor_5.04198,194,465 - 198,429,457 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44136,044,210 - 136,254,969 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4122,607,053 - 122,831,741 (-)NCBICelera
RGSC_v3.14136,260,810 - 136,311,636 (-)NCBI
Cytogenetic Map4q34NCBI
PDZRN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38373,382,431 - 73,624,941 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl373,382,431 - 73,624,941 (-)Ensemblhg38GRCh38
GRCh37373,431,582 - 73,674,092 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36373,514,342 - 73,756,762 (-)NCBIBuild 36Build 36hg18NCBI36
Celera373,365,735 - 73,608,750 (-)NCBICelera
Cytogenetic Map3p13NCBI
HuRef373,434,331 - 73,676,506 (-)NCBIHuRef
CHM1_1373,385,013 - 73,627,407 (-)NCBICHM1_1
T2T-CHM13v2.0373,423,926 - 73,666,429 (-)NCBIT2T-CHM13v2.0
Pdzrn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396101,126,568 - 101,354,858 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6101,126,570 - 101,354,858 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386101,149,607 - 101,377,897 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6101,149,609 - 101,377,897 (-)Ensemblmm10GRCm38
MGSCv376101,099,601 - 101,327,891 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366101,115,712 - 101,343,995 (-)NCBIMGSCv36mm8
Celera6103,016,258 - 103,244,142 (-)NCBICelera
Cytogenetic Map6D3NCBI
cM Map646.95NCBI
Pdzrn3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542114,648,524 - 14,877,822 (+)Ensembl
ChiLan1.0NW_00495542114,648,436 - 14,878,759 (+)NCBIChiLan1.0ChiLan1.0
PDZRN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2273,337,666 - 73,581,399 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1373,342,455 - 73,586,188 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0373,322,613 - 73,565,929 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1375,245,623 - 75,488,415 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl375,246,558 - 75,488,499 (-)EnsemblpanPan2panpan1.1
PDZRN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12018,621,960 - 18,859,620 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2018,622,069 - 18,859,550 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2018,594,042 - 18,830,979 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02018,656,854 - 18,893,815 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2018,656,915 - 18,893,825 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12018,344,911 - 18,581,831 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02018,685,052 - 18,922,922 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02018,750,258 - 18,987,822 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pdzrn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049424,218,675 - 4,420,201 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366034,218,212 - 4,420,087 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366034,218,675 - 4,423,450 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDZRN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1354,659,589 - 54,904,809 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11354,659,657 - 54,904,742 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21360,422,724 - 60,650,319 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PDZRN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12234,325,208 - 34,567,748 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2234,326,144 - 34,567,633 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041132,201,578 - 132,443,428 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pdzrn3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247737,900,934 - 8,144,003 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247737,901,560 - 8,144,455 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Pdzrn3
2250 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:45
Interacting mature miRNAs:50
Transcripts:ENSRNOT00000039201
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486583980149763391Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)496731383141731383Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4107346299152346299Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)492406430137406430Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4117737142152833657Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4111383604156383604Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4108206096153206096Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4111383604156383604Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4134199006168870974Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4113634167149763391Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4103834277148834277Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4121020385148834277Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat

Markers in Region
D4Rat58  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr84135,378,340 - 135,378,687 (+)Marker Load Pipeline
mRatBN7.24133,821,995 - 133,822,342 (+)MAPPERmRatBN7.2
Rnor_6.04133,776,133 - 133,776,479NCBIRnor6.0
Rnor_5.04198,254,543 - 198,254,889UniSTSRnor5.0
RGSC_v3.44136,095,832 - 136,096,179RGDRGSC3.4
RGSC_v3.44136,095,833 - 136,096,179UniSTSRGSC3.4
Celera4122,658,291 - 122,658,637UniSTS
RGSC_v3.14136,340,671 - 136,341,022RGD
SHRSP x BN Map460.61UniSTS
SHRSP x BN Map460.61RGD
Cytogenetic Map4q34UniSTS
RH128427  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.04198,194,524 - 198,194,708NCBIRnor5.0
RGSC_v3.44136,044,276 - 136,044,459UniSTSRGSC3.4
Celera4122,607,113 - 122,607,296UniSTS
RH 3.4 Map4809.0UniSTS
Cytogenetic Map4q34UniSTS
RH129369  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24133,884,426 - 133,884,636 (+)MAPPERmRatBN7.2
Rnor_6.04133,838,559 - 133,838,768NCBIRnor6.0
Rnor_5.04198,316,969 - 198,317,178UniSTSRnor5.0
RGSC_v3.44136,158,259 - 136,158,468UniSTSRGSC3.4
Celera4122,720,663 - 122,720,872UniSTS
RH 3.4 Map4808.9UniSTS
Cytogenetic Map4q34UniSTS
BF395872  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24133,893,687 - 133,893,880 (+)MAPPERmRatBN7.2
Rnor_6.04133,847,819 - 133,848,011NCBIRnor6.0
Rnor_5.04198,326,229 - 198,326,421UniSTSRnor5.0
RGSC_v3.44136,167,519 - 136,167,711UniSTSRGSC3.4
Celera4122,729,914 - 122,730,106UniSTS
RH 3.4 Map4810.32UniSTS
Cytogenetic Map4q34UniSTS
RH141666  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24133,837,561 - 133,837,742 (+)MAPPERmRatBN7.2
Rnor_6.04133,791,699 - 133,791,879NCBIRnor6.0
Rnor_5.04198,270,109 - 198,270,289UniSTSRnor5.0
RGSC_v3.44136,111,399 - 136,111,579UniSTSRGSC3.4
Celera4122,673,857 - 122,674,037UniSTS
RH 3.4 Map4808.0UniSTS
Cytogenetic Map4q34UniSTS
AI008935  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24133,919,855 - 133,920,036 (+)MAPPERmRatBN7.2
Rnor_6.04133,873,953 - 133,874,133NCBIRnor6.0
Rnor_5.04198,352,042 - 198,352,222UniSTSRnor5.0
RGSC_v3.44136,178,084 - 136,178,264UniSTSRGSC3.4
Celera4122,755,027 - 122,755,207UniSTS
RH 3.4 Map4810.32UniSTS
Cytogenetic Map4q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 158 91 90 59 39 59 6 303 139 11 137 81 92 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000090506   ⟹   ENSRNOP00000073080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4135,327,082 - 135,553,294 (-)Ensembl
mRatBN7.2 Ensembl4133,770,736 - 133,996,959 (-)Ensembl
Rnor_6.0 Ensembl4133,717,139 - 133,951,264 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000124600   ⟹   ENSRNOP00000099377
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4135,327,082 - 135,553,294 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000152267   ⟹   ENSRNOP00000111488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4135,327,082 - 135,553,294 (-)Ensembl
RefSeq Acc Id: NM_001271251   ⟹   NP_001258180
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84135,327,082 - 135,553,294 (-)NCBI
mRatBN7.24133,770,736 - 133,996,959 (-)NCBI
Rnor_6.04133,717,139 - 133,951,264 (-)NCBI
Rnor_5.04198,194,465 - 198,429,457 (-)NCBI
Celera4122,607,053 - 122,831,741 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592642   ⟹   XP_017448131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84135,327,082 - 135,375,082 (-)NCBI
mRatBN7.24133,770,736 - 133,818,888 (-)NCBI
Rnor_6.04133,717,470 - 133,775,301 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001258180 (Get FASTA)   NCBI Sequence Viewer  
  XP_017448131 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL91453 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073080
GenBank Protein P68907 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001258180   ⟸   NM_001271251
- UniProtKB: P68907 (UniProtKB/Swiss-Prot),   A0A0G2K4K7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448131   ⟸   XM_017592642
- Peptide Label: isoform X1
- UniProtKB: A6IBI4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073080   ⟸   ENSRNOT00000090506
Ensembl Acc Id: ENSRNOP00000111488   ⟸   ENSRNOT00000152267
Ensembl Acc Id: ENSRNOP00000099377   ⟸   ENSRNOT00000124600
Protein Domains
PDZ   RING-type   TRAF-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P68907-F1-model_v2 AlphaFold P68907 1-1062 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305250 AgrOrtholog
BioCyc Gene G2FUF-43521 BioCyc
Ensembl Genes ENSRNOG00000057556 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000090506 ENTREZGENE
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
InterPro E3_ubiquitin-PDZ_ligase UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  PDZ_sf UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
  Znf_RING_CS UniProtKB/Swiss-Prot
  Znf_TRAF UniProtKB/Swiss-Prot
NCBI Gene 312607 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE PDZRN3 UniProtKB/Swiss-Prot
  PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4 UniProtKB/Swiss-Prot
Pfam PDZ UniProtKB/Swiss-Prot
  zf-C3HC4_2 UniProtKB/Swiss-Prot
PhenoGen Pdzrn3 PhenoGen
PROSITE PDZ UniProtKB/Swiss-Prot
  ZF_RING_1 UniProtKB/Swiss-Prot
  ZF_RING_2 UniProtKB/Swiss-Prot
  ZF_TRAF UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000057556 RatGTEx
SMART PDZ UniProtKB/Swiss-Prot
  RING UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
  SSF50156 UniProtKB/Swiss-Prot
  TRAF domain-like UniProtKB/Swiss-Prot
UniProt A0A0G2K4K7 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L671_RAT UniProtKB/TrEMBL
  A0ABK0M7K4_RAT UniProtKB/TrEMBL
  A6IBI4 ENTREZGENE, UniProtKB/TrEMBL
  P68907 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Pdzrn3  PDZ domain containing RING finger 3   Pdzrn3_predicted  PDZ domain containing RING finger 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pdzrn3_predicted  PDZ domain containing RING finger 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED