Pdcd11 (programmed cell death 11) - Rat Genome Database

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Pathways
Gene: Pdcd11 (programmed cell death 11) Rattus norvegicus
Analyze
Symbol: Pdcd11
Name: programmed cell death 11
RGD ID: 1304933
Description: Predicted to enable NF-kappaB binding activity and RNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in cytosol and nucleus. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human PDCD11 (programmed cell death 11); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC309458; programmed cell death protein 11
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81255,922,198 - 255,963,336 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1255,922,225 - 255,963,336 (+)EnsemblGRCr8
mRatBN7.21245,980,840 - 246,021,999 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1245,980,880 - 246,021,999 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1254,107,190 - 254,148,728 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01260,800,488 - 260,842,289 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01253,449,999 - 253,490,785 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01266,866,931 - 266,908,042 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1266,866,931 - 266,908,042 (+)Ensemblrn6Rnor6.0
Rnor_5.01274,297,342 - 274,338,453 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41252,413,500 - 252,454,620 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1241,752,536 - 241,793,608 (+)NCBICelera
RGSC_v3.11252,679,744 - 252,718,472 (+)NCBI
Cytogenetic Map1q54NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
acetohydrazide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
atrazine  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
cannabidiol  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
clozapine  (ISO)
cocaine  (EXP)
coumarin  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
flutamide  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glafenine  (EXP)
ivermectin  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
motexafin gadolinium  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nitrates  (ISO)
okadaic acid  (ISO)
oxybenzone  (EXP)
ozone  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
triphenyl phosphate  (ISO)
triticonazole  (EXP)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc acetate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA,ISO)
nucleolus  (IBA,IEA,ISO)
nucleus  (IEA,ISO)
small-subunit processome  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing. Sloan KE, etal., J Cell Biol. 2013 Mar 4;200(5):577-88. doi: 10.1083/jcb.201207131. Epub 2013 Feb 25.
Additional References at PubMed
PMID:10229231   PMID:14624448   PMID:22658674   PMID:22681889  


Genomics

Comparative Map Data
Pdcd11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81255,922,198 - 255,963,336 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1255,922,225 - 255,963,336 (+)EnsemblGRCr8
mRatBN7.21245,980,840 - 246,021,999 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1245,980,880 - 246,021,999 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1254,107,190 - 254,148,728 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01260,800,488 - 260,842,289 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01253,449,999 - 253,490,785 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01266,866,931 - 266,908,042 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1266,866,931 - 266,908,042 (+)Ensemblrn6Rnor6.0
Rnor_5.01274,297,342 - 274,338,453 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41252,413,500 - 252,454,620 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1241,752,536 - 241,793,608 (+)NCBICelera
RGSC_v3.11252,679,744 - 252,718,472 (+)NCBI
Cytogenetic Map1q54NCBI
PDCD11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810103,396,626 - 103,446,294 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10103,396,626 - 103,446,297 (+)Ensemblhg38GRCh38
GRCh3710105,156,383 - 105,206,051 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610105,146,402 - 105,196,009 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3410105,146,448 - 105,195,463NCBI
Celera1098,896,345 - 98,945,951 (+)NCBICelera
Cytogenetic Map10q24.33NCBI
HuRef1098,787,205 - 98,836,814 (+)NCBIHuRef
CHM1_110105,440,531 - 105,490,136 (+)NCBICHM1_1
T2T-CHM13v2.010104,283,926 - 104,333,600 (+)NCBIT2T-CHM13v2.0
Pdcd11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391947,079,183 - 47,119,585 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1947,079,207 - 47,120,304 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381947,090,735 - 47,131,146 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1947,090,768 - 47,131,865 (+)Ensemblmm10GRCm38
MGSCv371947,165,256 - 47,205,636 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361947,144,077 - 47,184,457 (+)NCBIMGSCv36mm8
Celera1947,859,811 - 47,900,415 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1939.24NCBI
Pdcd11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554857,112,457 - 7,150,731 (-)Ensembl
ChiLan1.0NW_0049554857,110,704 - 7,152,301 (-)NCBIChiLan1.0ChiLan1.0
PDCD11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28115,281,089 - 115,330,352 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110115,286,418 - 115,335,681 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01099,994,509 - 100,043,784 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110103,455,649 - 103,504,784 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10103,455,649 - 103,504,784 (+)EnsemblpanPan2panpan1.1
PDCD11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12815,767,936 - 15,812,285 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2815,769,845 - 15,812,279 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2815,939,911 - 15,984,168 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02816,244,175 - 16,288,442 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2816,244,252 - 16,288,440 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12815,793,243 - 15,837,440 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02815,820,958 - 15,865,275 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02815,959,630 - 16,003,888 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pdcd11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721331,027,757 - 31,073,135 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366002,631,940 - 2,673,379 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366002,631,520 - 2,676,315 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDCD11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14114,327,625 - 114,379,179 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.114114,327,583 - 114,382,002 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PDCD11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1996,442,214 - 96,493,320 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl996,442,237 - 96,493,318 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604857,557,983 - 57,609,570 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pdcd11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248312,634,095 - 2,673,652 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248312,633,132 - 2,673,750 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pdcd11
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1246,624,930 - 46,662,771 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pdcd11
257 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:289
Count of miRNA genes:187
Interacting mature miRNAs:212
Transcripts:ENSRNOT00000027512
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1186658830266453731Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1210980612255980612Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1226175591270518180Rat
1578775Iddm21Insulin dependent diabetes mellitus QTL 214.13blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1245782829270518180Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1205233991267096252Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1218829748263829748Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1186658830266453731Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
631837Niddm35Non-insulin dependent diabetes mellitus QTL 350.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1248619887269633915Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1176288899270518180Rat
631836Stl31Serum triglyceride level QTL 314.645e-06blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1247133834270518180Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1205233991267096252Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1210980612255980612Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1237995023269633915Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1233480549270108840Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1200449456256003563Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1234540191270518180Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1233480549270108840Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1207163993269633915Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1210980612255980612Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1223134011262090599Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1210980612255980612Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1225108840270108840Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1228180370266453608Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1208479811269633915Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1224633915269633915Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1232312773270518180Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1212738576257738576Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1194786607262083703Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1210980612255980612Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1210980612255980612Rat
7387289Uae45Urinary albumin excretion QTL 452.860.0021urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1233204160270518180Rat
1598839Rf56Renal function QTL 56renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1255849111270518180Rat
1581544Rf52Renal function QTL 520.05urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1241569529269633915Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1210980612255980612Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1243953669270518180Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1185857683270518180Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1226175591270518180Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233349180270518180Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1210980612255980612Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1228174566270518180Rat

Markers in Region
BE107251  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21246,021,754 - 246,021,906 (+)MAPPERmRatBN7.2
Rnor_6.01266,907,798 - 266,907,949NCBIRnor6.0
Rnor_5.01274,338,209 - 274,338,360UniSTSRnor5.0
RGSC_v3.41252,454,376 - 252,454,527UniSTSRGSC3.4
Celera1241,793,364 - 241,793,515UniSTS
RH 3.4 Map11624.4UniSTS
Cytogenetic Map1q54UniSTS
AU048745  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q32UniSTS
Cytogenetic Map13q24UniSTS
Cytogenetic Map6q32UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map16p14UniSTS
Cytogenetic Map13q26UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map8q24UniSTS
Cytogenetic Map5q21UniSTS
Cytogenetic Map4q24UniSTS
Cytogenetic Map2q11UniSTS
Cytogenetic Map1q54UniSTS
Cytogenetic Map1q36UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map13q13UniSTS
Cytogenetic Map10q24UniSTS
Cytogenetic Map8q31UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map13p13UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map11q23UniSTS
Cytogenetic Map10q31UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map3q24UniSTS
Cytogenetic Map5q36UniSTS
Cytogenetic Map3p13UniSTS
RH129912  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21246,020,919 - 246,021,139 (+)MAPPERmRatBN7.2
Rnor_6.01266,906,963 - 266,907,182NCBIRnor6.0
Rnor_5.01274,337,374 - 274,337,593UniSTSRnor5.0
RGSC_v3.41252,453,541 - 252,453,760UniSTSRGSC3.4
Celera1241,792,529 - 241,792,748UniSTS
RH 3.4 Map11643.8UniSTS
Cytogenetic Map1q54UniSTS
BE119115  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21245,993,603 - 245,993,788 (+)MAPPERmRatBN7.2
Rnor_6.01266,879,655 - 266,879,839NCBIRnor6.0
Rnor_5.01274,310,066 - 274,310,250UniSTSRnor5.0
RGSC_v3.41252,426,224 - 252,426,408UniSTSRGSC3.4
Celera1241,765,260 - 241,765,444UniSTS
RH 3.4 Map11640.9UniSTS
Cytogenetic Map1q54UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000027512   ⟹   ENSRNOP00000027512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1255,922,225 - 255,963,336 (+)Ensembl
mRatBN7.2 Ensembl1245,980,880 - 246,021,999 (+)Ensembl
Rnor_6.0 Ensembl1266,866,931 - 266,908,042 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096398   ⟹   ENSRNOP00000092472
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1245,980,900 - 246,021,161 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097870   ⟹   ENSRNOP00000089018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1255,922,225 - 255,963,336 (+)Ensembl
mRatBN7.2 Ensembl1245,980,880 - 246,021,999 (+)Ensembl
RefSeq Acc Id: NM_001107604   ⟹   NP_001101074
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81255,922,225 - 255,963,336 (+)NCBI
mRatBN7.21245,980,880 - 246,021,999 (+)NCBI
Rnor_6.01266,866,931 - 266,908,042 (+)NCBI
Rnor_5.01274,297,342 - 274,338,453 (+)NCBI
RGSC_v3.41252,413,500 - 252,454,620 (+)RGD
Celera1241,752,536 - 241,793,608 (+)RGD
Sequence:
RefSeq Acc Id: XM_063265069   ⟹   XP_063121139
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81255,939,379 - 255,962,618 (+)NCBI
RefSeq Acc Id: XR_005487588
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81255,922,198 - 255,951,460 (+)NCBI
mRatBN7.21245,980,840 - 246,016,445 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001101074 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121139 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL94371 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027512
  ENSRNOP00000027512.4
  ENSRNOP00000089018.2
RefSeq Acc Id: NP_001101074   ⟸   NM_001107604
- UniProtKB: D3ZNI3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027512   ⟸   ENSRNOT00000027512
Ensembl Acc Id: ENSRNOP00000089018   ⟸   ENSRNOT00000097870
Ensembl Acc Id: ENSRNOP00000092472   ⟸   ENSRNOT00000096398
RefSeq Acc Id: XP_063121139   ⟸   XM_063265069
- Peptide Label: isoform X1
Protein Domains
S1 motif

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZNI3-F1-model_v2 AlphaFold D3ZNI3 1-1876 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690977
Promoter ID:EPDNEW_R1501
Type:initiation region
Name:Pdcd11_1
Description:programmed cell death 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01266,866,931 - 266,866,991EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304933 AgrOrtholog
BioCyc Gene G2FUF-55490 BioCyc
Ensembl Genes ENSRNOG00000020304 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000027512 ENTREZGENE
  ENSRNOT00000027512.5 UniProtKB/TrEMBL
  ENSRNOT00000097870.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  2.40.50.140 UniProtKB/TrEMBL
InterPro HAT UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  Rbsml_prot_S1_RNA-bd_dom UniProtKB/TrEMBL
  Rrp5 UniProtKB/TrEMBL
  Rrp5_S1 UniProtKB/TrEMBL
  Rrp5_S1_rpt_hs11_sc8 UniProtKB/TrEMBL
  Rrp5_S1_rpt_hs1_sc1 UniProtKB/TrEMBL
  Suf UniProtKB/TrEMBL
  TPR-like_helical UniProtKB/TrEMBL
NCBI Gene 309458 ENTREZGENE
PANTHER PROTEIN RRP5 HOMOLOG UniProtKB/TrEMBL
  PTHR23270 UniProtKB/TrEMBL
Pfam PF00575 UniProtKB/TrEMBL
  S1_RRP5 UniProtKB/TrEMBL
  Suf UniProtKB/TrEMBL
PhenoGen Pdcd11 PhenoGen
PROSITE PS50126 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020304 RatGTEx
SMART HAT UniProtKB/TrEMBL
  SM00316 UniProtKB/TrEMBL
Superfamily-SCOP Nucleic_acid_OB UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
UniProt A0A8I6AB17_RAT UniProtKB/TrEMBL
  D3ZNI3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-06-27 Pdcd11  programmed cell death 11  Pdcd11  programmed cell death protein 11   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pdcd11  programmed cell death protein 11   Pdcd11_predicted  programmed cell death protein 11 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pdcd11_predicted  programmed cell death protein 11 (predicted)      Symbol and Name status set to approved 70820 APPROVED