| 1310312 | Isg15 | ISG15 ubiquitin-like modifier | ENCODES a protein that exhibits integrin binding (ortholog); protein tag activity (ortholog); INVOLVED IN defense response to bacterium (ortholog); defense response to virus (ortholog); innate immune response (ortholog); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pa thway; ASSOCIATED WITH Experimental Diabetes Mellitus; Carcinogenesis (ortholog); Chronic Hepatitis C (ortholog); FOUND IN extracellular region (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol | 5 | 172066369 | 172067656 | Rat | 325 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1594396 | Trim25 | tripartite motif-containing 25 | ENCODES a protein that exhibits RIG-I binding (ortholog); transcription coactivator activity (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN response to estrogen; response to vitamin D; antiviral innate immune response (ortholog); PARTICIPATES IN influenza A pathway; Retinoic a cid-inducible gene (RIG) I-like receptor signaling pathway; ASSOCIATED WITH Joubert syndrome (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic stress granule (ortholog); cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 74310024 | 74328473 | Rat | 204 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311352 | Trim80 | tripartite motif protein 80 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN immune system process (inferred); innate immune response (inferred); FOUND IN cytoplasm (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 3-chloropropan e-1,2-diol | 10 | 101181797 | 101190122 | Rat | 18 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1307960 | Ube2l6 | ubiquitin-conjugating enzyme E2L 6 | ENCODES a protein that exhibits ISG15 transferase activity (ortholog); ubiquitin binding (ortholog); ubiquitin-like protein transferase activity (ortholog); INVOLVED IN innate immune response (ortholog); ISG15-protein conjug ation (ortholog); modification-dependent protein catabolic process (ortholog); PARTICIPATES IN Parkinson's disease pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Human Influenza (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 3 | 90279705 | 90294721 | Rat | 171 | old_gene_name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308323 | Uba7 | ubiquitin-like modifier activating enzyme 7 | ENCODES a protein that exhibits ISG15 activating enzyme activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN innate immune response (ortholog); ISG15-protein conjugation (ortholog); modificatio n-dependent protein catabolic process (ortholog); PARTICIPATES IN Parkinson's disease pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH intellectual disability (ortholog); squamous cell carcinoma (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate | 8 | 117543902 | 117552709 | Rat | 161 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2324438 | Ube2e1 | ubiquitin-conjugating enzyme E2E 1 | ENCODES a protein that exhibits ISG15 transferase activity (ortholog); ubiquitin conjugating enzyme activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN ISG15-protein conjugation (ortholog); po sitive regulation of transcription by RNA polymerase II (ortholog); protein K48-linked ubiquitination (ortholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); juvenile rheumatoid arthritis (ortholog); skin disease (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); ubiquitin ligase complex (ortholog); INTERACTS WITH atrazine; bisphenol A; paracetamol | 15 | 9870528 | 9924194 | Rat | 88 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305644 | Ube2e2 | ubiquitin-conjugating enzyme E2E 2 | ENCODES a protein that exhibits ISG15 transferase activity (ortholog); ubiquitin conjugating enzyme activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN DNA damage response (ortholog); ISG15-pr otein conjugation (ortholog); positive regulation of G1/S transition of mitotic cell cycle (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH hepatocellular adenoma (ortholog); hepatocellular carcinoma (ortholog); type 2 diabetes mellitus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene | 15 | 9411067 | 9688731 | Rat | 124 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1359153 | Usp18 | ubiquitin specific peptidase 18 | ENCODES a protein that exhibits ISG15-specific peptidase activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); negative regulation of type I interferon-mediated signaling pathway (ortholog); regulati on of inflammatory response (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); Aicardi-Goutieres syndrome (ortholog); Chronic Hepatitis C (ortholog); FOUND IN cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 156143770 | 156171292 | Rat | 217 | description | gene, protein-coding, VALIDATED [RefSeq] |