Ano6 (anoctamin 6) - Rat Genome Database

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Gene: Ano6 (anoctamin 6) Rattus norvegicus
Analyze
Symbol: Ano6
Name: anoctamin 6
RGD ID: 1304765
Description: Predicted to enable monoatomic ion channel activity; phospholipid scramblase activity; and protein homodimerization activity. Involved in positive regulation of potassium ion export across plasma membrane. Predicted to be located in cytosol. Predicted to be part of chloride channel complex. Predicted to be active in cholinergic synapse and synaptic membrane. Human ortholog(s) of this gene implicated in Scott syndrome; ankylosing spondylitis; and inflammatory bowel disease. Orthologous to human ANO6 (anoctamin 6); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: anoctamin-6; LOC315272; Tmem16f; transmembrane protein 16F
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87128,812,842 - 128,992,805 (+)NCBIGRCr8
mRatBN7.27126,933,919 - 127,113,588 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7126,933,936 - 127,113,589 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7128,733,569 - 128,913,454 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07130,959,091 - 131,138,975 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07130,864,863 - 131,044,680 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07137,142,063 - 137,335,208 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7137,142,170 - 137,335,208 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07136,781,570 - 136,973,259 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47134,434,775 - 134,624,126 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17134,511,298 - 134,697,841 (+)NCBI
Celera7123,442,149 - 123,619,990 (+)NCBICelera
Cytogenetic Map7q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing. Huang F, etal., Nat Neurosci. 2013 Sep;16(9):1284-90. doi: 10.1038/nn.3468. Epub 2013 Jul 21.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Association study of polymorphisms rs4552569 and rs17095830 and the risk of ankylosing spondylitis in a Taiwanese population. Wei JC, etal., PLoS One. 2013;8(1):e52801. doi: 10.1371/journal.pone.0052801. Epub 2013 Jan 4.
Additional References at PubMed
PMID:12477932   PMID:19056867   PMID:19199708   PMID:19581412   PMID:19946888   PMID:20056604   PMID:20458337   PMID:21107324   PMID:21984732   PMID:22006324   PMID:22075693   PMID:22936354  
PMID:22946059   PMID:23021219   PMID:23159814   PMID:23376485   PMID:23532839   PMID:23533145   PMID:23576756   PMID:25589784   PMID:25651887   PMID:30785399   PMID:32733436  


Genomics

Comparative Map Data
Ano6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87128,812,842 - 128,992,805 (+)NCBIGRCr8
mRatBN7.27126,933,919 - 127,113,588 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7126,933,936 - 127,113,589 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7128,733,569 - 128,913,454 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07130,959,091 - 131,138,975 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07130,864,863 - 131,044,680 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07137,142,063 - 137,335,208 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7137,142,170 - 137,335,208 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07136,781,570 - 136,973,259 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47134,434,775 - 134,624,126 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17134,511,298 - 134,697,841 (+)NCBI
Celera7123,442,149 - 123,619,990 (+)NCBICelera
Cytogenetic Map7q35NCBI
ANO6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381245,216,095 - 45,440,404 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1245,215,987 - 45,482,280 (+)EnsemblGRCh38hg38GRCh38
GRCh371245,609,878 - 45,834,187 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361243,896,170 - 44,112,399 (+)NCBINCBI36Build 36hg18NCBI36
Celera1244,413,462 - 44,637,876 (+)NCBICelera
Cytogenetic Map12q12NCBI
HuRef1242,638,190 - 42,862,629 (+)NCBIHuRef
CHM1_11245,574,740 - 45,799,189 (+)NCBICHM1_1
T2T-CHM13v2.01245,174,737 - 45,399,096 (+)NCBIT2T-CHM13v2.0
Ano6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391595,688,724 - 95,873,353 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1595,688,724 - 95,872,632 (+)EnsemblGRCm39 Ensembl
GRCm381595,790,843 - 95,975,472 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1595,790,843 - 95,974,751 (+)EnsemblGRCm38mm10GRCm38
MGSCv371595,621,274 - 95,805,205 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361595,618,877 - 95,802,808 (+)NCBIMGSCv36mm8
Celera1597,939,179 - 98,118,870 (+)NCBICelera
Cytogenetic Map15E3- F1NCBI
cM Map1550.66NCBI
Ano6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555004,462,524 - 4,652,782 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555004,462,314 - 4,652,634 (+)NCBIChiLan1.0ChiLan1.0
ANO6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21048,733,953 - 48,950,131 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11248,730,709 - 48,947,193 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01243,295,928 - 43,512,073 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11244,164,375 - 44,380,261 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1244,164,375 - 44,303,259 (-)Ensemblpanpan1.1panPan2
ANO6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1278,882,691 - 9,067,057 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl278,884,062 - 9,066,934 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2737,246,426 - 37,430,774 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0279,072,368 - 9,257,318 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl279,074,398 - 9,257,197 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,878,877 - 9,063,444 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0278,918,866 - 9,103,666 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02737,484,107 - 37,668,815 (+)NCBIUU_Cfam_GSD_1.0
Ano6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494569,429,550 - 69,515,718 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365123,540,129 - 3,732,776 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365123,649,103 - 3,736,274 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANO6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl576,113,236 - 76,337,069 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1576,112,428 - 76,337,073 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2578,998,214 - 79,219,973 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ANO6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11141,420,206 - 41,633,323 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1141,419,901 - 41,633,347 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037204,821,696 - 205,033,977 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ano6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248166,894,413 - 7,077,883 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248166,896,176 - 7,077,758 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ano6
1775 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:606
Count of miRNA genes:284
Interacting mature miRNAs:357
Transcripts:ENSRNOT00000068742
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
631201Panci1Pancreas inflammation QTL 100.001pancreas integrity trait (VT:0010560)percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)7116677189127103496Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

Markers in Region
D7Rat4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27127,103,496 - 127,103,614 (+)MAPPERmRatBN7.2
Rnor_6.07137,325,116 - 137,325,233NCBIRnor6.0
Rnor_5.07136,963,167 - 136,963,284UniSTSRnor5.0
RGSC_v3.47134,614,034 - 134,614,151UniSTSRGSC3.4
RGSC_v3.47134,614,033 - 134,614,151RGDRGSC3.4
RGSC_v3.17134,690,471 - 134,690,588RGD
Celera7123,609,897 - 123,610,014UniSTS
RH 3.4 Map71092.0RGD
RH 3.4 Map71092.0UniSTS
RH 2.0 Map7773.9RGD
SHRSP x BN Map780.4799RGD
FHH x ACI Map766.88RGD
Cytogenetic Map7q35UniSTS
BE108488  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27126,993,358 - 126,993,510 (+)MAPPERmRatBN7.2
Rnor_6.07137,201,790 - 137,201,941NCBIRnor6.0
Rnor_5.07136,840,875 - 136,841,026UniSTSRnor5.0
Celera7123,500,742 - 123,500,893UniSTS
RH 3.4 Map71045.9UniSTS
Cytogenetic Map7q35UniSTS
RH130346  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27127,113,282 - 127,113,496 (+)MAPPERmRatBN7.2
Rnor_6.07137,334,902 - 137,335,115NCBIRnor6.0
Rnor_5.07136,972,953 - 136,973,166UniSTSRnor5.0
RGSC_v3.47134,623,820 - 134,624,033UniSTSRGSC3.4
Celera7123,619,684 - 123,619,897UniSTS
RH 3.4 Map71136.1UniSTS
Cytogenetic Map7q35UniSTS
BM387481  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27126,970,408 - 126,970,564 (+)MAPPERmRatBN7.2
Rnor_6.07137,178,850 - 137,179,005NCBIRnor6.0
Rnor_5.07136,818,362 - 136,818,517UniSTSRnor5.0
Celera7123,477,695 - 123,477,850UniSTS
RH 3.4 Map71122.9UniSTS
Cytogenetic Map7q35UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 33 35 19 19 19 6 9 56 35 41 11 6
Low 1 10 22 22 22 2 2 18 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000068742   ⟹   ENSRNOP00000059010
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7126,934,008 - 127,113,589 (+)Ensembl
Rnor_6.0 Ensembl7137,142,170 - 137,335,208 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000089895   ⟹   ENSRNOP00000071905
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7126,947,461 - 127,113,420 (+)Ensembl
Rnor_6.0 Ensembl7137,155,481 - 137,332,519 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098138   ⟹   ENSRNOP00000089627
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7126,934,008 - 127,113,589 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098487   ⟹   ENSRNOP00000081155
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7126,933,961 - 127,113,420 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000099376   ⟹   ENSRNOP00000082207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7126,976,706 - 127,113,589 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000100449   ⟹   ENSRNOP00000092185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7126,933,936 - 127,113,420 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110510   ⟹   ENSRNOP00000077951
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7126,976,778 - 127,113,420 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116780   ⟹   ENSRNOP00000080814
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7126,939,780 - 127,113,301 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000117459   ⟹   ENSRNOP00000094815
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7126,947,657 - 127,113,420 (+)Ensembl
RefSeq Acc Id: NM_001401001   ⟹   NP_001387930
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87128,813,131 - 128,992,805 (+)NCBI
mRatBN7.27126,933,919 - 127,113,588 (+)NCBI
RefSeq Acc Id: XM_008765735   ⟹   XP_008763957
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87128,812,842 - 128,992,805 (+)NCBI
mRatBN7.27126,934,095 - 127,113,588 (+)NCBI
Rnor_6.07137,142,063 - 137,335,207 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079318   ⟹   XP_038935246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87128,856,192 - 128,992,805 (+)NCBI
mRatBN7.27126,977,029 - 127,113,588 (+)NCBI
RefSeq Acc Id: XM_039079319   ⟹   XP_038935247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87128,856,181 - 128,992,805 (+)NCBI
mRatBN7.27126,977,014 - 127,113,588 (+)NCBI
RefSeq Acc Id: XM_039079320   ⟹   XP_038935248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87128,826,402 - 128,992,805 (+)NCBI
mRatBN7.27126,947,758 - 127,113,588 (+)NCBI
RefSeq Acc Id: XM_039079322   ⟹   XP_038935250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87128,826,408 - 128,992,805 (+)NCBI
mRatBN7.27126,947,756 - 127,113,588 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008763957   ⟸   XM_008765735
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AA94 (UniProtKB/TrEMBL),   A0A8I6G530 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071905   ⟸   ENSRNOT00000089895
RefSeq Acc Id: ENSRNOP00000059010   ⟸   ENSRNOT00000068742
RefSeq Acc Id: XP_038935250   ⟸   XM_039079322
- Peptide Label: isoform X5
- UniProtKB: A0A8I6ASC3 (UniProtKB/TrEMBL),   A0A8I6G530 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935248   ⟸   XM_039079320
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K1M7 (UniProtKB/TrEMBL),   A0A8I6G530 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935247   ⟸   XM_039079319
- Peptide Label: isoform X3
- UniProtKB: A0A8I6G530 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935246   ⟸   XM_039079318
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y1S2 (UniProtKB/TrEMBL),   A0A8I6G530 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000089627   ⟸   ENSRNOT00000098138
RefSeq Acc Id: ENSRNOP00000082207   ⟸   ENSRNOT00000099376
RefSeq Acc Id: ENSRNOP00000077951   ⟸   ENSRNOT00000110510
RefSeq Acc Id: ENSRNOP00000094815   ⟸   ENSRNOT00000117459
RefSeq Acc Id: ENSRNOP00000080814   ⟸   ENSRNOT00000116780
RefSeq Acc Id: ENSRNOP00000081155   ⟸   ENSRNOT00000098487
RefSeq Acc Id: ENSRNOP00000092185   ⟸   ENSRNOT00000100449
RefSeq Acc Id: NP_001387930   ⟸   NM_001401001
- UniProtKB: A0A8I5ZRU7 (UniProtKB/TrEMBL)
Protein Domains
Anoctamin dimerisation   Anoctamin transmembrane

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K1M7-F1-model_v2 AlphaFold A0A0G2K1M7 1-909 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695605
Promoter ID:EPDNEW_R6130
Type:multiple initiation site
Name:Ano6_1
Description:anoctamin 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R6131  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07137,142,084 - 137,142,144EPDNEW
RGD ID:13695607
Promoter ID:EPDNEW_R6131
Type:multiple initiation site
Name:Ano6_2
Description:anoctamin 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R6130  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07137,155,573 - 137,155,633EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304765 AgrOrtholog
BioCyc Gene G2FUF-32281 BioCyc
Ensembl Genes ENSRNOG00000006995 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000068742.4 UniProtKB/TrEMBL
  ENSRNOT00000089895.2 UniProtKB/TrEMBL
  ENSRNOT00000098138.1 UniProtKB/TrEMBL
  ENSRNOT00000098487 ENTREZGENE
  ENSRNOT00000098487.1 UniProtKB/TrEMBL
  ENSRNOT00000099376.1 UniProtKB/TrEMBL
  ENSRNOT00000100449.1 UniProtKB/TrEMBL
  ENSRNOT00000110510.1 UniProtKB/TrEMBL
  ENSRNOT00000116780.1 UniProtKB/TrEMBL
  ENSRNOT00000117459.1 UniProtKB/TrEMBL
InterPro Anoct_dimer UniProtKB/TrEMBL
  Anoctamin UniProtKB/TrEMBL
  Anoctamin_TM UniProtKB/TrEMBL
KEGG Report rno:315272 UniProtKB/TrEMBL
NCBI Gene 315272 ENTREZGENE
PANTHER DUF590 UniProtKB/TrEMBL
  PTHR12308:SF21 UniProtKB/TrEMBL
Pfam Anoct_dimer UniProtKB/TrEMBL
  Anoctamin UniProtKB/TrEMBL
PhenoGen Ano6 PhenoGen
RatGTEx ENSRNOG00000006995 RatGTEx
UniProt A0A0G2K1M7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y1S2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZRU7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZT68_RAT UniProtKB/TrEMBL
  A0A8I6AA94 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AHD2_RAT UniProtKB/TrEMBL
  A0A8I6ASC3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G530 ENTREZGENE, UniProtKB/TrEMBL
  F1M5Z5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-25 Ano6  anoctamin 6  Tmem16f  transmembrane protein 16F   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Tmem16f  transmembrane protein 16F   Tmem16f_predicted  transmembrane protein 16F (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Tmem16f_predicted  transmembrane protein 16F (predicted)      Symbol and Name status set to approved 70820 APPROVED