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Strain Registration

Strain: DA.E3-(D4Wox49-D4Got136)/Rhd

Symbol: DA.E3-(D4Wox49-D4Got136)/Rhd
Strain: DA.E3-(D4Wox49-D4Got136)
Substrain: Rhd
RGD ID: 2324631
Citation ID: RRID:RGD_2324631
Ontology ID: RS:0002405
Alleles: Clec4a3
Also Known As: DA.E3-Pia7; DA.E3-Pia7; DA.E3-(D4Wox49-D4Got136)/Rhd
Type: congenic
Available Source: Not Available
Origination: Medical Inflammation Research, Karolinska Institutet, Stockholm, Sweden.
Description: This congenic strain was obtained by the conventional backcross breeding to the parental DA strain with the negative selection of all known Pia QTLs and positive selection of microsatellite markers.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24155,828,194 - 157,232,313RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.04155,414,290 - 156,945,571RGD_MAPPER_PIPELINERnor6.0
Rnor_5.04222,438,489 - 223,964,695RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.44159,060,677 - 160,528,447RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Complex genetic control in a rat model for rheumatoid arthritis. Nordquist N, etal., J Autoimmun 2000 Dec;15(4):425-32.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. Finemapping of the arthritis QTL Pia7 reveals co-localization with Oia2 and the APLEC locus. Rintisch C, etal., Genes Immun. 2010 Apr;11(3):239-45. Epub 2010 Mar 4.

Region

Position Markers

Flank 1 / 1 (D4Wox49)
Rat AssemblyChrPosition (strand)Source
mRatBN7.24155,828,194 - 155,828,348 (+)MAPPER
Rnor_6.04155,414,290 - 155,414,443NCBI
Rnor_5.04222,438,489 - 222,438,642UniSTS
RGSC_v3.44159,060,677 - 159,060,830UniSTS
Celera4144,647,353 - 144,647,506UniSTS
Cytogenetic Map4 RGD

Flank 2 / 1 (D4Got136)
Rat AssemblyChrPosition (strand)Source
mRatBN7.24157,232,171 - 157,232,313 (+)MAPPER
Rnor_6.04156,945,430 - 156,945,571NCBI
Rnor_5.04223,964,554 - 223,964,695UniSTS
RGSC_v3.44160,528,306 - 160,528,447UniSTS
RGSC_v3.44160,528,306 - 160,528,447RGD
RGSC_v3.14160,773,242 - 160,773,383RGD
Celera4145,973,618 - 145,973,765UniSTS
RH 3.4 Map41003.8UniSTS
RH 3.4 Map41003.8RGD
Cytogenetic Map4q42UniSTS
Strain QTL Data
Symbol Name Trait
Pia7 Pristane induced arthritis QTL 7 joint integrity trait   (VT:0010548)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease these are protected from both pristane and oil induced arthritis 2324629
strain_other this region overlaps with the region covered by DA.PVG-(D4Rat141-D4Mgh11) congenic strain that has the Clec4a3 gene 2324629
strain_other have have less numbers of alpha, beta T cells but a higher number of B cells in the leukocytes as compared to the DA parental strain 2324629