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Gene: Tubgcp5 (tubulin gamma complex component 5) Rattus norvegicus

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Symbol:

Tubgcp5

Name:

tubulin gamma complex component 5

RGD ID:

1304689

Description:

Predicted to enable gamma-tubulin binding activity and microtubule binding activity. Predicted to contribute to microtubule minus-end binding activity. Predicted to be involved in meiotic cell cycle; microtubule cytoskeleton organization; and mitotic cell cycle. Predicted to be located in centrosome. Predicted to be part of gamma-tubulin ring complex. Orthologous to human TUBGCP5 (tubulin gamma complex component 5); INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; gentamycin.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

gamma-tubulin complex component 5; LOC308663; tubulin, gamma complex associated protein 5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TUBGCP5 (tubulin gamma complex component 5)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, Panther, PhylomeDB
Mus musculus (house mouse):	Tubgcp5 (tubulin, gamma complex component 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TUBGCP5 (tubulin gamma complex component 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TUBGCP5 (tubulin gamma complex component 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tubgcp5 (tubulin gamma complex component 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TUBGCP5 (tubulin gamma complex component 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TUBGCP5 (tubulin gamma complex component 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tubgcp5 (tubulin gamma complex component 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Tubgcp5 (tubulin gamma complex component 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TUBGCP5 (tubulin gamma complex component 5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tubgcp5 (tubulin, gamma complex component 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tubgcp5 (tubulin, gamma complex associated protein 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Grip128	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	tubgcp5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tubgcp5	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	115,772,294 - 115,807,947 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	115,772,384 - 115,808,438 (+)	Ensembl				GRCr8
mRatBN7.2	1	106,636,526 - 106,672,175 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	106,636,526 - 106,672,175 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	112,033,249 - 112,068,931 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	120,505,138 - 120,540,800 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	113,754,053 - 113,789,728 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	114,186,853 - 114,222,516 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	114,186,853 - 114,222,516 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	115,192,961 - 115,228,228 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	107,171,399 - 107,206,919 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	100,846,430 - 100,882,021 (+)	NCBI		Celera
RGSC_v3.1	1	107,249,811 - 107,285,247 (+)	NCBI
Cytogenetic Map	1	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

microcephaly (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,6-dinitrotoluene (EXP)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

Benoxacor (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

cadmium dichloride (ISO)

choline (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

DDE (ISO)

dexamethasone (ISO)

folic acid (ISO)

gentamycin (EXP)

GSK-J4 (ISO)

indometacin (ISO)

L-methionine (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methyl methanesulfonate (ISO)

paracetamol (ISO)

potassium chromate (ISO)

rotenone (ISO)

sodium arsenate (ISO)

sodium arsenite (EXP,ISO)

sodium fluoride (ISO)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cytoplasmic microtubule organization (IBA)

meiotic cell cycle (IBA)

microtubule cytoskeleton organization (IEA)

microtubule nucleation (IBA,IEA,ISO)

mitotic cell cycle (IBA)

spindle assembly (IBA)

Cellular Component

centrosome (IEA,ISO)

gamma-tubulin complex (IBA)

gamma-tubulin ring complex (ISO)

microtubule (IEA)

microtubule organizing center (IEA)

spindle pole (IEA)

Molecular Function

gamma-tubulin binding (IBA,IEA)

microtubule binding (ISO)

microtubule minus-end binding (IBA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11694571	PMID:21399614

Genomics

Comparative Map Data

Tubgcp5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	115,772,294 - 115,807,947 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	115,772,384 - 115,808,438 (+)	Ensembl				GRCr8
mRatBN7.2	1	106,636,526 - 106,672,175 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	106,636,526 - 106,672,175 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	112,033,249 - 112,068,931 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	120,505,138 - 120,540,800 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	113,754,053 - 113,789,728 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	114,186,853 - 114,222,516 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	114,186,853 - 114,222,516 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	115,192,961 - 115,228,228 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	107,171,399 - 107,206,919 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	100,846,430 - 100,882,021 (+)	NCBI		Celera
RGSC_v3.1	1	107,249,811 - 107,285,247 (+)	NCBI
Cytogenetic Map	1	q22	NCBI

TUBGCP5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	22,983,025 - 23,039,569 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	22,983,192 - 23,039,640 (-)	Ensembl			hg38	GRCh38
GRCh37	15	22,833,499 - 22,890,043 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	20,384,836 - 20,425,332 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	15	20,384,942 - 20,425,331	NCBI
Celera	15	1,506,523 - 1,547,034 (-)	NCBI		Celera
Cytogenetic Map	15	q11.2	NCBI
HuRef	15	1,146,027 - 1,186,592 (+)	NCBI		HuRef
CHM1_1	15	22,782,441 - 22,822,933 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	20,654,893 - 20,711,463 (-)	NCBI		T2T-CHM13v2.0

Tubgcp5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	55,443,873 - 55,481,207 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	55,443,902 - 55,481,425 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	55,794,125 - 55,831,459 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	55,794,154 - 55,831,677 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	63,049,518 - 63,086,817 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	55,662,167 - 55,699,466 (+)	NCBI		MGSCv36	mm8
Celera	7	53,147,649 - 53,185,108 (+)	NCBI		Celera
Cytogenetic Map	7	B5	NCBI
cM Map	7	33.42	NCBI

TUBGCP5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	12,327,087 - 12,374,648 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	16,060,700 - 16,101,273 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	15	20,403,757 - 20,444,851 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	20,403,757 - 20,444,851 (+)	Ensembl			panPan2	panpan1.1

TUBGCP5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	32,243,031 - 32,339,037 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	32,242,961 - 32,338,957 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	34,337,482 - 34,434,089 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	31,991,816 - 32,087,727 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	31,991,859 - 32,050,029 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	31,524,770 - 31,621,428 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	31,774,056 - 31,870,726 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	31,884,940 - 31,981,403 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tubgcp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	120,333,117 - 120,367,909 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	38,181,252 - 38,216,306 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	38,180,670 - 38,215,972 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TUBGCP5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	31,995,741 - 32,056,755 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	15	31,995,727 - 32,042,297 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TUBGCP5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	53,497,298 - 53,541,339 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	53,506,340 - 53,541,319 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666054	36,221,921 - 36,265,380 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tubgcp5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624896	2,816,262 - 2,855,161 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624896	2,818,476 - 2,855,096 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tubgcp5
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	143,370,675 - 143,406,089 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tubgcp5
120 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	55
Count of miRNA genes:	41
Interacting mature miRNAs:	42
Transcripts:	ENSRNOT00000055989
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631496	Bp97	Blood pressure QTL 97	3.08		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	115183611	176289080	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	87889942	132889942	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	102780511	182384005	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	101228864	146228864	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	111949780	210707719	Rat
1331800	Scl25	Serum cholesterol level QTL 25	3.013		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	87785026	142582336	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
9590300	Scort16	Serum corticosterone level QTL 16	4.39	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	112521556	157521556	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
61399	Tcat1	Tongue tumor resistance QTL 1	3.3		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)	1	108680016	153680016	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	91302413	136302413	Rat
631569	Bp93	Blood pressure QTL 93		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	115183611	131244255	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	102359314	153680016	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	99645382	182701046	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	111949780	210707719	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	109493780	193400781	Rat
8694370	Bw154	Body weight QTL 154	8.91	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	1	112521556	157521556	Rat
2317833	Alcrsp19	Alcohol response QTL 19	12.4	0.001	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	110389869	155389869	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
1354623	Rf46	Renal function QTL 46	3.8		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	1	111949780	160574007	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)	1	92683681	137683681	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	86993904	131993904	Rat
1641897	Alcrsp1	Alcohol response QTL 1			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	110389869	155389869	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	87558587	132558587	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	92683681	137683681	Rat
737977	Bp160	Blood pressure QTL 160		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	97582336	142582336	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	101594089	146594089	Rat
61433	Cia2	Collagen induced arthritis QTL 2	5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	100345976	145345976	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	96717367	160111531	Rat
61370	Mcs3	Mammary carcinoma susceptibility QTL 3	2.15		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	111404407	142582336	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	111949780	228180370	Rat

Markers in Region

RH137216

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	106,671,933 - 106,672,135 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	114,222,275 - 114,222,476	NCBI	Rnor6.0
Rnor_5.0	1	115,227,987 - 115,228,188	UniSTS	Rnor5.0
RGSC_v3.4	1	107,206,678 - 107,206,879	UniSTS	RGSC3.4
Celera	1	100,881,780 - 100,881,981	UniSTS
RH 3.4 Map	1	940.4	UniSTS
Cytogenetic Map	1	q22	UniSTS

AI234092

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	106,652,090 - 106,652,257 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	114,202,429 - 114,202,595	NCBI	Rnor6.0
Rnor_5.0	1	115,208,141 - 115,208,307	UniSTS	Rnor5.0
RGSC_v3.4	1	107,186,832 - 107,186,998	UniSTS	RGSC3.4
Celera	1	100,861,939 - 100,862,105	UniSTS
RH 3.4 Map	1	940.09	UniSTS
Cytogenetic Map	1	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107516	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262318	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262319	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262321	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000055989 ⟹ ENSRNOP00000052843

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	115,772,384 - 115,808,438 (+)	Ensembl
mRatBN7.2 Ensembl	1	106,636,526 - 106,672,175 (+)	Ensembl
Rnor_6.0 Ensembl	1	114,186,853 - 114,222,516 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000111705 ⟹ ENSRNOP00000084816

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	115,772,384 - 115,808,438 (+)	Ensembl
mRatBN7.2 Ensembl	1	106,636,526 - 106,672,175 (+)	Ensembl

RefSeq Acc Id:

NM_001107516 ⟹ NP_001100986

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	115,772,294 - 115,807,947 (+)	NCBI
mRatBN7.2	1	106,636,526 - 106,672,175 (+)	NCBI
Rnor_6.0	1	114,186,853 - 114,222,516 (+)	NCBI
Rnor_5.0	1	115,192,961 - 115,228,228 (+)	NCBI
RGSC_v3.4	1	107,171,399 - 107,206,919 (+)	RGD
Celera	1	100,846,430 - 100,882,021 (+)	RGD

Sequence:

show sequence

CTGCCTGAACGCTCCCGGAAACAGTCTCCAAATCTCGAAAGCCCAGTGCCGCGACAAGCAGAAC
TCTCGCGAGAACAGTCGCCGCTTAGCGGAGACCTGATAGGTAGGTCGTGGGTATGGCCCGGCCT
AAGTCGTCCGGGAGCCGGATGGACAGACAACTGGAACACGATGTGCGTGAGCTCGTCCGGCAGG
TCACTGGCCTGCAGGATGAGGCGGATTCCAACTTCCAAATGGCCCTGGACTTCGCCTGGTCCAA
CTTCAGATTTCATCGTTTCTTGGATGTCAACAGTCACAAAGTAGAAAAAACAATAGAAGGAATT
TATGAGAAACTCACCATCCATTCTGATCTCAGCAAAGCTGCTAGTTGGAAGAGATTAACTAAGG
AGTTTCTAAATGTAGCTCTTCCCAGCACAGAGAAAATAAAGACAGATACACATTATTCCATACT
GTCACTCCTTCTGTGTCTGTCTGATTCTCCTTCAAACAGCAATTATGTGGAAACACCGAGAGAG
AAAGAAGTGGAAAAGAAGGATGATTTTGACTGGGGAAAATACTTGATGGAAGGTGAAGAAGTTG
GCCTTGGTCCAGATATGGACACACCGAATTGGTCTGAAGACAGTGACGATGAAGATACCCAGCA
GCCCTTAAGCAGAGAAGACTCTGGGATACAGGTAGACAGGACTCCATTAGAAGAACAAGACCAC
AACAGAAAAGGAGGCCTTCAAGTCTGCTGGGAAGATGAGCCAGATAGCCGGAGCTGGCTGGAAC
AGCATGTAGTCCATCAGTACTGGACAACCAGGCGCTCCCGGATTCCACACAGTTCACATTTGCA
CTCCAATTTAGCTGCTGTCTGGGACCAACACCTGTACAGCAGTGACCCGCTCTATGTTCCAGAT
GACAGGGTGGTAGTTACTGAGACACAGGTCATTCGGGAAACCCTATGGTTACTTTCAGGGGTAA
AAAAGCTGTTTATATTTCAGTTGATAGATGGAAAGGTAACTGTGAGAGACAATATTATCGTAAC
TCATTTAACACACAGCTGTTTACGATCTGTGCTGGAACAGATAGCAGCATATGGCCAGGTTGTG
TTTCGGCTCCAGGAGTTCATCGATGAAGTCATGGGGCACAGCTCTGAAAGTCCATCACCAGGAA
ATGGTCCCATACCTAAGAAGACACCTGACGCTCCTTTTAGGACCTACCAGGCGTTCATGTGGGC
CCTCTACAAATACTTCATTAACTTCAAGGAGGAGCTTACAGAGATTGAGAAGAGTGTTATCAGT
AATGATACAACAATAACACTTGCAATAGTGGTGAACAAGTTGGCACCTCGATTGGCGCAGCTAA
AGGTCCTGGACAAAGTGTTTAGCACTGGAGTGGCAGAAGTTCCACCTGATACTCGCAATGTCGT
CCGGGCGTCTCACCTGCTTAACACCCTGTACAAGGCCATTCTTGAATATGACAATGTTGGAGAA
GCCTCTGAACAAACTGTCTCCCTCCTGTTCTCTCTCTGGGTGGAAACAGTGAGGCCCTACCTAC
AGACTGTAGATGAATGGATCGTCCATGGACACCTGTGGGATGGTGCAAGGGAGTTTATCATACA
GAGGAATAAAAATGTTCCGGTAAATCACAGAGACTTCTGGTACGCAACATACACACTCTATAGC
GTGTCAGAGAAGACGGAGAATGAAGACAAAGTGAGTGACAGTGCCAGTGCCAGCTCTGGCAGTG
ACCAGGGGCCCTCCAGCCGACAGCACACCATGGTGTCCTTCCTCAAGCCTGTCCTGAAGCAGAT
CATAATGGCTGGCAAGTCAATGCAACTGCTGAAGAACCTCAACTGTGCAGAGGGCTCTGCATGT
CAGGCAGCAGCCAGAGATGCAGAAAGAAAAAGCTTATATACCCTCTTTCTGGAATCTATACAGT
TACGTCTTCAGCATGGAGAAGATTCTACTACACACATTCTTAATGAAGAACAAGCAACCAAAGA
AAACCTAATAAAGATGCAGTCCATTGCTGAAAGGCACCTTGAGCTAGATGACATTCACGACCCA
CTGTTGGCCATCAACTTTGCAAGGTTGTATTTGGAGCAGAGTGACTTTCATGAGAAGTTTGCTG
GTGGTGACATATGTGTGGACAGATCATCAGAATCTGTGACCTGCCAGACTTTTGAATTAACGCT
GAGGTCTTGCCTCTATCCTCACATTGATAAACAGTATCTACATTGCTGTGGAAACCTCATGCAG
ACCTTAAAGAGAGATTTCAGGCTAGTGGAATACTTGCAGGCCATGAGGAATTTTTTCTTGATGG
AAGGTGGAGACACCATGTATGACTTCTATACTTCAATTTTTGATAAAATAAGAGAAAAGGAAAC
CTGGCAAAATGTGTCTTTTCTAAATGTTCAGCTCCAAGAAGCAGTAGGACAACGCTATCCTGAA
GACAGTTTACGTTTATCTATATCTTTTGAAAATGTTGATACAACTAAGAAGAAACTACCCGTTC
ATATCTTAGATGGTCTTACCCTAAGCTACAAGGTCCCATGGCCTGTGGACATTGTTATAAGTGT
AGAATGTCAAAAAATCTATAATCAGGTGTTCCTTCTTCTACTGCAAATAAAATGGGCAAAATAC
AGCCTGGATGTTCTACTGTTTGGTGAACTGGCTAATGCTGCTGAAAAATCCCAAGCAAAGGAAG
ACGTTCTGCGTGACCAAGATACACCCGCCCAGTTCGGACCACCAAAAGAGTCATTAAGACAACA
GATTCATCGAATGTTTCTCTTAAGAGTGAAGCTCATGCACTTTGTAAATAGTTTACACAACTAC
ATCATGACCAGGATTCTTCACAGTACCGGGCTGGAGTTTCAGCATCAAGTTGAGGAAGCCAAGG
ATTTAGATCAGTTGATTAAAATCCACTACAGGTATTTGTCAACCATCCATGACCGATGTCTGCT
GAGAGAAAAGGTCAGCTTCGTGAAAGAAGCCATTATGAAAGTGTTGAACTTGGCGCTCATGTTT
GCAGAAGGTTGGCAGGCAGGCCTAGGGGCTTGGCAAATGGAATCTATAGAGAAAATGGAATCTG
ACTTTAAAAACTGCCACATGTTTCTGGTAACCATTTTAAATAAAGCTGTCTGTAGAGGATCTTT
TCCCCACCTGGAATCTCTCGCATTGTCACTCATGGCTGGCATGGAGCAAAGTTAAATTTCTCTA
ATTTAACAAGTACCTTAGACCTCATCATCATCCATGTACACAGTCACTGTTTACAGCTGAGAAA
TAAGAACCTTTTTATTTTTATTGTTAAACTTGTCTAGATAAATGGATTGTAGGTATTTTTCTGA
AGGTTATTATCAAGAATGTAGAGTTATGTATATAATGTTGTATATCTAATTGCAAAATATATGT
GTTGTATATATTTCTTTTCTTCTAAAAGATTGACTTATTTAATGTATATGAGTATTTTGCCTGC
TTTTACATATGTGCATACCCGGTGCTCAGAGGCAATAAAAGGGTGTCAGATACCTCCTCTCTAA
AAGGTGTCTTAGATTTGACATCCCTGAAGCATTTTTATGTGCATAGAAAATCCCAAAAGAAAAA
TGTCAATGTATAAACTGTACTTTACTTAAGGCCAGCTGTTATATATCAATTTTTGGCATTTATT
AGCCAACCAGTAATATCTCAAATAAAAGTATGTATATCGTTCACTTTTCCCAC

hide sequence

RefSeq Acc Id:

XM_063262318 ⟹ XP_063118388

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	115,772,358 - 115,806,898 (+)	NCBI

RefSeq Acc Id:

XM_063262319 ⟹ XP_063118389

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	115,772,358 - 115,793,008 (+)	NCBI

RefSeq Acc Id:

XM_063262321 ⟹ XP_063118391

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	115,785,014 - 115,806,898 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100986	(Get FASTA)	NCBI Sequence Viewer
	XP_063118388	(Get FASTA)	NCBI Sequence Viewer
	XP_063118389	(Get FASTA)	NCBI Sequence Viewer
	XP_063118391	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL86461	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000052843
	ENSRNOP00000052843.4
	ENSRNOP00000084816.1

RefSeq Acc Id:

NP_001100986 ⟸ NM_001107516

- UniProtKB:

D4A2A9 (UniProtKB/TrEMBL), A6KD27 (UniProtKB/TrEMBL), A0A8I6A219 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MARPKSSGSRMDRQLEHDVRELVRQVTGLQDEADSNFQMALDFAWSNFRFHRFLDVNSHKVEKT
IEGIYEKLTIHSDLSKAASWKRLTKEFLNVALPSTEKIKTDTHYSILSLLLCLSDSPSNSNYVE
TPREKEVEKKDDFDWGKYLMEGEEVGLGPDMDTPNWSEDSDDEDTQQPLSREDSGIQVDRTPLE
EQDHNRKGGLQVCWEDEPDSRSWLEQHVVHQYWTTRRSRIPHSSHLHSNLAAVWDQHLYSSDPL
YVPDDRVVVTETQVIRETLWLLSGVKKLFIFQLIDGKVTVRDNIIVTHLTHSCLRSVLEQIAAY
GQVVFRLQEFIDEVMGHSSESPSPGNGPIPKKTPDAPFRTYQAFMWALYKYFINFKEELTEIEK
SVISNDTTITLAIVVNKLAPRLAQLKVLDKVFSTGVAEVPPDTRNVVRASHLLNTLYKAILEYD
NVGEASEQTVSLLFSLWVETVRPYLQTVDEWIVHGHLWDGAREFIIQRNKNVPVNHRDFWYATY
TLYSVSEKTENEDKVSDSASASSGSDQGPSSRQHTMVSFLKPVLKQIIMAGKSMQLLKNLNCAE
GSACQAAARDAERKSLYTLFLESIQLRLQHGEDSTTHILNEEQATKENLIKMQSIAERHLELDD
IHDPLLAINFARLYLEQSDFHEKFAGGDICVDRSSESVTCQTFELTLRSCLYPHIDKQYLHCCG
NLMQTLKRDFRLVEYLQAMRNFFLMEGGDTMYDFYTSIFDKIREKETWQNVSFLNVQLQEAVGQ
RYPEDSLRLSISFENVDTTKKKLPVHILDGLTLSYKVPWPVDIVISVECQKIYNQVFLLLLQIK
WAKYSLDVLLFGELANAAEKSQAKEDVLRDQDTPAQFGPPKESLRQQIHRMFLLRVKLMHFVNS
LHNYIMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLSTIHDRCLLREKVSFVKEAIMKVLNL
ALMFAEGWQAGLGAWQMESIEKMESDFKNCHMFLVTILNKAVCRGSFPHLESLALSLMAGMEQS

hide sequence

Ensembl Acc Id:

ENSRNOP00000052843 ⟸ ENSRNOT00000055989

Ensembl Acc Id:

ENSRNOP00000084816 ⟸ ENSRNOT00000111705

RefSeq Acc Id:	XP_063118388 ⟸ XM_063262318
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A219 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063118389 ⟸ XM_063262319
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063118391 ⟸ XM_063262321
- Peptide Label:	isoform X3

Protein Domains

Gamma tubulin complex component C-terminal Gamma tubulin complex component protein N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A2A9-F1-model_v2	AlphaFold	D4A2A9	1-1024	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690083

Promoter ID:

EPDNEW_R607

Type:

initiation region

Name:

Tubgcp5_1

Description:

tubulin, gamma complex associated protein 5

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	114,186,943 - 114,187,003	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304689	AgrOrtholog
BioCyc Gene	G2FUF-59465	BioCyc
Ensembl Genes	ENSRNOG00000011480	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000055989	ENTREZGENE
	ENSRNOT00000055989.6	UniProtKB/TrEMBL
	ENSRNOT00000111705.2	UniProtKB/TrEMBL
Gene3D-CATH	1.20.120.1900	UniProtKB/TrEMBL
InterPro	GCP_C	UniProtKB/TrEMBL
	GCP_C_sf	UniProtKB/TrEMBL
	GCP_N	UniProtKB/TrEMBL
	Spc97_Spc98	UniProtKB/TrEMBL
KEGG Report	rno:308663	UniProtKB/TrEMBL
NCBI Gene	308663	ENTREZGENE
PANTHER	GAMMA-TUBULIN COMPLEX COMPONENT 5	UniProtKB/TrEMBL
	Spc97_Spc98	UniProtKB/TrEMBL
Pfam	GCP_C_terminal	UniProtKB/TrEMBL
	GCP_N_terminal	UniProtKB/TrEMBL
PhenoGen	Tubgcp5	PhenoGen
RatGTEx	ENSRNOG00000011480	RatGTEx
UniProt	A0A8I6A219	ENTREZGENE, UniProtKB/TrEMBL
	A6KD27	ENTREZGENE, UniProtKB/TrEMBL
	D4A2A9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-06-22	Tubgcp5	tubulin gamma complex component 5	Tubgcp5	tubulin, gamma complex associated protein 5	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Tubgcp5	tubulin, gamma complex associated protein 5	Tubgcp5_predicted	tubulin, gamma complex associated protein 5 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Tubgcp5_predicted	tubulin, gamma complex associated protein 5 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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