| 1586165 | Kmt2a | lysine methyltransferase 2A | ENCODES a protein that exhibits DNA-binding transcription factor binding; chromatin binding (ortholog); DNA binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus; membrane depolarization; positive regulation of gene expression; PARTICIPATES IN DNA modification pathway; histone modification pathway; ASSOCIATED WITH transient cerebral ischemia; Acute Erythroleukemia (ortholog); acute lymphoblastic leukemia (ortholog); FOUND IN histone methyltransferase complex (ortholog); MLL1 complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene | 8 | 54013547 | 54089219 | Rat | 298 | description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1305632 | Ash2l | ASH2 like histone lysine methyltransferase complex subunit | ENCODES a protein that exhibits beta-catenin binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN DNA damage response (ortholog); positive regulation of cell population proliferation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH schizophrenia; Developmental Disabilities (ortholog); FOUND IN euchromatin (ortholog); histone methyltransferase complex (ortholog); MLL1 complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 16 | 72943527 | 72966791 | Rat | 96 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308134 | Bacc1 | BPTF associated chromatin complex component 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN chromatin organization (inferred); FOUND IN MLL1 complex (ortholog); NURF complex (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 55450648 | 55453409 | Rat | 49 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620696 | Chd8 | chromodomain helicase DNA binding protein 8 | ENCODES a protein that exhibits armadillo repeat domain binding; beta-catenin binding; ATP binding (ortholog); INVOLVED IN negative regulation of canonical Wnt signaling pathway; negative regulation of DNA-templated transcription; negative regulation of Wnt signaling pathway; PARTICIPATES IN Wnt sig naling pathway; ASSOCIATED WITH anxiety disorder (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN nucleus; protein-containing complex; MLL1 complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 15 | 27379285 | 27438959 | Rat | 225 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 631412 | E2f6 | E2F transcription factor 6 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); regulation of transcrip tion by RNA polymerase II (ortholog); ASSOCIATED WITH lung non-small cell carcinoma (ortholog); primary ciliary dyskinesia 40 (ortholog); Triple Negative Breast Neoplasms (ortholog); FOUND IN MLL1 complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',5,5'-tetrabromobisphenol A | 6 | 45320993 | 45337437 | Rat | 113 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310199 | Ino80c | INO80 complex subunit C | INVOLVED IN chromatin remodeling (ortholog); positive regulation of DNA repair (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; FOUND IN fibrillar center (ortholog); Ino80 complex (ortholog); MLL1 ont-weight:700;'>MLL1 complex (ortholog); INTERACTS WITH bisphenol A; caffeine; flutamide | 18 | 15653508 | 15752455 | Rat | 96 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311429 | Kansl1 | KAT8 regulatory NSL complex subunit 1 | INVOLVED IN regulation of mitochondrial transcription (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Chromosome 17 Deletion (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN histone acetyltransferase complex (ortholog); mitochondrion (ortholog); MLL1 00;'>MLL1 complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; aflatoxin B1; amitrole | 10 | 89737637 | 89868620 | Rat | 91 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1565755 | Las1l | LAS1-like, ribosome biogenesis factor | ENCODES a protein that exhibits endonuclease activity (inferred); INVOLVED IN rRNA processing (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN MLL1 complex (ortholog); nu cleolus (ortholog); nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; acrylamide | X | 64861472 | 64883221 | Rat | 79 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561597 | Mga | MAX dimerization protein MGA | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH adenoid cystic carcinoma (ortholog); B-lymphoblastic leukemia/lymphoma (ortholog); multiple myeloma (ortholog); FOUND IN MLL1 complex (ortholog); transcription regulator complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 3 | 127300558 | 127396694 | Rat | 112 | description | gene, protein-coding, MODEL [RefSeq] |
| 1306320 | Pelp1 | proline, glutamate and leucine rich protein 1 | ENCODES a protein that exhibits chromatin binding (ortholog); SUMO binding (ortholog); INVOLVED IN cellular response to estrogen stimulus (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); FOUND IN euchromatin (ort holog); MLL1 complex (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 10 | 55593444 | 55610478 | Rat | 97 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305020 | Phf20 | PHD finger protein 20 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN chromatin organization (inferred); DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); ASSOCIATED WITH Dwarfism (ortholog); FOUND I N histone acetyltransferase complex (ortholog); MLL1 complex (ortholog); nuclear membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; acrylamide | 3 | 165170337 | 165279276 | Rat | 72 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305832 | Prpf31 | pre-mRNA processing factor 31 | ENCODES a protein that exhibits identical protein binding (ortholog); protein-macromolecule adaptor activity (ortholog); ribonucleoprotein complex binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); ribonucleoprotein complex localization (ortholog); snoRNA localization (orthol og); PARTICIPATES IN retinitis pigmentosa pathway; spliceosome pathway; ASSOCIATED WITH fundus dystrophy (ortholog); genetic disease (ortholog); Leber congenital amaurosis (ortholog); FOUND IN Cajal body (ortholog); MLL1 complex (ortholog); nuclear speck (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 4,4'-sulfonyldiphenol; aconitine | 1 | 74491247 | 74502922 | Rat | 121 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305532 | Rbbp5 | RB binding protein 5, histone lysine methyltransferase complex subunit | ENCODES a protein that exhibits histone binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN DNA damage response (ortholog); gene expression (ortholog); response to estrogen (ortholog); PARTICIPATES IN histone modification pathway; FOUND IN histone methyltransferas e complex (ortholog); MLL1 complex (ortholog); MLL3/4 complex (ortholog); INTERACTS WITH (+)-schisandrin B; bisphenol A; flutamide | 13 | 46464389 | 46494244 | Rat | 92 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1312040 | Senp3 | SUMO specific peptidase 3 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); cysteine-type peptidase activity (ortholog); deSUMOylase activity (ortholog); INVOLVED IN negative regulation of double-strand break repair via homologous recombination (ortholog); protein desumoylation (ortholog); FOU ND IN MLL1 complex (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 10 | 54889445 | 54898359 | Rat | 91 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1562050 | Taf1 | TATA-box binding protein associated factor 1 | ENCODES a protein that exhibits acetyl-CoA binding (ortholog); DNA binding (ortholog); histone acetyltransferase activity (ortholog); INVOLVED IN response to xenobiotic stimulus; cellular response to ATP (ortholog); cellular response to UV (ortholog); PARTICIPATES IN histone modification pathway; RN A polymerase II transcription initiation pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); congenital heart disease (ortholog); genetic disease (ortholog); FOUND IN chromatin (ortholog); MLL1 complex (ortholog); nucleolus (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,4-dinitrotoluene; 2,6-dinitrotoluene | X | 70680901 | 70756535 | Rat | 168 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1588072 | Taf4 | TATA-box binding protein associated factor 4 | ENCODES a protein that exhibits aryl hydrocarbon receptor binding (ortholog); core promoter sequence-specific DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN DNA-templated transcription (ortholog); DNA-templated transcription initiation (ortholog); mRNA transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autosomal dominant intellectual developmental disorder 73 (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN chromatin (ortholog); MLL1 complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH bisphenol A; vinclozolin; 1,2-dimethylhydrazine (ortholog) | 3 | 187395632 | 187461042 | Rat | 109 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1311608 | Taf6 | TATA-box binding protein associated factor 6 | ENCODES a protein that exhibits aryl hydrocarbon receptor binding (ortholog); DNA binding (ortholog); RNA polymerase II general transcription initiation factor activity (ortholog); INVOLVED IN DNA-templated transcription initiation (ortholog); mRNA transcription by RNA polymerase II (ortholog); nega tive regulation of cell cycle (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH Alazami-Yuan Syndrome (ortholog); Cornelia de Lange syndrome 1 (ortholog); Developmental Disabilities (ortholog); FOUND IN MLL1 complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 12 | 22169570 | 22178031 | Rat | 122 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309935 | Taf7 | TATA-box binding protein associated factor 7 | ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); histone acetyltransferase binding (ortholog); histone H3K27me3 reader activity (ortholog); INVOLVED IN DNA-templated transcription initiation (ortholog); estrogen receptor signaling pathway (ortholog); mRNA transcri ption by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; FOUND IN cytoplasm (ortholog); MLL1 complex (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 18 | 29704182 | 29713382 | Rat | 137 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 727861 | Taf9 | TATA-box binding protein associated factor 9 | ENCODES a protein that exhibits ATPase binding (ortholog); C2H2 zinc finger domain binding (ortholog); DNA binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II; response to L-glutamate; box C/D snoRNP assembly (ortholog); PARTICIPATES IN de novo purine biosynthet ic pathway; RNA polymerase II transcription initiation pathway; ribosome biogenesis pathway; ASSOCIATED WITH human immunodeficiency virus infectious disease (ortholog); FOUND IN MLL1 complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 2 | 33528388 | 33532395 | Rat | 141 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1312045 | Tex10 | testis expressed 10 | FOUND IN MLL1 complex (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione; 4,4'-sulfonyldiphenol | 5 | 67557770 | 67603904 | Rat | 75 | description | gene, protein-coding, PROVISIONAL [RefSeq] |