Cdk10 (cyclin-dependent kinase 10) - Rat Genome Database

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Gene: Cdk10 (cyclin-dependent kinase 10) Rattus norvegicus
Analyze
Symbol: Cdk10
Name: cyclin-dependent kinase 10
RGD ID: 1304851
Description: Predicted to enable cyclin-dependent protein kinase activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including negative regulation of cilium assembly; peptidyl-threonine phosphorylation; and regulation of cell cycle G2/M phase transition. Predicted to act upstream of or within positive regulation of MAPK cascade. Predicted to be located in ciliary basal body. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in nucleus. Orthologous to human CDK10 (cyclin dependent kinase 10); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: cell division protein kinase 10; cyclin-dependent kinase (CDC2-like) 10; LOC361434; MGC112847
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,168,040 - 68,184,923 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1968,169,874 - 68,177,599 (+)EnsemblGRCr8
mRatBN7.21951,260,012 - 51,273,009 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,261,356 - 51,269,078 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1958,056,299 - 58,064,014 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,736,292 - 58,744,004 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,954,899 - 60,962,616 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01956,024,903 - 56,032,610 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,024,903 - 56,032,605 (+)Ensemblrn6Rnor6.0
Rnor_5.01966,728,927 - 66,738,144 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41953,545,204 - 53,552,911 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1950,497,238 - 50,504,945 (+)NCBICelera
RGSC_v3.11953,551,287 - 53,557,788 (+)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:11006117   PMID:12477932   PMID:15489334   PMID:16751776   PMID:24218572   PMID:27104747  


Genomics

Comparative Map Data
Cdk10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81968,168,040 - 68,184,923 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1968,169,874 - 68,177,599 (+)EnsemblGRCr8
mRatBN7.21951,260,012 - 51,273,009 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1951,261,356 - 51,269,078 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1958,056,299 - 58,064,014 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,736,292 - 58,744,004 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,954,899 - 60,962,616 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01956,024,903 - 56,032,610 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,024,903 - 56,032,605 (+)Ensemblrn6Rnor6.0
Rnor_5.01966,728,927 - 66,738,144 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41953,545,204 - 53,552,911 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1950,497,238 - 50,504,945 (+)NCBICelera
RGSC_v3.11953,551,287 - 53,557,788 (+)NCBI
Cytogenetic Map19q12NCBI
CDK10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381689,686,689 - 89,696,354 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1689,680,737 - 89,696,369 (+)Ensemblhg38GRCh38
GRCh371689,753,097 - 89,762,762 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361688,280,577 - 88,290,263 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341688,280,578 - 88,290,262NCBI
Celera1674,817,511 - 74,827,207 (+)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1675,448,350 - 75,458,046 (+)NCBIHuRef
CHM1_11691,164,300 - 91,173,997 (+)NCBICHM1_1
T2T-CHM13v2.01695,771,455 - 95,781,117 (+)NCBIT2T-CHM13v2.0
Cdk10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,951,580 - 123,958,995 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,951,581 - 123,958,989 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm388123,224,841 - 123,232,256 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8123,224,842 - 123,232,250 (+)Ensemblmm10GRCm38
MGSCv378125,748,741 - 125,756,156 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368126,110,931 - 126,118,344 (+)NCBIMGSCv36mm8
Celera8127,463,881 - 127,471,305 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map872.09NCBI
Cdk10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555413,235,448 - 3,242,377 (+)Ensembl
ChiLan1.0NW_0049555413,235,441 - 3,242,377 (+)NCBIChiLan1.0ChiLan1.0
CDK10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21899,533,478 - 99,544,036 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116105,423,055 - 105,433,509 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01670,445,200 - 70,455,476 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11690,109,448 - 90,120,119 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1690,109,492 - 90,119,532 (+)EnsemblpanPan2panpan1.1
CDK10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1563,878,517 - 63,897,540 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl563,879,024 - 63,897,373 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha563,891,370 - 63,910,420 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0564,106,299 - 64,125,413 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,106,305 - 64,125,222 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,126,411 - 64,145,475 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0563,964,013 - 63,983,067 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0564,370,590 - 64,389,641 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cdk10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934924,598,384 - 24,606,038 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641347,882 - 359,660 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936641351,905 - 359,553 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6332,242 - 339,142 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16332,239 - 339,130 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26458,803 - 465,827 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDK10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1575,002,284 - 75,034,555 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl575,024,205 - 75,033,428 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666047460,826 - 472,086 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746281,092 - 291,026 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624746285,006 - 291,019 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cdk10
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11742,830,361 - 42,839,613 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:528
Count of miRNA genes:178
Interacting mature miRNAs:196
Transcripts:ENSRNOT00000021607, ENSRNOT00000066552
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)196124916174246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat

Markers in Region
RH132209  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21951,260,621 - 51,260,819 (+)MAPPERmRatBN7.2
Rnor_6.01956,024,152 - 56,024,349NCBIRnor6.0
Rnor_5.01966,729,025 - 66,729,222UniSTSRnor5.0
RGSC_v3.41953,544,453 - 53,544,650UniSTSRGSC3.4
Celera1950,496,487 - 50,496,684UniSTS
RH 3.4 Map19710.21UniSTS
Cytogenetic Map19q12UniSTS
RH141043  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21951,268,827 - 51,269,043 (+)MAPPERmRatBN7.2
Rnor_6.01956,032,357 - 56,032,572NCBIRnor6.0
Rnor_5.01966,737,230 - 66,737,445UniSTSRnor5.0
RGSC_v3.41953,552,658 - 53,552,873UniSTSRGSC3.4
Celera1950,504,692 - 50,504,907UniSTS
RH 3.4 Map19712.01UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001025722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001109936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001109937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063278162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC119635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI071224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN932869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN935585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ607073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY320517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000021607   ⟹   ENSRNOP00000021607
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1968,169,874 - 68,177,597 (+)Ensembl
mRatBN7.2 Ensembl1951,261,356 - 51,269,077 (+)Ensembl
Rnor_6.0 Ensembl1956,024,903 - 56,032,605 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000066552   ⟹   ENSRNOP00000059465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1968,171,097 - 68,177,599 (+)Ensembl
mRatBN7.2 Ensembl1951,262,576 - 51,269,078 (+)Ensembl
Rnor_6.0 Ensembl1956,026,106 - 56,032,605 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099003   ⟹   ENSRNOP00000077813
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1968,171,097 - 68,177,599 (+)Ensembl
mRatBN7.2 Ensembl1951,262,576 - 51,269,078 (+)Ensembl
RefSeq Acc Id: NM_001025722   ⟹   NP_001020893
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,171,097 - 68,177,602 (+)NCBI
mRatBN7.21951,262,576 - 51,269,081 (+)NCBI
Rnor_6.01956,026,106 - 56,032,610 (+)NCBI
Rnor_5.01966,728,927 - 66,738,144 (+)NCBI
RGSC_v3.41953,545,204 - 53,552,911 (+)RGD
Celera1950,498,441 - 50,504,945 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001109936   ⟹   NP_001103406
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,169,894 - 68,177,602 (+)NCBI
mRatBN7.21951,261,373 - 51,269,081 (+)NCBI
Rnor_6.01956,024,903 - 56,032,610 (+)NCBI
Rnor_5.01966,728,927 - 66,738,144 (+)NCBI
RGSC_v3.41953,545,204 - 53,552,911 (+)RGD
Celera1950,497,238 - 50,504,945 (+)RGD
Sequence:
RefSeq Acc Id: NM_001109937   ⟹   NP_001103407
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,169,895 - 68,177,602 (+)NCBI
mRatBN7.21951,261,374 - 51,269,081 (+)NCBI
Rnor_6.01956,024,904 - 56,032,610 (+)NCBI
Rnor_5.01966,728,927 - 66,738,144 (+)NCBI
RGSC_v3.41953,545,204 - 53,552,911 (+)RGD
Celera1950,497,239 - 50,504,945 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097881   ⟹   XP_038953809
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,169,904 - 68,177,598 (+)NCBI
mRatBN7.21951,262,764 - 51,269,077 (+)NCBI
RefSeq Acc Id: XM_039097882   ⟹   XP_038953810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,168,434 - 68,177,598 (+)NCBI
mRatBN7.21951,260,488 - 51,269,079 (+)NCBI
RefSeq Acc Id: XM_039097883   ⟹   XP_038953811
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,171,526 - 68,184,923 (+)NCBI
mRatBN7.21951,261,252 - 51,273,009 (+)NCBI
RefSeq Acc Id: XM_039097885   ⟹   XP_038953813
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,168,434 - 68,177,598 (+)NCBI
mRatBN7.21951,261,413 - 51,269,077 (+)NCBI
RefSeq Acc Id: XM_039097886   ⟹   XP_038953814
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,171,715 - 68,177,598 (+)NCBI
mRatBN7.21951,261,392 - 51,269,077 (+)NCBI
RefSeq Acc Id: XM_063278157   ⟹   XP_063134227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,171,526 - 68,184,923 (+)NCBI
RefSeq Acc Id: XM_063278158   ⟹   XP_063134228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,168,060 - 68,177,598 (+)NCBI
RefSeq Acc Id: XM_063278159   ⟹   XP_063134229
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,169,904 - 68,177,598 (+)NCBI
RefSeq Acc Id: XM_063278160   ⟹   XP_063134230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,168,069 - 68,177,598 (+)NCBI
RefSeq Acc Id: XM_063278161   ⟹   XP_063134231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,168,040 - 68,176,066 (+)NCBI
RefSeq Acc Id: XM_063278162   ⟹   XP_063134232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81968,174,660 - 68,177,598 (+)NCBI
RefSeq Acc Id: NP_001020893   ⟸   NM_001025722
- Peptide Label: isoform 3
- UniProtKB: Q4KM47 (UniProtKB/Swiss-Prot),   F1LSV8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103406   ⟸   NM_001109936
- Peptide Label: isoform 1
- UniProtKB: G3V814 (UniProtKB/TrEMBL),   A6IZW8 (UniProtKB/TrEMBL),   A6IZW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103407   ⟸   NM_001109937
- Peptide Label: isoform 2
- UniProtKB: Q4KM47 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021607   ⟸   ENSRNOT00000021607
Ensembl Acc Id: ENSRNOP00000059465   ⟸   ENSRNOT00000066552
RefSeq Acc Id: XP_038953810   ⟸   XM_039097882
- Peptide Label: isoform X2
- UniProtKB: A6IZW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953811   ⟸   XM_039097883
- Peptide Label: isoform X3
- UniProtKB: Q4KM47 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038953814   ⟸   XM_039097886
- Peptide Label: isoform X5
- UniProtKB: Q4KM47 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038953813   ⟸   XM_039097885
- Peptide Label: isoform X5
- UniProtKB: Q4KM47 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038953809   ⟸   XM_039097881
- Peptide Label: isoform X1
- UniProtKB: Q4KM47 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000077813   ⟸   ENSRNOT00000099003
RefSeq Acc Id: XP_063134231   ⟸   XM_063278161
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063134228   ⟸   XM_063278158
- Peptide Label: isoform X5
- UniProtKB: Q4KM47 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063134230   ⟸   XM_063278160
- Peptide Label: isoform X6
- UniProtKB: Q4KM47 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063134229   ⟸   XM_063278159
- Peptide Label: isoform X5
- UniProtKB: Q4KM47 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063134227   ⟸   XM_063278157
- Peptide Label: isoform X4
- UniProtKB: Q4KM47 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063134232   ⟸   XM_063278162
- Peptide Label: isoform X8
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KM47-F1-model_v2 AlphaFold Q4KM47 1-358 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701221
Promoter ID:EPDNEW_R11745
Type:multiple initiation site
Name:Cdk10_1
Description:cyclin-dependent kinase 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01956,024,896 - 56,024,956EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304851 AgrOrtholog
BioCyc Gene G2FUF-5335 BioCyc
Ensembl Genes ENSRNOG00000016088 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000021607 ENTREZGENE
  ENSRNOT00000066552 ENTREZGENE
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/Swiss-Prot
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7376321 IMAGE-MGC_LOAD
InterPro CDK UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot
  Prot_kinase_dom UniProtKB/Swiss-Prot
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot
  STKc_CDK10 UniProtKB/Swiss-Prot
KEGG Report rno:361434 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112847 IMAGE-MGC_LOAD
NCBI Gene 361434 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/Swiss-Prot
  CYCLIN-DEPENDENT KINASE 10 UniProtKB/Swiss-Prot
Pfam Pkinase UniProtKB/Swiss-Prot
PhenoGen Cdk10 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016088 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot
UniProt A0A8I5Y1M3_RAT UniProtKB/TrEMBL
  A6IZW7 ENTREZGENE, UniProtKB/TrEMBL
  A6IZW8 ENTREZGENE, UniProtKB/TrEMBL
  CDK10_RAT UniProtKB/Swiss-Prot
  F1LSV8 ENTREZGENE, UniProtKB/TrEMBL
  G3V814 ENTREZGENE, UniProtKB/TrEMBL
  Q4KM47 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-29 Cdk10  cyclin-dependent kinase 10  Cdk10  cyclin-dependent kinase (CDC2-like) 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Cdk10  cyclin-dependent kinase (CDC2-like) 10  Cdk10_predicted  cyclin-dependent kinase (CDC2-like) 10 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Cdk10_predicted  cyclin-dependent kinase (CDC2-like) 10 (predicted)      Symbol and Name status set to approved 70820 APPROVED