| 3889 | Tp53 | tumor protein p53 | ENCODES a protein that exhibits MDM2/MDM4 family protein binding; RNA polymerase II-specific DNA-binding transcription factor binding; sequence-specific DNA binding; INVOLVED IN apoptotic signaling pathway; cellular response to heat; cellular response to hypoxia; PARTICIPATES IN altered p53 signalin g pathway; endometrial cancer pathway; non-small cell lung carcinoma pathway; ASSOCIATED WITH abnormal vacuole morphology; decreased body weight; decreased testis weight; ASSOCIATED WITH bronchiolo-alveolar adenocarcinoma; bronchopulmonary dysplasia; colorectal cancer; FOUND IN chromatin; nucleus; PML body; INTERACTS WITH (+)-catechin; (+)-dexrazoxane; (+)-schisandrin B | 10 | 54798871 | 54810300 | Rat | 4013 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 1586180 | Tp53-ps1 | tumor protein p53, pseudogene 1 | | 9 | 31306990 | 31308521 | Rat | | symbol , PhenoGen | gene, pseudo, INFERRED [RefSeq] |
| 1583884 | Tp53-ps2 | tumor protein p53, pseudogene 2 | | 2 | 202085069 | 202086044 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 2293297 | Tp53-ps3 | tumor protein p53, pseudogene 3 | | 18 | 83231834 | 83233514 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 12792955 | Tp53m1Kyo | tumor protein p53; ENU induced mutant1, Kyo, | A missense mutation R271C in the rat Tp53 was induced by ethylnitrosourea (ENU) mutagenesis in F344/Nslc. | | | | Rat | | symbol , old_gene_name , description , old_gene_symbol | gene, allele |
| 12904898 | Tp53em1Sage | tumor protein p53; ZFN induced mutant 1, Sage | ASSOCIATED WITH abnormal vacuole morphology; decreased body weight; decreased testis weight; ASSOCIATED WITH Hypogonadism and Testicular Atrophy | | | | Rat | 9 | symbol , description , old_gene_symbol | gene, allele |
| 11553885 | Tp53em3Mcwi | tumor protein p53;zinc finger nuclease induced mutant 3, Medical College of Wisconsin | This allele was made by ZFN system. The resulting mutation is a 84-bp deletion in Exon 3 of the Tp53 gene. | | | | Rat | | symbol , description , old_gene_symbol | gene, allele |
| 12792957 | Tp53tm1(EGFP-Pac)Qly | tumor protein p53; tm1, EGFP-Pac, Qly | This allele was made by electroporation of DAc8 embryonic stem cells with a targeting vector containing 6.7kb 5' and 1.6- kb 3' homology arms and a CAG-EGFP-IRES-Pac cassette. Absence of Tp53 protein was confirmed by western blot in homozygous animals. | | | | Rat | | symbol , description , old_gene_symbol | gene, allele |
| 1561934 | Tp53tg5 | TP53 target 5 | FOUND IN chromosome (ortholog); nucleolus (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; bisphenol A; aflatoxin B1 (ortholog) | 3 | 173620152 | 173623673 | Rat | 13 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1586233 | Triap1 | TP53 regulated inhibitor of apoptosis 1 | ENCODES a protein that exhibits p53 binding (ortholog); phosphatidic acid transfer activity (ortholog); INVOLVED IN cellular response to UV (ortholog); DNA damage response, signal transduction by p53 class mediator (ortholog); mitotic G1 DNA damage checkpoint signaling (ortholog); FOUND IN mitochond rial intermembrane space (ortholog); mitochondrion (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; bisphenol A | 12 | 46928273 | 46930766 | Rat | 107 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1359624 | Wrap53 | WD repeat containing, antisense to TP53 | ENCODES a protein that exhibits histone binding (ortholog); identical protein binding (ortholog); protein carrier chaperone (ortholog); INVOLVED IN Cajal body organization (ortholog); positive regulation of DNA repair (ortholog); positive regulation of double-strand break repair (ortholog); ASSOCIAT ED WITH Autosomal Recessive Dyskeratosis Congenita (ortholog); autosomal recessive dyskeratosis congenita 3 (ortholog); Body Weight (ortholog); FOUND IN glutamatergic synapse; postsynaptic density membrane; Cajal body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 54780873 | 54797919 | Rat | 164 | old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1591394 | Tp53rka | Tp53 tumor protein p53 regulating kinase A | ENCODES a protein that exhibits p53 binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN protein phosphorylation (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); Galloway-Mowat syndrome (ortholog); Galloway-Mowat syndrome 4 (ortholog); FOUND IN cytop lasm (ortholog); EKC/KEOPS complex (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; bisphenol A; dibutyl phthalate | 3 | 174638962 | 174645198 | Rat | 76 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1560038 | Tigar | TP53 induced glycolysis regulatory phosphatase | ENCODES a protein that exhibits fructose-2,6-bisphosphate 2-phosphatase activity (ortholog); INVOLVED IN cellular response to cobalt ion (ortholog); cellular response to hypoxia (ortholog); DNA damage response (ortholog); ASSOCIATED WITH Nerve Degeneration (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial outer membrane (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acetamide | 4 | 161613306 | 161632248 | Rat | 172 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1595512 | Rprm | reprimo, TP53 dependent G2 arrest mediator homolog | INVOLVED IN regulation of cell cycle (ortholog); regulation of mitotic cell cycle (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Barrett's esophagus (ortholog); Esophageal Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-ace tamidofluorene; 3,3',5,5'-tetrabromobisphenol A | 3 | 58948618 | 58950035 | Rat | 109 | old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308005 | Tigar-ps1 | TP53 induced glycolysis regulatory phosphatase, pseudogene 1 | INTERACTS WITH bisphenol A | 6 | 93245595 | 93247965 | Rat | 1 | name | gene, pseudo, INFERRED [RefSeq] |
| 1306045 | Rrm2b | ribonucleotide reductase regulatory TP53 inducible subunit M2B | ENCODES a protein that exhibits identical protein binding (ortholog); ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (ortholog); INVOLVED IN response to amine; 2'-deoxyribonucleotide biosynthetic process (ortholog); deoxyribonucleoside triphosphate metabolic process (ortholog); PARTICIPATES IN beta-ureidopropionase deficiency pathway; dihydropyrimidinase deficiency pathway; gemcitabine pharmacodynamics pathway; ASSOCIATED WITH autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 5 (ortholog); Camptocormia (ortholog); chronic progressive external ophthalmoplegia (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; aflatoxin B1 | 7 | 70962008 | 70993726 | Rat | 223 | old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308039 | Tp53bp1 | tumor protein p53 binding protein 1 | ENCODES a protein that exhibits histone H4K20me methyltransferase activity (ortholog); histone H4K20me2 reader activity (ortholog); histone reader activity (ortholog); INVOLVED IN cellular response to X-ray; DNA damage response (ortholog); double-strand break repair via classical nonhomologous end j oining (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; non-homologous end joining pathway of double-strand break repair; ASSOCIATED WITH Breast Neoplasms (ortholog); Colonic Neoplasms (ortholog); glioblastoma (ortholog); FOUND IN chromosome, telomeric region (ortholog); cytoplasm (ortholog); nuclear body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid; atrazine | 3 | 128620320 | 128724716 | Rat | 242 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1304911 | Tp53rkb | tumor protein p53 regulating kinase B | ENCODES a protein that exhibits ATP binding (inferred); catalytic activity (inferred); hydrolase activity (inferred); INVOLVED IN tRNA processing (inferred); FOUND IN EKC/KEOPS complex (inferred); nucleus (inferred); INTERACTS WITH 1,2-dimethylhydrazine (ortholog); 4,4'-sulfonyldiphenol (ortholog); bisphenol A (ortholog) | 3 | 175948060 | 175951732 | Rat | 31 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1310294 | Perp | p53 apoptosis effector related to PMP22 | INVOLVED IN amelogenesis (ortholog); desmosome organization (ortholog); heterotypic cell-cell adhesion (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Erythrokeratodermia Variabilis et Progressiva 7 (ortholog); genetic disease (ortholog); Olmsted Syndrome 2 (ortholog); FOUND IN cy toplasm (ortholog); desmosome (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 15361784 | 15374230 | Rat | 170 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 41235940 | Tp53i3 | tumor protein p53 inducible protein 3 | ENCODES a pseudogene that exhibits quinone reductase (NADPH) activity (ortholog); INVOLVED IN apoptotic process (ortholog); reactive oxygen species biosynthetic process (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); autism spectrum disorder (ortholog); carcinoma (ortholog); INTERAC TS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 6 | 33537779 | 33545204 | Rat | 130 | symbol , PhenoGen | gene, pseudo, INFERRED [RefSeq] |
| 1305461 | Tp53bp2 | tumor protein p53 binding protein, 2 | ENCODES a protein that exhibits identical protein binding (ortholog); NF-kappaB binding (ortholog); p53 binding (ortholog); INVOLVED IN positive regulation of cellular process; intrinsic apoptotic signaling pathway by p53 class mediator (ortholog); positive regulation of execution phase of apoptosis (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH breast lobular carcinoma (ortholog); Breast Neoplasms (ortholog); chromosome 1q41-q42 deletion syndrome (ortholog); FOUND IN cell junction (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 13 | 96620429 | 96677090 | Rat | 133 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1308395 | Tp53i11 | tumor protein p53 inducible protein 11 | FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide | 3 | 99600213 | 99615462 | Rat | 122 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1559818 | Tp53i13 | tumor protein p53 inducible protein 13 | INVOLVED IN negative regulation of cell cycle (ortholog); response to UV (ortholog); response to xenobiotic stimulus (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid | 10 | 62854851 | 62861241 | Rat | 59 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 631423 | Tp53inp1 | tumor protein p53 inducible nuclear protein 1 | ENCODES a protein that exhibits antioxidant activity (ortholog); INVOLVED IN autophagic cell death (ortholog); cellular response to ethanol (ortholog); cellular response to hydroperoxide (ortholog); ASSOCIATED WITH abdominal obesity-metabolic syndrome 1 (ortholog); FOUND IN autophagosome (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 5 | 29051267 | 29069486 | Rat | 270 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 735085 | Tp53inp2 | tumor protein p53 inducible nuclear protein 2 | INVOLVED IN autophagosome assembly (ortholog); positive regulation of DNA-templated transcription (ortholog); FOUND IN autophagosome (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 17beta-estradiol | 3 | 164341618 | 164350270 | Rat | 177 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304982 | Cryzl2 | crystallin zeta like 2 | ENCODES a protein that exhibits oxidoreductase activity (inferred); INTERACTS WITH (1->4)-beta-D-glucan (ortholog); 17beta-estradiol (ortholog); aristolochic acid A (ortholog) | 13 | 72146147 | 72210258 | Rat | 18 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1309786 | Tprkb | Tp53rk binding protein | ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN tRNA threonylcarbamoyladenosine modification (ortholog); ASSOCIATED WITH Galloway-Mowat syndrome (ortholog); Galloway-Mowat syndrome 5 (ortholog); nephrotic syndrome (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ort holog); EKC/KEOPS complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cobalt dichloride | 4 | 119900374 | 119915374 | Rat | 91 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |