Advanced Search (OLGA)

Gene: Ankra2 (ankyrin repeat family A member 2) Rattus norvegicus

Analyze

Symbol:

Ankra2

Name:

ankyrin repeat family A member 2

RGD ID:

1303108

Description:

Predicted to enable enzyme binding activity and low-density lipoprotein particle receptor binding activity. Predicted to be involved in regulation of protein-containing complex assembly. Predicted to be located in cytosol; membrane; and nucleus. Predicted to be part of 3M complex. Orthologous to human ANKRA2 (ankyrin repeat family A member 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ANKRA; ankyrin repeat family A protein 2; ankyrin repeat family A protein 2-like; ankyrin repeat, family A (RFXANK-like), 2; ankyrin-repeat family A protein; LOC100910438; LOC294679; MGC94130; SLO-interacting ankyrin-containing protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ANKRA2 (ankyrin repeat family A member 2)	RGD	RGD
Mus musculus (house mouse):	Ankra2 (ankyrin repeat family A member 2)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Ankra2 (ankyrin repeat family A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ANKRA2 (ankyrin repeat family A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ANKRA2 (ankyrin repeat family A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ankra2 (ankyrin repeat family A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ANKRA2 (ankyrin repeat family A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ANKRA2 (ankyrin repeat family A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ankra2 (ankyrin repeat family A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ankra2 (ankyrin repeat family A member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ANKRA2 (ankyrin repeat family A member 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ankra2 (ankyrin repeat family A member 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ankra2 (ankyrin repeat, family A (RFXANK-like), 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG5846	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG5846	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ankra2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ankra2	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	31,347,158 - 31,358,002 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	31,347,090 - 31,364,394 (+)	Ensembl				GRCr8
mRatBN7.2	2	29,612,867 - 29,623,748 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	29,612,925 - 29,623,730 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	36,670,264 - 36,680,899 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	34,764,617 - 34,775,252 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	29,582,502 - 29,593,137 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	82,407,601 - 82,418,229 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	82,407,598 - 82,418,425 (-)	Ensembl			rn6	Rnor6.0
Rnor_6.0 Ensembl	2	28,370,373 - 28,381,311 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	82,381,970 - 82,392,805 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	28,853,907 - 28,864,539 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	25,651,376 - 25,662,008 (+)	NCBI		Celera
RGSC_v3.1	2	28,774,275 - 28,784,904 (+)	NCBI
Cytogenetic Map	2	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

6-propyl-2-thiouracil (EXP)

actinomycin D (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP)

cadmium dichloride (ISO)

camptothecin (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroacetaldehyde (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

clodronic acid (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

dioxygen (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

elemental selenium (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

fenofibrate (ISO)

folic acid (ISO)

formaldehyde (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

ifosfamide (ISO)

lead(0) (ISO)

menadione (ISO)

methimazole (EXP)

methotrexate (ISO)

methyl methanesulfonate (ISO)

Nutlin-3 (ISO)

okadaic acid (ISO)

paracetamol (EXP)

potassium chromate (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

SB 431542 (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

simvastatin (EXP)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

tert-butyl hydroperoxide (ISO)

triptonide (ISO)

valproic acid (ISO)

vincristine (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

regulation of gene expression (IBA)

regulation of protein-containing complex assembly (ISO)

Cellular Component

3M complex (ISO)

cytoplasm (IEA,ISO)

cytosol (ISO)

membrane (ISO)

nucleus (IBA,ISO)

plasma membrane (ISO)

protein-containing complex (ISO)

Molecular Function

histone deacetylase binding (IEA,ISO)

low-density lipoprotein particle receptor binding (ISO)

protein binding (ISO)

protein kinase binding (ISO)

ubiquitin protein ligase binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11095640	PMID:15616191	PMID:16236793	PMID:20873783	PMID:22649097	PMID:25752541

Genomics

Comparative Map Data

Ankra2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	31,347,158 - 31,358,002 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	31,347,090 - 31,364,394 (+)	Ensembl				GRCr8
mRatBN7.2	2	29,612,867 - 29,623,748 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	29,612,925 - 29,623,730 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	36,670,264 - 36,680,899 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	34,764,617 - 34,775,252 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	29,582,502 - 29,593,137 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	82,407,601 - 82,418,229 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	82,407,598 - 82,418,425 (-)	Ensembl			rn6	Rnor6.0
Rnor_6.0 Ensembl	2	28,370,373 - 28,381,311 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	82,381,970 - 82,392,805 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	28,853,907 - 28,864,539 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	25,651,376 - 25,662,008 (+)	NCBI		Celera
RGSC_v3.1	2	28,774,275 - 28,784,904 (+)	NCBI
Cytogenetic Map	2	q12	NCBI

ANKRA2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	73,552,190 - 73,565,639 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	73,552,190 - 73,565,712 (-)	Ensembl			hg38	GRCh38
GRCh37	5	72,848,015 - 72,861,464 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	72,883,919 - 72,897,254 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	72,883,918 - 72,897,254	NCBI
Celera	5	68,743,316 - 68,756,798 (-)	NCBI		Celera
Cytogenetic Map	5	q13.2	NCBI
HuRef	5	68,053,527 - 68,067,013 (-)	NCBI		HuRef
CHM1_1	5	72,280,757 - 72,294,244 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	74,033,518 - 74,046,951 (-)	NCBI		T2T-CHM13v2.0

Ankra2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	98,399,584 - 98,411,262 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	98,399,582 - 98,411,262 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	13	98,263,076 - 98,274,754 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	98,263,074 - 98,274,754 (+)	Ensembl			mm10	GRCm38
MGSCv37	13	99,033,197 - 99,043,868 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	13	99,363,399 - 99,374,070 (+)	NCBI		MGSCv36	mm8
Celera	13	101,913,404 - 101,924,071 (+)	NCBI		Celera
Cytogenetic Map	13	D1	NCBI
cM Map	13	51.89	NCBI

Ankra2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	27,035,850 - 27,045,633 (+)	Ensembl
ChiLan1.0	NW_004955425	27,035,850 - 27,045,253 (+)	NCBI	ChiLan1.0	ChiLan1.0

ANKRA2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	41,754,478 - 41,767,863 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	39,908,564 - 39,921,497 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	41,753,093 - 41,766,440 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	42,351,611 - 42,364,983 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	42,351,611 - 42,364,983 (+)	Ensembl			panPan2	panpan1.1

ANKRA2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	56,364,768 - 56,378,092 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	56,365,207 - 56,377,835 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	53,341,048 - 53,354,269 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	56,887,010 - 56,900,250 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	56,887,002 - 56,900,333 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	53,947,425 - 53,960,649 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	54,715,349 - 54,728,574 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	55,606,626 - 55,619,920 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ankra2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	187,825,063 - 187,835,154 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936549	3,023,200 - 3,033,932 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936549	3,023,519 - 3,033,910 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ANKRA2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	82,702,179 - 82,715,345 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	82,702,176 - 82,715,340 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	84,227,163 - 84,240,203 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ANKRA2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	67,914,948 - 67,928,156 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	67,914,807 - 67,928,632 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666049	16,685,205 - 16,698,570 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ankra2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624924	1,456,259 - 1,466,766 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624924	1,456,299 - 1,466,858 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ankra2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	198,323,943 - 198,334,541 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ankra2
143 total Variants

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10755430	Coatc6	Coat color QTL 6		0.02576	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	13325041	58325041	Rat
7387318	Stl32	Serum triglyceride level QTL 32	3.2	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	24117813	69117813	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
738010	Lnnr3	Liver neoplastic nodule remodeling QTL 3	2.94		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	2	1	42977529	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
9590080	Insglur4	Insulin/glucose ratio QTL 4	28.7	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	2	6152767	51152767	Rat
1579916	Bp270	Blood pressure QTL 270		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	16051883	61051883	Rat
731167	Glom4	Glomerulus QTL 4	2.4	0.0082	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	2	22038044	67038044	Rat
731166	Mamtr2	Mammary tumor resistance QTL 2		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	9623581	54623581	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	27148328	145807373	Rat
9590095	Sffal3	Serum free fatty acids level QTL 3	6.78	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	2	28889991	73889991	Rat
1331764	Bp205	Blood pressure QTL 205	3.476		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	14368707	59368707	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1600379	Mcs18	Mammary carcinoma susceptibility QTL 18	2.6		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	9623581	44538110	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	7605533	104774005	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	28652666	83465677	Rat
1578664	Bmd9	Bone mineral QTL density 9	5		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	5736325	50736325	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	28652666	139067443	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
731184	Mamtr4	Mammary tumor resistance QTL 4		0.0003	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	18227137	63227137	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
1354603	Bp243	Blood pressure QTL 243	3.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	28652666	73652666	Rat

Markers in Region

RH141618

Rat Assembly	Chr	Position (strand)	Source	JBrowse
RGSC_v3.4	X	99,297,419 - 99,297,590	UniSTS	RGSC3.4
Celera	X	77,195,325 - 77,195,496	UniSTS
RH 3.4 Map	X	733.02	UniSTS
Cytogenetic Map	2	q12	UniSTS

AA891585

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	75,939,546 - 75,939,737 (-)	MAPPER	mRatBN7.2
mRatBN7.2	X	75,939,546 - 75,939,737 (+)	MAPPER	mRatBN7.2
mRatBN7.2	2	29,623,256 - 29,623,447 (-)	MAPPER	mRatBN7.2
mRatBN7.2	2	29,623,256 - 29,623,447 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	28,380,777 - 28,380,967	NCBI	Rnor6.0
Rnor_6.0	X	82,407,898 - 82,408,088	NCBI	Rnor6.0
Rnor_5.0	X	82,382,267 - 82,382,457	UniSTS	Rnor5.0
Rnor_5.0	2	47,482,627 - 47,482,817	UniSTS	Rnor5.0
RGSC_v3.4	X	99,295,748 - 99,295,938	UniSTS	RGSC3.4
RGSC_v3.4	2	28,864,048 - 28,864,238	UniSTS	RGSC3.4
Celera	2	25,661,517 - 25,661,707	UniSTS
Celera	X	77,193,654 - 77,193,844	UniSTS
RH 3.4 Map	2	33.7	UniSTS
Cytogenetic Map	2	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	1	18	55	1	3	1	69	1	145	97	11	54	38	35	2	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001416756	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_207595	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006257186	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281493	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281494	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY566568	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC081975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231969	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000022525 ⟹ ENSRNOP00000022525

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	80,055,681 - 80,057,740 (-)	Ensembl
mRatBN7.2 Ensembl	X	75,939,719 - 75,941,326 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000073183 ⟹ ENSRNOP00000065662

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	31,347,090 - 31,364,394 (+)	Ensembl
mRatBN7.2 Ensembl	2	29,612,925 - 29,623,730 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000136863 ⟹ ENSRNOP00000098976

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	31,347,090 - 31,357,726 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000147507 ⟹ ENSRNOP00000107996

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	31,347,090 - 31,358,621 (+)	Ensembl

RefSeq Acc Id:

NM_001416756 ⟹ NP_001403685

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	31,347,158 - 31,358,002 (+)	NCBI
mRatBN7.2	2	29,612,904 - 29,623,748 (+)	NCBI

RefSeq Acc Id:

NM_207595 ⟹ NP_997478

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	31,347,158 - 31,358,002 (+)	NCBI
mRatBN7.2	2	29,612,904 - 29,623,748 (+)	NCBI
Rnor_6.0	X	82,407,601 - 82,418,229 (-)	NCBI
Rnor_5.0	X	82,381,970 - 82,392,805 (-)	NCBI
RGSC_v3.4	2	28,853,907 - 28,864,539 (+)	RGD
Celera	2	25,651,376 - 25,662,008 (+)	NCBI

Sequence:

show sequence

CGCTCTGGGTAGTCATATCACCCGCCGGACCGGCCCCTGTCCCCGGAACCGCTCACGGTGCGGG
AGCGGGTGTCACCCCGCGGCCATAGAGCGGGAACGCCCGCCGGGACACCTGTCGCTTATACTTT
ACTATCTCAATTCCAGTAAAATACTGGATAACATCCTTGGAAAAAAAAAGAAAAGAAATCATGA
AGAAATGTTTTAATTATTAAAACCATGGCTACATCTGCAAATCTGGACATTGGGGCCCAACTGG
TCGTGGAAGAGTGTCCCAGCAGCTATGGCCTCTCTGGGATGCCAGACATCAAAATAGAGCACCA
GCCAGACCCAAACTCAGATGAAGGGTCAGCTCAGGGAGTCGCCATGGGGATGAAGTTCATACTG
CCAAACCGATTTGATATGAACGTGTGCTCTCGCTTTGTGAAGTCCTTAAACGAAGAGGATAGTA
AAAATATTCAAGATCAAGTTAACTCTGACCTGGAGGTGGCGTCTGTCTTATTTAAAGCTGAATG
CAATATCCATACCTCTCCTTCTCCTGGAATTCAAGTAAGGCACGTCTACACACCCTCTACAACT
AAACATTTCTCACCCATAAAACAGTCAACTACTTTAACCAACAAGCACAGGGGAAACGAGGTCT
CCACCACACCTCTGTTAGCAAATTCTCTGTCTGTTCACCAGTTGGCAGCTCAGGGAGAGATGCT
CTACCTGGCTACTCGTATTGAACAAGAAAATGTTATCAATCACACGGATGAAGAAGGATTTACT
CCCCTGATGTGGGCTGCGGCACACGGGCAAATAGCTGTGGTAGAATTCCTCCTTCAGAACGGTG
CAGATCCCCAGCTCTTAGGAAAAGGTCGAGAAAGTGCCCTGTCGTTGGCCTGCAGTAAGGGCTA
CACAGACATTGTCAAAATGCTGCTAGACTGTGGAGTTGACGTAAATGAGTATGACTGGAACGGA
GGCACCCCTTTGCTTTATGCTGTCCACGGGAACCACGGGAAGTGCGTGAAGATGCTGTTGGAAA
ATGGAGCTGACCCAACAATTGAAACAGACTCTGGCTATAATTCTATGGACTTGGCTGTAGCTCT
GGGCTACAGAAGTGTTCAACAGGTCATTGAGTCACACCTGCTGAAGCTGCTTCAGAACATCAAG
GAGTGACGGACTCCTCAGAAAAGGCCACCTGCCCTTCTCAGCCCTGGGTCCTTAATGATAGTTT
TGTTTACGTGTAAATTTTTATAGTTCTGTTTGAGTGTAAATTTTTATCTCAGTTGCAATATTTG
CTGGTTTTTAGTGAGTTTTAATACATATTCCTCTGGATAATTCACTTGTCTATAATAAAATTAA
TCCTGATTTTTTAAATAAATGTGTCTTACTATATATTAAGATTATTAATTAATGTTTTCTGGCA
TGTAACCTTTTATGGTACAGGTGTTTGTATGTTTTGTATCAAGGATCACAATGACACTTTAAGA
AAACTCCATCTTGTTTCTCTCCACTCCTGTATTAACTTTGACTTTCACAGGACTCACTGTAAGT
CTGTGGGGAAAATAATGTTCTTGTTGAATTAAAGAGTACTCAGTGTGATGGTTTACAAAATCAT
GTTTAAATAAAGTACCTTTCTGTCTGTCCGCAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039101921 ⟹ XP_038957849

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	31,347,351 - 31,358,002 (+)	NCBI
mRatBN7.2	2	29,612,867 - 29,623,748 (+)	NCBI

RefSeq Acc Id:

XM_063281493 ⟹ XP_063137563

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	31,347,351 - 31,356,964 (+)	NCBI

RefSeq Acc Id:

XM_063281494 ⟹ XP_063137564

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	31,350,062 - 31,358,002 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001403685	(Get FASTA)	NCBI Sequence Viewer
	NP_997478	(Get FASTA)	NCBI Sequence Viewer
	XP_038957849	(Get FASTA)	NCBI Sequence Viewer
	XP_063137563	(Get FASTA)	NCBI Sequence Viewer
	XP_063137564	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH81975	(Get FASTA)	NCBI Sequence Viewer
	AAS68635	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000022525.3
	ENSRNOP00000065662.3
	ENSRNOP00000098976
	ENSRNOP00000098976.1
	ENSRNOP00000107996
	ENSRNOP00000107996.1

RefSeq Acc Id:	NP_997478 ⟸ NM_207595
- Peptide Label:	isoform 1
- UniProtKB:	Q6Q287 (UniProtKB/TrEMBL), M0R870 (UniProtKB/TrEMBL)
- Sequence:	show sequence MATSANLDIGAQLVVEECPSSYGLSGMPDIKIEHQPDPNSDEGSAQGVAMGMKFILPNRFDMNV CSRFVKSLNEEDSKNIQDQVNSDLEVASVLFKAECNIHTSPSPGIQVRHVYTPSTTKHFSPIKQ STTLTNKHRGNEVSTTPLLANSLSVHQLAAQGEMLYLATRIEQENVINHTDEEGFTPLMWAAAH GQIAVVEFLLQNGADPQLLGKGRESALSLACSKGYTDIVKMLLDCGVDVNEYDWNGGTPLLYAV HGNHGKCVKMLLENGADPTIETDSGYNSMDLAVALGYRSVQQVIESHLLKLLQNIKE hide sequence

RefSeq Acc Id:	XP_038957849 ⟸ XM_039101921
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000022525 ⟸ ENSRNOT00000022525

Ensembl Acc Id:

ENSRNOP00000065662 ⟸ ENSRNOT00000073183

RefSeq Acc Id:	NP_001403685 ⟸ NM_001416756
- Peptide Label:	isoform 2
- UniProtKB:	A6I539 (UniProtKB/TrEMBL), A6I538 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137563 ⟸ XM_063281493
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063137564 ⟸ XM_063281494
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000107996 ⟸ ENSRNOT00000147507

Ensembl Acc Id:

ENSRNOP00000098976 ⟸ ENSRNOT00000136863

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6Q287-F1-model_v2	AlphaFold	Q6Q287	1-313	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701913

Promoter ID:

EPDNEW_R12437

Type:

single initiation site

Name:

Ankra2_1

Description:

ankyrin repeat family A member 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	82,418,425 - 82,418,485	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303108	AgrOrtholog
BioCyc Gene	G2FUF-54731	BioCyc
Ensembl Genes	ENSRNOG00000016622	Ensembl, UniProtKB/TrEMBL
	ENSRNOG00000048118	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000022525.8	UniProtKB/TrEMBL
	ENSRNOT00000073183.4	UniProtKB/TrEMBL
	ENSRNOT00000136863	ENTREZGENE
	ENSRNOT00000136863.1	UniProtKB/TrEMBL
	ENSRNOT00000147507	ENTREZGENE
	ENSRNOT00000147507.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.20	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7126874	IMAGE-MGC_LOAD
InterPro	Ankyrin_rpt	UniProtKB/TrEMBL
	Ankyrin_rpt-contain_sf	UniProtKB/TrEMBL
MGC_CLONE	MGC:94130	IMAGE-MGC_LOAD
NCBI Gene	294679	ENTREZGENE
PANTHER	ANKYRIN REPEAT FAMILY A	UniProtKB/TrEMBL
	ANKYRIN REPEAT FAMILY A PROTEIN 2	UniProtKB/TrEMBL
Pfam	Ank	UniProtKB/TrEMBL
	Ank_2	UniProtKB/TrEMBL
PhenoGen	Ankra2	PhenoGen
PRINTS	ANKYRIN	UniProtKB/TrEMBL
PROSITE	ANK_REP_REGION	UniProtKB/TrEMBL
	ANK_REPEAT	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000016622	RatGTEx
	ENSRNOG00000048118	RatGTEx
SMART	ANK	UniProtKB/TrEMBL
Superfamily-SCOP	ANK	UniProtKB/TrEMBL
UniProt	A0ABK0L4D2_RAT	UniProtKB/TrEMBL
	A0ABK0LBF9_RAT	UniProtKB/TrEMBL
	A0ABZ3NN73_RAT	UniProtKB/TrEMBL
	A6I538	ENTREZGENE, UniProtKB/TrEMBL
	A6I539	ENTREZGENE, UniProtKB/TrEMBL
	M0R870	ENTREZGENE
	Q6Q287	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	M0R870	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Ankra2	ankyrin repeat family A member 2	LOC100910438	ankyrin repeat family A protein 2-like	Data merged from RGD:6498684	737654	PROVISIONAL
2016-01-13	Ankra2	ankyrin repeat family A member 2	Ankra2	ankyrin repeat, family A (RFXANK-like), 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-05	LOC100910438	ankyrin repeat family A protein 2-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-03-30	Ankra2	ankyrin repeat, family A (RFXANK-like), 2	LOC294679	SLO-interacting ankyrin-containing protein	Symbol and Name updated	1299863	APPROVED
2005-09-30	LOC294679				Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message