Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nt5dc1 | Rat | (S)-nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of NT5DC1 mRNA | CTD | PMID:27782041 | Nt5dc1 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Nt5dc1 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of NT5DC1 mRNA | CTD | PMID:22206623 | Nt5dc1 | Rat | 1-chloro-2,4-dinitrobenzene | affects binding | ISO | NT5DC1 (Homo sapiens) | 6480464 | Dinitrochlorobenzene binds to NT5DC1 protein | CTD | PMID:32991956 | Nt5dc1 | Rat | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | increases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Metribolone results in increased expression of NT5C2L1 protein | CTD | PMID:17152098 | Nt5dc1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Nt5dc1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NT5DC1 mRNA | CTD | PMID:21570461 | Nt5dc1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NT5DC1 mRNA | CTD | PMID:33387578 | Nt5dc1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Nt5dc1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NT5DC1 mRNA | CTD | PMID:33956508 | Nt5dc1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Nt5dc1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of NT5DC1 mRNA | CTD | PMID:39298647 | Nt5dc1 | Rat | actinomycin D | multiple interactions | ISO | NT5DC1 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of NT5DC1 protein | CTD | PMID:38460933 | Nt5dc1 | Rat | aflatoxin B1 | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of NT5DC1 mRNA | CTD | PMID:27153756 | Nt5dc1 | Rat | all-trans-retinoic acid | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of NT5DC1 mRNA | CTD | PMID:33167477 | Nt5dc1 | Rat | aristolochic acid A | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of NT5DC1 mRNA | CTD | PMID:33212167 | Nt5dc1 | Rat | aristolochic acid A | increases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of NT5DC1 protein | CTD | PMID:33212167 | Nt5dc1 | Rat | arsenite(3-) | increases expression | ISO | Nt5dc1 (Mus musculus) | 6480464 | arsenite results in increased expression of NT5DC1 protein | CTD | PMID:37955338 | Nt5dc1 | Rat | benzo[a]pyrene | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of NT5DC1 mRNA | CTD | PMID:26238291|PMID:32234424 | Nt5dc1 | Rat | benzo[a]pyrene | decreases methylation | ISO | Nt5dc1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of NT5DC1 intron | CTD | PMID:27901495 | Nt5dc1 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NT5DC1 mRNA | CTD | PMID:20018196|PMID:26238291 | Nt5dc1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NT5DC1 mRNA | CTD | PMID:25181051 | Nt5dc1 | Rat | bisphenol A | increases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of NT5DC1 protein | CTD | PMID:34186270 | Nt5dc1 | Rat | bisphenol A | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of NT5DC1 protein | CTD | PMID:37567409 | Nt5dc1 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of NT5DC1 gene | CTD | PMID:28505145 | Nt5dc1 | Rat | Bisphenol B | increases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of NT5DC1 protein | CTD | PMID:34186270 | Nt5dc1 | Rat | bisphenol F | increases expression | ISO | Nt5dc1 (Mus musculus) | 6480464 | bisphenol F results in increased expression of NT5DC1 mRNA | CTD | PMID:38685157 | Nt5dc1 | Rat | bisphenol F | increases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of NT5DC1 protein | CTD | PMID:34186270 | Nt5dc1 | Rat | Butylbenzyl phthalate | increases expression | ISO | Nt5dc1 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased expression of NT5DC1 mRNA | CTD | PMID:28392331 | Nt5dc1 | Rat | cadmium dichloride | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of NT5DC1 mRNA | CTD | PMID:38568856 | Nt5dc1 | Rat | chlorpyrifos | decreases expression | ISO | Nt5dc1 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of NT5DC1 mRNA | CTD | PMID:37019170 | Nt5dc1 | Rat | cisplatin | multiple interactions | ISO | NT5DC1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of NT5DC1 mRNA | CTD | PMID:27392435 | Nt5dc1 | Rat | cisplatin | increases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of NT5DC1 mRNA | CTD | PMID:27392435 | Nt5dc1 | Rat | clorgyline | increases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Clorgyline results in increased expression of NT5DC1 mRNA | CTD | PMID:19691856 | Nt5dc1 | Rat | copper(II) sulfate | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of NT5DC1 mRNA | CTD | PMID:19549813 | Nt5dc1 | Rat | cyclosporin A | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of NT5DC1 mRNA | CTD | PMID:20106945|PMID:25562108 | Nt5dc1 | Rat | dicrotophos | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of NT5DC1 mRNA | CTD | PMID:28302478 | Nt5dc1 | Rat | dimethyl sulfoxide | increases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Dimethyl Sulfoxide results in increased expression of NT5DC1 mRNA | CTD | PMID:39709020 | Nt5dc1 | Rat | disodium selenite | increases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of NT5C2L1 mRNA | CTD | PMID:18175754 | Nt5dc1 | Rat | dorsomorphin | multiple interactions | ISO | NT5DC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Nt5dc1 | Rat | doxorubicin | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of NT5DC1 mRNA | CTD | PMID:29803840 | Nt5dc1 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of NT5DC1 mRNA | CTD | PMID:29391264 | Nt5dc1 | Rat | enzyme inhibitor | multiple interactions | ISO | NT5DC1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... | CTD | PMID:23301498 | Nt5dc1 | Rat | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of NT5DC1 mRNA | CTD | PMID:23962444 | Nt5dc1 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of NT5DC1 mRNA | CTD | PMID:24793618 | Nt5dc1 | Rat | genistein | increases methylation | EXP | | 6480464 | Genistein results in increased methylation of NT5DC1 gene | CTD | PMID:28505145 | Nt5dc1 | Rat | inulin | multiple interactions | ISO | Nt5dc1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of NT5DC1 mRNA | CTD | PMID:36331819 | Nt5dc1 | Rat | ivermectin | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of NT5DC1 protein | CTD | PMID:32959892 | Nt5dc1 | Rat | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of NT5DC1 mRNA | CTD | PMID:24136188 | Nt5dc1 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of NT5DC1 mRNA | CTD | PMID:30467583 | Nt5dc1 | Rat | methylmercury chloride | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of NT5DC1 mRNA | CTD | PMID:28001369 | Nt5dc1 | Rat | nicotine | increases expression | EXP | | 6480464 | Nicotine results in increased expression of NT5DC1 mRNA | CTD | PMID:27782041 | Nt5dc1 | Rat | Nutlin-3 | multiple interactions | ISO | NT5DC1 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of NT5DC1 protein | CTD | PMID:38460933 | Nt5dc1 | Rat | okadaic acid | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of NT5DC1 mRNA | CTD | PMID:38832940 | Nt5dc1 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of NT5DC1 mRNA | CTD | PMID:25729387 | Nt5dc1 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of NT5DC1 mRNA | CTD | PMID:33387578 | Nt5dc1 | Rat | pentachlorophenol | increases expression | ISO | Nt5dc1 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of NT5DC1 mRNA | CTD | PMID:23892564 | Nt5dc1 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Nt5dc1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of NT5DC1 mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Nt5dc1 | Rat | phenytoin | increases expression | EXP | | 6480464 | Phenytoin results in increased expression of NT5DC1 mRNA | CTD | PMID:20345932 | Nt5dc1 | Rat | pirinixic acid | increases expression | ISO | Nt5dc1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of NT5DC1 mRNA | CTD | PMID:18301758|PMID:23811191 | Nt5dc1 | Rat | SB 431542 | multiple interactions | ISO | NT5DC1 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of NT5DC1 more ... | CTD | PMID:27188386|PMID:37664457 | Nt5dc1 | Rat | sodium arsenite | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of NT5DC1 mRNA | CTD | PMID:38568856 | Nt5dc1 | Rat | sodium arsenite | increases expression | ISO | Nt5dc1 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of NT5DC1 mRNA | CTD | PMID:36209798 | Nt5dc1 | Rat | sunitinib | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of NT5DC1 mRNA | CTD | PMID:31533062 | Nt5dc1 | Rat | titanium dioxide | decreases expression | ISO | Nt5dc1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of NT5DC1 mRNA | CTD | PMID:29264374 | Nt5dc1 | Rat | titanium dioxide | decreases methylation | ISO | Nt5dc1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of NT5DC1 gene | CTD | PMID:35295148 | Nt5dc1 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of NT5DC1 mRNA | CTD | PMID:25729387 | Nt5dc1 | Rat | trichostatin A | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of NT5DC1 mRNA | CTD | PMID:24935251|PMID:26272509 | Nt5dc1 | Rat | trichostatin A | multiple interactions | ISO | NT5DC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Nt5dc1 | Rat | triptonide | decreases expression | ISO | Nt5dc1 (Mus musculus) | 6480464 | triptonide results in decreased expression of NT5DC1 mRNA | CTD | PMID:33045310 | Nt5dc1 | Rat | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of NT5DC1 mRNA | CTD | PMID:24136188 | Nt5dc1 | Rat | valproic acid | decreases methylation | ISO | NT5DC1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of NT5DC1 gene | CTD | PMID:29154799 | Nt5dc1 | Rat | valproic acid | affects expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NT5DC1 mRNA | CTD | PMID:25979313 | Nt5dc1 | Rat | valproic acid | decreases expression | ISO | NT5DC1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of NT5DC1 mRNA | CTD | PMID:23179753|PMID:24935251|PMID:28001369 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















