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Strain Registration

Strain: LEW-Nek8lpk/Arc

Symbol: LEW-Nek8lpk/Arc
Strain: LEW-Nek8lpk
Substrain: Arc
RGD ID: 42721974
Citation ID: RRID:RGD_42721974
Ontology ID: RS:0004861
Alleles: Nek8lpkArc
Also Known As: LEW-Nek8^[lpk]/Arc
Type: mutant
Available Source: Not Available
Description: The Lewis Polycystic Kidney (LPK) rat is a spontaneous mutant identified in the LEW colony (LEW/SsNArc) maintained at Animal Resources Centre in Canning Vale, WA 6970 AUSTRALIA. The causal gene is identified as a non-synonymous mutation R650C in the NIMA (never in mitosis gene a)- related kinase 8 ( Nek8) gene.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21063,060,868 - 63,073,546RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01065,404,489 - 65,439,059RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01066,196,993 - 66,230,588RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41064,458,886 - 64,470,044RGD_MAPPER_PIPELINERGSC3.4





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Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. A novel mutation causing nephronophthisis in the Lewis polycystic kidney rat localises to a conserved RCC1 domain in Nek8. McCooke JK, etal., BMC Genomics. 2012 Aug 16;13:393. doi: 10.1186/1471-2164-13-393.

Region


Additional Information