Gene: Dock8 (dedicator of cytokinesis 8) Rattus norvegicus
Symbol: Dock8
Name: dedicator of cytokinesis 8
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN dendritic cell migration (ortholog); immunological synapse formation (ortholog); memory T cell proliferation (ortholog); ASSOCIATED WITH Job Syndrome (ortholog); MENTAL RETARDATION, AUTOSOMAL DOMINANT 2 (ortholog); FOUND IN cell leading edge (ortholog); membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dedicator of cytokinesis protein 8; LOC499337; MGC116414; similar to dedicator of cytokinesis 8
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01242,934,682 - 243,153,472+NCBI
Rat Cytogenetic Map1q51 NCBI
RGSC Genome Assembly v5.01250,200,507 - 250,417,771+NCBI
RGSC Genome Assembly v3.41228,441,384 - 228,634,717+NCBI
Rat Celera Assembly1219,852,410 - 220,042,463+NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Dock8
Entrez Gene
Ensembl Gene
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1561588
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2015-07-07
Status: ACTIVE