Dctn2 (dynactin subunit 2) - Rat Genome Database

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Gene: Dctn2 (dynactin subunit 2) Rattus norvegicus
Analyze
Symbol: Dctn2
Name: dynactin subunit 2
RGD ID: 1303182
Description: Predicted to enable identical protein binding activity; protein kinase binding activity; and spectrin binding activity. Predicted to be involved in mitotic metaphase chromosome alignment and mitotic spindle organization. Predicted to act upstream of or within melanosome transport and protein localization to centrosome. Located in centrosome and kinetochore. Part of dynactin complex. Biomarker of synucleinopathy. Orthologous to human DCTN2 (dynactin subunit 2); PARTICIPATES IN mitochondria transport pathway; Huntington's disease pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: dynactin 2; dynactin 2 (p50); MGC93976
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,977,338 - 64,992,875 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl764,977,363 - 64,992,873 (+)EnsemblGRCr8
mRatBN7.2763,092,061 - 63,107,560 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,092,057 - 63,108,543 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx764,981,425 - 64,996,689 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,183,845 - 67,199,109 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0766,985,182 - 67,000,460 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,555,953 - 70,571,433 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,556,019 - 70,572,614 (+)Ensemblrn6Rnor6.0
Rnor_5.0770,730,089 - 70,745,583 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4767,223,893 - 67,239,157 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera760,232,682 - 60,247,954 (+)NCBICelera
RGSC_v3.1767,244,622 - 67,259,886 (+)NCBI
Cytogenetic Map7q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centrosome  (IBA,IDA,IEA,ISO)
ciliary basal body  (ISO)
cytoplasm  (IBA,IEA)
cytoskeleton  (IEA)
dynactin complex  (IBA,IDA,IEA,ISO)
dynein complex  (IEA)
growth cone  (ISO)
kinetochore  (IDA,ISO)
membrane  (IEA)
microtubule  (IEA)
vesicle  (ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Dynamic changes in presynaptic and axonal transport proteins combined with striatal neuroinflammation precede dopaminergic neuronal loss in a rat model of AAV alpha-synucleinopathy. Chung CY, etal., J Neurosci. 2009 Mar 18;29(11):3365-73. doi: 10.1523/JNEUROSCI.5427-08.2009.
2. Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis. Echeverri CJ, etal., J Cell Biol 1996 Feb;132(4):617-33.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Dynactin. Schroer TA, Annu Rev Cell Dev Biol. 2004;20:759-79.
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9144527   PMID:16051887   PMID:17139249   PMID:19056867   PMID:19182904   PMID:20682791   PMID:21399614   PMID:21911489   PMID:22275436   PMID:22871113   PMID:23704327   PMID:24625528  
PMID:24816561   PMID:25416956   PMID:28131823   PMID:29476059   PMID:32357304   PMID:35352799  


Genomics

Comparative Map Data
Dctn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,977,338 - 64,992,875 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl764,977,363 - 64,992,873 (+)EnsemblGRCr8
mRatBN7.2763,092,061 - 63,107,560 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,092,057 - 63,108,543 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx764,981,425 - 64,996,689 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,183,845 - 67,199,109 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0766,985,182 - 67,000,460 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,555,953 - 70,571,433 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,556,019 - 70,572,614 (+)Ensemblrn6Rnor6.0
Rnor_5.0770,730,089 - 70,745,583 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4767,223,893 - 67,239,157 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera760,232,682 - 60,247,954 (+)NCBICelera
RGSC_v3.1767,244,622 - 67,259,886 (+)NCBI
Cytogenetic Map7q22NCBI
DCTN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,530,051 - 57,547,192 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,529,633 - 57,547,242 (-)Ensemblhg38GRCh38
GRCh371257,923,834 - 57,940,975 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,210,361 - 56,227,245 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341256,210,360 - 56,227,245NCBI
Celera1257,579,926 - 57,596,808 (-)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,961,731 - 54,979,012 (-)NCBIHuRef
CHM1_11257,891,658 - 57,908,952 (-)NCBICHM1_1
T2T-CHM13v2.01257,498,291 - 57,515,431 (-)NCBIT2T-CHM13v2.0
Dctn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,102,131 - 127,117,828 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,102,237 - 127,117,819 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3810127,266,262 - 127,281,959 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,266,368 - 127,281,950 (+)Ensemblmm10GRCm38
MGSCv3710126,703,318 - 126,719,015 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3610126,669,348 - 126,684,756 (+)NCBIMGSCv36mm8
Celera10129,658,775 - 129,674,400 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.5NCBI
Dctn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554585,247,871 - 5,265,242 (-)Ensembl
ChiLan1.0NW_0049554585,247,871 - 5,264,424 (-)NCBIChiLan1.0ChiLan1.0
DCTN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,793,760 - 36,810,798 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,790,531 - 36,807,569 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,379,531 - 31,396,570 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,638,272 - 31,655,458 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,636,884 - 31,655,458 (+)EnsemblpanPan2panpan1.1
DCTN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,620,702 - 1,634,385 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,620,724 - 1,634,309 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha101,683,865 - 1,697,555 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0101,629,967 - 1,643,711 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,630,053 - 1,643,684 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,607,705 - 1,621,392 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,849,593 - 1,863,307 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,974,591 - 1,988,304 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dctn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,175,175 - 57,191,709 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,678,678 - 1,695,142 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,678,678 - 1,695,142 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCTN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,799,287 - 22,814,362 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1522,799,286 - 22,814,358 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DCTN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,438,878 - 53,456,181 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1153,439,249 - 53,456,267 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037192,507,976 - 192,525,286 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dctn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480210,412,466 - 10,429,354 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dctn2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11205,701,554 - 205,716,732 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dctn2
86 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:185
Count of miRNA genes:118
Interacting mature miRNAs:139
Transcripts:ENSRNOT00000008120
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74511390390113903Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74913799967614020Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)75170064396700643Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
1298525Cm1Cardiac mass QTL 12.7heart mass (VT:0007028)heart wet weight (CMO:0000069)756625161101625161Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73984590284845902Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73299870277998702Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73617876481178764Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)755498584105834451Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)763889858108889858Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74847504993475049Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73617876481178764Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72862457565788017Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)762963207107963207Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)763889858108889858Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
2303582Gluco53Glucose level QTL 533blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)74860308793603087Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat

Markers in Region
D10Wsu93e  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2763,107,661 - 63,107,912 (+)MAPPERmRatBN7.2
Rnor_6.0770,571,535 - 70,571,785NCBIRnor6.0
Rnor_5.0770,745,685 - 70,745,935UniSTSRnor5.0
RGSC_v3.4767,239,405 - 67,239,655UniSTSRGSC3.4
Celera760,248,201 - 60,248,451UniSTS
Cytogenetic Map7q22UniSTS
RH127945  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2763,107,133 - 63,107,316 (+)MAPPERmRatBN7.2
Rnor_6.0770,571,007 - 70,571,189NCBIRnor6.0
Rnor_5.0770,745,157 - 70,745,339UniSTSRnor5.0
RGSC_v3.4767,238,876 - 67,239,058UniSTSRGSC3.4
Celera760,247,673 - 60,247,855UniSTS
Cytogenetic Map7q22UniSTS
C87049  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2763,107,063 - 63,107,319 (+)MAPPERmRatBN7.2
Rnor_6.0770,570,937 - 70,571,192NCBIRnor6.0
Rnor_5.0770,745,087 - 70,745,342UniSTSRnor5.0
RGSC_v3.4767,238,806 - 67,239,061UniSTSRGSC3.4
Celera760,247,603 - 60,247,858UniSTS
Cytogenetic Map7q22UniSTS
RH136664  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2763,094,609 - 63,094,794 (+)MAPPERmRatBN7.2
Rnor_6.0770,558,483 - 70,558,667NCBIRnor6.0
Rnor_5.0770,732,633 - 70,732,817UniSTSRnor5.0
RGSC_v3.4767,226,352 - 67,226,536UniSTSRGSC3.4
Celera760,235,141 - 60,235,325UniSTS
Cytogenetic Map7q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000008120   ⟹   ENSRNOP00000008120
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,977,387 - 64,992,871 (+)Ensembl
mRatBN7.2 Ensembl763,092,057 - 63,107,552 (+)Ensembl
Rnor_6.0 Ensembl770,556,024 - 70,571,287 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000087495   ⟹   ENSRNOP00000069048
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,977,387 - 64,992,871 (+)Ensembl
mRatBN7.2 Ensembl763,092,057 - 63,108,543 (+)Ensembl
Rnor_6.0 Ensembl770,556,019 - 70,572,614 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098512   ⟹   ENSRNOP00000080467
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,977,387 - 64,992,871 (+)Ensembl
mRatBN7.2 Ensembl763,092,057 - 63,107,552 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099598   ⟹   ENSRNOP00000096519
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,977,387 - 64,992,871 (+)Ensembl
mRatBN7.2 Ensembl763,092,057 - 63,107,552 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102052   ⟹   ENSRNOP00000086082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,977,674 - 64,992,871 (+)Ensembl
mRatBN7.2 Ensembl763,092,406 - 63,107,413 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111694   ⟹   ENSRNOP00000081052
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,977,387 - 64,992,871 (+)Ensembl
mRatBN7.2 Ensembl763,092,159 - 63,107,555 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000125518   ⟹   ENSRNOP00000102285
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,977,387 - 64,992,871 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000145831   ⟹   ENSRNOP00000112642
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,977,451 - 64,992,873 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000152569   ⟹   ENSRNOP00000099441
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,977,363 - 64,992,873 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000154805   ⟹   ENSRNOP00000106919
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl764,977,387 - 64,992,871 (+)Ensembl
RefSeq Acc Id: NM_001004239   ⟹   NP_001004239
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,977,466 - 64,992,730 (+)NCBI
mRatBN7.2763,092,151 - 63,107,415 (+)NCBI
Rnor_6.0770,556,024 - 70,571,288 (+)NCBI
Rnor_5.0770,730,089 - 70,745,583 (+)NCBI
RGSC_v3.4767,223,893 - 67,239,157 (+)RGD
Celera760,232,682 - 60,247,954 (+)RGD
Sequence:
RefSeq Acc Id: XM_039078753   ⟹   XP_038934681
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,977,338 - 64,992,875 (+)NCBI
mRatBN7.2763,092,062 - 63,107,560 (+)NCBI
RefSeq Acc Id: XM_039078754   ⟹   XP_038934682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8764,977,382 - 64,992,875 (+)NCBI
mRatBN7.2763,092,063 - 63,107,560 (+)NCBI
RefSeq Acc Id: NP_001004239   ⟸   NM_001004239
- UniProtKB: Q6AYH5 (UniProtKB/Swiss-Prot),   A6HQT8 (UniProtKB/TrEMBL),   A0A0G2JUC7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000008120   ⟸   ENSRNOT00000008120
Ensembl Acc Id: ENSRNOP00000069048   ⟸   ENSRNOT00000087495
RefSeq Acc Id: XP_038934681   ⟸   XM_039078753
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JUC7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934682   ⟸   XM_039078754
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JUC7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000096519   ⟸   ENSRNOT00000099598
Ensembl Acc Id: ENSRNOP00000081052   ⟸   ENSRNOT00000111694
Ensembl Acc Id: ENSRNOP00000086082   ⟸   ENSRNOT00000102052
Ensembl Acc Id: ENSRNOP00000080467   ⟸   ENSRNOT00000098512
Ensembl Acc Id: ENSRNOP00000106919   ⟸   ENSRNOT00000154805
Ensembl Acc Id: ENSRNOP00000102285   ⟸   ENSRNOT00000125518
Ensembl Acc Id: ENSRNOP00000112642   ⟸   ENSRNOT00000145831
Ensembl Acc Id: ENSRNOP00000099441   ⟸   ENSRNOT00000152569

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYH5-F1-model_v2 AlphaFold Q6AYH5 1-402 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695278
Promoter ID:EPDNEW_R5780
Type:initiation region
Name:Dctn2_1
Description:dynactin subunit 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0770,556,020 - 70,556,080EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303182 AgrOrtholog
BioCyc Gene G2FUF-33756 BioCyc
Ensembl Genes ENSRNOG00000025481 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000008120 ENTREZGENE
  ENSRNOT00000008120.5 UniProtKB/Swiss-Prot
  ENSRNOT00000145831 ENTREZGENE
  ENSRNOT00000152569 ENTREZGENE
IMAGE_CLONE IMAGE:7114929 IMAGE-MGC_LOAD
InterPro Dynamitin UniProtKB/Swiss-Prot
KEGG Report rno:299850 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93976 IMAGE-MGC_LOAD
NCBI Gene 299850 ENTREZGENE
PANTHER PTHR15346 UniProtKB/Swiss-Prot
Pfam Dynamitin UniProtKB/Swiss-Prot
PhenoGen Dctn2 PhenoGen
RatGTEx ENSRNOG00000025481 RatGTEx
UniProt A0A0G2JUC7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZQ44_RAT UniProtKB/TrEMBL
  A0A8I5ZRL5_RAT UniProtKB/TrEMBL
  A0A8I6A5C2_RAT UniProtKB/TrEMBL
  A0A8I6AQX8_RAT UniProtKB/TrEMBL
  A0ABK0L5M5_RAT UniProtKB/TrEMBL
  A0ABK0LLH2_RAT UniProtKB/TrEMBL
  A0ABK0LNU3_RAT UniProtKB/TrEMBL
  A0ABK0LPE3_RAT UniProtKB/TrEMBL
  A6HQT7_RAT UniProtKB/TrEMBL
  A6HQT8 ENTREZGENE, UniProtKB/TrEMBL
  A6HQT9_RAT UniProtKB/TrEMBL
  A6HQU0_RAT UniProtKB/TrEMBL
  DCTN2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Dctn2  dynactin subunit 2  Dctn2  dynactin 2 (p50)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-10 Dctn2  dynactin 2 (p50)  Dctn2  dynactin 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Dctn2  dynactin 2      Symbol and Name status set to approved 1299863 APPROVED
2005-07-14 Dctn2  dynactin 2      Symbol and Name status set to provisional 70820 PROVISIONAL