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Gene: Rnase6 (ribonuclease A family member 6) Rattus norvegicus

Analyze

Symbol:

Rnase6

Name:

ribonuclease A family member 6

RGD ID:

1303020

Description:

Predicted to enable RNA nuclease activity. Predicted to be involved in defense response to bacterium and defense response to symbiont. Predicted to be located in cytoplasmic vesicle. Predicted to be active in extracellular space. Orthologous to human RNASE6 (ribonuclease A family member 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC103694852; LOC305842; ribonuclease A family member k6; ribonuclease K6; ribonuclease K6-like; ribonuclease, RNase A family, 6; ribonuclease, RNase A family, k6; RNase 6

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	26,827,896 - 26,830,807 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	26,827,009 - 26,830,825 (+)	Ensembl				GRCr8
mRatBN7.2	15	24,354,305 - 24,357,289 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	24,354,303 - 24,357,328 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	27,127,289 - 27,127,750 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	28,086,431 - 28,086,892 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	26,335,850 - 26,336,311 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	28,080,307 - 28,084,269 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	28,081,004 - 28,081,465 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	31,888,498 - 31,906,605 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	27,117,646 - 27,118,107 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	24,673,730 - 24,674,191 (+)	NCBI		Celera
RGSC_v3.1	15	27,133,345 - 27,133,807 (+)	NCBI
Cytogenetic Map	15	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

liver disease (ISO)

toxic encephalopathy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2-butoxyethanol (ISO)

acetylsalicylic acid (ISO)

aflatoxin B1 (ISO)

amphetamine (EXP)

antirheumatic drug (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

buta-1,3-diene (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroprene (EXP,ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

diclofenac (EXP)

dimethylarsinic acid (ISO)

diquat (ISO)

disodium selenite (ISO)

diuron (ISO)

doxorubicin (ISO)

fragrance (ISO)

gentamycin (EXP)

inulin (ISO)

malathion (EXP)

methylarsonic acid (ISO)

nickel atom (ISO)

nickel sulfate (ISO)

nitrates (ISO)

nitrobenzenes (EXP)

paracetamol (EXP)

perfluorooctane-1-sulfonic acid (ISO)

pioglitazone (ISO)

pirinixic acid (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium dichromate (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

triphenyl phosphate (ISO)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antibacterial humoral response (IBA,ISO)

antimicrobial humoral immune response mediated by antimicrobial peptide (IBA,ISO)

biological_process (ND)

defense response to bacterium (IEA)

defense response to Gram-negative bacterium (IBA,ISO)

defense response to Gram-positive bacterium (IBA,ISO)

defense response to virus (ISO)

innate immune response (IBA,ISO)

Cellular Component

cytoplasmic vesicle (ISO)

extracellular region (IEA)

extracellular space (IBA,ISO)

lysosome (IEA)

Molecular Function

endonuclease activity (IEA)

hydrolase activity (IEA)

nuclease activity (IEA)

nucleic acid binding (IEA)

RNA nuclease activity (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:9826755	PMID:23376485	PMID:25075772

Genomics

Comparative Map Data

Rnase6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	26,827,896 - 26,830,807 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	26,827,009 - 26,830,825 (+)	Ensembl				GRCr8
mRatBN7.2	15	24,354,305 - 24,357,289 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	24,354,303 - 24,357,328 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	27,127,289 - 27,127,750 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	28,086,431 - 28,086,892 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	26,335,850 - 26,336,311 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	28,080,307 - 28,084,269 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	28,081,004 - 28,081,465 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	31,888,498 - 31,906,605 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	27,117,646 - 27,118,107 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	24,673,730 - 24,674,191 (+)	NCBI		Celera
RGSC_v3.1	15	27,133,345 - 27,133,807 (+)	NCBI
Cytogenetic Map	15	p14	NCBI

RNASE6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	20,781,070 - 20,782,467 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	20,781,068 - 20,782,467 (+)	Ensembl			hg38	GRCh38
GRCh37	14	21,249,427 - 21,250,626 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	20,319,050 - 20,320,466 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	14	20,319,049 - 20,320,464	NCBI
Celera	14	1,110,074 - 1,111,490 (+)	NCBI		Celera
Cytogenetic Map	14	q11.2	NCBI
HuRef	14	1,370,222 - 1,371,638 (+)	NCBI		HuRef
CHM1_1	14	21,251,198 - 21,252,614 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	14,978,092 - 14,979,588 (+)	NCBI		T2T-CHM13v2.0

Rnase6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	51,361,365 - 51,369,644 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	51,361,365 - 51,369,644 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	51,123,908 - 51,132,187 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	51,123,908 - 51,132,187 (+)	Ensembl			mm10	GRCm38
MGSCv37	14	51,748,743 - 51,750,797 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	14	50,051,041 - 50,052,975 (+)	NCBI		MGSCv36	mm8
Celera	14	47,424,272 - 47,426,326 (+)	NCBI		Celera
Cytogenetic Map	14	C1	NCBI
cM Map	14	26.39	NCBI

Rnase6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955550	1,687,068 - 1,688,160 (-)	NCBI	ChiLan1.0	ChiLan1.0

RNASE6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	22,278,035 - 22,279,920 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	21,494,353 - 21,496,407 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	1,642,819 - 1,644,582 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	19,699,881 - 19,701,303 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	19,700,536 - 19,700,988 (+)	Ensembl			panPan2	panpan1.1

LOC106559796
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	18,024,375 - 18,025,871 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	18,509,979 - 18,511,491 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	18,285,311 - 18,286,754 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	15	17,966,610 - 17,968,121 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	18,022,678 - 18,024,183 (+)	NCBI		UNSW_CanFamBas_1.0

Rnase6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	32,168,616 - 32,169,962 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936880	78,081 - 79,021 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936880	78,532 - 79,342 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RNASE6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	78,220,131 - 78,221,665 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	78,220,131 - 78,221,665 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

RNASE6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	21,285,708 - 21,287,452 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	29	21,286,685 - 21,287,134 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666059	25,143,712 - 25,145,458 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rnase6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624825	4,468,213 - 4,469,566 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624825	4,468,213 - 4,469,557 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Rnase6
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	12	72,147,213 - 72,149,790 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Rnase6
37 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	305
Count of miRNA genes:	181
Interacting mature miRNAs:	207
Transcripts:	ENSRNOT00000033739
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1641913	Colcr2	Colorectal carcinoma resistance QTL 2	6.57	0.0197	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	15	2315759	47315759	Rat
5684946	Bss98	Bone structure and strength QTL 98	3.9	0.0026	tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	15	1	39411584	Rat
1641887	Alcrsp14	Alcohol response QTL 14			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	15	1	44836456	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2315759	53331089	Rat
10755503	Bp391	Blood pressure QTL 391	2.37		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	22728353	42072050	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	25285835	104695021	Rat
2324620	Coatc3	Coat color QTL 3			coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	15	22336351	52597086	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	25285835	104695021	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	19155762	87086765	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	2785923	47785923	Rat
1354657	Despr13	Despair related QTL 13		0.0022	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	15	1	32342855	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	14926594	71614418	Rat
631550	Bw7	Body weight QTL 7	3.6		body mass (VT:0001259)	body weight (CMO:0000012)	15	22336351	67336351	Rat
5685002	Bss103	Bone structure and strength QTL 103	2.8		tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	15	16911521	32439851	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	25285835	104695021	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
11	1	21	65	44	40	28	74	28	6	201	117	11	47	45	48	12	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_206815	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251871	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251872	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770520	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008773787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008773788	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599665	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599666	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC114343	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY545654	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474040	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000033739 ⟹ ENSRNOP00000031392

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	26,827,009 - 26,830,825 (+)	Ensembl
mRatBN7.2 Ensembl	15	24,354,303 - 24,357,328 (+)	Ensembl
Rnor_6.0 Ensembl	15	28,081,004 - 28,081,465 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000151768 ⟹ ENSRNOP00000100358

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	26,827,009 - 26,830,825 (+)	Ensembl

RefSeq Acc Id:

NM_206815 ⟹ NP_996538

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	26,829,645 - 26,830,106 (+)	NCBI
mRatBN7.2	15	24,356,131 - 24,356,592 (+)	NCBI
Rnor_6.0	15	28,081,004 - 28,081,465 (-)	NCBI
Rnor_5.0	15	31,888,498 - 31,906,605 (+)	NCBI
RGSC_v3.4	15	27,117,646 - 27,118,107 (+)	RGD
Celera	15	24,673,730 - 24,674,191 (+)	RGD

Sequence:

show sequence

ATGGCGGTAGACCTTCCCAGGTGGCTTCCTCTCCTATTACTGCTGGGGCTGTGGGAGCCCATGG
GTCTGCTTTGTGCTCAGCCTAAGGGTCTCTCCAAGGCGCGCTGGTTTGAAATTCAGCACATATG
GGCTAGTCCTCAGCAGTGCAATGCAGCCATGCGTGGTGTCAACAACTATACCCGATACTGTAAG
CAGAAGAACACCTTTCTGCATGAATCTTTCCAGAATGTGGCTGCTACCTGCGGTTTGCCCAACA
TCACATGCAAGAACGGTCGGAAGAACTGCCACGAGAGTGTGAAGCCTGTCAAAATGACTGACTG
CTCACACACAGGGCAAGCCTATCCTAACTGCCGCTACAGTGGTGATGTCCAATACAAACTCTTC
GTTGTGGCCTGTGAACACCCAAAGAAGGACGACCCTCCCTACCAACTGGTTCCTGTGCACTTAG
ATAAGGTTGTGTAA

hide sequence

RefSeq Acc Id:

XM_008773787 ⟹ XP_008772009

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	26,827,976 - 26,830,807 (+)	NCBI
mRatBN7.2	15	24,354,305 - 24,357,289 (+)	NCBI

Sequence:

show sequence

AATCACAGGGCTTCAAAAACGGAAGCTCCAGTCAAACACGAAGTGCTAAGCCCACAGAAAGCGG
TCAGGCACTTAAAACTCTGAGTGTTGAGCCTACTGGTTTCTTGAGTTCAGTTTATTCTCCCTTT
TCACTGACATGGAAACGTTTAAAGAGCTTCCTTGGAGGTGGAGAGTCTTAGCCCACTACACTTC
TGCAAAATCTTCTCTGGTTTCTCTTTCATGGTTTAAGAATAAATCTTGCCCTGCCCCACCTAGG
CAGCTGTGACTGCCCTGAAGAAGTGAGGCCAACAAAGCATTCTGAGCCTGGGACTCATCAACTG
CCCCTGTCACAGTAGGAGCCCAGCAGGAACACCTGGTAAGAGAGGTCCTTCAGGGCCCTGCCAG
GCAGTGGGGTTGGCTGGGAAATGCTGGCTGGAGACGGAAGGCAAAAAACCATGGCGGTAGACCT
TCCCAGGTGGCTTCCTCTCCTATTACTGCTGGGGCTGTGGGAGCCCATGGGTCTGCTTTGTGCT
CAGCCTAAGGGTCTCTCCAAGGCGCGCTGGTTTGAAATTCAGCACATATGGGCTAGTCCTCAGC
AGTGCAATGCAGCCATGCGTGGTGTCAACAACTATACCCGATACTGTAAGCAGAAGAACACCTT
TCTGCATGAATCTTTCCAGAATGTGGCTGCTACCTGCGGTTTGCCCAACATCACATGCAAGAAC
GGTCGGAAGAACTGCCACGAGAGTGTGAAGCCTGTCAAAATGACTGACTGCTCACACACAGGGC
AAGCCTATCCTAACTGCCGCTACAGTGGTGATGTCCAATACAAACTCTTCGTTGTGGCCTGTGA
ACACCCAAAGAAGGACGACCCTCCCTACCAACTGGTTCCTGTGCACTTAGATAAGGTTGTGTAA
GGCTTAGGGTCTTCCCAGGTGTTCAGCACAGGCTGCCTTGCAATTTATCCCTTGTTGCCTTTTG
TTCCCACAGAAAAGGAAAGGTGTTGGAAAGATTAAGATGCCTAAGCTATCCAAATGGAGGGTTT
TCTTGTTTTTTGTTTTGTTTTGTTTTGTTTTTTTTAAAAAGGGAGTGCATGAGTTACTTACTTA
GTGTACAGAGGTCCCTAGGTTCAATCACCACCCCACCACCACCACCAATAAATAAATAAATAAA
TAAATAAATAAATAAATAAATAGAGAAAGGAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGGAA
GGAAGGAAGAAGAAAGAGGGTTACCTTTGTTGAAGGAGGAATATAAGAAAAGCATAACGAAGGT
CCAAGCTTCTGAACACTTTATCCTGCATTTTTTTGCATCAAGCTTTATTGTACTATGCTCATAG
AATTTAAAAAAATCTTCTTTTTTAATATAACGAGTGTGAATTTGCCGGGTTATTTGTTGTGTGT
GTTTTGACAGAGAGCCCTGGCTGCTCCTCAAGAAGACCTAGGTTTGATTCCCAGCTCCCACAAC
CACCGGGAACTCTAGCTCTGCCAACCTTTTCTGGCCTCCAAGAGTACCACACATTTCCATGGCT
CACAGACATACATGCAGGCCAAGCACCATGCACATAAAATAAAGTTCAAAAATATTA

hide sequence

RefSeq Acc Id:

XM_008773788 ⟹ XP_008772010

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	26,827,896 - 26,830,807 (+)	NCBI
mRatBN7.2	15	24,354,313 - 24,357,289 (+)	NCBI

Sequence:

show sequence

ATCACAGGGCTTCAAAAACGGAAGCTCCAGTCAAACACGAAGTGCTAAGCCCACAGAAAGCGGT
CAGGCACTTAAAACTCTGAGTGTTGAGCCTACTGGTTTCTTGAGTTCAGTTTATTCTCCCTTTT
CACTGACATGGAAACGTTTAAAGAGCTTCCTTGGAGGTGGAGAGTCTTAGCCCACTACACTTCT
GCAAAATCTTCTCTGGTTTCTCTTTCATGGTTTAAGAATAAATCTTGCCCTGCCCCACCTAGGC
AGCTGTGACTGCCCTGAAGAAGTGAGGCCAACAAAGCATTCTGAGCCTGGGACTCATCAACTGC
CCCTGTCACAGTAGGAGCCCAGCAGGAACACCTGGCAAAAAACCATGGCGGTAGACCTTCCCAG
GTGGCTTCCTCTCCTATTACTGCTGGGGCTGTGGGAGCCCATGGGTCTGCTTTGTGCTCAGCCT
AAGGGTCTCTCCAAGGCGCGCTGGTTTGAAATTCAGCACATATGGGCTAGTCCTCAGCAGTGCA
ATGCAGCCATGCGTGGTGTCAACAACTATACCCGATACTGTAAGCAGAAGAACACCTTTCTGCA
TGAATCTTTCCAGAATGTGGCTGCTACCTGCGGTTTGCCCAACATCACATGCAAGAACGGTCGG
AAGAACTGCCACGAGAGTGTGAAGCCTGTCAAAATGACTGACTGCTCACACACAGGGCAAGCCT
ATCCTAACTGCCGCTACAGTGGTGATGTCCAATACAAACTCTTCGTTGTGGCCTGTGAACACCC
AAAGAAGGACGACCCTCCCTACCAACTGGTTCCTGTGCACTTAGATAAGGTTGTGTAAGGCTTA
GGGTCTTCCCAGGTGTTCAGCACAGGCTGCCTTGCAATTTATCCCTTGTTGCCTTTTGTTCCCA
CAGAAAAGGAAAGGTGTTGGAAAGATTAAGATGCCTAAGCTATCCAAATGGAGGGTTTTCTTGT
TTTTTGTTTTGTTTTGTTTTGTTTTTTTTAAAAAGGGAGTGCATGAGTTACTTACTTAGTGTAC
AGAGGTCCCTAGGTTCAATCACCACCCCACCACCACCACCAATAAATAAATAAATAAATAAATA
AATAAATAAATAAATAGAGAAAGGAAGAAAGAAAGAAAGAAAGAAAGAAAGAAAGGAAGGAAGG
AAGAAGAAAGAGGGTTACCTTTGTTGAAGGAGGAATATAAGAAAAGCATAACGAAGGTCCAAGC
TTCTGAACACTTTATCCTGCATTTTTTTGCATCAAGCTTTATTGTACTATGCTCATAGAATTTA
AAAAAATCTTCTTTTTTAATATAACGAGTGTGAATTTGCCGGGTTATTTGTTGTGTGTGTTTTG
ACAGAGAGCCCTGGCTGCTCCTCAAGAAGACCTAGGTTTGATTCCCAGCTCCCACAACCACCGG
GAACTCTAGCTCTGCCAACCTTTTCTGGCCTCCAAGAGTACCACACATTTCCATGGCTCACAGA
CATACATGCAGGCCAAGCACCATGCACATAAAATAAAGTTCAAAAATATTA

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Protein Sequences


Protein RefSeqs	NP_996538	(Get FASTA)	NCBI Sequence Viewer
	XP_008772009	(Get FASTA)	NCBI Sequence Viewer
	XP_008772010	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAS48639	(Get FASTA)	NCBI Sequence Viewer
	EDL88442	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000031392
	ENSRNOP00000031392.1
	ENSRNOP00000100358.1

RefSeq Acc Id:	NP_996538 ⟸ NM_206815
- Peptide Label:	precursor
- UniProtKB:	Q6QDX6 (UniProtKB/TrEMBL), F7ETH7 (UniProtKB/TrEMBL), W0UTF7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVDLPRWLPLLLLLGLWEPMGLLCAQPKGLSKARWFEIQHIWASPQQCNAAMRGVNNYTRYCK QKNTFLHESFQNVAATCGLPNITCKNGRKNCHESVKPVKMTDCSHTGQAYPNCRYSGDVQYKLF VVACEHPKKDDPPYQLVPVHLDKVV hide sequence

Ensembl Acc Id:

ENSRNOP00000031392 ⟸ ENSRNOT00000033739

RefSeq Acc Id:	XP_008772009 ⟸ XM_008773787
- Peptide Label:	isoform X1
- UniProtKB:	W0UTF7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLAGDGRQKTMAVDLPRWLPLLLLLGLWEPMGLLCAQPKGLSKARWFEIQHIWASPQQCNAAMR GVNNYTRYCKQKNTFLHESFQNVAATCGLPNITCKNGRKNCHESVKPVKMTDCSHTGQAYPNCR YSGDVQYKLFVVACEHPKKDDPPYQLVPVHLDKVV hide sequence

RefSeq Acc Id:	XP_008772010 ⟸ XM_008773788
- Peptide Label:	isoform X2
- UniProtKB:	Q6QDX6 (UniProtKB/TrEMBL), F7ETH7 (UniProtKB/TrEMBL), W0UTF7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVDLPRWLPLLLLLGLWEPMGLLCAQPKGLSKARWFEIQHIWASPQQCNAAMRGVNNYTRYCK QKNTFLHESFQNVAATCGLPNITCKNGRKNCHESVKPVKMTDCSHTGQAYPNCRYSGDVQYKLF VVACEHPKKDDPPYQLVPVHLDKVV hide sequence

Ensembl Acc Id:

ENSRNOP00000100358 ⟸ ENSRNOT00000151768

Protein Domains

Ribonuclease A-domain

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6QDX6-F1-model_v2	AlphaFold	Q6QDX6	1-153	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303020	AgrOrtholog
BioCyc Gene	G2FUF-14026	BioCyc
Ensembl Genes	ENSRNOG00000025597	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000033739	ENTREZGENE
	ENSRNOT00000033739.5	UniProtKB/TrEMBL
	ENSRNOT00000151768.1	UniProtKB/TrEMBL
Gene3D-CATH	3.10.130.10	UniProtKB/TrEMBL
InterPro	RNaseA	UniProtKB/TrEMBL
	RNaseA-like_dom_sf	UniProtKB/TrEMBL
	RNaseA_AS	UniProtKB/TrEMBL
	RNaseA_domain	UniProtKB/TrEMBL
KEGG Report	rno:305842	UniProtKB/TrEMBL
NCBI Gene	305842	ENTREZGENE
PANTHER	RIBONUCLEASE K6	UniProtKB/TrEMBL
	RNaseA	UniProtKB/TrEMBL
Pfam	RnaseA	UniProtKB/TrEMBL
PharmGKB	RNASE6	RGD
PhenoGen	Rnase6	PhenoGen
PRINTS	RIBONUCLEASE	UniProtKB/TrEMBL
PROSITE	RNASE_PANCREATIC	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000025597	RatGTEx
SMART	RNAse_Pc	UniProtKB/TrEMBL
Superfamily-SCOP	RNaseA	UniProtKB/TrEMBL
UniProt	A0ABK0KZ55_RAT	UniProtKB/TrEMBL
	F7ETH7	ENTREZGENE, UniProtKB/TrEMBL
	Q6QDX6	ENTREZGENE, UniProtKB/TrEMBL
	W0UTF7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2024-07-19	Rnase6	ribonuclease A family member 6	Rnase6	ribonuclease A family member k6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2021-03-09	Rnase6	ribonuclease A family member k6	LOC103694852	ribonuclease K6-like	Data merged from RGD:9070017	737654	PROVISIONAL
2018-04-04	Rnase6	ribonuclease A family member k6	Rnase6	ribonuclease, RNase A family, 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-08-25	LOC103694852	ribonuclease K6-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-03-19	Rnase6	ribonuclease, RNase A family, 6	Rnase6	ribonuclease, RNase A family, k6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Rnase6	ribonuclease, RNase A family, k6	Rnase6	ribonuclease, RNase A family, 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-28		ribonuclease, RNase A family, 6	Rnase6	ribonuclease, RNase A family, k6	status set to approved	1299863	APPROVED
2005-01-11	Rnase6	ribonuclease, RNase A family, k6	LOC305842	RNase 6	Symbol and Name updated to reflect Human and Mouse nomenclature	1299863	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD