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Genes search result for Rattus norvegicus
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23 records found for search term Lepr
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
3001Leprleptin receptorENCODES a protein that exhibits peptide hormone binding; protein-hormone receptor activity; identical protein binding (ortholog); INVOLVED IN angiogenesis; cellular response to acetate; cellular response to butyrate; PARTICIPATES IN leptin system pathway; triacylglycerol metabolic pathway; altered l5121409735121593201Rat741symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
11570565Leprcpleptin receptor;corpulentASSOCIATED WITH increased body mass index; increased circulating leptin levelRat2symbol , old_gene_symbolgene, allele
13432153Leprfaleptin receptor; fa mutantASSOCIATED WITH abnormal calcium ion homeostasis; abnormal glucose tolerance; abnormal insulin secretion; ASSOCIATED WITH Hyperphagia; Insulin Resistance; obesityRat40symbol , old_gene_symbolgene, allele
12910515Leprem1leptin receptor; TALEN induced mutant 1This allele was produced by injecting TALEN targeting the sequence of rat Lepr into SD embryos. The resulting mutation is a 57-bp deletion.Ratsymbol , description , old_gene_symbolgene, allele
12910518Leprem2leptin receptor; TALEN induced mutant 2ASSOCIATED WITH obesityRat1symbol , description , old_gene_symbolgene, allele
12910546Leprem3leptin receptor; TALEN induced mutant 3ASSOCIATED WITH impaired glucose tolerance; increased circulating alanine transaminase level; increased circulating aspartate transaminase level; ASSOCIATED WITH obesityRat7symbol , description , old_gene_symbolgene, allele
9835400Leprm1Rllleptin receptor; mutant 1, Rudolph L. LeibelThis allele was found in F2 progeny of BNx13M and WKYx13M; substitution of a nucleotide at 880 (A-C) results in Gln-Pro at position 269Ratsymbol , old_gene_symbolgene, allele
6484701Leprem2Mcwileptin receptor; zinc finger nuclease induced mutant 2, Medical College of WisconsinASSOCIATED WITH abnormal glomerular filtration barrier morphology; glomerulosclerosis; impaired glucose tolerance; ASSOCIATED WITH chronic kidney disease; glucose intolerance; hypertensionRat22symbol , old_gene_symbolgene, allele
21079476Leprem4Lizhleptin receptor; CRISPR/Cas9 induced mutant 4, LizhASSOCIATED WITH decreased bone mineral density; decreased trabecular bone volume; expanded mesangial matrix; ASSOCIATED WITH Dyslipidemias; glucose intolerance; hyperglycemiaRat17symbol , descriptiongene, allele
621034Leprotleptin receptor overlapping transcriptENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN negative regulation of growth hormone receptor signaling pathway (ortholog); negative regulation of protein localization to cell surface (ortholog); negative regulation of receptor signaling pathway via JAK-STAT (orth5121405170121417273Rat80symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
728330Lepr_v1leptin receptor, variant 1ENCODES an splice that exhibits peptide hormone binding; protein-hormone receptor activity; INVOLVED IN leptin-mediated signaling pathway; positive regulation of MAPK cascade; PARTICIPATES IN leptin system pathwayRat7symbolgene, splice
728313Lepr_v2leptin receptor, variant 2ENCODES an splice that exhibits peptide hormone binding; protein-hormone receptor activity; INVOLVED IN cellular response to acetaldehyde; leptin-mediated signaling pathway; positive regulation of MAPK cascade; PARTICIPATES IN leptin system pathway; altered leptin system pathway; obesity pathway; INRat13symbolgene, splice
1307168Leprotl1leptin receptor overlapping transcript-like 1ENCODES a protein that exhibits identical protein binding (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 2,4-dinitrotoluene; amphetamine; bisphenol A166474414864756776Rat72symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
628823P3h1prolyl 3-hydroxylase 1ENCODES a protein that exhibits dioxygenase activity (inferred); iron ion binding (inferred); L-ascorbic acid binding (inferred); INVOLVED IN positive regulation of neuron projection development; bone development (ortholog); collagen fibril organization (ortholog); ASSOCIATED WITH BCARD syndrome (or5138127240138141974Rat113old_gene_name , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1304568P3h2prolyl 3-hydroxylase 2ENCODES a protein that exhibits procollagen-proline 3-dioxygenase activity; INVOLVED IN collagen metabolic process; peptidyl-proline hydroxylation; negative regulation of cell population proliferation (ortholog); ASSOCIATED WITH genetic disease (ortholog); High Myopia with Cataract and Vitreoretinal118813908688280221Rat130old_gene_name , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
1305699P3h3prolyl 3-hydroxylase 3ENCODES a protein that exhibits dioxygenase activity (inferred); G protein-coupled receptor activity (inferred); iron ion binding (inferred); INVOLVED IN collagen biosynthetic process (ortholog); negative regulation of cell population proliferation (ortholog); peptidyl-lysine hydroxylation (ortholog4159332514159348428Rat100old_gene_name , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
620767P3h4prolyl 3-hydroxylase family member 4INVOLVED IN bone remodeling (ortholog); collagen biosynthetic process (ortholog); collagen fibril organization (ortholog); FOUND IN synaptonemal complex; catalytic complex (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithi108583852885845476Rat89old_gene_name , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
2304195P3h3Tn(sb-T2/Bart3)2.310Mcwiprolyl 3-hydroxylase 3; transposon insertion 2.310, Medical College of Wisconsinthis mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 1st intron of the Leprel2 geneRatold_gene_name , description , old_gene_symbolgene, allele
620501Batf3basic leucine zipper ATF-like transcription factor 3ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN dendritic cell differentiation 13105220782105232365Rat129descriptiongene, protein-coding, VALIDATED [RefSeq]
2321506Ccdc122coiled-coil domain containing 122ASSOCIATED WITH leprosy (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; bromobenzene155881692758899200Rat39descriptiongene, protein-coding, VALIDATED [RefSeq]
1311475Ccdc88bcoiled-coil and HOOK domain protein 88BINVOLVED IN defense response to protozoan (ortholog); positive regulation of cytokine production (ortholog); positive regulation of T cell activation (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; neurotrophic factor signaling pathway; ASSOCIATED WITH lepr1213466139213482099Rat97descriptiongene, protein-coding, VALIDATED [RefSeq]
1310185Lacc1laccase domain containing 1ENCODES a protein that exhibits adenosine deaminase activity (ortholog); guanosine phosphorylase activity (ortholog); oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor (ortholog); INVOLVED IN nucleotide-binding oligomerization domain containing 2 signa155879947758816840Rat119descriptiongene, protein-coding, VALIDATED [RefSeq]
1309167Ripk2receptor-interacting serine-threonine kinase 2ENCODES a protein that exhibits CARD domain binding (ortholog); caspase binding (ortholog); identical protein binding (ortholog); INVOLVED IN adaptive immune response (ortholog); apoptotic process (ortholog); canonical NF-kappaB signal transduction (ortholog); PARTICIPATES IN interleukin-12 signalin53442857334459808Rat278descriptiongene, protein-coding, PROVISIONAL [RefSeq]