Asxl2 (ASXL transcriptional regulator 2) - Rat Genome Database

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Gene: Asxl2 (ASXL transcriptional regulator 2) Rattus norvegicus
Analyze
Symbol: Asxl2
Name: ASXL transcriptional regulator 2
RGD ID: 1304710
Description: Predicted to enable chromatin binding activity and peroxisome proliferator activated receptor binding activity. Involved in positive regulation of lipid storage. Predicted to be located in nucleoplasm. Predicted to be part of PR-DUB complex. Orthologous to human ASXL2 (ASXL transcriptional regulator 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; gentamycin; valproic acid.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: additional sex combs like 2; additional sex combs like 2 (Drosophila); additional sex combs like 2, transcriptional regulator; additional sex combs like transcriptional regulator 2; LOC313922; putative Polycomb group protein ASXL2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8632,090,497 - 32,234,487 (+)NCBIGRCr8
mRatBN7.2626,425,017 - 26,514,899 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl626,425,954 - 26,507,477 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0627,835,346 - 27,919,285 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl627,887,797 - 27,915,563 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0637,644,433 - 37,732,264 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4626,400,855 - 26,482,465 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1626,470,864 - 26,484,531 (+)NCBI
Celera625,902,447 - 25,987,120 (+)NCBICelera
Cytogenetic Map6q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Asxl2Ratautism spectrum disorder  ISOASXL2 (Homo sapiens)8554872ClinVar Annotator: match by term: Autism spectrum disorderClinVarPMID:25741868
Asxl2RatDevelopmental Disease  ISOASXL2 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental disorderClinVarPMID:25741868
Asxl2Ratgenetic disease  ISOASXL2 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
Asxl2Rathydrocephalus  ISOASXL2 (Homo sapiens)8554872ClinVar Annotator: match by term: Severe hydrocephalusClinVarPMID:25741868
Asxl2RatNeurodevelopmental Disorders  ISOASXL2 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Asxl2RatShashi-Pena Syndrome  ISOASXL2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Asxl2RatTatton-Brown-Rahman syndrome  ISOASXL2 (Homo sapiens)8554872ClinVar Annotator: match by term: Tatton-Brown-Rahman overgrowth syndromeClinVarPMID:24614070 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Asxl2Ratacute myeloid leukemia  ISOASXL2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27798625
Asxl2Raturinary bladder cancer  ISOASXL2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:24121791
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Asxl2RatShashi-Pena Syndrome  ISOASXL2 (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Asxl2Rat(+)-catechin multiple interactionsISOASXL2 (Homo sapiens)6480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of ASXL2 mRNACTDPMID:24763279
Asxl2Rat1,2-dimethylhydrazine multiple interactionsISOAsxl2 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ASXL2 mRNACTDPMID:22206623
Asxl2Rat1,2-dimethylhydrazine decreases expressionISOAsxl2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of ASXL2 mRNACTDPMID:22206623
Asxl2Rat1-Hydroxypyrene decreases expressionISOASXL2 (Homo sapiens)64804641-hydroxypyrene results in decreased expression of ASXL2 mRNACTDPMID:21854004
Asxl2Rat2,2',4,4'-Tetrabromodiphenyl ether multiple interactionsISOAsxl2 (Mus musculus)6480464[Flame Retardants results in increased abundance of 2 more ...CTDPMID:38995820
Asxl2Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISOAsxl2 (Mus musculus)64804642 more ...CTDPMID:31388691
Asxl2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOAsxl2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of ASXL2 mRNACTDPMID:21570461
Asxl2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of ASXL2 mRNACTDPMID:32109520
Asxl2Rat2-hydroxypropanoic acid decreases expressionISOASXL2 (Homo sapiens)6480464Lactic Acid results in decreased expression of ASXL2 mRNACTDPMID:30851411
Asxl2Rat2-methylcholine affects expressionISOASXL2 (Homo sapiens)6480464beta-methylcholine affects the expression of ASXL2 mRNACTDPMID:21179406
Asxl2Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOASXL2 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of ASXL2 mRNACTDPMID:28628672
Asxl2Rataflatoxin B1 increases expressionISOAsxl2 (Mus musculus)6480464Aflatoxin B1 results in increased expression of ASXL2 mRNACTDPMID:19770486
Asxl2Rataflatoxin B1 increases methylationISOASXL2 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of ASXL2 geneCTDPMID:27153756
Asxl2Rataristolochic acid A decreases expressionISOASXL2 (Homo sapiens)6480464aristolochic acid I results in decreased expression of ASXL2 mRNACTDPMID:33212167
Asxl2Ratarsane multiple interactionsISOASXL2 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ASXL2 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ASXL2 mRNACTDPMID:39836092
Asxl2Ratarsenic atom multiple interactionsISOASXL2 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of ASXL2 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ASXL2 mRNACTDPMID:39836092
Asxl2Ratarsenous acid increases expressionISOASXL2 (Homo sapiens)6480464Arsenic Trioxide results in increased expression of ASXL2 mRNACTDPMID:20458559
Asxl2Ratatrazine decreases expressionISOASXL2 (Homo sapiens)6480464Atrazine results in decreased expression of ASXL2 mRNACTDPMID:22378314
Asxl2Ratbenzo[a]pyrene increases expressionISOAsxl2 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of ASXL2 mRNACTDPMID:22228805
Asxl2Ratbenzo[a]pyrene decreases expressionISOASXL2 (Homo sapiens)6480464Benzo(a)pyrene results in decreased expression of ASXL2 mRNACTDPMID:30453624

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Biological Process
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Asxl2Ratadult heart development acts_upstream_of_or_withinISOAsxl2 (Mus musculus)1624291MGI:3840841 PMID:23046516RGDPMID:23046516
Asxl2Ratanimal organ morphogenesis involved_inIBAFB:FBgn0261823 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Asxl2Ratbone mineralization involved in bone maturation acts_upstream_ofISOAsxl2 (Mus musculus)1624291MGI:3840841 PMID:21490954RGDPMID:21490954
Asxl2Ratembryonic skeletal system morphogenesis acts_upstream_of_or_withinISOAsxl2 (Mus musculus)1624291MGI:3840841 PMID:19270745RGDPMID:19270745
Asxl2Ratheart development acts_upstream_of_or_withinISOAsxl2 (Mus musculus)1624291MGI:3840841 PMID:19270745RGDPMID:19270745
Asxl2Ratheart morphogenesis acts_upstream_of_or_withinISOAsxl2 (Mus musculus)1624291MGI:3840841 PMID:24860998RGDPMID:24860998
Asxl2Ratmacrophage differentiation acts_upstream_ofISOAsxl2 (Mus musculus)1624291 PMID:21490954RGDPMID:21490954
Asxl2Ratnegative regulation of transcription by RNA polymerase II acts_upstream_of_or_withinISOAsxl2 (Mus musculus)1624291MGI:3840841 PMID:23046516RGDPMID:23046516
Asxl2Ratosteoclast differentiation acts_upstream_ofISOAsxl2 (Mus musculus)1624291 PMID:21490954RGDPMID:21490954
Asxl2Ratpositive regulation of bone mineralization involved in bone maturation acts_upstream_of_or_withinISOAsxl2 (Mus musculus)1624291MGI:3840841 PMID:21490954RGDPMID:21490954
Asxl2Ratpositive regulation of fat cell differentiation involved_inISOASXL2 (Homo sapiens)1624291 PMID:21047783RGDPMID:21047783
Asxl2Ratpositive regulation of fat cell differentiation involved_inIEAUniProtKB:Q76L83 and ensembl:ENSP000003914471600115GO_REF:0000107EnsemblGO_REF:0000107
Asxl2Ratpositive regulation of lipid storage involved_inIMP 15023475PMID:24321552CACAO 
Asxl2Ratpositive regulation of macrophage differentiation acts_upstream_of_or_withinISOAsxl2 (Mus musculus)1624291 PMID:21490954RGDPMID:21490954
Asxl2Ratpositive regulation of osteoclast differentiation acts_upstream_of_or_withinISOAsxl2 (Mus musculus)1624291 PMID:21490954RGDPMID:21490954
Asxl2Ratpositive regulation of peroxisome proliferator activated receptor signaling pathway involved_inISOASXL2 (Homo sapiens)1624291 PMID:21047783RGDPMID:21047783
Asxl2Ratpositive regulation of peroxisome proliferator activated receptor signaling pathway involved_inIEAUniProtKB:Q76L83 and ensembl:ENSP000003914471600115GO_REF:0000107EnsemblGO_REF:0000107
Asxl2Ratpositive regulation of transcription by RNA polymerase II involved_inISOASXL2 (Homo sapiens)1624291 PMID:21047783RGDPMID:21047783
Asxl2Ratpositive regulation of transcription by RNA polymerase II involved_inIBAMGI:2684063 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Asxl2Ratpositive regulation of transcription by RNA polymerase II involved_inIEAUniProtKB:Q76L83 and ensembl:ENSP000003914471600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Asxl2Ratnucleoplasm located_inIEAUniProtKB:Q76L83 and ensembl:ENSP000003914471600115GO_REF:0000107EnsemblGO_REF:0000107
Asxl2Ratnucleoplasm located_inISOASXL2 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Asxl2Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Asxl2Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Asxl2Ratnucleus located_inISOAsxl2 (Mus musculus)1624291 PMID:20577743RGDPMID:20577743
Asxl2RatPR-DUB complex part_ofIBAFB:FBgn0261823 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
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1 to 10 of 10 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Reciprocal regulation of LXRα activity by ASXL1 and ASXL2 in lipogenesis. Park UH, etal., Biochem Biophys Res Commun. 2014 Jan 10;443(2):489-94. doi: 10.1016/j.bbrc.2013.11.124. Epub 2013 Dec 7.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:19270745   PMID:20577743   PMID:21047783   PMID:21490954   PMID:23046516   PMID:24860998  



Asxl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8632,090,497 - 32,234,487 (+)NCBIGRCr8
mRatBN7.2626,425,017 - 26,514,899 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl626,425,954 - 26,507,477 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0627,835,346 - 27,919,285 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl627,887,797 - 27,915,563 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0637,644,433 - 37,732,264 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4626,400,855 - 26,482,465 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1626,470,864 - 26,484,531 (+)NCBI
Celera625,902,447 - 25,987,120 (+)NCBICelera
Cytogenetic Map6q14NCBI
ASXL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38225,733,753 - 25,878,487 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl225,733,753 - 25,878,487 (-)EnsemblGRCh38hg38GRCh38
GRCh37225,956,622 - 26,101,356 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36225,815,757 - 25,954,816 (-)NCBINCBI36Build 36hg18NCBI36
Build 34225,873,909 - 26,013,007NCBI
Celera225,802,588 - 25,941,650 (-)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef225,699,339 - 25,838,712 (-)NCBIHuRef
CHM1_1225,891,914 - 26,030,899 (-)NCBICHM1_1
T2T-CHM13v2.0225,769,050 - 25,913,813 (-)NCBIT2T-CHM13v2.0
Asxl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39123,476,892 - 3,560,811 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl123,476,857 - 3,556,852 (+)EnsemblGRCm39 Ensembl
GRCm38123,426,857 - 3,510,811 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl123,426,857 - 3,506,852 (+)EnsemblGRCm38mm10GRCm38
MGSCv37123,426,884 - 3,506,849 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36123,426,901 - 3,502,468 (+)NCBIMGSCv36mm8
Celera123,353,949 - 3,434,249 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map121.81NCBI
Asxl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554697,786,154 - 7,923,500 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554697,786,030 - 7,923,739 (-)NCBIChiLan1.0ChiLan1.0
ASXL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212100,638,203 - 100,792,850 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A100,642,167 - 100,796,817 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A25,730,155 - 25,880,089 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A25,824,278 - 25,973,659 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A25,832,527 - 25,973,659 (-)Ensemblpanpan1.1panPan2
ASXL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11719,914,026 - 20,065,141 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1719,895,568 - 20,044,691 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1719,810,081 - 19,960,956 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01720,235,589 - 20,386,543 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1720,244,106 - 20,366,511 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11719,923,297 - 20,074,379 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01719,932,920 - 20,084,155 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01719,978,936 - 20,130,179 (-)NCBIUU_Cfam_GSD_1.0
Asxl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629264,237,321 - 64,375,709 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364936,463,744 - 6,594,252 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364936,463,771 - 6,602,244 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASXL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3113,044,836 - 113,180,742 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13113,044,788 - 113,184,809 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23119,991,762 - 120,173,786 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ASXL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11481,770,068 - 81,919,200 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604530,233,714 - 30,387,990 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asxl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247387,603,252 - 8,100,369 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247387,958,610 - 8,100,223 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Asxl2
729 total Variants

Predicted Target Of
Summary Value
Count of predictions:42
Count of miRNA genes:20
Interacting mature miRNAs:21
Transcripts:ENSRNOT00000015827, ENSRNOT00000061505
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 33 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6127574569Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat

1 to 10 of 33 rows
BF404323  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2626,425,745 - 26,425,935 (+)MAPPERmRatBN7.2
Rnor_6.0627,835,324 - 27,835,513NCBIRnor6.0
Rnor_5.0637,645,596 - 37,645,785UniSTSRnor5.0
RGSC_v3.4626,400,946 - 26,401,135UniSTSRGSC3.4
Celera625,902,425 - 25,902,614UniSTS
RH 3.4 Map6117.39UniSTS
Cytogenetic Map6q14UniSTS
BF399538  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2626,425,599 - 26,425,768 (+)MAPPERmRatBN7.2
Rnor_6.0627,835,178 - 27,835,346NCBIRnor6.0
Rnor_5.0637,645,450 - 37,645,618UniSTSRnor5.0
RGSC_v3.4626,400,800 - 26,400,968UniSTSRGSC3.4
Celera625,902,279 - 25,902,447UniSTS
RH 3.4 Map6116.9UniSTS
Cytogenetic Map6q14UniSTS
AU048346  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0627,856,385 - 27,856,508NCBIRnor6.0
Rnor_5.0637,666,657 - 37,666,780UniSTSRnor5.0
RGSC_v3.4626,422,007 - 26,422,131UniSTSRGSC3.4
Celera625,923,486 - 25,923,610UniSTS
Cytogenetic Map6q14UniSTS
RH140747  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2626,426,076 - 26,426,222 (+)MAPPERmRatBN7.2
Rnor_6.0627,835,655 - 27,835,800NCBIRnor6.0
Rnor_5.0637,645,927 - 37,646,072UniSTSRnor5.0
RGSC_v3.4626,401,277 - 26,401,422UniSTSRGSC3.4
Celera625,902,756 - 25,902,901UniSTS
RH 3.4 Map6117.5UniSTS
Cytogenetic Map6q14UniSTS
Asxl2DS-g-a-48f06_r1_177  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.4626,458,168 - 26,458,168 (+)RGDRGSC3.4




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 28 of 28 rows
RefSeq Transcripts XM_003754155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003754156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006225712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006225713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 28 of 28 rows

Ensembl Acc Id: ENSRNOT00000015827   ⟹   ENSRNOP00000015827
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl626,460,689 - 26,507,477 (+)Ensembl
Rnor_6.0 Ensembl627,887,797 - 27,915,563 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105980   ⟹   ENSRNOP00000081020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl626,425,954 - 26,507,477 (+)Ensembl
RefSeq Acc Id: XM_063262610   ⟹   XP_063118680
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8632,144,276 - 32,234,487 (+)NCBI
RefSeq Acc Id: XM_063262611   ⟹   XP_063118681
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8632,144,276 - 32,234,487 (+)NCBI
RefSeq Acc Id: XM_063262612   ⟹   XP_063118682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8632,090,497 - 32,234,487 (+)NCBI
RefSeq Acc Id: XM_063262613   ⟹   XP_063118683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8632,160,204 - 32,234,487 (+)NCBI
RefSeq Acc Id: XM_063262614   ⟹   XP_063118684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8632,168,740 - 32,234,487 (+)NCBI
RefSeq Acc Id: XM_063262615   ⟹   XP_063118685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8632,168,740 - 32,234,487 (+)NCBI
RefSeq Acc Id: XM_063262616   ⟹   XP_063118686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8632,168,740 - 32,234,487 (+)NCBI
RefSeq Acc Id: XM_063262617   ⟹   XP_063118687
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8632,168,738 - 32,234,487 (+)NCBI
RefSeq Acc Id: XM_063262618   ⟹   XP_063118688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8632,174,354 - 32,234,487 (+)NCBI
RefSeq Acc Id: XM_063262619   ⟹   XP_063118689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8632,200,678 - 32,234,487 (+)NCBI
RefSeq Acc Id: XM_063262620   ⟹   XP_063118690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8632,213,209 - 32,234,487 (+)NCBI
RefSeq Acc Id: XR_010052213
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8632,144,276 - 32,234,487 (+)NCBI
1 to 5 of 13 rows
1 to 5 of 13 rows
Ensembl Acc Id: ENSRNOP00000015827   ⟸   ENSRNOT00000015827
Ensembl Acc Id: ENSRNOP00000081020   ⟸   ENSRNOT00000105980
RefSeq Acc Id: XP_063118682   ⟸   XM_063262612
- Peptide Label: isoform X3
- UniProtKB: D3Z8N9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118680   ⟸   XM_063262610
- Peptide Label: isoform X1
- UniProtKB: D3Z8N9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118681   ⟸   XM_063262611
- Peptide Label: isoform X2
- UniProtKB: D3Z8N9 (UniProtKB/TrEMBL)
DEUBAD

Name Modeler Protein Id AA Range Protein Structure
AF-D3Z8N9-F1-model_v2 AlphaFold D3Z8N9 1-1225 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 20 of 20 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-38293 BioCyc
Ensembl Genes ENSRNOG00000011908 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015827 ENTREZGENE
  ENSRNOT00000015827.9 UniProtKB/TrEMBL
  ENSRNOT00000105980 ENTREZGENE
  ENSRNOT00000105980.1 UniProtKB/TrEMBL
InterPro ASX-like_PHD UniProtKB/TrEMBL
  ASX/ASX-like UniProtKB/TrEMBL
  ASXH UniProtKB/TrEMBL
  DEUBAD_dom UniProtKB/TrEMBL
NCBI Gene 313922 ENTREZGENE
PANTHER PTHR13578 UniProtKB/TrEMBL
  PTHR13578:SF11 UniProtKB/TrEMBL
Pfam ASXH UniProtKB/TrEMBL
  PHD_3 UniProtKB/TrEMBL
PhenoGen Asxl2 PhenoGen
PROSITE DEUBAD UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011908 RatGTEx
UniProt A0A8I5ZR15_RAT UniProtKB/TrEMBL
  D3Z8N9 ENTREZGENE, UniProtKB/TrEMBL
1 to 20 of 20 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-18 Asxl2  ASXL transcriptional regulator 2  Asxl2  additional sex combs like 2, transcriptional regulator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-12-02 Asxl2  additional sex combs like 2, transcriptional regulator  Asxl2  additional sex combs like transcriptional regulator 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-06-25 Asxl2  additional sex combs like transcriptional regulator 2  Asxl2  additional sex combs like 2 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Asxl2  additional sex combs like 2 (Drosophila)   Asxl2_predicted  additional sex combs like 2 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Asxl2_predicted  additional sex combs like 2 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED