Mmaa (metabolism of cobalamin associated A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Mmaa (metabolism of cobalamin associated A) Rattus norvegicus
Analyze
Symbol: Mmaa
Name: metabolism of cobalamin associated A
RGD ID: 1305035
Description: Predicted to enable GTP binding activity; GTPase activity; and protein homodimerization activity. Predicted to be involved in cobalamin metabolic process. Predicted to act upstream of or within succinyl-CoA biosynthetic process. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in methylmalonic acidemia cblA type. Orthologous to human MMAA (metabolism of cobalamin associated A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC291939; methylmalonic aciduria (cobalamin deficiency) cblA type; methylmalonic aciduria (cobalamin deficiency) type A; methylmalonic aciduria type A protein, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81945,523,352 - 45,553,602 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1945,523,379 - 45,555,375 (+)EnsemblGRCr8
mRatBN7.21928,619,060 - 28,649,319 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1928,619,087 - 28,649,319 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1935,474,544 - 35,504,160 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01936,128,620 - 36,158,234 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01938,364,327 - 38,393,832 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01932,294,087 - 32,325,927 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1932,308,236 - 32,325,927 (+)Ensemblrn6Rnor6.0
Rnor_5.01943,190,826 - 43,222,204 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41930,455,554 - 30,487,154 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1928,128,651 - 28,159,788 (+)NCBICelera
RGSC_v3.11930,474,283 - 30,490,378 (+)NCBI
Cytogenetic Map19q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,ISO)
cytosol  (ISO)
mitochondrion  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Mutations in the MMAA gene in patients with the cblA disorder of vitamin B12 metabolism. Lerner-Ellis JP, etal., Hum Mutat. 2004 Dec;24(6):509-16.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:20876572   PMID:28497574   PMID:31056463  


Genomics

Comparative Map Data
Mmaa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81945,523,352 - 45,553,602 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1945,523,379 - 45,555,375 (+)EnsemblGRCr8
mRatBN7.21928,619,060 - 28,649,319 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1928,619,087 - 28,649,319 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1935,474,544 - 35,504,160 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01936,128,620 - 36,158,234 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01938,364,327 - 38,393,832 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01932,294,087 - 32,325,927 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1932,308,236 - 32,325,927 (+)Ensemblrn6Rnor6.0
Rnor_5.01943,190,826 - 43,222,204 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41930,455,554 - 30,487,154 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1928,128,651 - 28,159,788 (+)NCBICelera
RGSC_v3.11930,474,283 - 30,490,378 (+)NCBI
Cytogenetic Map19q11NCBI
MMAA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384145,619,385 - 145,660,033 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4145,599,042 - 145,660,033 (+)Ensemblhg38GRCh38
GRCh374146,540,537 - 146,581,185 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364146,779,677 - 146,796,187 (+)NCBIBuild 36Build 36hg18NCBI36
Build 344146,917,831 - 146,934,342NCBI
Celera4143,868,075 - 143,908,722 (+)NCBICelera
Cytogenetic Map4q31.21NCBI
HuRef4142,270,497 - 142,311,145 (+)NCBIHuRef
CHM1_14146,517,133 - 146,557,773 (+)NCBICHM1_1
T2T-CHM13v2.04148,935,202 - 148,975,850 (+)NCBIT2T-CHM13v2.0
Mmaa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39879,990,226 - 80,021,637 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl879,990,227 - 80,021,566 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38879,263,597 - 79,295,002 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl879,263,598 - 79,294,937 (-)Ensemblmm10GRCm38
MGSCv37881,790,323 - 81,818,855 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36882,162,496 - 82,191,009 (-)NCBIMGSCv36mm8
Celera883,543,391 - 83,571,923 (-)NCBICelera
Cytogenetic Map8C1NCBI
cM Map837.51NCBI
Mmaa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554281,473,898 - 1,489,665 (+)Ensembl
ChiLan1.0NW_0049554281,465,118 - 1,489,332 (+)NCBIChiLan1.0ChiLan1.0
MMAA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23143,491,406 - 143,536,113 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14143,857,581 - 143,901,095 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04137,960,877 - 138,001,384 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14149,620,309 - 149,658,476 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4149,620,381 - 149,658,470 (+)EnsemblpanPan2panpan1.1
MMAA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11544,221,082 - 44,243,530 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1544,220,934 - 44,241,101 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1544,613,175 - 44,636,041 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01544,889,029 - 44,911,731 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1544,889,055 - 44,913,640 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11544,162,432 - 44,185,204 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01544,249,533 - 44,272,215 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01544,514,450 - 44,537,173 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mmaa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530146,074,045 - 46,100,714 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365353,511,349 - 3,525,507 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365353,511,389 - 3,538,038 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100523624
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl882,802,287 - 82,829,975 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1 Ensembl882,834,595 - 82,864,828 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1882,765,074 - 82,864,829 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2888,144,860 - 88,168,941 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MMAA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1792,180,963 - 92,218,068 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl792,201,805 - 92,220,163 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603771,831,219 - 71,869,704 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mmaa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248534,552,266 - 4,570,413 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248534,546,959 - 4,565,880 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Mmaa
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11720,810,866 - 20,840,221 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mmaa
143 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:495
Count of miRNA genes:246
Interacting mature miRNAs:310
Transcripts:ENSRNOT00000015508
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
61328Eae8Experimental allergic encephalomyelitis QTL 84nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)194172060949971820Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)194072709254856850Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)193009938347207961Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)194072709254856850Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)194072709254856850Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000015508   ⟹   ENSRNOP00000015508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1945,523,379 - 45,555,375 (+)Ensembl
mRatBN7.2 Ensembl1928,619,087 - 28,649,319 (+)Ensembl
Rnor_6.0 Ensembl1932,308,236 - 32,325,927 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000143506   ⟹   ENSRNOP00000106993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1945,523,409 - 45,554,577 (+)Ensembl
RefSeq Acc Id: NM_001389261   ⟹   NP_001376190
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81945,523,352 - 45,553,602 (+)NCBI
mRatBN7.21928,619,060 - 28,649,314 (+)NCBI
RefSeq Acc Id: XM_017601211   ⟹   XP_017456700
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81945,523,369 - 45,553,602 (+)NCBI
mRatBN7.21928,619,077 - 28,649,319 (+)NCBI
Rnor_6.01932,294,087 - 32,324,337 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097580   ⟹   XP_038953508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81945,523,415 - 45,553,602 (+)NCBI
mRatBN7.21928,619,136 - 28,649,319 (+)NCBI
RefSeq Acc Id: XM_039097581   ⟹   XP_038953509
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81945,531,148 - 45,553,602 (+)NCBI
mRatBN7.21928,626,895 - 28,649,319 (+)NCBI
RefSeq Acc Id: XM_039097582   ⟹   XP_038953510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81945,537,842 - 45,553,602 (+)NCBI
mRatBN7.21928,633,550 - 28,649,319 (+)NCBI
RefSeq Acc Id: XM_039097584   ⟹   XP_038953512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81945,541,589 - 45,553,602 (+)NCBI
mRatBN7.21928,637,299 - 28,649,319 (+)NCBI
RefSeq Acc Id: XM_063277878   ⟹   XP_063133948
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81945,523,415 - 45,553,602 (+)NCBI
RefSeq Acc Id: XM_063277879   ⟹   XP_063133949
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81945,523,415 - 45,553,602 (+)NCBI
RefSeq Acc Id: XP_017456700   ⟸   XM_017601211
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000015508   ⟸   ENSRNOT00000015508
RefSeq Acc Id: NP_001376190   ⟸   NM_001389261
- UniProtKB: D3ZNY3 (UniProtKB/TrEMBL),   A6IYI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953508   ⟸   XM_039097580
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953509   ⟸   XM_039097581
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953510   ⟸   XM_039097582
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038953512   ⟸   XM_039097584
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063133948   ⟸   XM_063277878
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063133949   ⟸   XM_063277879
- Peptide Label: isoform X2
- UniProtKB: A6IYI5 (UniProtKB/TrEMBL),   D3ZNY3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000106993   ⟸   ENSRNOT00000143506
Protein Domains
AAA+ ATPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZNY3-F1-model_v2 AlphaFold D3ZNY3 1-415 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305035 AgrOrtholog
BioCyc Gene G2FUF-5947 BioCyc
Ensembl Genes ENSRNOG00000011618 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015508 ENTREZGENE
  ENSRNOT00000015508.7 UniProtKB/TrEMBL
  ENSRNOT00000143506 ENTREZGENE
  ENSRNOT00000143506.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.130 UniProtKB/TrEMBL
  1.20.5.170 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro ArgK UniProtKB/TrEMBL
  ATPase_AAA+_core UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene 291939 ENTREZGENE
PANTHER METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR23408 UniProtKB/TrEMBL
Pfam MeaB UniProtKB/TrEMBL
PhenoGen Mmaa PhenoGen
RatGTEx ENSRNOG00000011618 RatGTEx
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0ABK0LT57_RAT UniProtKB/TrEMBL
  A6IYI5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZNY3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-08-15 Mmaa  metabolism of cobalamin associated A  Mmaa  methylmalonic aciduria (cobalamin deficiency) cblA type  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Mmaa  methylmalonic aciduria (cobalamin deficiency) cblA type  Mmaa_predicted  methylmalonic aciduria (cobalamin deficiency) cblA type (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Mmaa_predicted  methylmalonic aciduria (cobalamin deficiency) cblA type (predicted)    methylmalonic aciduria (cobalamin deficiency) type A (predicted)  Name updated 1299863 APPROVED
2005-01-12 Mmaa_predicted  methylmalonic aciduria (cobalamin deficiency) type A (predicted)      Symbol and Name status set to approved 70820 APPROVED