| 2192 | Bax | BCL2 associated X, apoptosis regulator | ENCODES a protein that exhibits BH domain binding; heat shock protein binding; protein-containing complex binding; INVOLVED IN cellular respiration; cellular response to hydrogen peroxide; cerebral cortex development; PARTICIPATES IN intrinsic apoptotic pathway; ceramide signaling pathway; syndecan signaling pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome 1; acute kidney failure; Acute Lung Injury; FOUND IN cytoplasm; cytosol; mitochondrial membrane; INTERACTS WITH (+)-catechin; (+)-pilocarpine; (+)-sesamin | 1 | 105076472 | 105081906 | Rat | 3536 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1561847 | Bax-ps1 | BCL2 associated X, apoptosis regulator, pseudogene 1 | INTERACTS WITH bisphenol A | 8 | 106525986 | 106526581 | Rat | 1 | symbol , old_gene_name , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1596776 | Bax-ps2 | BCL2-associated X protein, pseudogene 2 | | 10 | 87032488 | 87033310 | Rat | | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 15003497 | Bax-ps2 | BCL2-associated X protein, pseudogene 2 | | | | | Rat | | symbol , PhenoGen | gene, processed_pseudogene |
| 728325 | Bax_v1 | BCL2 associated X, apoptosis regulator, variant 1 | INVOLVED IN positive regulation of apoptotic process; PARTICIPATES IN intrinsic apoptotic pathway | | | | Rat | 2 | symbol , old_gene_symbol | gene, splice |
| 728332 | Bax_v2 | BCL2 associated X, apoptosis regulator, variant 2 | PARTICIPATES IN intrinsic apoptotic pathway | | | | Rat | 1 | symbol , old_gene_symbol | gene, splice |
| 1359409 | Tmbim1 | transmembrane BAX inhibitor motif containing 1 | ENCODES a protein that exhibits death receptor binding (ortholog); INVOLVED IN negative regulation of catalytic activity (ortholog); negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of Fas signaling pathway (ortholog); ASSOCIATED WITH cerebrotendinous xanthomatosis (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN endosome membrane (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine | 9 | 83320972 | 83338469 | Rat | 122 | old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 735173 | Tmbim4 | transmembrane BAX inhibitor motif containing 4 | INVOLVED IN locomotory behavior (ortholog); negative regulation of apoptotic process (ortholog); negative regulation of neuron apoptotic process (ortholog); ASSOCIATED WITH ovarian cyst (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); Golgi apparatus (ortholog); Golgi stack (ortholog) ; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; flutamide | 7 | 57604275 | 57618861 | Rat | 79 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 3842 | Tmbim6 | transmembrane BAX inhibitor motif containing 6 | ENCODES a protein that exhibits endoribonuclease inhibitor activity (ortholog); enzyme binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN lung development; spermatogenesis; cellular response to unfolded protein (ortholog); ASSOCIATED WITH invasive ductal carcinoma; Reperfus ion Injury; Subarachnoid Hemorrhage; FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 7 | 132405217 | 132422492 | Rat | 145 | old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306626 | Tmbim7 | transmembrane BAX inhibitor motif containing 7 | INVOLVED IN calcium ion transmembrane transport (inferred); FOUND IN membrane (inferred); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; indole-3-methanol | 4 | 31421371 | 31454319 | Rat | 16 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |
| 2581 | Esr1 | estrogen receptor 1 | ENCODES a protein that exhibits DNA binding; enzyme binding; estrogen binding; INVOLVED IN baculum development; cellular response to estradiol stimulus; cellular response to estrogen stimulus; PARTICIPATES IN estrogen signaling pathway; insulin-like growth factor signaling pathway; phosphatidylinosi tol 3-kinase-Akt signaling pathway; ASSOCIATED WITH abnormal body size; abnormal female reproductive system morphology; abnormal male reproductive system morphology; ASSOCIATED WITH cryptorchidism; Diabetic Nephropathies; Experimental Diabetes Mellitus; FOUND IN nucleus; perikaryon; perinuclear region of cytoplasm; INTERACTS WITH (R,R,R)-alpha-tocopherol; (S)-naringenin; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane | 1 | 43511685 | 43904454 | Rat | 2347 | GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 61797 | Prkn | parkin RBR E3 ubiquitin protein ligase | ENCODES a protein that exhibits protein kinase binding; protein-containing complex binding; actin binding (ortholog); INVOLVED IN cellular response to hydrogen sulfide; cellular response to L-glutamate; cellular response to L-glutamine; PARTICIPATES IN altered mitochondrial autophagy pathway; mitoch ondrial autophagy pathway; Parkinson's disease pathway; ASSOCIATED WITH Experimental Liver Cirrhosis; metabolic dysfunction-associated steatohepatitis; Parkinson's disease; FOUND IN axon; cytoplasm; cytosol; INTERACTS WITH 1,3-dichloropropan-2-ol; 3-chloropropane-1,2-diol; 3-methyladenine | 1 | 51236410 | 52430242 | Rat | 851 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1303107 | Vkorc1 | vitamin K epoxide reductase complex, subunit 1 | ENCODES a protein that exhibits vitamin-K-epoxide reductase (warfarin-insensitive) activity; vitamin-K-epoxide reductase (warfarin-sensitive) activity; INVOLVED IN regulation of blood coagulation; blood coagulation (ortholog); bone development (ortholog); PARTICIPATES IN acenocoumarol pharmacodynami cs pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; ASSOCIATED WITH Aortic Calcification; warfarin sensitivity; Aortic Rupture (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum lumen (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1,4-dithiothreitol; 17alpha-ethynylestradiol | 1 | 191932969 | 191935490 | Rat | 242 | GenBank Protein | gene, protein-coding, REVIEWED [RefSeq] |