Rnf43 (ring finger protein 43) - Rat Genome Database

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Gene: Rnf43 (ring finger protein 43) Rattus norvegicus
Analyze
Symbol: Rnf43
Name: ring finger protein 43
RGD ID: 1305204
Description: Predicted to enable frizzled binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including Wnt receptor catabolic process; stem cell proliferation; and ubiquitin-dependent protein catabolic process. Predicted to be located in endoplasmic reticulum membrane and nuclear envelope. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in endometrial cancer; gastrointestinal system cancer (multiple); irritable bowel syndrome; lung adenocarcinoma; and villous adenoma. Orthologous to human RNF43 (ring finger protein 43); PARTICIPATES IN Wnt signaling, canonical pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase RNF43; LOC303412; RGD1305204; similar to hypothetical protein FLJ20315
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Bp308
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81072,958,744 - 73,034,540 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1072,961,641 - 73,034,551 (+)EnsemblGRCr8
mRatBN7.21072,461,508 - 72,537,301 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1072,464,348 - 72,536,977 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1077,076,871 - 77,146,437 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01076,581,783 - 76,651,384 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01072,046,299 - 72,115,890 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01074,956,411 - 75,028,951 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1074,959,285 - 75,028,951 (+)Ensemblrn6Rnor6.0
Rnor_5.01075,073,437 - 75,145,501 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41075,957,792 - 76,027,392 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1071,380,030 - 71,449,285 (+)NCBICelera
RGSC_v3.11075,970,268 - 76,041,762 (+)NCBI
Cytogenetic Map10q26NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
chrysene  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethylparaben  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
leflunomide  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
okadaic acid  (ISO)
oxaliplatin  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis. Bond CE, etal., Oncotarget. 2016 Oct 25;7(43):70589-70600. doi: 10.18632/oncotarget.12130.
2. Impact of loss-of-function mutations at the RNF43 locus on colorectal cancer development and progression. Eto T, etal., J Pathol. 2018 Aug;245(4):445-455. doi: 10.1002/path.5098. Epub 2018 Jun 20.
3. Genomic landscape of colitis-associated cancer indicates the impact of chronic inflammation and its stratification by mutations in the Wnt signaling. Fujita M, etal., Oncotarget. 2017 Dec 12;9(1):969-981. doi: 10.18632/oncotarget.22867. eCollection 2018 Jan 2.
4. Germline mutations in oncogene-induced senescence pathways are associated with multiple sessile serrated adenomas. Gala MK, etal., Gastroenterology. 2014 Feb;146(2):520-9.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. RNF43 is frequently mutated in colorectal and endometrial cancers. Giannakis M, etal., Nat Genet. 2014 Dec;46(12):1264-6. doi: 10.1038/ng.3127. Epub 2014 Oct 26.
7. DDB2 Is a Novel Regulator of Wnt Signaling in Colon Cancer. Huang S, etal., Cancer Res. 2017 Dec 1;77(23):6562-6575. doi: 10.1158/0008-5472.CAN-17-1570. Epub 2017 Oct 11.
8. Frequent frameshift mutations in 2 mononucleotide repeats of RNF43 gene and its regional heterogeneity in gastric and colorectal cancers. Jo YS, etal., Hum Pathol. 2015 Nov;46(11):1640-6. doi: 10.1016/j.humpath.2015.07.004. Epub 2015 Jul 15.
9. Cytotoxic T lymphocyte response to peptide vaccination predicts survival in stage III colorectal cancer. Kawamura J, etal., Cancer Sci. 2018 May;109(5):1545-1551. doi: 10.1111/cas.13547. Epub 2018 Mar 31.
10. The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated beta-catenin by sequestering TCF4 to the nuclear membrane. Loregger A, etal., Sci Signal. 2015 Sep 8;8(393):ra90. doi: 10.1126/scisignal.aac6757.
11. RNF43 mutation is associated with aggressive tumor biology along with BRAF V600E mutation in right-sided colorectal cancer. Matsumoto A, etal., Oncol Rep. 2020 Jun;43(6):1853-1862. doi: 10.3892/or.2020.7561. Epub 2020 Mar 23.
12. RT-qPCR analysis of the tumor antigens TOMM34 and RNF43 in samples extracted from paraffin-embedded specimens of colorectal cancer. Matsushita N, etal., Oncol Lett. 2017 Aug;14(2):2281-2287. doi: 10.3892/ol.2017.6412. Epub 2017 Jun 19.
13. Dysregulated Wnt signalling and recurrent mutations of the tumour suppressor RNF43 in early gastric carcinogenesis. Min BH, etal., J Pathol. 2016 Nov;240(3):304-314. doi: 10.1002/path.4777.
14. Mutated Rnf43 Aggravates Helicobacter Pylori-Induced Gastric Pathology. Neumeyer V, etal., Cancers (Basel). 2019 Mar 16;11(3). pii: cancers11030372. doi: 10.3390/cancers11030372.
15. Loss of endogenous RNF43 function enhances proliferation and tumour growth of intestinal and gastric cells. Neumeyer V, etal., Carcinogenesis. 2019 Jun 10;40(4):551-559. doi: 10.1093/carcin/bgy152.
16. The complex world of WNT receptor signalling. Niehrs C Nat Rev Mol Cell Biol. 2012 Dec;13(12):767-79. doi: 10.1038/nrm3470. Epub 2012 Nov 15.
17. RNF43 Inhibits Cancer Cell Proliferation and Could be a Potential Prognostic Factor for Human Gastric Carcinoma. Niu L, etal., Cell Physiol Biochem. 2015;36(5):1835-46.
18. Phase I clinical trial of a novel peptide vaccine in combination with UFT/LV for metastatic colorectal cancer. Okuno K, etal., Exp Ther Med. 2011 Jan;2(1):73-79. doi: 10.3892/etm.2010.182. Epub 2010 Dec 2.
19. [Preliminary study of Peptide vaccine with UFT/LV as adjuvant setting for stage III colorectal cancer]. Okuno K, etal., Gan To Kagaku Ryoho. 2011 Nov;38(12):1906-8.
20. Exome sequencing of liver fluke-associated cholangiocarcinoma. Ong CK, etal., Nat Genet. 2012 May 6;44(6):690-3. doi: 10.1038/ng.2273.
21. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
22. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
23. Comprehensive gene review and curation RGD comprehensive gene curation
24. [Clinical study of Peptide-cocktail vaccination with tegafur-uracil/leucovorin for advanced colorectal cancer]. Sugiura F, etal., Gan To Kagaku Ryoho. 2012 Nov;39(12):1760-2.
25. Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development. Takeda H, etal., Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2057-65. doi: 10.1073/pnas.1603223113. Epub 2016 Mar 22.
26. Ring finger protein 43 expression is associated with genetic alteration status and poor prognosis among patients with intrahepatic cholangiocarcinoma. Talabnin C, etal., Hum Pathol. 2016 Jun;52:47-54. doi: 10.1016/j.humpath.2015.12.027. Epub 2016 Feb 1.
27. Wild-type APC Is Associated with Poor Survival in Metastatic Microsatellite Stable Colorectal Cancer. Wang C, etal., Oncologist. 2021 Mar;26(3):208-214. doi: 10.1002/onco.13607. Epub 2020 Dec 7.
28. Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer. Wang K, etal., Nat Genet. 2014 Jun;46(6):573-82. doi: 10.1038/ng.2983. Epub 2014 May 11.
29. Reduced Frequency and Prognostic Significance of Ring Finger Protein 43 Nucleotide Polymorphisms in a Chinese Colorectal Cancer Cohort. Wen D, etal., DNA Cell Biol. 2019 Jun;38(6):541-548. doi: 10.1089/dna.2019.4645. Epub 2019 May 28.
30. Downregulation of ring-finger protein 43 in glioma associates with poor prognosis. Xi S, etal., Int J Clin Exp Pathol. 2015 Jan 1;8(1):490-6. eCollection 2015.
31. Reversing effect of ring finger protein 43 inhibition on malignant phenotypes of human hepatocellular carcinoma. Xing C, etal., Mol Cancer Ther. 2013 Jan;12(1):94-103. doi: 10.1158/1535-7163.MCT-12-0672. Epub 2012 Nov 6.
32. Germline Profiling and Molecular Characterization of Early Onset Metastatic Colorectal Cancer. Xu T, etal., Front Oncol. 2020 Oct 19;10:568911. doi: 10.3389/fonc.2020.568911. eCollection 2020.
33. RNF43 ubiquitinates and degrades phosphorylated E-cadherin by c-Src to facilitate epithelial-mesenchymal transition in lung adenocarcinoma. Zhang Y, etal., BMC Cancer. 2019 Jul 8;19(1):670. doi: 10.1186/s12885-019-5880-1.
Additional References at PubMed
PMID:22575959   PMID:22895187  


Genomics

Comparative Map Data
Rnf43
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81072,958,744 - 73,034,540 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1072,961,641 - 73,034,551 (+)EnsemblGRCr8
mRatBN7.21072,461,508 - 72,537,301 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1072,464,348 - 72,536,977 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1077,076,871 - 77,146,437 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01076,581,783 - 76,651,384 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01072,046,299 - 72,115,890 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01074,956,411 - 75,028,951 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1074,959,285 - 75,028,951 (+)Ensemblrn6Rnor6.0
Rnor_5.01075,073,437 - 75,145,501 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41075,957,792 - 76,027,392 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1071,380,030 - 71,449,285 (+)NCBICelera
RGSC_v3.11075,970,268 - 76,041,762 (+)NCBI
Cytogenetic Map10q26NCBI
RNF43
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381758,352,500 - 58,417,534 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1758,353,676 - 58,417,735 (-)Ensemblhg38GRCh38
GRCh371756,429,861 - 56,494,895 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361753,786,036 - 53,849,893 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1752,892,826 - 52,956,720 (-)NCBICelera
Cytogenetic Map17q22NCBI
HuRef1751,791,664 - 51,855,538 (-)NCBIHuRef
CHM1_11756,496,051 - 56,559,939 (-)NCBICHM1_1
T2T-CHM13v2.01759,220,375 - 59,286,210 (-)NCBIT2T-CHM13v2.0
Rnf43
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391187,553,913 - 87,626,365 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1187,553,548 - 87,626,365 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381187,663,087 - 87,735,539 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1187,662,722 - 87,735,539 (+)Ensemblmm10GRCm38
MGSCv371187,476,589 - 87,549,041 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361187,516,092 - 87,551,733 (+)NCBIMGSCv36mm8
Celera1197,258,357 - 97,331,075 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1152.17NCBI
Rnf43
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554514,604,985 - 4,680,762 (+)Ensembl
ChiLan1.0NW_0049554514,604,985 - 4,680,762 (+)NCBIChiLan1.0ChiLan1.0
RNF43
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21974,524,931 - 74,588,376 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11779,336,108 - 79,399,545 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01752,420,516 - 52,492,813 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11757,276,761 - 57,347,748 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1757,276,761 - 57,347,748 (-)EnsemblpanPan2panpan1.1
RNF43
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1932,996,668 - 33,061,781 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl932,997,937 - 33,060,313 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha932,233,662 - 32,298,953 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0933,804,112 - 33,869,488 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl933,805,560 - 33,867,835 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1932,590,253 - 32,654,698 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0932,872,945 - 32,938,201 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0932,966,428 - 33,031,867 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rnf43
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560232,332,381 - 32,394,172 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364904,683,725 - 4,741,828 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364904,660,904 - 4,742,669 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF43
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1234,635,228 - 34,694,378 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11234,631,574 - 34,695,021 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21236,120,577 - 36,181,757 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF43
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11634,981,126 - 35,046,478 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1634,980,922 - 35,045,107 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660775,794,244 - 5,861,143 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf43
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624871191,546 - 259,120 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624871191,534 - 259,134 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Rnf43
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1983,062,792 - 83,136,020 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rnf43
385 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:38
Count of miRNA genes:35
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000010296
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105107189796071897Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103179628176796281Rat
631565Hcuc4Hepatic copper content QTL 44.15liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106743947373950209Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
8657410Bp374Blood pressure QTL 374heart left ventricle size trait (VT:0002753)heart left ventricle end-diastolic diameter (CMO:0000982)1067476608107713808Rat
152025224Bw193Body weight QTL 1936.47body mass (VT:0001259)105216243375582749Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063719161107713808Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)105686844076129113Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1058073360103073360Rat
12903252Cm113Cardiac mass QTL 1130.047heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105429633699451733Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1064939013107713808Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104183127886831278Rat
1579919Bp281Blood pressure QTL 2810.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105046480295464802Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104552916496099749Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104493935989939359Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1054296227107713808Rat
12903269Am15Aortic mass QTL 150.042aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105086028895860288Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102895035373950353Rat
12903266Cm114Cardiac mass QTL 1140.02heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1066817119107713808Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062556066107556066Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14282327487823274Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
12880372Am12Aortic mass QTL 120.003aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062556066107556066Rat
12880375Kidm66Kidney mass QTL 660.009kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106724133498502431Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104493935989939359Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
12880370Cm105Cardiac mass QTL 1050.008heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104282327487823274Rat
12880371Cm106Cardiac mass QTL 1060.007heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106184349698710773Rat
11565453Kidm58Kidney mass QTL 580.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1065390777107713808Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)106747660873695498Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2306792Ean4Experimental allergic neuritis QTL 44nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)104949549294495492Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1052269185107713808Rat
2317039Aia6Adjuvant induced arthritis QTL 64.31joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)106747660873695498Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
2298481Eau9Experimental allergic uveoretinitis QTL 90.0169uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)106413959783061459Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103550938380509383Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068920187107713808Rat
1358915Stresp7Stress response QTL 73.52blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)1065307813107713808Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1061843496106843496Rat
61402Niddm3Non-insulin dependent diabetes mellitus QTL 34.58blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)106184363383061236Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070698731107713808Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102907697874076978Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105530797293608131Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)1061843496100198886Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104360879388608793Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104994371094943710Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1066108888107555881Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103112911376129113Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104493935989939359Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1061843496100198886Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104786912992869129Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105060467795604677Rat
12880050Am10Aortic mass QTL 100.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)103950348784503487Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
634354Rends3Renal damage susceptibility QTL 30.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)1061997479106997479Rat
2301405Cm69Cardiac mass QTL 690.031heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat

Markers in Region
D10Chm6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21072,508,825 - 72,509,024 (+)MAPPERmRatBN7.2
Rnor_6.01076,556,439 - 76,556,637NCBIRnor6.0
Rnor_6.01075,001,953 - 75,002,151NCBIRnor6.0
Rnor_5.01075,100,237 - 75,100,435UniSTSRnor5.0
Rnor_5.01076,438,363 - 76,438,561UniSTSRnor5.0
RGSC_v3.41076,000,249 - 76,000,447UniSTSRGSC3.4
Celera1071,422,487 - 71,422,685UniSTS
Cytogenetic Map10q26UniSTS
D10Chm34  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21072,495,586 - 72,495,766 (+)MAPPERmRatBN7.2
Rnor_6.01074,988,717 - 74,988,896NCBIRnor6.0
Rnor_5.01075,113,491 - 75,113,671NCBIRnor5.0
RGSC_v3.41075,987,012 - 75,987,191UniSTSRGSC3.4
Celera1071,409,248 - 71,409,429UniSTS
Cytogenetic Map10q26UniSTS
D10Chm7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21072,506,089 - 72,506,294 (+)MAPPERmRatBN7.2
Rnor_6.01076,553,704 - 76,553,908NCBIRnor6.0
Rnor_6.01074,999,218 - 74,999,422NCBIRnor6.0
Rnor_5.01075,102,966 - 75,103,170UniSTSRnor5.0
Rnor_5.01076,435,628 - 76,435,832UniSTSRnor5.0
RGSC_v3.41075,997,514 - 75,997,718UniSTSRGSC3.4
Celera1071,419,752 - 71,419,956UniSTS
Cytogenetic Map10q26UniSTS
D10Chm16  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21072,469,183 - 72,469,453 (+)MAPPERmRatBN7.2
Rnor_6.01074,962,107 - 74,962,374NCBIRnor6.0
Rnor_5.01075,140,014 - 75,140,281UniSTSRnor5.0
RGSC_v3.41075,960,614 - 75,960,881UniSTSRGSC3.4
Celera1071,382,852 - 71,383,119UniSTS
Cytogenetic Map10q26UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 139 81 92 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000010296   ⟹   ENSRNOP00000010296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1072,963,416 - 73,034,551 (+)Ensembl
mRatBN7.2 Ensembl1072,466,362 - 72,536,977 (+)Ensembl
Rnor_6.0 Ensembl1074,959,285 - 75,028,951 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105746   ⟹   ENSRNOP00000095208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1072,961,641 - 73,034,551 (+)Ensembl
mRatBN7.2 Ensembl1072,464,348 - 72,536,977 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000127236   ⟹   ENSRNOP00000109995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1072,961,641 - 73,034,551 (+)Ensembl
RefSeq Acc Id: NM_001135921   ⟹   NP_001129393
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,963,366 - 73,034,540 (+)NCBI
mRatBN7.21072,466,113 - 72,537,301 (+)NCBI
Rnor_6.01074,959,285 - 75,028,951 (+)NCBI
Rnor_5.01075,073,437 - 75,145,501 (-)NCBI
RGSC_v3.41075,957,792 - 76,027,392 (+)RGD
Celera1071,380,030 - 71,449,285 (+)RGD
Sequence:
RefSeq Acc Id: XM_006247090   ⟹   XP_006247152
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,744 - 73,032,951 (+)NCBI
mRatBN7.21072,461,508 - 72,535,927 (+)NCBI
Rnor_6.01074,956,411 - 75,027,315 (+)NCBI
Rnor_5.01075,073,437 - 75,145,501 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006247091   ⟹   XP_006247153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,744 - 73,032,951 (+)NCBI
mRatBN7.21072,461,508 - 72,535,927 (+)NCBI
Rnor_6.01074,956,411 - 75,027,315 (+)NCBI
Rnor_5.01075,073,437 - 75,145,501 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006247094   ⟹   XP_006247156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81073,022,202 - 73,032,951 (+)NCBI
mRatBN7.21072,526,394 - 72,535,927 (+)NCBI
Rnor_6.01075,019,417 - 75,027,315 (+)NCBI
Rnor_5.01075,073,437 - 75,145,501 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008768041   ⟹   XP_008766263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81073,025,437 - 73,032,951 (+)NCBI
mRatBN7.21072,528,200 - 72,535,927 (+)NCBI
Rnor_6.01075,019,417 - 75,027,315 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039086050   ⟹   XP_038941978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,744 - 73,032,951 (+)NCBI
mRatBN7.21072,461,508 - 72,535,927 (+)NCBI
RefSeq Acc Id: XM_063269093   ⟹   XP_063125163
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,744 - 73,032,951 (+)NCBI
RefSeq Acc Id: XM_063269094   ⟹   XP_063125164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,749 - 73,034,540 (+)NCBI
RefSeq Acc Id: XM_063269095   ⟹   XP_063125165
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,749 - 73,034,540 (+)NCBI
RefSeq Acc Id: XM_063269096   ⟹   XP_063125166
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81072,958,749 - 73,034,540 (+)NCBI
RefSeq Acc Id: NP_001129393   ⟸   NM_001135921
- Peptide Label: precursor
- UniProtKB: A0A8I6AML0 (UniProtKB/TrEMBL),   A6HHU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247153   ⟸   XM_006247091
- Peptide Label: isoform X1
- UniProtKB: A6HHU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247152   ⟸   XM_006247090
- Peptide Label: isoform X1
- UniProtKB: A6HHU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006247156   ⟸   XM_006247094
- Peptide Label: isoform X3
- UniProtKB: D3ZP81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766263   ⟸   XM_008768041
- Peptide Label: isoform X3
- UniProtKB: D3ZP81 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010296   ⟸   ENSRNOT00000010296
RefSeq Acc Id: XP_038941978   ⟸   XM_039086050
- Peptide Label: isoform X1
- UniProtKB: A6HHU8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000095208   ⟸   ENSRNOT00000105746
RefSeq Acc Id: XP_063125163   ⟸   XM_063269093
- Peptide Label: isoform X1
- UniProtKB: A6HHU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125164   ⟸   XM_063269094
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AML0 (UniProtKB/TrEMBL),   A6HHU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125165   ⟸   XM_063269095
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AML0 (UniProtKB/TrEMBL),   A6HHU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125166   ⟸   XM_063269096
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AML0 (UniProtKB/TrEMBL),   A6HHU8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000109995   ⟸   ENSRNOT00000127236
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZP81-F1-model_v2 AlphaFold D3ZP81 1-782 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305204 AgrOrtholog
BioCyc Gene G2FUF-23749 BioCyc
Ensembl Genes ENSRNOG00000007606 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010296 ENTREZGENE
  ENSRNOT00000010296.7 UniProtKB/TrEMBL
  ENSRNOT00000105746 ENTREZGENE
  ENSRNOT00000105746.2 UniProtKB/TrEMBL
  ENSRNOT00000127236.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  3.50.30.30 UniProtKB/TrEMBL
InterPro RNF43_Znf_RING UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  ZNRF-3_ecto UniProtKB/TrEMBL
  ZNRF3_Arkadia_E3_ligases UniProtKB/TrEMBL
KEGG Report rno:303412 UniProtKB/TrEMBL
NCBI Gene 303412 ENTREZGENE
PANTHER RING ZINC FINGER UniProtKB/TrEMBL
Pfam zf-RING_2 UniProtKB/TrEMBL
  ZNRF_3_ecto UniProtKB/TrEMBL
PhenoGen Rnf43 PhenoGen
PROSITE ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007606 RatGTEx
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A8I6AML0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M5B2_RAT UniProtKB/TrEMBL
  A6HHU8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZP81 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Rnf43  ring finger protein 43   Rnf43_predicted  ring finger protein 43 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Rnf43_predicted  ring finger protein 43 (predicted)  RGD1305204_predicted  similar to hypothetical protein FLJ20315 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1305204_predicted  similar to hypothetical protein FLJ20315 (predicted)  LOC303412_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC303412_predicted  similar to hypothetical protein FLJ20315 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL