Ctnna2 (catenin alpha 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Ctnna2 (catenin alpha 2) Rattus norvegicus
Analyze
Symbol: Ctnna2
Name: catenin alpha 2
RGD ID: 1305060
Description: Predicted to enable actin filament binding activity; beta-catenin binding activity; and identical protein binding activity. Predicted to be involved in several processes, including modification of postsynaptic actin cytoskeleton; negative regulation of Arp2/3 complex-mediated actin nucleation; and nervous system development. Predicted to be located in several cellular components, including basolateral plasma membrane; lamellipodium; and postsynaptic density. Predicted to be part of catenin complex. Predicted to be active in several cellular components, including hippocampal mossy fiber to CA3 synapse; parallel fiber to Purkinje cell synapse; and postsynaptic density, intracellular component. Predicted to be extrinsic component of postsynaptic membrane and extrinsic component of presynaptic membrane. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations. Orthologous to human CTNNA2 (catenin alpha 2); PARTICIPATES IN arrhythmogenic right ventricular cardiomyopathy pathway; endometrial cancer pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: catenin (cadherin associated protein), alpha 2; catenin alpha-2; catenin, alpha 2; Catna2; LOC297357
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84110,852,265 - 112,001,351 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4110,852,265 - 112,001,365 (-)EnsemblGRCr8
mRatBN7.24109,294,249 - 110,443,409 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4109,293,978 - 110,443,522 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4114,699,509 - 115,849,021 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04110,474,640 - 111,624,120 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04109,094,817 - 110,244,312 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04107,880,611 - 109,042,724 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4107,881,826 - 108,008,484 (-)Ensemblrn6Rnor6.0
Rnor_5.04172,586,790 - 173,745,983 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44110,747,551 - 111,922,482 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera498,339,981 - 99,476,551 (-)NCBICelera
RGSC_v3.14111,016,614 - 112,035,932 (-)NCBI
Cytogenetic Map4q33NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8909549   PMID:9950951   PMID:12089526   PMID:12123610   PMID:12695331   PMID:14657280   PMID:15034585   PMID:15630473   PMID:16182284   PMID:16457793   PMID:16691566   PMID:17114649  
PMID:19129494   PMID:23417122   PMID:25468996   PMID:30013181  


Genomics

Comparative Map Data
Ctnna2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84110,852,265 - 112,001,351 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4110,852,265 - 112,001,365 (-)EnsemblGRCr8
mRatBN7.24109,294,249 - 110,443,409 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4109,293,978 - 110,443,522 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4114,699,509 - 115,849,021 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04110,474,640 - 111,624,120 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04109,094,817 - 110,244,312 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04107,880,611 - 109,042,724 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4107,881,826 - 108,008,484 (-)Ensemblrn6Rnor6.0
Rnor_5.04172,586,790 - 173,745,983 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44110,747,551 - 111,922,482 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera498,339,981 - 99,476,551 (-)NCBICelera
RGSC_v3.14111,016,614 - 112,035,932 (-)NCBI
Cytogenetic Map4q33NCBI
CTNNA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38279,185,377 - 80,648,780 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl279,185,231 - 80,648,861 (+)Ensemblhg38GRCh38
GRCh37279,412,503 - 80,875,905 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36279,593,634 - 80,729,416 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34279,651,780 - 80,787,562NCBI
Celera279,568,796 - 80,704,725 (+)NCBICelera
Cytogenetic Map2p12NCBI
HuRef279,475,616 - 80,610,857 (+)NCBIHuRef
CHM1_1279,669,347 - 80,805,984 (+)NCBICHM1_1
T2T-CHM13v2.0279,185,703 - 80,649,017 (+)NCBIT2T-CHM13v2.0
Ctnna2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39676,858,620 - 77,956,798 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl676,858,620 - 77,956,682 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38676,881,637 - 77,979,815 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl676,881,637 - 77,979,699 (-)Ensemblmm10GRCm38
MGSCv37676,831,631 - 77,929,661 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36676,811,161 - 77,909,097 (-)NCBIMGSCv36mm8
Celera678,902,485 - 80,006,681 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map633.54NCBI
Ctnna2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554245,986,073 - 6,911,826 (-)Ensembl
ChiLan1.0NW_0049554245,985,170 - 7,055,830 (-)NCBIChiLan1.0ChiLan1.0
CTNNA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21245,694,150 - 46,845,852 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A45,696,905 - 46,848,605 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A79,594,694 - 80,745,885 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A81,158,206 - 82,308,244 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A81,303,559 - 82,307,258 (+)EnsemblpanPan2panpan1.1
CTNNA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11743,472,346 - 44,504,881 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1743,472,923 - 44,557,766 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1743,168,024 - 44,195,314 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01744,284,748 - 45,372,518 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1744,285,152 - 45,372,443 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11743,368,220 - 44,455,587 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01743,410,252 - 44,491,113 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01743,907,412 - 44,995,361 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ctnna2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244062924,466,584 - 5,532,415 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365565,205,481 - 6,271,304 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTNNA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl363,205,084 - 63,455,471 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1363,205,073 - 64,417,990 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2366,285,690 - 66,567,714 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CTNNA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11426,579,012 - 27,729,581 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1426,578,896 - 26,836,423 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604584,556,698 - 85,727,504 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctnna2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474922,333,710 - 23,412,593 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474922,332,750 - 23,546,165 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ctnna2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1668,377,281 - 69,461,297 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ctnna2
10009 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:109
Count of miRNA genes:86
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000007971
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)496731383141731383Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486583980149763391Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)492406430137406430Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)480212111119233320Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4108206096153206096Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)471647492116647492Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4111383604156383604Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)465060960127749483Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)451085655113588029Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)488883695133883695Rat
2317588Eae27Experimental allergic encephalomyelitis QTL 27nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)469036742114036742Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4103834277148834277Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)488883695133883695Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4107346299152346299Rat
2306547Iddm38Insulin dependent diabetes mellitus QTL 38blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)468353567113353567Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
2306545Iddm39Insulin dependent diabetes mellitus QTL 39blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478687630123687630Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4111383604156383604Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)474169813134199155Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)486058928131411333Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)484349032129349032Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)482336765127336765Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)486583980131583980Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat

Markers in Region
D4Mit28  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24110,275,411 - 110,275,633 (+)MAPPERmRatBN7.2
Rnor_6.04108,876,717 - 108,876,936NCBIRnor6.0
Rnor_5.04173,580,126 - 173,580,345UniSTSRnor5.0
RGSC_v3.44111,754,988 - 111,755,208RGDRGSC3.4
RGSC_v3.44111,754,989 - 111,755,208UniSTSRGSC3.4
Celera499,317,592 - 99,317,811UniSTS
RGSC_v3.14111,999,469 - 111,999,689RGD
Cytogenetic Map4q33UniSTS
D4Rat97  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24109,588,035 - 109,588,254 (+)MAPPERmRatBN7.2
Rnor_6.04108,186,335 - 108,186,553NCBIRnor6.0
Rnor_5.04172,891,980 - 172,892,198UniSTSRnor5.0
RGSC_v3.44111,052,091 - 111,052,309UniSTSRGSC3.4
RGSC_v3.44111,052,067 - 111,052,383RGDRGSC3.4
Celera498,632,058 - 98,632,276UniSTS
RGSC_v3.14111,296,572 - 111,296,790RGD
RH 3.4 Map5748.99RGD
RH 3.4 Map5748.99UniSTS
RH 2.0 Map5689.7RGD
SHRSP x BN Map449.91RGD
Cytogenetic Map4q33UniSTS
D10Got117  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24110,341,308 - 110,341,478 (+)MAPPERmRatBN7.2
Rnor_6.04108,940,816 - 108,940,985NCBIRnor6.0
Rnor_5.04173,644,225 - 173,644,394UniSTSRnor5.0
RGSC_v3.44111,820,080 - 111,820,250RGDRGSC3.4
RGSC_v3.44111,820,081 - 111,820,250UniSTSRGSC3.4
Celera499,375,124 - 99,375,293UniSTS
RGSC_v3.14112,064,562 - 112,064,731RGD
RH 3.4 Map10738.5UniSTS
RH 3.4 Map10738.5RGD
RH 2.0 Map10911.9RGD
Cytogenetic Map4q33UniSTS
D4Got218  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24109,443,598 - 109,443,868 (+)MAPPERmRatBN7.2
Rnor_6.04108,041,147 - 108,041,416NCBIRnor6.0
Rnor_5.04172,747,084 - 172,747,353UniSTSRnor5.0
RGSC_v3.44110,904,250 - 110,904,519UniSTSRGSC3.4
Celera498,488,573 - 98,488,842UniSTS
Cytogenetic Map4q33UniSTS
RH130885  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24109,894,954 - 109,895,172 (+)MAPPERmRatBN7.2
Rnor_6.04108,494,886 - 108,495,103NCBIRnor6.0
Rnor_5.04173,200,945 - 173,201,162UniSTSRnor5.0
RGSC_v3.44111,365,154 - 111,365,371UniSTSRGSC3.4
Celera498,938,638 - 98,938,855UniSTS
Cytogenetic Map4q33UniSTS
RH132643  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24109,294,322 - 109,294,514 (+)MAPPERmRatBN7.2
Rnor_6.04107,880,956 - 107,881,147NCBIRnor6.0
Rnor_5.04172,587,135 - 172,587,326UniSTSRnor5.0
RGSC_v3.44110,749,211 - 110,749,402UniSTSRGSC3.4
Celera498,340,326 - 98,340,517UniSTS
RH 3.4 Map4656.73UniSTS
Cytogenetic Map4q33UniSTS
AU049796  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24110,133,169 - 110,133,447 (+)MAPPERmRatBN7.2
Rnor_6.04108,733,001 - 108,733,278NCBIRnor6.0
Rnor_5.04173,437,188 - 173,437,465UniSTSRnor5.0
RGSC_v3.44111,609,376 - 111,609,653UniSTSRGSC3.4
Celera499,175,282 - 99,175,559UniSTS
Cytogenetic Map4q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 10 60 150 86 85 54 39 54 5 238 122 4 133 39 89 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000007971   ⟹   ENSRNOP00000007972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4110,852,265 - 111,941,029 (-)Ensembl
mRatBN7.2 Ensembl4109,294,842 - 110,443,522 (-)Ensembl
Rnor_6.0 Ensembl4107,881,826 - 108,008,484 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080999   ⟹   ENSRNOP00000070637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4110,852,265 - 112,001,365 (-)Ensembl
mRatBN7.2 Ensembl4109,293,978 - 110,443,522 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085062   ⟹   ENSRNOP00000070468
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4111,613,953 - 111,941,029 (-)Ensembl
mRatBN7.2 Ensembl4110,055,690 - 110,443,522 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000121536   ⟹   ENSRNOP00000109158
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4110,852,265 - 112,001,302 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000138941   ⟹   ENSRNOP00000107505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4110,852,265 - 111,775,981 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000161466   ⟹   ENSRNOP00000109622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4110,852,265 - 112,001,302 (-)Ensembl
RefSeq Acc Id: NM_001106598   ⟹   NP_001100068
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84110,852,265 - 112,001,351 (-)NCBI
mRatBN7.24109,294,249 - 110,443,335 (-)NCBI
Rnor_6.04107,880,611 - 109,042,663 (-)NCBI
Rnor_5.04172,586,790 - 173,745,983 (-)NCBI
RGSC_v3.44110,747,551 - 111,922,482 (-)RGD
Celera498,339,981 - 99,476,551 (-)RGD
Sequence:
RefSeq Acc Id: NM_001415842   ⟹   NP_001402771
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84110,852,265 - 112,001,351 (-)NCBI
mRatBN7.24109,294,249 - 110,443,335 (-)NCBI
RefSeq Acc Id: NM_001415843   ⟹   NP_001402772
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84110,852,265 - 112,001,351 (-)NCBI
mRatBN7.24109,294,249 - 110,443,335 (-)NCBI
RefSeq Acc Id: XM_017592545   ⟹   XP_017448034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84110,852,265 - 112,001,205 (-)NCBI
mRatBN7.24109,295,193 - 110,443,409 (-)NCBI
Rnor_6.04107,880,882 - 109,042,724 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063285787   ⟹   XP_063141857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84110,852,265 - 112,001,305 (-)NCBI
RefSeq Acc Id: NP_001100068   ⟸   NM_001106598
- Peptide Label: isoform 1
- UniProtKB: A6IAF1 (UniProtKB/TrEMBL),   A0A0G2JYF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448034   ⟸   XM_017592545
- Peptide Label: isoform X1
- UniProtKB: A6IAF1 (UniProtKB/TrEMBL),   A0A0G2JYF7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000007972   ⟸   ENSRNOT00000007971
Ensembl Acc Id: ENSRNOP00000070637   ⟸   ENSRNOT00000080999
Ensembl Acc Id: ENSRNOP00000070468   ⟸   ENSRNOT00000085062
RefSeq Acc Id: NP_001402771   ⟸   NM_001415842
- Peptide Label: isoform 2
- UniProtKB: A6IAF0 (UniProtKB/TrEMBL),   D4A6H8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001402772   ⟸   NM_001415843
- Peptide Label: isoform 1
- UniProtKB: A6IAF1 (UniProtKB/TrEMBL),   A0A0G2JYF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141857   ⟸   XM_063285787
- Peptide Label: isoform X2
- UniProtKB: A6IAF0 (UniProtKB/TrEMBL),   D4A6H8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000109158   ⟸   ENSRNOT00000121536
Ensembl Acc Id: ENSRNOP00000107505   ⟸   ENSRNOT00000138941
Ensembl Acc Id: ENSRNOP00000109622   ⟸   ENSRNOT00000161466

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A6H8-F1-model_v2 AlphaFold D4A6H8 1-476 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305060 AgrOrtholog
BioCyc Gene G2FUF-44092 BioCyc
Ensembl Genes ENSRNOG00000006003 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007971 ENTREZGENE
  ENSRNOT00000007971.9 UniProtKB/TrEMBL
  ENSRNOT00000080999 ENTREZGENE
  ENSRNOT00000080999.3 UniProtKB/TrEMBL
  ENSRNOT00000085062.3 UniProtKB/TrEMBL
  ENSRNOT00000121536.1 UniProtKB/TrEMBL
  ENSRNOT00000138941 ENTREZGENE
  ENSRNOT00000138941.1 UniProtKB/TrEMBL
  ENSRNOT00000161466 ENTREZGENE
  ENSRNOT00000161466.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.250.2510 UniProtKB/TrEMBL
  Alpha-catenin/vinculin-like UniProtKB/TrEMBL
InterPro Alpha-catenin/vinculin-like_sf UniProtKB/TrEMBL
  Alpha_catenin UniProtKB/TrEMBL
  Vinculin/catenin UniProtKB/TrEMBL
  Vinculin_CS UniProtKB/TrEMBL
KEGG Report rno:297357 UniProtKB/TrEMBL
NCBI Gene 297357 ENTREZGENE
PANTHER ALPHA CATENIN UniProtKB/TrEMBL
  PTHR18914:SF23 UniProtKB/TrEMBL
Pfam Vinculin UniProtKB/TrEMBL
PhenoGen Ctnna2 PhenoGen
PRINTS ALPHACATENIN UniProtKB/TrEMBL
PROSITE VINCULIN_1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006003 RatGTEx
Superfamily-SCOP Vinculin/catenin UniProtKB/TrEMBL
UniProt A0A0G2JY03_RAT UniProtKB/TrEMBL
  A0A0G2JYF7 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LEF9_RAT UniProtKB/TrEMBL
  A0ABK0LFY4_RAT UniProtKB/TrEMBL
  A0ABK0M208_RAT UniProtKB/TrEMBL
  A6IAF0 ENTREZGENE, UniProtKB/TrEMBL
  A6IAF1 ENTREZGENE, UniProtKB/TrEMBL
  D4A6H8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Ctnna2  catenin alpha 2  Ctnna2  catenin (cadherin associated protein), alpha 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ctnna2  catenin (cadherin associated protein), alpha 2   Ctnna2_predicted  catenin (cadherin associated protein), alpha 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Ctnna2_predicted  catenin (cadherin associated protein), alpha 2 (predicted)  Catna2_predicted  catenin alpha 2 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Catna2_predicted  catenin alpha 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED