RGD Reference Report - Calcium-ion binding by the potential calcium-ion-binding protein, p9Ka. - Rat Genome Database

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Calcium-ion binding by the potential calcium-ion-binding protein, p9Ka.

Authors: Barraclough, R  Gibbs, F  Smith, JA  Haynes, GA  Rudland, PS 
Citation: Barraclough R, etal., Biochem Biophys Res Commun. 1990 Jun 15;169(2):660-6.
RGD ID: 7205642
Pubmed: PMID:2357224   (View Abstract at PubMed)

p9Ka is a polypeptide of apparent molecular mass 9 kDa, present in cultured rat mammary myoepithelial-like cells, but virtually absent in their parental epithelial cells. mRNA for p9Ka is present in normal rodent tissues. The amino acid sequence of a protein of molecular mass 12 KDa, derived from the nucleotide sequence of the p9Ka gene, is related to that of S-100 protein, a calcium-ion-binding protein. p9Ka, isolated from cultured rat mammary myoepithelial-like cells is now shown to bind calcium ions in vitro suggesting that the derived amino acid sequence is correct, and that an apparent discrepancy between the molecular masses of the predicted and isolated p9Ka does not affect this activity.



Gene Ontology Annotations    Click to see Annotation Detail View

Molecular Function
Object SymbolSpeciesTermQualifierEvidenceWithNotesSourceOriginal Reference(s)
S100a4Ratcalcium ion binding  IDA  RGD 

Objects Annotated

Genes (Rattus norvegicus)
S100a4  (S100 calcium-binding protein A4)


Additional Information