| 2278 | Cast | calpastatin | ENCODES a protein that exhibits calcium-dependent cysteine-type endopeptidase inhibitor activity; protease binding; INVOLVED IN animal organ regeneration; egg activation; liver development; PARTICIPATES IN the proteolytic pathway involving calcium-dependent proteases; ASSOCIATED WITH alcohol use dis order; Brain Hypoxia-Ischemia; Brain Injuries; FOUND IN membrane; postsynaptic density; cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione | 2 | 5707633 | 5817213 | Rat | 212 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 628733 | Erc1 | ELKS/RAB6-interacting/CAST family member 1 | ENCODES a protein that exhibits PDZ domain binding; small GTPase binding (ortholog); structural constituent of presynaptic active zone (ortholog); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); regulation of calcium-dependent activation of synaptic vesicle fus ion (ortholog); regulation of DNA-templated transcription (ortholog); PARTICIPATES IN interleukin-1 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH Macrocephaly, Dysmorphic Facies, and Psychomotor Retardation (ortholog); FOUND IN membrane; postsynaptic density; presynaptic active zone cytoplasmic component; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 4 | 154435936 | 154727987 | Rat | 154 | name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 708372 | Erc2 | ELKS/RAB6-interacting/CAST family member 2 | ENCODES a protein that exhibits PDZ domain binding; protein-containing complex binding; structural constituent of presynaptic active zone (ortholog); INVOLVED IN synapse organization; regulation of calcium-dependent activation of synaptic vesicle fusion (ortholog); regulation of presynaptic cytosoli c calcium ion concentration (ortholog); FOUND IN Golgi-associated vesicle; growth cone; neuronal cell body; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 16 | 2819399 | 3680258 | Rat | 144 | name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1304774 | Castor1 | cytosolic arginine sensor for mTORC1 subunit 1 | ENCODES a protein that exhibits arginine binding (ortholog); identical protein binding (ortholog); molecular sensor activity (ortholog); INVOLVED IN cellular response to amino acid starvation (ortholog); cellular response to L-arginine (ortholog); negative regulation of TORC1 signaling (ortholog); P ARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (ortholog); GATOR2 complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1 | 14 | 83309710 | 83314123 | Rat | 90 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304672 | Castor2 | cytosolic arginine sensor for mTORC1 subunit 2 | ENCODES a protein that exhibits arginine binding (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to L-arginine (ortholog); negative regulation of TORC1 signaling (ortholog); PARTICIPATES IN mTOR signaling pathway; FOUND IN cytosol (ortholog); GATOR2 complex (ortholog) ; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 12 | 28213927 | 28256593 | Rat | 65 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1563533 | Casz1 | castor zinc finger 1 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of amacrine cell differentiation (ortholog); negative regul ation of cell differentiation (ortholog); negative regulation of neuron differentiation (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); autism spectrum disorder (ortholog); chromosome 1p36 deletion syndrome (ortholog); FOUND IN chromatin (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; alpha-Zearalanol; atrazine | 5 | 164527083 | 164677037 | Rat | 128 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1304918 | Asf1b | anti-silencing function 1B histone chaperone | ENCODES a protein that exhibits histone binding (ortholog); histone chaperone activity (ortholog); INVOLVED IN blastocyst hatching (ortholog); nucleosome assembly (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH breast cancer (ortholog); cast span>ration-resistant prostate carcinoma (ortholog); hepatocellular carcinoma (ortholog); FOUND IN chromatin (ortholog); nucleoplasm (ortholog); protein-containing complex (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 19 | 41085786 | 41100352 | Rat | 200 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1307783 | Ccne2 | cyclin E2 | ENCODES a protein that exhibits protein kinase binding; cyclin-dependent protein serine/threonine kinase regulator activity (ortholog); INVOLVED IN chromosome organization involved in meiotic cell cycle (ortholog); DNA replication initiation (ortholog); homologous chromosome pairing at meiosis (orth olog); PARTICIPATES IN G1/S transition pathway; cell cycle pathway, mitotic; measles pathway; ASSOCIATED WITH castration-resistant prostate carcinoma (ortholog); endometriosis (ortholog); head and neck squamous cell carcinoma (ortholog); FOUND IN cyclin E2-CDK2 complex (ortholog); INTERACTS WITH 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 29082169 | 29094879 | Rat | 322 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1310461 | Cenpk | centromere protein K | INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH castration-resistant prostate carcinoma (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide | 2 | 37094163 | 37155158 | Rat | 126 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306794 | Chd1 | chromodomain helicase DNA binding protein 1 | ENCODES a protein that exhibits histone H3K4me3 reader activity (ortholog); INVOLVED IN chromatin remodeling (ortholog); gene expression (ortholog); host-mediated activation of viral transcription (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH cast '>castration-resistant prostate carcinoma (ortholog); Colorectal Neoplasms (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN cytoplasm (ortholog); nuclear chromosome (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 1 | 65334905 | 65402270 | Rat | 129 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 69275 | Mpeg1 | macrophage expressed 1 | ENCODES a protein that exhibits pore-forming activity (ortholog); wide pore channel activity (ortholog); INVOLVED IN antibacterial innate immune response (ortholog); antigen processing and presentation of exogenous peptide antigen (ortholog); antigen processing and presentation of exogenous peptide antigen via MHC class I (ortholog); ASSOCIATED WITH Experimental Liver Neoplasms (ortholog); Immunodeficiency 77 (ortholog); multicentric Castleman disease (ortholog); FOUND IN cytoplasmic vesicle (ortholog); endolysosome (ortholog); phagocytic vesicle (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 1 | 218876848 | 218881364 | Rat | 141 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307952 | Nuf2 | NUF2 component of NDC80 kinetochore complex | ENCODES a protein that exhibits microtubule binding (ortholog); INVOLVED IN attachment of spindle microtubules to kinetochore (ortholog); ASSOCIATED WITH breast cancer (ortholog); castration-resistant prostate carcinoma (ortholog); colorectal cancer (ortholog); FOUND IN kinetochore (ortholog); Ndc80 complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1-naphthyl isothiocyanate; 17beta-estradiol | 13 | 84226448 | 84290957 | Rat | 204 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1560596 | Trim24 | tripartite motif-containing 24 | ENCODES a protein that exhibits chromatin binding (ortholog); estrogen response element binding (ortholog); histone H3K23ac reader activity (ortholog); INVOLVED IN response to peptide hormone; calcium ion homeostasis (ortholog); cellular response to estrogen stimulus (ortholog); PARTICIPATES IN hist one modification pathway; retinoic acid signaling pathway; ASSOCIATED WITH castration-resistant prostate carcinoma (ortholog); Experimental Liver Cirrhosis (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (ortholog); euchromatin (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene | 4 | 67534240 | 67659014 | Rat | 221 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1308451 | Zfp217 | zinc finger protein 217 | ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN negative regulation of DNA-templa ted transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH castration-resistant prostate carcinoma (ortholog); FOUND IN histone deacetylase complex (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; bisphenol A; Cuprizon | 3 | 179309178 | 179349853 | Rat | 103 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307136 | Zfp367 | zinc finger protein 367 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH castration-resistant prostate carcinoma (ortholog); Colorectal Neoplasms (ortholog); Ne oplasm Invasiveness (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 4,4'-diaminodiphenylmethane | 17 | 970896 | 990025 | Rat | 147 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 708342 | Parm1 | prostate androgen-regulated mucin-like protein 1 | FOUND IN early endosome (ortholog); Golgi apparatus (ortholog); late endosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aconitine | 14 | 16752541 | 16861570 | Rat | 121 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |