Mettl14 (methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit) - Rat Genome Database

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Gene: Mettl14 (methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit) Rattus norvegicus
Analyze
Symbol: Mettl14
Name: methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit
RGD ID: 1304822
Description: Predicted to enable mRNA binding activity and mRNA m(6)A methyltransferase activity. Involved in response to nutrient levels. Predicted to be located in nucleoplasm. Predicted to be part of RNA N6-methyladenosine methyltransferase complex. Predicted to be active in nucleus. Biomarker of traumatic brain injury. Orthologous to human METTL14 (methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit); INTERACTS WITH all-trans-retinoic acid; azoxystrobin; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC295428; methyltransferase 14, N6-adenosine-methyltransferase subunit; methyltransferase like 14; methyltransferase-like protein 14; N6-adenosine-methyltransferase non-catalytic subunit; N6-adenosine-methyltransferase subunit METTL14; RGD1304822; similar to KIAA1627 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82214,215,165 - 214,231,412 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2214,215,165 - 214,231,412 (-)EnsemblGRCr8
mRatBN7.22211,530,598 - 211,546,845 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2211,530,602 - 211,546,821 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2219,202,456 - 219,218,700 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02217,102,330 - 217,118,574 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02211,956,574 - 211,972,818 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02227,566,811 - 227,583,047 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2227,566,815 - 227,582,895 (-)Ensemblrn6Rnor6.0
Rnor_5.02246,923,967 - 246,940,192 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42220,100,824 - 220,116,567 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2203,944,258 - 203,960,057 (-)NCBICelera
RGSC_v3.12220,063,883 - 220,079,920 (-)NCBI
Cytogenetic Map2q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Nutrition modulates Fto and Irx3 gene transcript levels, but does not alter their DNA methylation profiles in rat white adipose tissues. Nowacka-Woszuk J, etal., Gene. 2017 Apr 30;610:44-48. doi: 10.1016/j.gene.2017.02.002. Epub 2017 Feb 5.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Epitranscriptomic profiling of N6-methyladenosine-related RNA methylation in rat cerebral cortex following traumatic brain injury. Yu J, etal., Mol Brain. 2020 Jan 28;13(1):11. doi: 10.1186/s13041-020-0554-0.
Additional References at PubMed
PMID:12477932   PMID:24316715   PMID:24394384   PMID:24981863   PMID:25719671   PMID:26458103   PMID:27281194   PMID:27373337   PMID:27627798   PMID:28914256   PMID:28965759   PMID:29348140  
PMID:29507755   PMID:29547716   PMID:31697949   PMID:33197240   PMID:34018360   PMID:35013106   PMID:36878846   PMID:37094938   PMID:37541353   PMID:39175261  


Genomics

Comparative Map Data
Mettl14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82214,215,165 - 214,231,412 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2214,215,165 - 214,231,412 (-)EnsemblGRCr8
mRatBN7.22211,530,598 - 211,546,845 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2211,530,602 - 211,546,821 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2219,202,456 - 219,218,700 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02217,102,330 - 217,118,574 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02211,956,574 - 211,972,818 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02227,566,811 - 227,583,047 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2227,566,815 - 227,582,895 (-)Ensemblrn6Rnor6.0
Rnor_5.02246,923,967 - 246,940,192 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42220,100,824 - 220,116,567 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2203,944,258 - 203,960,057 (-)NCBICelera
RGSC_v3.12220,063,883 - 220,079,920 (-)NCBI
Cytogenetic Map2q42NCBI
METTL14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384118,685,392 - 118,715,430 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4118,685,387 - 118,715,433 (+)Ensemblhg38GRCh38
GRCh374119,606,547 - 119,636,585 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364119,826,022 - 119,851,538 (+)NCBIBuild 36Build 36hg18NCBI36
Celera4116,967,249 - 116,992,643 (+)NCBICelera
Cytogenetic Map4q26NCBI
HuRef4115,328,317 - 115,353,645 (+)NCBIHuRef
CHM1_14119,582,519 - 119,608,035 (+)NCBICHM1_1
T2T-CHM13v2.04121,990,699 - 122,020,747 (+)NCBIT2T-CHM13v2.0
Mettl14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393123,161,944 - 123,179,639 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3123,161,946 - 123,179,757 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm383123,368,295 - 123,385,990 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3123,368,297 - 123,386,108 (-)Ensemblmm10GRCm38
MGSCv373123,071,213 - 123,088,908 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv363123,360,319 - 123,377,970 (-)NCBIMGSCv36mm8
Celera3129,790,343 - 129,808,044 (-)NCBICelera
Cytogenetic Map3G1NCBI
cM Map353.96NCBI
Mettl14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542821,475,981 - 21,507,730 (-)Ensembl
ChiLan1.0NW_00495542821,475,981 - 21,507,730 (-)NCBIChiLan1.0ChiLan1.0
METTL14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23116,467,831 - 116,493,884 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14116,764,585 - 116,791,448 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04110,879,137 - 110,905,131 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14121,431,026 - 121,458,392 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4121,431,026 - 121,458,392 (+)EnsemblpanPan2panpan1.1
METTL14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13237,653,163 - 37,679,577 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3237,653,035 - 37,678,398 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha324,395,329 - 4,421,830 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03237,874,325 - 37,900,828 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3237,874,340 - 37,900,812 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13237,896,775 - 37,923,279 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03237,620,069 - 37,646,570 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0322,154,427 - 2,180,939 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mettl14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530167,698,472 - 67,771,356 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936869568,840 - 590,269 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936869568,324 - 589,972 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
METTL14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8105,015,420 - 105,053,563 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.18105,019,539 - 105,053,603 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28112,710,190 - 112,744,393 (-)NCBISscrofa10.2Sscrofa10.2susScr3
METTL14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1766,169,080 - 66,195,324 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl766,168,855 - 66,194,121 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603745,007,010 - 45,033,195 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mettl14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248675,508,886 - 5,533,395 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248675,508,847 - 5,533,395 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Mettl14
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1336,423,754 - 36,446,619 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mettl14
131 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:283
Count of miRNA genes:108
Interacting mature miRNAs:130
Transcripts:ENSRNOT00000020574, ENSRNOT00000065222
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2163997722225110681Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2169358774214358774Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170656145239614549Rat
631563Hcuc3Hepatic copper content QTL 33.87liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)2212145502231732847Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2149957381221199885Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2204795005249795005Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
1581578Cm49Cardiac mass QTL 494.90.01heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2145807215220931416Rat
61458Bp10Blood pressure QTL 103.42arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2191709311217961898Rat
1302789Stl26Serum triglyceride level QTL 263.10.0035blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)2206613059226891081Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2122597372215234002Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2196140964251540988Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170652929215652929Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2205135267250135267Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2159440891220931218Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2188565047233565047Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2192287802229609668Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2184856304229856304Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2184856304229856304Rat
631203Gluco14Glucose level QTL 140.0001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)2209350500221678003Rat
1298083Bp158Blood pressure QTL 1582.62arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2191709311217961898Rat
1357991Ael2Aortic elastin QTL 24.20.000071aorta elastin amount (VT:0003905)aortic elastin2169227906214227906Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
1331745Bp203Blood pressure QTL 2034.377arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2192287802221089121Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2184856304229856304Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2192287802237287802Rat
1578671Bmd10Bone mineral density QTL 105.4femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)2175931416220931416Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2182024327227024327Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2159440760228950743Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2184482291229482291Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2205135267250135267Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2202029709236904960Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2210956252251712708Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2205135267225627153Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2114384617215381366Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2186850607231850607Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2192287802237287802Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2114384617215381366Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660223841096Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2182635347227635347Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2175008837220008837Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2184856304229856304Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2203664411248664411Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166372086229820014Rat

Markers in Region
BI274279  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22211,530,900 - 211,531,075 (+)MAPPERmRatBN7.2
Rnor_6.02227,567,114 - 227,567,288NCBIRnor6.0
Rnor_5.02246,924,270 - 246,924,444UniSTSRnor5.0
RGSC_v3.42220,101,121 - 220,101,295UniSTSRGSC3.4
Celera2203,944,555 - 203,944,729UniSTS
RH 3.4 Map21545.6UniSTS
Cytogenetic Map2q42UniSTS
BE115462  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82214,221,748 - 214,221,899 (+)Marker Load Pipeline
mRatBN7.22211,537,181 - 211,537,332 (+)MAPPERmRatBN7.2
Rnor_6.02227,573,373 - 227,573,523NCBIRnor6.0
Rnor_5.02246,930,529 - 246,930,679UniSTSRnor5.0
RGSC_v3.42220,107,346 - 220,107,496UniSTSRGSC3.4
Celera2203,950,836 - 203,950,986UniSTS
RH 3.4 Map21546.2UniSTS
Cytogenetic Map2q42UniSTS
RH139373  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22211,530,774 - 211,530,923 (+)MAPPERmRatBN7.2
Rnor_6.02227,566,988 - 227,567,136NCBIRnor6.0
Rnor_5.02246,924,144 - 246,924,292UniSTSRnor5.0
RGSC_v3.42220,100,995 - 220,101,143UniSTSRGSC3.4
Celera2203,944,429 - 203,944,577UniSTS
RH 3.4 Map21545.7UniSTS
Cytogenetic Map2q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000020574   ⟹   ENSRNOP00000020574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2214,215,165 - 214,231,412 (-)Ensembl
mRatBN7.2 Ensembl2211,530,602 - 211,546,704 (-)Ensembl
Rnor_6.0 Ensembl2227,566,815 - 227,582,895 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000065222   ⟹   ENSRNOP00000061420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2214,215,291 - 214,231,412 (-)Ensembl
mRatBN7.2 Ensembl2211,530,604 - 211,546,403 (-)Ensembl
Rnor_6.0 Ensembl2227,566,817 - 227,582,594 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106170   ⟹   ENSRNOP00000086847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2214,218,098 - 214,231,412 (-)Ensembl
mRatBN7.2 Ensembl2211,533,531 - 211,546,821 (-)Ensembl
RefSeq Acc Id: NM_001399249   ⟹   NP_001386178
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82214,215,165 - 214,231,412 (-)NCBI
mRatBN7.22211,530,598 - 211,546,845 (-)NCBI
RefSeq Acc Id: XM_039102094   ⟹   XP_038958022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82214,215,165 - 214,226,606 (-)NCBI
mRatBN7.22211,530,598 - 211,542,041 (-)NCBI
Ensembl Acc Id: ENSRNOP00000061420   ⟸   ENSRNOT00000065222
Ensembl Acc Id: ENSRNOP00000020574   ⟸   ENSRNOT00000020574
RefSeq Acc Id: XP_038958022   ⟸   XM_039102094
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000086847   ⟸   ENSRNOT00000106170
RefSeq Acc Id: NP_001386178   ⟸   NM_001399249
- UniProtKB: B2RYI4 (UniProtKB/TrEMBL),   A6HVI9 (UniProtKB/TrEMBL),   F7F7M4 (UniProtKB/TrEMBL),   A6HVJ1 (UniProtKB/TrEMBL),   D4A701 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RYI4-F1-model_v2 AlphaFold B2RYI4 1-456 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304822 AgrOrtholog
BioCyc Gene G2FUF-51327 BioCyc
Ensembl Genes ENSRNOG00000015250 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020574 ENTREZGENE
  ENSRNOT00000020574.9 UniProtKB/TrEMBL
  ENSRNOT00000065222.3 UniProtKB/TrEMBL
  ENSRNOT00000106170.2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7936402 IMAGE-MGC_LOAD
InterPro METTL14-like UniProtKB/TrEMBL
  MT-A70 UniProtKB/TrEMBL
  SAM-dependent_MTases-like UniProtKB/TrEMBL
MGC_CLONE MGC:188575 IMAGE-MGC_LOAD
NCBI Gene 295428 ENTREZGENE
PANTHER N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT UniProtKB/TrEMBL
  PTHR13107 UniProtKB/TrEMBL
Pfam MT-A70 UniProtKB/TrEMBL
PhenoGen Mettl14 PhenoGen
PROSITE MT_A70 UniProtKB/TrEMBL
  SAM_MTA70L_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015250 RatGTEx
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A8I6A645_RAT UniProtKB/TrEMBL
  A6HVI9 ENTREZGENE, UniProtKB/TrEMBL
  A6HVJ1 ENTREZGENE, UniProtKB/TrEMBL
  B2RYI4 ENTREZGENE
  D4A701 ENTREZGENE, UniProtKB/TrEMBL
  F7F7M4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B2RYI4 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-03-25 Mettl14  methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit  Mettl14  methyltransferase 14, N6-adenosine-methyltransferase subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2022-06-17 Mettl14  methyltransferase 14, N6-adenosine-methyltransferase subunit  Mettl14  methyltransferase like 14  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-12 Mettl14  methyltransferase like 14  RGD1304822  similar to KIAA1627 protein   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1304822  similar to KIAA1627 protein   RGD1304822_predicted  similar to KIAA1627 protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1304822_predicted  similar to KIAA1627 protein (predicted)  LOC295428_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC295428_predicted  similar to KIAA1627 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL