| 621017 | Lyn | LYN proto-oncogene, Src family tyrosine kinase | ENCODES a protein that exhibits enzyme binding; gamma-tubulin binding; glycosphingolipid binding; INVOLVED IN cellular response to heat; cytokine production; histamine secretion by mast cell; PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; erythro poietin signaling pathway; ASSOCIATED WITH Cardiomegaly; endometriosis; Parkinsonism; FOUND IN adherens junction; glutamatergic synapse; integrin alpha2-beta1 complex; INTERACTS WITH (S)-AMPA; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 21437127 | 21553097 | Rat | 499 | symbol , old_gene_name , PhenoGen , name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1304754 | Hcls1 | hematopoietic cell specific Lyn substrate 1 | ENCODES a protein that exhibits protein kinase binding (ortholog); protein-containing complex binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN actin filament organization (ortholog); cellular response to cytokine stimulus (ortholog); ery throcyte differentiation (ortholog); ASSOCIATED WITH rheumatoid arthritis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; alpha-Zearalanol | 11 | 77322873 | 77346333 | Rat | 143 | name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1312017 | Lynx1 | Ly6/neurotoxin 1 | ENCODES a protein that exhibits acetylcholine receptor binding (ortholog); acetylcholine receptor inhibitor activity (ortholog); acetylcholine receptor regulator activity (ortholog); INVOLVED IN regulation of neurotransmitter receptor activity (ortholog); synaptic transmission, cholinergic (ortholog ); FOUND IN membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 7 | 108521783 | 108527012 | Rat | 103 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1304643 | Aste1 | asteroid structure-specific endonuclease 1 | ENCODES a protein that exhibits 3' overhang single-stranded DNA endodeoxyribonuclease activity (ortholog); single-stranded DNA endodeoxyribonuclease activity (ortholog); INVOLVED IN double-strand break repair via homologous recombination (ortholog); double-strand break repair via nonhomologous end j oining (ortholog); ASSOCIATED WITH Lynch syndrome (ortholog); mismatch repair cancer syndrome (ortholog); INTERACTS WITH 17beta-estradiol; benzo[a]pyrene; bisphenol A | 8 | 114905349 | 114923775 | Rat | 48 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2465 | Cyp2a3 | cytochrome P450, family 2, subfamily a, polypeptide 3 | ENCODES a protein that exhibits heme binding (inferred); iron ion binding (inferred); metal ion binding (inferred); INVOLVED IN response to stilbenoid (ortholog); PARTICIPATES IN phase I biotransformation pathway via cytochrome P450; retinol metabolic pathway; vitamin A deficiency pathway; ASSOCIATE D WITH autism spectrum disorder (ortholog); Experimental Liver Neoplasms (ortholog); Lynch syndrome (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); INTERACTS WITH (S)-nicotine; 17beta-estradiol; 1H-pyrazole | 1 | 91299584 | 91307650 | Rat | 202 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2322129 | E2f4 | E2F transcription factor 4 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN animal organ morphogenesis (ortholog); blood circulation (ortholog); cell volume homeostasis (ortholog); ASSOCIATED W ITH Disease Progression (ortholog); Lynch syndrome (ortholog); otitis media (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2-acetamidofluorene | 19 | 50084335 | 50091731 | Rat | 149 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1310977 | Epm2aip1 | EPM2A interacting protein 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN positive regulation of glycogen (starch) synthase activity (ortholog); positive regulation of glycogen biosynthetic process (ortholog); response to insulin (ortholog); ASSOCIATED WITH hereditary nonpolyposis colorectal cancer type 2 (ortholog); Lynch syndrome (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of endoplasmic reticulum membrane (ortholog); nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 120112265 | 120119613 | Rat | 122 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 628832 | Kcng3 | potassium voltage-gated channel modifier subfamily G member 3 | ENCODES a protein that exhibits potassium channel regulator activity; INVOLVED IN regulation of potassium ion transport; regulation of potassium ion transmembrane transport (ortholog); ASSOCIATED WITH Lynch syndrome (ortholog); FOUND IN endoplasmic reticulum (or tholog); plasma membrane (ortholog); voltage-gated potassium channel complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 6 | 16803842 | 16851791 | Rat | 115 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 68940 | Kcnk12 | potassium two pore domain channel subfamily K member 12 | ENCODES a protein that exhibits identical protein binding (ortholog); potassium channel activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN monoatomic ion transmembrane transport (inferred); monoatomic ion transport (inferred); potassium ion transmembrane transport (infe rred); ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); Lynch syndrome (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil | 6 | 12492609 | 12544250 | Rat | 95 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306234 | Lrrfip2 | LRR binding FLII interacting protein 2 | ENCODES a protein that exhibits LRR domain binding (ortholog); INVOLVED IN MyD88-dependent toll-like receptor 4 signaling pathway (ortholog); MyD88-independent toll-like receptor signaling pathway (ortholog); obsolete positive regulation of NF-kappaB transcription factor activity (ortholog); ASSOCIA TED WITH Lynch syndrome 1 (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 8 | 119969908 | 120071270 | Rat | 71 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 3215 | Nudc | nuclear distribution C, dynein complex regulator | INVOLVED IN nuclear migration; response to peptide hormone; mitotic metaphase chromosome alignment (ortholog); PARTICIPATES IN M phase pathway; ASSOCIATED WITH Lynch syndrome (ortholog); obesity (ortholog); FOUND IN cytoplasm (ortholog); midbody (ortholog); mito tic spindle (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 3-chloropropane-1,2-diol; ammonium chloride | 5 | 151041878 | 151055260 | Rat | 124 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3374 | Ppm1b | protein phosphatase, Mg2+/Mn2+ dependent, 1B | ENCODES a protein that exhibits phosphoprotein phosphatase activity (ortholog); protein serine/threonine phosphatase activity (ortholog); INVOLVED IN N-terminal protein myristoylation (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholog); negative regulation of defens e response to virus (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; ASSOCIATED WITH hypotonia-cystinuria syndrome (ortholog); Lynch syndrome (ortholog); Myocardial Ischemia (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; aconitine | 6 | 15399559 | 15460301 | Rat | 175 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621104 | Slc22a25 | solute carrier family 22, member 25 | ENCODES a protein that exhibits secondary active transmembrane transporter activity (ortholog); short-chain fatty acid transmembrane transporter activity (ortholog); transmembrane transporter activity (ortholog); INVOLVED IN hormone transport (ortholog); short-chain fatty acid transmembrane transpor t (ortholog); sodium-independent organic anion transport (ortholog); ASSOCIATED WITH Lynch syndrome (ortholog); mismatch repair cancer syndrome (ortholog); FOUND IN basolateral plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-methylumbelliferone sulfate; 6-propyl-2-thiouracil | 1 | 214767837 | 214956535 | Rat | 104 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1596058 | Taf1b | TATA-box binding protein associated factor, RNA polymerase I subunit B | ENCODES a protein that exhibits RNA polymerase I core promoter sequence-specific DNA binding (ortholog); INVOLVED IN regulation of DNA-templated transcription (ortholog); RNA polymerase I preinitiation complex assembly (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; ASSOCIATED WI TH Lynch syndrome (ortholog); mismatch repair cancer syndrome (ortholog); orofacial cleft 1 (ortholog); FOUND IN nucleolus (ortholog); RNA polymerase I core factor complex (ortholog); RNA polymerase transcription factor SL1 complex (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; bisphenol A | 6 | 46845571 | 46923209 | Rat | 86 | description | gene, protein-coding, PROVISIONAL [RefSeq] |