SCL94_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: SCL94_H (Serum cholesterol level QTL 94 (human)) Homo sapiens

Symbol: SCL94_H
Name: Serum cholesterol level QTL 94 (human)
RGD ID: 1559346
Trait: Lipid level
Measurement Type: total cholesterol
LOD Score: 1.54
P Value: 0.004
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371917,417,129 - 43,417,129RGDGRCh37
Build 361922,108,969 - 48,108,969RGDNCBI36
Cross Type: Not Available
Population Stats: 612 individuals consisting of 65 Amish individuals with type 2 diabetes, their first and second degree relatives, and spouses



Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. A genome-wide scan of serum lipid levels in the Old Order Amish. Pollin TI, etal., Atherosclerosis 2004 Mar;173(1):89-96.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Peak: (D19S433)
Human AssemblyChrPosition (strand)Source
GRCh371930,417,027 - 30,417,232UniSTS
Build 361935,108,867 - 35,109,072RGD
Celera1927,110,713 - 27,110,918RGD
HuRef1926,924,414 - 26,924,615UniSTS
Marshfield Genetic Map1951.88UniSTS
Marshfield Genetic Map1951.88RGD
deCODE Assembly Map1950.82UniSTS


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_cand_genes LDLR 1559071
qtl_map ABI Prism Linkage Mapping Set; average interval between markers was 9.7 cM 1559071
qtl_population 612 individuals consisting of 65 Amish individuals with type 2 diabetes, their first and second degree relatives, and spouses 1559071
qtl_population_details 28 discrete family groups ranging in size from 3 to 69 individuals yielding 418 parent-offspring pairs, 1175 sib-pairs, 1088 avuncular pairs, and 1072 first cousin pairs used in the linkage analysis 1559071
qtl_statistics_details SOLAR; variance components analysis 1559071