Hipk1 (homeodomain interacting protein kinase 1) - Rat Genome Database

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Gene: Hipk1 (homeodomain interacting protein kinase 1) Rattus norvegicus
Analyze
Symbol: Hipk1
Name: homeodomain interacting protein kinase 1
RGD ID: 1304941
Description: Predicted to enable protein serine/threonine kinase activity and protein tyrosine kinase activity. Predicted to be involved in several processes, including apoptotic signaling pathway; camera-type eye morphogenesis; and endothelial cell apoptotic process. Predicted to act upstream of or within anterior/posterior pattern specification and positive regulation of cell population proliferation. Predicted to be located in centrosome; cytosol; and nuclear speck. Predicted to be active in PML body and cytoplasm. Orthologous to human HIPK1 (homeodomain interacting protein kinase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: homeodomain-interacting protein kinase 1; LOC365895
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82193,937,261 - 193,988,247 (-)NCBIGRCr8
mRatBN7.22191,248,817 - 191,299,787 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2191,248,817 - 191,298,902 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2198,845,877 - 198,895,860 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02196,718,605 - 196,768,588 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02191,535,577 - 191,585,560 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02206,224,015 - 206,274,910 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2206,224,015 - 206,274,079 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02225,647,725 - 225,698,674 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42198,963,076 - 199,014,710 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12198,929,617 - 198,977,395 (-)NCBI
Celera2183,720,653 - 183,770,661 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (IEA,ISO)
cytoplasm  (IBA,ISO)
cytosol  (IEA,ISO)
nuclear speck  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (IBA,ISO)
PML body  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12529400   PMID:12702766   PMID:15701637   PMID:16537918   PMID:20579985   PMID:23565059   PMID:24559171   PMID:28289210   PMID:30361391  


Genomics

Comparative Map Data
Hipk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82193,937,261 - 193,988,247 (-)NCBIGRCr8
mRatBN7.22191,248,817 - 191,299,787 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2191,248,817 - 191,298,902 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2198,845,877 - 198,895,860 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02196,718,605 - 196,768,588 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02191,535,577 - 191,585,560 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02206,224,015 - 206,274,910 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2206,224,015 - 206,274,079 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02225,647,725 - 225,698,674 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42198,963,076 - 199,014,710 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12198,929,617 - 198,977,395 (-)NCBI
Celera2183,720,653 - 183,770,661 (-)NCBICelera
Cytogenetic Map2q34NCBI
HIPK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381113,929,324 - 113,977,869 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1113,929,324 - 113,977,869 (+)EnsemblGRCh38hg38GRCh38
GRCh371114,471,946 - 114,520,491 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361114,273,519 - 114,321,945 (+)NCBINCBI36Build 36hg18NCBI36
Celera1112,701,213 - 112,749,655 (+)NCBICelera
Cytogenetic Map1p13.2NCBI
HuRef1112,330,056 - 112,378,556 (+)NCBIHuRef
CHM1_11114,586,835 - 114,635,335 (+)NCBICHM1_1
T2T-CHM13v2.01113,940,985 - 113,989,530 (+)NCBIT2T-CHM13v2.0
Hipk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393103,647,131 - 103,699,210 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3103,647,131 - 103,698,879 (-)EnsemblGRCm39 Ensembl
GRCm383103,739,815 - 103,791,894 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3103,739,815 - 103,791,563 (-)EnsemblGRCm38mm10GRCm38
MGSCv373103,543,738 - 103,595,198 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363103,872,732 - 103,920,240 (-)NCBIMGSCv36mm8
MGSCv363103,853,833 - 103,900,424 (-)NCBIMGSCv36mm8
Celera3105,941,903 - 105,994,105 (-)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map345.52NCBI
Hipk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543517,172,651 - 17,257,371 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543517,201,866 - 17,257,371 (+)NCBIChiLan1.0ChiLan1.0
HIPK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21106,587,929 - 106,636,756 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11106,181,332 - 106,230,139 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0188,579,603 - 88,627,988 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11123,629,271 - 123,677,714 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1123,633,134 - 123,677,714 (-)Ensemblpanpan1.1panPan2
HIPK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11751,732,079 - 51,783,534 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1751,732,016 - 51,781,063 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1751,383,446 - 51,434,833 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01752,610,377 - 52,661,859 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1752,610,173 - 52,661,830 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11751,617,630 - 51,668,969 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01751,685,923 - 51,737,304 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01752,258,450 - 52,309,908 (+)NCBIUU_Cfam_GSD_1.0
Hipk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505815,124,279 - 15,211,810 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366902,265,849 - 2,353,485 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_0049366902,265,849 - 2,274,199 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366902,293,740 - 2,353,450 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HIPK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4106,572,755 - 106,627,418 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14106,570,950 - 106,627,114 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24116,708,471 - 116,742,456 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HIPK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12019,680,952 - 19,731,503 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2019,680,778 - 19,730,129 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603822,451,246 - 22,500,359 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hipk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247729,579,488 - 9,658,881 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hipk1
123 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1419
Count of miRNA genes:353
Interacting mature miRNAs:505
Transcripts:ENSRNOT00000056079
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
61458Bp10Blood pressure QTL 103.42arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2122609194206936711Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
10043139Iddm55Insulin dependent diabetes mellitus QTL 553.10.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2190602746192625452Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
4889834Pur24Proteinuria QTL 245.80.014urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)2184114274202447032Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2185876309219753474Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1298083Bp158Blood pressure QTL 1582.62arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1331745Bp203Blood pressure QTL 2034.377arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2189599258218414891Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2179335906224335906Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
7488929Bp366Blood pressure QTL 3660.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2184974550193094998Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
2293084Iddm26Insulin dependent diabetes mellitus QTL 262.9blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2174930955213594495Rat

Markers in Region
RH139604  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22191,249,331 - 191,249,540 (+)MAPPERmRatBN7.2
Rnor_6.02206,224,530 - 206,224,738NCBIRnor6.0
Rnor_5.02225,648,240 - 225,648,448UniSTSRnor5.0
RGSC_v3.42198,963,591 - 198,963,799UniSTSRGSC3.4
Celera2183,721,168 - 183,721,376UniSTS
RH 3.4 Map21326.6UniSTS
Cytogenetic Map2q34UniSTS
SHGC-16738  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22191,248,825 - 191,248,972 (+)MAPPERmRatBN7.2
Rnor_6.02206,224,024 - 206,224,170NCBIRnor6.0
Rnor_5.02225,647,734 - 225,647,880UniSTSRnor5.0
RGSC_v3.42198,963,085 - 198,963,231UniSTSRGSC3.4
Celera2183,720,662 - 183,720,808UniSTS
Cytogenetic Map2q34UniSTS
RH143441  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22191,249,105 - 191,249,355 (+)MAPPERmRatBN7.2
Rnor_6.02206,224,304 - 206,224,553NCBIRnor6.0
Rnor_5.02225,648,014 - 225,648,263UniSTSRnor5.0
RGSC_v3.42198,963,365 - 198,963,614UniSTSRGSC3.4
Celera2183,720,942 - 183,721,191UniSTS
RH 3.4 Map21326.6UniSTS
Cytogenetic Map2q34UniSTS
RH144541  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22191,299,282 - 191,299,460 (+)MAPPERmRatBN7.2
Rnor_6.02206,274,460 - 206,274,637NCBIRnor6.0
Rnor_5.02225,698,170 - 225,698,347UniSTSRnor5.0
RGSC_v3.42199,015,091 - 199,015,268UniSTSRGSC3.4
Celera2183,771,042 - 183,771,219UniSTS
RH 3.4 Map21327.9UniSTS
Cytogenetic Map2q34UniSTS
RH136831  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22191,249,515 - 191,249,660 (+)MAPPERmRatBN7.2
Rnor_6.02206,224,714 - 206,224,858NCBIRnor6.0
Rnor_5.02225,648,424 - 225,648,568UniSTSRnor5.0
RGSC_v3.42198,963,775 - 198,963,919UniSTSRGSC3.4
Celera2183,721,352 - 183,721,496UniSTS
RH 3.4 Map21326.7UniSTS
Cytogenetic Map2q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001100986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017590998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039102795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005500331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010063633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF460311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF460312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000056079   ⟹   ENSRNOP00000061079
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2191,248,817 - 191,298,902 (-)Ensembl
Rnor_6.0 Ensembl2206,224,015 - 206,274,079 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096033   ⟹   ENSRNOP00000077809
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2191,248,817 - 191,298,902 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113978   ⟹   ENSRNOP00000083225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2191,248,826 - 191,298,902 (-)Ensembl
RefSeq Acc Id: NM_001100986   ⟹   NP_001094456
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,987,344 (-)NCBI
mRatBN7.22191,248,817 - 191,298,902 (-)NCBI
Rnor_6.02206,224,015 - 206,274,079 (-)NCBI
Rnor_5.02225,647,725 - 225,698,674 (-)NCBI
RGSC_v3.42198,963,076 - 199,014,710 (-)RGD
Celera2183,720,653 - 183,770,661 (-)RGD
Sequence:
RefSeq Acc Id: XM_008761420   ⟹   XP_008759642
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,987,292 (-)NCBI
mRatBN7.22191,248,817 - 191,298,896 (-)NCBI
Rnor_6.02206,224,015 - 206,274,283 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039102788   ⟹   XP_038958716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,987,292 (-)NCBI
mRatBN7.22191,248,817 - 191,298,850 (-)NCBI
RefSeq Acc Id: XM_039102789   ⟹   XP_038958717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,987,296 (-)NCBI
mRatBN7.22191,248,817 - 191,298,854 (-)NCBI
RefSeq Acc Id: XM_039102792   ⟹   XP_038958720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,988,247 (-)NCBI
mRatBN7.22191,248,817 - 191,286,719 (-)NCBI
RefSeq Acc Id: XM_039102793   ⟹   XP_038958721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,988,247 (-)NCBI
mRatBN7.22191,248,817 - 191,286,719 (-)NCBI
RefSeq Acc Id: XM_039102794   ⟹   XP_038958722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,988,247 (-)NCBI
mRatBN7.22191,248,817 - 191,286,719 (-)NCBI
RefSeq Acc Id: XM_039102795   ⟹   XP_038958723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,968,959 (-)NCBI
mRatBN7.22191,248,817 - 191,280,736 (-)NCBI
RefSeq Acc Id: XM_063282279   ⟹   XP_063138349
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,988,247 (-)NCBI
RefSeq Acc Id: XM_063282280   ⟹   XP_063138350
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,988,247 (-)NCBI
RefSeq Acc Id: XM_063282282   ⟹   XP_063138352
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,977,454 (-)NCBI
RefSeq Acc Id: XM_063282283   ⟹   XP_063138353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,987,901 (-)NCBI
RefSeq Acc Id: XM_063282284   ⟹   XP_063138354
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,988,247 (-)NCBI
RefSeq Acc Id: XM_063282285   ⟹   XP_063138355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,987,907 (-)NCBI
RefSeq Acc Id: XM_063282286   ⟹   XP_063138356
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,987,902 (-)NCBI
RefSeq Acc Id: XM_063282287   ⟹   XP_063138357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,988,247 (-)NCBI
RefSeq Acc Id: XM_063282288   ⟹   XP_063138358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,937,261 - 193,987,726 (-)NCBI
RefSeq Acc Id: XM_063282289   ⟹   XP_063138359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,942,724 - 193,987,292 (-)NCBI
RefSeq Acc Id: XR_005500331
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,951,160 - 193,988,247 (-)NCBI
mRatBN7.22191,262,716 - 191,286,719 (-)NCBI
RefSeq Acc Id: XR_010063633
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82193,951,160 - 193,988,247 (-)NCBI
RefSeq Acc Id: NP_001094456   ⟸   NM_001100986
- UniProtKB: A4L9P6 (UniProtKB/Swiss-Prot),   A4L9P5 (UniProtKB/Swiss-Prot),   F1M8I6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008759642   ⟸   XM_008761420
- Peptide Label: isoform X8
- UniProtKB: A4L9P6 (UniProtKB/Swiss-Prot),   A4L9P5 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000061079   ⟸   ENSRNOT00000056079
RefSeq Acc Id: XP_038958717   ⟸   XM_039102789
- Peptide Label: isoform X3
- UniProtKB: A4L9P6 (UniProtKB/Swiss-Prot),   A4L9P5 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038958716   ⟸   XM_039102788
- Peptide Label: isoform X3
- UniProtKB: A4L9P6 (UniProtKB/Swiss-Prot),   A4L9P5 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038958722   ⟸   XM_039102794
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038958720   ⟸   XM_039102792
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038958721   ⟸   XM_039102793
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038958723   ⟸   XM_039102795
- Peptide Label: isoform X13
Ensembl Acc Id: ENSRNOP00000077809   ⟸   ENSRNOT00000096033
Ensembl Acc Id: ENSRNOP00000083225   ⟸   ENSRNOT00000113978
RefSeq Acc Id: XP_063138357   ⟸   XM_063282287
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063138354   ⟸   XM_063282284
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063138350   ⟸   XM_063282280
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063138349   ⟸   XM_063282279
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063138355   ⟸   XM_063282285
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063138356   ⟸   XM_063282286
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063138353   ⟸   XM_063282283
- Peptide Label: isoform X4
- UniProtKB: F1M8I6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138358   ⟸   XM_063282288
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063138352   ⟸   XM_063282282
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063138359   ⟸   XM_063282289
- Peptide Label: isoform X12
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A4L9P5-F1-model_v2 AlphaFold A4L9P5 1-1211 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691629
Promoter ID:EPDNEW_R2154
Type:initiation region
Name:Hipk1_1
Description:homeodomain interacting protein kinase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02206,274,153 - 206,274,213EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304941 AgrOrtholog
BioCyc Gene G2FUF-51800 BioCyc
Ensembl Genes ENSRNOG00000019333 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000056079.5 UniProtKB/TrEMBL
  ENSRNOT00000096033.1 UniProtKB/TrEMBL
  ENSRNOT00000113978.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser_Thr_dual-spec_kinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:365895 UniProtKB/TrEMBL
NCBI Gene 365895 ENTREZGENE
PANTHER DUAL SPECIFICITY PROTEIN KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HOMEODOMAIN-INTERACTING PROTEIN KINASE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hipk1 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019333 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5Y890_RAT UniProtKB/TrEMBL
  A0A8I5ZWS9_RAT UniProtKB/TrEMBL
  A4L9P5 ENTREZGENE
  A4L9P6 ENTREZGENE
  F1M8I6 ENTREZGENE, UniProtKB/TrEMBL
  HIPK1_RAT UniProtKB/Swiss-Prot
UniProt Secondary A4L9P6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Hipk1  homeodomain interacting protein kinase 1   Hipk1_predicted  homeodomain interacting protein kinase 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Hipk1_predicted  homeodomain interacting protein kinase 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED