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Gene: Lrrc36 (leucine rich repeat containing 36) Rattus norvegicus

Analyze

Symbol:

Lrrc36

Name:

leucine rich repeat containing 36

RGD ID:

1303118

Description:

Orthologous to human LRRC36 (leucine rich repeat containing 36); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

heat shock regulated 2; leucine-rich repeat-containing protein 36; LRRC36 homolog; LRRC36 homolog (human); Xlhsrf2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	50,201,944 - 50,252,338 (+)	NCBI		GRCr8
mRatBN7.2	19	33,292,074 - 33,342,426 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	33,292,074 - 33,360,141 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	40,107,667 - 40,158,016 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	40,760,992 - 40,811,344 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	43,049,777 - 43,101,984 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	37,370,469 - 37,439,048 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	37,370,498 - 37,438,488 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	48,236,102 - 48,303,988 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	35,230,297 - 35,280,568 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	35,248,467 - 35,285,442 (+)	NCBI
Celera	19	32,720,379 - 32,770,731 (+)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant dyskeratosis congenita 6 (ISO)

Chromosome 16q12 Duplication Syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (EXP)

6-propyl-2-thiouracil (EXP)

all-trans-retinoic acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

dibenz[a,h]anthracene (ISO)

furan (EXP)

mono(2-ethylhexyl) phthalate (ISO)

nickel atom (ISO)

ozone (ISO)

potassium dichromate (ISO)

progesterone (ISO)

propanal (ISO)

rotenone (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

tetraphene (ISO)

trichloroethene (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	GOA pipeline	RGD automated data pipeline
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Lrrc36
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	50,201,944 - 50,252,338 (+)	NCBI		GRCr8
mRatBN7.2	19	33,292,074 - 33,342,426 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	33,292,074 - 33,360,141 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	40,107,667 - 40,158,016 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	40,760,992 - 40,811,344 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	43,049,777 - 43,101,984 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	37,370,469 - 37,439,048 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	37,370,498 - 37,438,488 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	48,236,102 - 48,303,988 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	35,230,297 - 35,280,568 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	35,248,467 - 35,285,442 (+)	NCBI
Celera	19	32,720,379 - 32,770,731 (+)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

LRRC36
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	67,326,815 - 67,385,204 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	67,326,798 - 67,385,204 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	67,360,718 - 67,419,107 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	65,918,248 - 65,976,605 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	16	51,869,004 - 51,927,309 (+)	NCBI		Celera
Cytogenetic Map	16	q22.1	NCBI
HuRef	16	53,233,810 - 53,292,345 (+)	NCBI		HuRef
CHM1_1	16	68,768,101 - 68,826,477 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	73,121,113 - 73,179,975 (+)	NCBI		T2T-CHM13v2.0

Lrrc36
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	106,140,230 - 106,190,718 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	106,140,203 - 106,190,718 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	105,413,598 - 105,464,086 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	105,413,571 - 105,464,086 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	107,937,522 - 107,987,986 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	108,316,769 - 108,353,208 (+)	NCBI		MGSCv36	mm8
Celera	8	109,636,734 - 109,687,278 (+)	NCBI		Celera
Cytogenetic Map	8	D3	NCBI
cM Map	8	53.04	NCBI

Lrrc36
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955484	9,254,161 - 9,310,029 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955484	9,254,049 - 9,310,033 (-)	NCBI	ChiLan1.0	ChiLan1.0

LRRC36
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	76,856,018 - 76,914,901 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	82,768,726 - 82,827,584 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	47,671,996 - 47,730,683 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	67,061,278 - 67,119,652 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	67,061,328 - 67,119,535 (+)	Ensembl	panpan1.1		panPan2

LRRC36
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	82,007,337 - 82,061,344 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	82,014,920 - 82,061,559 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	81,996,447 - 82,050,915 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	82,442,094 - 82,496,583 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	82,450,144 - 82,496,798 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	82,268,226 - 82,322,693 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	81,949,334 - 82,008,253 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	82,592,784 - 82,647,499 (-)	NCBI		UU_Cfam_GSD_1.0

Lrrc36
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	41,747,763 - 41,812,502 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936475	17,776,660 - 17,840,922 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936475	17,776,654 - 17,840,979 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LRRC36
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	27,966,365 - 28,038,168 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	27,965,253 - 28,051,798 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	25,233,475 - 25,319,238 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LRRC36
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	60,072,017 - 60,126,610 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	60,071,960 - 60,126,560 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	22,821,375 - 22,879,427 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lrrc36
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624746	18,928,761 - 19,004,889 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624746	18,930,738 - 18,995,465 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Lrrc36
368 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	108
Count of miRNA genes:	90
Interacting mature miRNAs:	97
Transcripts:	ENSRNOT00000022622
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61447	Tcas1	Tongue tumor susceptibility QTL 1	6.08		tongue integrity trait (VT:0010553)	squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)	19	19220689	64220689	Rat
9590298	Uminl5	Urine mineral level QTL 5	3.59	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	19	7997750	52997750	Rat
724546	Kidm3	Kidney mass QTL 3	3.1		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	19	46226778	74246245	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	36289	74246245	Rat
2313395	Anxrr26	Anxiety related response QTL 26			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	19	44385134	74246245	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	32539615	74246245	Rat
1558656	Prcs1	Prostate cancer susceptibility QTL 1	5		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	19	31287532	51431640	Rat
9590090	Insglur8	Insulin/glucose ratio QTL 8	10.81	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	19	7997750	52997750	Rat
1331788	Rf45	Renal function QTL 45	2.818		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	19	31777888	74246245	Rat
1554318	Bmd5	Bone mineral density QTL 5	12.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	19	23188586	68188586	Rat
1549835	Tcas7	Tongue tumor susceptibility QTL 7		0.001	tongue integrity trait (VT:0010553)	squamous cell carcinoma of the head and neck tumor number (CMO:0001876)	19	41722546	74246245	Rat
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2194317	74246245	Rat
1354633	Bw28	Body weight QTL 28	6.04		body mass (VT:0001259)	body weight (CMO:0000012)	19	40727092	54856850	Rat
8552935	Pigfal10	Plasma insulin-like growth factor 1 level QTL 10	5.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	19	7997750	52997750	Rat
631840	Niddm38	Non-insulin dependent diabetes mellitus QTL 38	3.86		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	19	10329076	74246245	Rat
1358200	Insglur2	Insulin/glucose ratio QTL 2	4.1		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	19	5748064	50748064	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	32365311	74246245	Rat
724518	Uae19	Urinary albumin excretion QTL 19	5.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	24093973	69093973	Rat
61423	Cia14	Collagen induced arthritis QTL 14	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	19	10833618	74246245	Rat
2303628	Vencon9	Ventilatory control QTL 9		0.005	respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	19	23188586	68188586	Rat
9590250	Scort11	Serum corticosterone level QTL 11	23.45	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	19	7997750	52997750	Rat
2317848	Alcrsp21	Alcohol response QTL 21	1.899999976158142	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	19	20109306	65109306	Rat
1354607	Gmadr1	Adrenal mass QTL 1	5.83		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	19	40727092	54856850	Rat
7247442	Uae39	Urinary albumin excretion QTL 39			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	2194317	74246245	Rat
1354600	Salc2	Saline consumption QTL 2	9.91	0.001	drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	19	40727092	54856850	Rat

Markers in Region

D19Got25

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	33,306,529 - 33,306,665 (+)	MAPPER	mRatBN7.2
Rnor_6.0	19	37,384,957 - 37,385,092	NCBI	Rnor6.0
Rnor_5.0	19	48,250,575 - 48,250,710	UniSTS	Rnor5.0
RGSC_v3.4	19	35,244,755 - 35,244,889	RGD	RGSC3.4
RGSC_v3.4	19	35,244,754 - 35,244,889	UniSTS	RGSC3.4
RGSC_v3.1	19	35,249,636 - 35,249,770	RGD
Celera	19	32,734,835 - 32,734,970	UniSTS
RH 3.4 Map	19	358.4	UniSTS
RH 3.4 Map	19	358.4	RGD
RH 2.0 Map	19	411.8	RGD
Cytogenetic Map	19	q11	UniSTS

BE119743

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	33,342,212 - 33,342,375 (+)	MAPPER	mRatBN7.2
Rnor_6.0	19	37,420,639 - 37,420,801	NCBI	Rnor6.0
Rnor_5.0	19	48,286,256 - 48,286,418	UniSTS	Rnor5.0
RGSC_v3.4	19	35,280,355 - 35,280,517	UniSTS	RGSC3.4
Celera	19	32,770,518 - 32,770,680	UniSTS
RH 3.4 Map	19	362.92	UniSTS
Cytogenetic Map	19	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	90	89	58	25	58	6	217	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001004088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255503	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255504	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255507	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255508	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255509	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097830	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097831	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097832	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278122	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278124	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063278125	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC116220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY248698	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000022622

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	33,292,074 - 33,342,426 (+)	Ensembl
Rnor_6.0 Ensembl	19	37,370,498 - 37,438,488 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093004

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	19	37,435,827 - 37,438,308 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107718 ⟹ ENSRNOP00000087275

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	33,292,074 - 33,360,141 (+)	Ensembl

RefSeq Acc Id:

NM_001004088 ⟹ NP_001004088

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,201,987 - 50,252,338 (+)	NCBI
mRatBN7.2	19	33,292,074 - 33,342,426 (+)	NCBI
Rnor_6.0	19	37,370,501 - 37,420,852 (+)	NCBI
Rnor_5.0	19	48,236,102 - 48,303,988 (+)	NCBI
RGSC_v3.4	19	35,230,297 - 35,280,568 (+)	RGD
Celera	19	32,720,379 - 32,770,731 (+)	RGD

Sequence:

show sequence

AGGTGAGCGGCGGGAGCGAATGGCGGAGCAATGGGATCTGGACGAGGAGTGCCTCCGCCGCCTG
GGGGCGCTGACCCTCGAGCAGCCGGAACTGGTGGAGTCTCTCTCATTGCAGGGATCTTATGCTG
GAAAAATCCACTCTATTGGTGATGCCTTCAGAAATTTCAAAAATCTCCGATCCTTAGATTTATC
AAGGAATTTGATCACTAGTCTGAAGGGCATCCAGTATCTATGTTCACTCCAAGATCTGAACTTA
TATTATAACAACATTCCTTCATTAGTGGAGGTGTCCCGACTACAGCCCTTACCCTTCCTCAAAG
AACTAGATTTGAGACTCAATCCTGTTGTAAGGAAAGATACAGATTATAGGCTCTTTGCTGTGTA
CACACTGCAAATGCTGGAGAAACTGGATGACCGAGCTGTCCGTGACAGTGAGAGGAGAGCGGCC
AAGCTACATTTCAGTCAGTTGGGCAGCAGTGAAAATTTTCTCCTAGAGGTGGAAAAAAGCTCTA
GGGAGAAGACAATGAAAAACTGTGTGACAGATGAGGGCCCTGCATCACACGTCAGTTCTGAGGT
TGACACCAGAATGGAAACAGACTCAAACAAAGGACTTTTTATTTCCTTCCCCAACCGGGAAATA
AAGGATTCCCTAGCAAGCATTTGTGCAACCCAGGGCAGTGGCACACCAGCTCAGAAATTAGACG
TTTTTCCACTGGAGACACAGATGCAGGAAGCAACAAGAAGGGAGACAAGTGACCTCCACCAGGA
AGATGGATTGGAACTCAGGCATTACTCGCCTCATCAGGGCACAGTCCGATCTCCAGAGAAGATG
ACAAGAGATGGATACCGAGTATCTTTTTTAGACACTAAGTCTTCAGGTTCTTCTCCAGTAAAGG
ACTTGATACCAAAACCTGATGCCTATCCGTGTACCCATGATGCCTCTTTGGGTAAACGTCTGGA
TGTGGGTGATTCTAACCAGATCCTTCCCTGCCAATTACCTTCTGGTGTTTGTCTGGACCATTAT
GATAATCATTATTCTCAAACTCTTTGCCTGCACGGAAGTCTTGTCAAAAGGCCTCAAAAAGGCA
AGTACTATCGAGAATACAGCACAAAGCCTTCCAATGATAAAAAGGCCGCTTCATCCCTTTCCTG
TGGAGACCTGCTAACATCCCTGTCAAACCCTGACTGCAGCACAGGAAGGCCATTGAAGCTCAGT
TCAGATCTCTATGCCACAACCCGTTTCAACAGTGACCATGCTCTGCTGGCCAATGTAGAGCAAC
AGCTGTCCAGCCTCGGTGATTTTGCACCAGCACCTGGTTCCTTCCCAAGCAACCCTGCCCTAGG
AAATTCTCTGCGGACACTGCTGTTGCCTCCTGGGACTCCAGAAAACAGAGAGATTCCAACTAAG
AGGTCATTAAGCCCTTCAAGGAGAGGATTCAAGCGGAAGGACAATATCCTTGCCAACCTGAATC
TGAAACGTGGTTTCCAAGATGCTACAGGCAGCGAGGTGCAACCTTTCTCTAGTGACCTGGGCAG
TTTGCATGGTTTATCAGGAAACCGTAGTCCCCCGATCTCTGCCAGAACACCCCACGTAGCCACT
GTCCTCAGACAGCTCCTGGAGCTGGTGGATAAGCACTGGAATGGTTCTGGCTCCCTTCTCCTCA
ACAAGAAGTTTCTTGGTCCTGCCAGAGATTTGCTCCTGTCCTTGGTGGTGCCTGCACCTCCCCA
GCAGTGGCATCGCTCGCTGCTTGACGACAAGACAGGGAGAGCCTTGCACTGGAGGGAGACGGAG
CTAAAGGAAGCAGGGCAGCTGGTTCCCAGTGATGTGGAAAGTTTGAAGCAAAAACTGGTCAAAG
TGTTGGAAGAAAACCTTATTTTGTCAGAAAAAATTCAGCAGTTGGAGGGAGCTGCTGCCACCTC
GGTTGTGAGTGGGCACCCATCTCACACACACGATGATCTTCTGCACAAAAACCAACAGCTGACC
ATACAGGTGGCTTGCCTGAACCAGGAGCTGACTCAGCTGAAAAGGCTGGAGGAGACAGTTGCTC
TTCTCCATGAGAGTCAGAGGTCCCTGGTGGTAACTAATGAGTATCTGCTGCAGCAGCTGAATAA
AGAGCAGAAAGGTTATTCCGGGAAATCGCTCCTGCCTCCTGAGAAGACTCATCCTTTGGGGAGA
TTGTCGCCCTTTGGGAAAAGCACTCTGTCTTCCTCCTCACCAACGGTACACAACACGGGTCAGT
ACCTAATACAGAGTGTCTCAGAAGCTGACCCTGAGCCTAGTCTGTGGAGCTAGCACCACAGCCT
TCCCCACCACTCCCTCACCCATGGAGGTAACTCAGCCCTACTGTCCCTGTAGTGGATACTGGTG
TTTATCCCCAAAGATTAAGAAAAACTTATTATGATTACATTA

hide sequence

RefSeq Acc Id:

XM_039097830 ⟹ XP_038953758

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,217,584 - 50,252,338 (+)	NCBI
mRatBN7.2	19	33,307,671 - 33,342,426 (+)	NCBI

RefSeq Acc Id:

XM_039097831 ⟹ XP_038953759

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,217,584 - 50,252,338 (+)	NCBI
mRatBN7.2	19	33,307,671 - 33,342,426 (+)	NCBI

RefSeq Acc Id:

XM_039097832 ⟹ XP_038953760

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,241,139 - 50,252,338 (+)	NCBI
mRatBN7.2	19	33,331,237 - 33,342,426 (+)	NCBI

RefSeq Acc Id:

XM_063278122 ⟹ XP_063134192

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,201,944 - 50,252,338 (+)	NCBI

RefSeq Acc Id:

XM_063278123 ⟹ XP_063134193

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,201,955 - 50,252,338 (+)	NCBI

RefSeq Acc Id:

XM_063278124 ⟹ XP_063134194

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,217,019 - 50,252,338 (+)	NCBI

RefSeq Acc Id:

XM_063278125 ⟹ XP_063134195

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,201,958 - 50,248,370 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001004088	(Get FASTA)	NCBI Sequence Viewer
	XP_038953758	(Get FASTA)	NCBI Sequence Viewer
	XP_038953759	(Get FASTA)	NCBI Sequence Viewer
	XP_038953760	(Get FASTA)	NCBI Sequence Viewer
	XP_063134192	(Get FASTA)	NCBI Sequence Viewer
	XP_063134193	(Get FASTA)	NCBI Sequence Viewer
	XP_063134194	(Get FASTA)	NCBI Sequence Viewer
	XP_063134195	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAP23995	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000087275.1
	ENSRNOP00000088526.1

RefSeq Acc Id:

NP_001004088 ⟸ NM_001004088

- UniProtKB:

A0A8I6GH65 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEQWDLDEECLRRLGALTLEQPELVESLSLQGSYAGKIHSIGDAFRNFKNLRSLDLSRNLITS
LKGIQYLCSLQDLNLYYNNIPSLVEVSRLQPLPFLKELDLRLNPVVRKDTDYRLFAVYTLQMLE
KLDDRAVRDSERRAAKLHFSQLGSSENFLLEVEKSSREKTMKNCVTDEGPASHVSSEVDTRMET
DSNKGLFISFPNREIKDSLASICATQGSGTPAQKLDVFPLETQMQEATRRETSDLHQEDGLELR
HYSPHQGTVRSPEKMTRDGYRVSFLDTKSSGSSPVKDLIPKPDAYPCTHDASLGKRLDVGDSNQ
ILPCQLPSGVCLDHYDNHYSQTLCLHGSLVKRPQKGKYYREYSTKPSNDKKAASSLSCGDLLTS
LSNPDCSTGRPLKLSSDLYATTRFNSDHALLANVEQQLSSLGDFAPAPGSFPSNPALGNSLRTL
LLPPGTPENREIPTKRSLSPSRRGFKRKDNILANLNLKRGFQDATGSEVQPFSSDLGSLHGLSG
NRSPPISARTPHVATVLRQLLELVDKHWNGSGSLLLNKKFLGPARDLLLSLVVPAPPQQWHRSL
LDDKTGRALHWRETELKEAGQLVPSDVESLKQKLVKVLEENLILSEKIQQLEGAAATSVVSGHP
SHTHDDLLHKNQQLTIQVACLNQELTQLKRLEETVALLHESQRSLVVTNEYLLQQLNKEQKGYS
GKSLLPPEKTHPLGRLSPFGKSTLSSSSPTVHNTGQYLIQSVSEADPEPSLWS

hide sequence

RefSeq Acc Id:	XP_038953758 ⟸ XM_039097830
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_038953759 ⟸ XM_039097831
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038953760 ⟸ XM_039097832
- Peptide Label:	isoform X7

Ensembl Acc Id:

ENSRNOP00000087275 ⟸ ENSRNOT00000107718

RefSeq Acc Id:	XP_063134192 ⟸ XM_063278122
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063134193 ⟸ XM_063278123
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063134195 ⟸ XM_063278125
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063134194 ⟸ XM_063278124
- Peptide Label:	isoform X3

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303118	AgrOrtholog
BioCyc Gene	G2FUF-5831	BioCyc
Ensembl Genes	ENSRNOG00000016854	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000022622.6	UniProtKB/TrEMBL
	ENSRNOT00000107718.1	UniProtKB/TrEMBL
Gene3D-CATH	3.80.10.10	UniProtKB/TrEMBL
InterPro	CEP72-like	UniProtKB/TrEMBL
	Leu-rich_rpt	UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:361394	UniProtKB/TrEMBL
NCBI Gene	361394	ENTREZGENE
PANTHER	HEAT SHOCK REGULATED 2	UniProtKB/TrEMBL
	LEUCINE-RICH REPEAT-CONTAINING PROTEIN 36	UniProtKB/TrEMBL
Pfam	LRR_9	UniProtKB/TrEMBL
PhenoGen	Lrrc36	PhenoGen
PROSITE	LRR	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000016854	RatGTEx
Superfamily-SCOP	L domain-like	UniProtKB/TrEMBL
UniProt	A0A8I6A5K1_RAT	UniProtKB/TrEMBL
	A0A8I6GH65	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Lrrc36	leucine rich repeat containing 36	Lrrc36	LRRC36 homolog (human)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-04-14	Lrrc36	LRRC36 homolog (human)	Xlhsrf2	heat shock regulated 2	Symbol and Name updated to reflect Human and Mouse nomenclature	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar