Gask1a (golgi associated kinase 1A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Gask1a (golgi associated kinase 1A) Rattus norvegicus
Analyze
Symbol: Gask1a
Name: golgi associated kinase 1A
RGD ID: 1305157
Description: Predicted to be located in endoplasmic reticulum and extracellular region. Predicted to be active in Golgi apparatus. Orthologous to human GASK1A (golgi associated kinase 1A); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fam198a; family with sequence similarity 198, member A; Golgi-associated kinase 1A; LOC316090; RGD1305157; similar to hypothetical basic protein I-19
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88130,488,279 - 130,521,242 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8130,488,354 - 130,521,242 (+)EnsemblGRCr8
mRatBN7.28121,610,779 - 121,643,742 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8121,610,787 - 121,642,942 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8127,202,332 - 127,238,573 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08125,401,409 - 125,437,644 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08123,231,119 - 123,264,497 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08130,581,072 - 130,614,118 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8130,581,062 - 130,612,510 (+)Ensemblrn6Rnor6.0
Rnor_5.08129,756,079 - 129,789,361 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48126,953,763 - 126,991,033 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8120,735,518 - 120,768,086 (+)NCBICelera
RGSC_v3.18126,977,122 - 127,007,592 (-)NCBI
Cytogenetic Map8q32NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:30188967  


Genomics

Comparative Map Data
Gask1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88130,488,279 - 130,521,242 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8130,488,354 - 130,521,242 (+)EnsemblGRCr8
mRatBN7.28121,610,779 - 121,643,742 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8121,610,787 - 121,642,942 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8127,202,332 - 127,238,573 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08125,401,409 - 125,437,644 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08123,231,119 - 123,264,497 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08130,581,072 - 130,614,118 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8130,581,062 - 130,612,510 (+)Ensemblrn6Rnor6.0
Rnor_5.08129,756,079 - 129,789,361 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48126,953,763 - 126,991,033 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8120,735,518 - 120,768,086 (+)NCBICelera
RGSC_v3.18126,977,122 - 127,007,592 (-)NCBI
Cytogenetic Map8q32NCBI
GASK1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38342,979,311 - 43,057,715 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl342,979,087 - 43,067,898 (+)Ensemblhg38GRCh38
GRCh37343,020,803 - 43,099,207 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36342,995,763 - 43,074,211 (+)NCBIBuild 36Build 36hg18NCBI36
Celera342,958,596 - 43,036,717 (+)NCBICelera
Cytogenetic Map3p22.1NCBI
HuRef343,063,911 - 43,142,036 (+)NCBIHuRef
CHM1_1342,970,704 - 43,048,832 (+)NCBICHM1_1
T2T-CHM13v2.0342,994,952 - 43,073,043 (+)NCBIT2T-CHM13v2.0
Gask1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399121,780,057 - 121,817,379 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9121,780,054 - 121,809,275 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm389121,950,988 - 121,988,313 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9121,950,988 - 121,980,209 (+)Ensemblmm10GRCm38
MGSCv379121,861,852 - 121,887,803 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369121,801,432 - 121,827,385 (+)NCBIMGSCv36mm8
Celera9122,428,461 - 122,453,585 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map972.76NCBI
Gask1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542027,901,885 - 27,952,998 (-)Ensembl
ChiLan1.0NW_00495542027,900,342 - 27,931,079 (-)NCBIChiLan1.0ChiLan1.0
GASK1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2242,902,830 - 43,025,371 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1342,907,592 - 43,035,181 (+)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl343,945,071 - 44,022,902 (+)EnsemblpanPan2panpan1.1
GASK1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12312,019,079 - 12,085,993 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2312,034,221 - 12,085,293 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2311,979,016 - 12,061,600 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02312,294,713 - 12,377,445 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2312,323,816 - 12,380,574 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12312,096,868 - 12,179,732 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02312,239,116 - 12,321,841 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02312,242,835 - 12,325,526 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gask1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118199,798,226 - 199,854,605 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366952,150,559 - 2,206,982 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366952,150,547 - 2,206,931 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GASK1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1326,415,710 - 26,473,645 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11326,415,637 - 26,473,649 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21329,168,962 - 29,181,652 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GASK1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1224,425,802 - 4,506,027 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl224,426,912 - 4,506,776 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041162,692,097 - 162,772,597 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gask1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473076,833,745 - 76,873,600 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473076,833,237 - 76,875,323 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Gask1a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v18113,122,519 - 113,139,986 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:152
Count of miRNA genes:122
Interacting mature miRNAs:134
Transcripts:ENSRNOT00000014323, ENSRNOT00000055866
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
RH129890  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28121,645,136 - 121,645,316 (+)MAPPERmRatBN7.2
Rnor_6.08130,615,513 - 130,615,692NCBIRnor6.0
Rnor_5.08129,790,756 - 129,790,935UniSTSRnor5.0
RGSC_v3.48126,954,254 - 126,954,433UniSTSRGSC3.4
Celera8120,769,481 - 120,769,660UniSTS
RH 3.4 Map81259.09UniSTS
Cytogenetic Map8q32UniSTS
RH131869  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28121,643,339 - 121,643,555 (+)MAPPERmRatBN7.2
Rnor_6.08130,613,716 - 130,613,931NCBIRnor6.0
Rnor_5.08129,788,959 - 129,789,174UniSTSRnor5.0
RGSC_v3.48126,956,015 - 126,956,230UniSTSRGSC3.4
Celera8120,767,684 - 120,767,899UniSTS
RH 3.4 Map81260.1UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 12 67 147 89 88 57 32 57 6 280 132 11 126 74 90 31 12 12

Sequence


Ensembl Acc Id: ENSRNOT00000014323   ⟹   ENSRNOP00000014323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8130,488,354 - 130,521,242 (+)Ensembl
mRatBN7.2 Ensembl8121,610,787 - 121,642,942 (+)Ensembl
Rnor_6.0 Ensembl8130,581,062 - 130,612,510 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115999   ⟹   ENSRNOP00000090742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8130,488,354 - 130,521,242 (+)Ensembl
mRatBN7.2 Ensembl8121,610,793 - 121,642,942 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000124212   ⟹   ENSRNOP00000101913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8130,496,631 - 130,521,242 (+)Ensembl
RefSeq Acc Id: NM_001399327   ⟹   NP_001386256
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88130,488,354 - 130,521,242 (+)NCBI
mRatBN7.28121,610,854 - 121,643,742 (+)NCBI
RefSeq Acc Id: XM_063265662   ⟹   XP_063121732
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88130,488,279 - 130,513,634 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001386256 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121732 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000014323
  ENSRNOP00000014323.7
  ENSRNOP00000090742.2
  ENSRNOP00000101913.1
Ensembl Acc Id: ENSRNOP00000014323   ⟸   ENSRNOT00000014323
Ensembl Acc Id: ENSRNOP00000090742   ⟸   ENSRNOT00000115999
RefSeq Acc Id: NP_001386256   ⟸   NM_001399327
- Peptide Label: precursor
- UniProtKB: F1M9D8 (UniProtKB/TrEMBL),   A0A8I6AAQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121732   ⟸   XM_063265662
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000101913   ⟸   ENSRNOT00000124212

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M9D8-F1-model_v2 AlphaFold F1M9D8 1-564 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305157 AgrOrtholog
BioCyc Gene G2FUF-28671 BioCyc
Ensembl Genes ENSRNOG00000025676 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014323 ENTREZGENE
  ENSRNOT00000014323.9 UniProtKB/TrEMBL
  ENSRNOT00000115999.2 UniProtKB/TrEMBL
  ENSRNOT00000124212.1 UniProtKB/TrEMBL
InterPro FAM198 UniProtKB/TrEMBL
NCBI Gene 316090 ENTREZGENE
PANTHER GOLGI-ASSOCIATED KINASE 1A UniProtKB/TrEMBL
  PTHR15905 UniProtKB/TrEMBL
Pfam FAM198 UniProtKB/TrEMBL
PhenoGen Gask1a PhenoGen
RatGTEx ENSRNOG00000025676 RatGTEx
UniProt A0A8I6AAQ5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LG90_RAT UniProtKB/TrEMBL
  F1M9D8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-10-30 Gask1a  golgi associated kinase 1A  Fam198a  family with sequence similarity 198, member A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-02-12 Fam198a  family with sequence similarity 198, member A  RGD1305157  similar to hypothetical basic protein I-19   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1305157  similar to hypothetical basic protein I-19   RGD1305157_predicted  similar to hypothetical basic protein I-19 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1305157_predicted  similar to hypothetical basic protein I-19 (predicted)  LOC316090_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC316090_predicted  similar to hypothetical basic protein I-19 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL