ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN cellular response to chemokine (ortholog); dendritic cell migration (ortholog); immunological synapse formation (ortholog); ASSOCIATED WITH type 1 diabetes mellitus; atopic dermatitis (ortholog); autos
omal dominant intellectual developmental disorder 2 (ortholog); FOUND IN cell leading edge (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3H-1,2-dithiole-3-thione