| 1308374 | Sirt3 | sirtuin 3 | ENCODES a protein that exhibits enzyme binding; histone H3K14 deacetylase activity, NAD-dependent (ortholog); NAD-dependent protein lysine deacetylase activity (ortholog); INVOLVED IN negative regulation of ERK1 and ERK2 cascade; negative regulation of reactive oxygen species metabolic process; posi tive regulation of insulin secretion; PARTICIPATES IN histone modification pathway; Sirtuin mediated pathway; ASSOCIATED WITH congestive heart failure; metabolic dysfunction-associated steatotic liver disease; myocardial infarction; FOUND IN cytoplasm (ortholog); membrane (ortholog); mitochondrial inner membrane (ortholog); INTERACTS WITH (+)-schisandrin B; (R)-lipoic acid; 1,3,7,9-tetramethyluric acid | 1 | 205371703 | 205394145 | Rat | 334 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 10054451 | Sirt3em4Mcwi | sirtuin 3; CRISPR/Cas9 system induced mutant 4, Medical College of Wisconsin | This allele was made by CRISPR/Cas9 system. The resulting mutation is a 7-bp deletion in the Sirt3 gene | | | | Rat | | symbol , description , old_gene_symbol | gene, allele |
| 10054448 | Sirt3em25Mcwi | sirtuin 3; CRISPR/Cas9 system induced mutant 25, Medical College of Wisconsin | This allele was made by CRISPR/Cas9 system. The resulting mutation is a 13-bp deletion in the Sirt3 gene;(RGSC 5.0/rn5) deleted region: chr1:220,552,421-220,552,433 | | | | Rat | | symbol , description , old_gene_symbol | gene, allele |
| 10054457 | Sirt3em30Mcwi | sirtuin 3; CRISPR/Cas9 system induced mutant 30, Medical College of Wisconsin | This allele was made by CRISPR/Cas9 system. The resulting mutation is a 31-bp deletion of exon 3 in the Sirt3 gene | | | | Rat | | symbol , description , old_gene_symbol | gene, allele |
| 10054454 | Sirt3em35Mcwi | sirtuin 3; CRISPR/Cas9 system induced mutant 35, Medical College of Wisconsin | This allele was made by CRISPR/Cas9 system. The resulting mutation is a 82-bp deletion of exon 3 in the Sirt3 gene | | | | Rat | | symbol , description , old_gene_symbol | gene, allele |