Clk4 (CDC-like kinase 4) - Rat Genome Database

Name: Clk4
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Clk4 (CDC-like kinase 4) Rattus norvegicus

Analyze

Symbol:

Clk4

Name:

CDC-like kinase 4

RGD ID:

1310274

Description:

Predicted to enable protein serine/threonine kinase activity and protein tyrosine kinase activity. Predicted to be involved in regulation of RNA splicing. Predicted to be active in nucleus. Orthologous to human CLK4 (CDC like kinase 4); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

CDC like kinase 4; dual specificity protein kinase CLK4; LOC287269

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CLK4 (CDC like kinase 4)	HGNC	Ensembl, NCBI, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):	Clk4 (CDC like kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Clk4 (CDC like kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CLK4 (CDC like kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CLK4 (CDC like kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Clk4 (CDC like kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CLK4 (CDC like kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CLK4 (CDC like kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Clk4 (CDC like kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CLK4 (CDC like kinase 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	Clk4 (CDC like kinase 4)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	clk4a (CDC-like kinase 4a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	clk4b (CDC-like kinase 4b)	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Doa	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	KNS1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	madd-3	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	Y111B2A.1	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	clk1	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	36,024,364 - 36,042,366 (+)	NCBI		GRCr8
mRatBN7.2	10	35,523,382 - 35,541,387 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	35,524,755 - 35,541,352 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	40,217,344 - 40,235,243 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	39,707,659 - 39,725,558 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	35,211,040 - 35,228,939 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	36,715,565 - 36,733,473 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	36,715,565 - 36,733,133 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	36,487,184 - 36,505,103 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	36,782,792 - 36,800,362 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	36,783,840 - 36,801,409 (+)	NCBI
Celera	10	34,879,664 - 34,897,233 (+)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Ehlers-Danlos syndrome dermatosparaxis type (ISO)

Ehlers-Danlos syndrome spondylodysplastic type 2 (ISO)

genetic disease (ISO)

Sotos syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-palmitoylglycerol (ISO)

5-iodotubercidin (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrolein (ISO)

afimoxifene (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

amitrole (EXP)

Aroclor 1254 (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

choline (ISO)

chrysene (ISO)

cisplatin (ISO)

cocaine (ISO)

copper atom (EXP)

copper(0) (EXP)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

ferric oxide (ISO)

fluoranthene (ISO)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

geldanamycin (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

L-methionine (ISO)

leflunomide (ISO)

methimazole (EXP)

methotrexate (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

phorone (EXP)

resveratrol (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

tamoxifen (ISO)

tetraphene (ISO)

thimerosal (ISO)

titanium dioxide (ISO)

triptonide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

regulation of RNA splicing (IBA,ISO)

Cellular Component

nucleus (IBA,ISO)

Molecular Function

ATP binding (IEA)

protein binding (ISO)

protein serine/threonine kinase activity (IBA,ISO)

protein tyrosine kinase activity (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:9307018	PMID:19168442

Genomics

Comparative Map Data

Clk4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	36,024,364 - 36,042,366 (+)	NCBI		GRCr8
mRatBN7.2	10	35,523,382 - 35,541,387 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	35,524,755 - 35,541,352 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	40,217,344 - 40,235,243 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	39,707,659 - 39,725,558 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	35,211,040 - 35,228,939 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	36,715,565 - 36,733,473 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	36,715,565 - 36,733,133 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	36,487,184 - 36,505,103 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	36,782,792 - 36,800,362 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	36,783,840 - 36,801,409 (+)	NCBI
Celera	10	34,879,664 - 34,897,233 (+)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

CLK4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	178,602,664 - 178,627,050 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	178,602,664 - 178,630,615 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	178,029,665 - 178,054,051 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	177,962,271 - 177,986,660 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	177,962,271 - 177,986,660	NCBI
Celera	5	173,657,123 - 173,681,183 (-)	NCBI		Celera
Cytogenetic Map	5	q35.3	NCBI
HuRef	5	172,756,811 - 172,777,551 (-)	NCBI		HuRef
CHM1_1	5	177,462,038 - 177,486,420 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	179,154,636 - 179,179,025 (-)	NCBI		T2T-CHM13v2.0

Clk4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	51,153,941 - 51,172,597 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	51,152,557 - 51,172,593 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	51,263,114 - 51,281,770 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	51,261,730 - 51,281,766 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	51,076,673 - 51,095,266 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	51,106,594 - 51,125,187 (+)	NCBI		MGSCv36	mm8
Celera	11	55,822,951 - 55,841,544 (+)	NCBI		Celera
Cytogenetic Map	11	B1.3	NCBI
cM Map	11	31.02	NCBI

Clk4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	1,719,963 - 1,747,878 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955408	1,726,283 - 1,747,314 (+)	NCBI	ChiLan1.0	ChiLan1.0

CLK4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	173,542,784 - 173,567,277 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	171,682,324 - 171,709,226 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	173,760,420 - 173,784,851 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	181,017,365 - 181,041,632 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	181,017,365 - 181,037,919 (-)	Ensembl	panpan1.1		panPan2

CLK4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	2,960,161 - 2,986,699 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	2,965,256 - 2,986,658 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	3,104,085 - 3,130,619 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	2,936,551 - 2,963,082 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	2,943,500 - 2,963,082 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	2,907,231 - 2,933,752 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	2,985,795 - 3,012,306 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	3,227,084 - 3,253,609 (+)	NCBI		UU_Cfam_GSD_1.0

Clk4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	113,055,729 - 113,081,781 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936647	67,000 - 88,149 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936647	62,478 - 83,947 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CLK4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	79,693,669 - 79,753,712 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	79,729,460 - 79,752,945 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	81,341,286 - 81,367,964 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CLK4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	80,290,716 - 80,313,200 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	80,288,120 - 80,313,255 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666075	11,602,496 - 11,625,658 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Clk4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624733	41,713,524 - 41,752,822 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Clk4
53 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	123
Count of miRNA genes:	96
Interacting mature miRNAs:	99
Transcripts:	ENSRNOT00000005048
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
634327	Hc4	Hypercalciuria QTL 4	2.4		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	10	1	38328221	Rat
7411611	Foco17	Food consumption QTL 17	18.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	1	42315980	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1	80676123	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	418344	45418344	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	743364	63851208	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5387014	50387014	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5387014	50387014	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5387014	50387014	Rat
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5387014	50387014	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5387014	50387014	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	5801990	62146030	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6154182	73453136	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6357896	96121100	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6375746	51375746	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
9590310	Scort19	Serum corticosterone level QTL 19	6.3	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	11474010	56474010	Rat
9590268	Scort13	Serum corticosterone level QTL 13	3.26	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	11474010	56474010	Rat
9589136	Insul27	Insulin level QTL 27	10.46	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	10	11474010	56474010	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14487011	89062041	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14487011	104060283	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15028513	60430477	Rat
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15275955	60275955	Rat
6893350	Bw99	Body weight QTL 99	0.87	0.16	body mass (VT:0001259)	body weight (CMO:0000012)	1	15906665	60906665	Rat
6893352	Bw100	Body weight QTL 100	0.33	0.6	body mass (VT:0001259)	body weight (CMO:0000012)	1	15906665	60906665	Rat
631532	Cm50	Cardiac mass QTL 50	6.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	17907113	51786432	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18167841	63167841	Rat
2313055	Bw96	Body weight QTL 96	3.6	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	10	19606483	64606483	Rat
2313087	Bmd80	Bone mineral density QTL 80	3.2	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	10	19606483	64606483	Rat
1554317	Bmd4	Bone mineral density QTL 4	9.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	19816042	99406971	Rat
1581497	Esta1	Estrogen-induced thymic atrophy QTL 1			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	21329805	61345413	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22427500	90627625	Rat
631531	Iresp2	Immunoglobin response QTL2	6.3		blood immunoglobulin E amount (VT:0002492)	serum immunoglobulin E level (CMO:0002101)	10	22918268	36400810	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
70224	Eae3	Experimental allergic encephalomyelitis QTL 3	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	26521957	61345413	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	26521957	98003205	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	26521957	98952741	Rat
2300171	Bmd58	Bone mineral density QTL 58	4.9	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	26944628	71944628	Rat
10402859	Bp381	Blood pressure QTL 381		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	27606468	72606468	Rat
2292441	Bp308	Blood pressure QTL 308			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	27606468	72606468	Rat
724527	Bp148	Blood pressure QTL 148		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	28453136	73453136	Rat
1600371	Mcs21	Mammary carcinoma susceptibility QTL 21	3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	28875650	52200160	Rat
1331762	Rf40	Renal function QTL 40	3.873		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	10	29299504	64155584	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
631557	Bp136	Blood pressure QTL 136		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	30632053	75632053	Rat
1576311	Pia26	Pristane induced arthritis QTL 26			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	31224026	75632053	Rat
1578779	Tcas10	Tongue tumor susceptibility QTL 10	3.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	10	31297439	76297439	Rat
1576319	Cia29	Collagen induced arthritis QTL 29			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	33973921	78973921	Rat
61332	Eau3	Experimental allergic uveoretinitis QTL 3		0.004	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	34490559	45579777	Rat
1354614	Hpcl1	Hepatic cholesterol level QTL 1	3.3		liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	35392267	51793994	Rat
1358897	Stresp6	Stress response QTL 6	4.17	0.022	blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	35392267	64155584	Rat
61441	Btemp1	Thermal response to stress QTL 1	4		body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	10	35392457	63642539	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	10	74	35	41	11	8
Low								1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399428	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399429	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006246237	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006246238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767672	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085381	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085382	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085383	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063268583	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063268584	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063268585	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC141334	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC079006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000005048 ⟹ ENSRNOP00000005048

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	35,524,755 - 35,541,352 (+)	Ensembl
Rnor_6.0 Ensembl	10	36,715,565 - 36,733,133 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000119764 ⟹ ENSRNOP00000079861

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	35,528,096 - 35,541,279 (+)	Ensembl

RefSeq Acc Id:

NM_001013041 ⟹ NP_001013059

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	36,024,458 - 36,042,028 (+)	NCBI
mRatBN7.2	10	35,523,473 - 35,541,043 (+)	NCBI
Rnor_6.0	10	36,715,565 - 36,733,135 (+)	NCBI
Rnor_5.0	10	36,487,184 - 36,505,103 (+)	NCBI
RGSC_v3.4	10	36,782,792 - 36,800,362 (+)	RGD
Celera	10	34,879,664 - 34,897,233 (+)	RGD

Sequence:

show sequence

CTTGGAACATTTTCCTCTAACTAAGAAAAATGCGGCATTCCAAACGAACTCACTGTCCTGATTG
GGATAGCAGAGAAAGCTGGGGCCATGAAAGCTACAGTGGAAGTCACAAACGGAAGAGGAGATCT
CATAGCAGTACGCAGGAGAATAGGCATTGTAAACCACATCATCAGTTTAAAGACACTGATTGTC
ACTATTTAGAAGCAAGATGCTTGAATGAGAGAGATTATCGGGATCGGAGATACATTGATGAATA
CAGAAATGACTACTGTGAAGGATATGTTCCAAGACATTACCATAGAGACATTGAAAGCACTTAC
CGGATCCATTGCAGTAAATCCTCAGTCAGAAGCAGGAGAAGCAGCCCTAAAAGAAAACGTAACA
GACACTGTGCGAGTCATCAGTCACATTCGATGAAATCGTGGACACTTTAGGTGAAGGGGCCTTT
GGCAAAGTTGTAGAGTGCATTGATCATGGCATGGATGGCTTACATGTGGCAGTGAAAATTGTAA
AAAATGTAGGCCGTTACCGGGAGGCAGCTCGCTCTGAAATCCAAGTGCTGGAGCACTTGAACAG
CACTGACCCCAATAGTGTCTTCCGATGTGTCCAGATGCTAGAATGGTTTGATCATCATGGTCAT
GTTTGTATTGTGTTTGAGCTGCTGGGCCTTAGTACCTATGATTTTATTAAAGAAAACAGCTTTC
TGCCATTTCAAATTGATCACATCAGGCAAATGGCTTATCAGATCTGCCAATCTATAAATTTTTT
ACATCATAATAAATTAACACACACGGATCTAAAACCTGAAAATATTTTATTTGTAAAGTCTGAC
TATGTGGTCAAATACAATTCTAAAATGAAACGAGATGAGCGCACGTTGAAAAACACAGATATCA
AAGTTGTTGACTTTGGAAGTGCGACATATGACGATGAACATCATAGTACTTTGGTGTCCACAAG
ACACTACAGGGCTCCAGAGGTCATTTTGGCTTTAGGTTGGTCTCAGCCTTGTGATGTTTGGAGC
ATAGGCTGCATTCTTATTGAGTATTACCTTGGATTCACAGTCTTTCAGACTCATGATAGTAAAG
AACACCTGGCAATGATGGAGCGGATACTCGGGCCCATCCCAGCACACATGATCCAAAAGACAAG
GAAACGCAAGTATTTCCACCATAACCAGCTAGATTGGGATGAGCATAGTTCAGCTGGGAGATAC
GTTAGGAGACGCTGCAAGCCGTTAAAGGAATTTATGCTGTGTCACGATGAAGAGCATGAGAAGC
TGTTTGACCTGGTTCGAAGAATGTTGGAGTATGACCCAACAAAAAGGATTACCTTGGATGAAGC
TTTGCAGCACCCTTTCTTTGACTTATTAAAAGGGAAATGAATGGGAAAAAAAAAAAAAAAAAAA
AAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001399428 ⟹ NP_001386357

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	36,025,740 - 36,042,366 (+)	NCBI
mRatBN7.2	10	35,524,755 - 35,541,381 (+)	NCBI

RefSeq Acc Id:

NM_001399429 ⟹ NP_001386358

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	36,025,740 - 36,042,366 (+)	NCBI
mRatBN7.2	10	35,524,755 - 35,541,381 (+)	NCBI

RefSeq Acc Id:

XM_006246237 ⟹ XP_006246299

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	36,029,614 - 36,042,366 (+)	NCBI
mRatBN7.2	10	35,528,629 - 35,541,384 (+)	NCBI
Rnor_6.0	10	36,720,771 - 36,733,473 (+)	NCBI
Rnor_5.0	10	36,487,184 - 36,505,103 (+)	NCBI

Sequence:

show sequence

TGGAAGTCACAAACGGAAGAGGAGATCTCATAGCAGTACGCAGGAGAATAGGCATTGTAAACCA
CATCATCAGTTTAAAGACACTGATTGATGTTCCATTGGGGCTGTTTACCAGATTGCTTTCTAAA
TTAGCCAGCTGGGGTTACTTTAAAAACATGCTCCATGTGCATCCCTCTTGAAGCTTCGCACTCT
GTTGAAGAGGACACTCATCCCAGTCACTATTTAGAAGCAAGATGCTTGAATGAGAGAGATTATC
GGGATCGGAGATACATTGATGAATACAGAAATGACTACTGTGAAGGATATGTTCCAAGACATTA
CCATAGAGACATTGAAAGCACTTACCGGATCCATTGCAGTAAATCCTCAGTCAGAAGCAGGAGA
AGCAGCCCTAAAAGAAAACGTAACAGACACTGTGCGAGTCATCAGTCACATTCGAAGAGCCACC
GAAGGAAAAGATCCAGGAGTATAGAGGATGATGAGGAGGGTCACCTGATCTGTCAAAGTGGAGA
CGTTCTAAGAGCAAGATATGAAATCGTGGACACTTTAGGTGAAGGGGCCTTTGGCAAAGTTGTA
GAGTGCATTGATCATGGCATGGATGGCTTACATGTGGCAGTGAAAATTGTAAAAAATGTAGGCC
GTTACCGGGAGGCAGCTCGCTCTGAAATCCAAGTGCTGGAGCACTTGAACAGCACTGACCCCAA
TAGTGTCTTCCGATGTGTCCAGATGCTAGAATGGTTTGATCATCATGGTCATGTTTGTATTGTG
TTTGAGCTGCTGGGCCTTAGTACCTATGATTTTATTAAAGAAAACAGCTTTCTGCCATTTCAAA
TTGATCACATCAGGCAAATGGCTTATCAGATCTGCCAATCTATAAATTTTTTACATCATAATAA
ATTAACACACACGGATCTAAAACCTGAAAATATTTTATTTGTAAAGTCTGACTATGTGGTCAAA
TACAATTCTAAAATGAAACGAGATGAGCGCACGTTGAAAAACACAGATATCAAAGTTGTTGACT
TTGGAAGTGCGACATATGACGATGAACATCATAGTACTTTGGTGTCCACAAGACACTACAGGGC
TCCAGAGGTCATTTTGGCTTTAGGTTGGTCTCAGCCTTGTGATGTTTGGAGCATAGGCTGCATT
CTTATTGAGTATTACCTTGGATTCACAGTCTTTCAGACTCATGATAGTAAAGAACACCTGGCAA
TGATGGAGCGGATACTCGGGCCCATCCCAGCACACATGATCCAAAAGACAAGGAAACGCAAGTA
TTTCCACCATAACCAGCTAGATTGGGATGAGCATAGTTCAGCTGGGAGATACGTTAGGAGACGC
TGCAAGCCGTTAAAGGAATTTATGCTGTGTCACGATGAAGAGCATGAGAAGCTGTTTGACCTGG
TTCGAAGAATGTTGGAGTATGACCCAACAAAAAGGATTACCTTGGATGAAGCTTTGCAGCACCC
TTTCTTTGACTTATTAAAAGGGAAATGAATGGGAATCAGTGGTCTTCCTATATACTTCTCTAGG
AGCAATTACTTTAAGACTGTGTCAGTCAACTAAACATTCTAATATTTTTGTAAACATTAAATTA
TTTTGTACAGTTAAATGTAAATACTGTATGTTTTGTATCAATAGCATAACTACCTTGTTAAGTA
TGGTGTTGATAATGAATGCAATATGAGTTAAAATGGATTTTCCTTTGATGTTAATTGCCATTTT
TAAAGGCCTTTACAGTGCCCTTTGTGTCCAGTGGTAAACGTGATTGGTCTCATCTTTTGTACAT
TAAGGTTAACTCTGAAGTGTTTTTTTTTTCCCTCAAGTAAAAGGAAATCTTGA

hide sequence

RefSeq Acc Id:

XM_008767672 ⟹ XP_008765894

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	36,029,615 - 36,042,366 (+)	NCBI
mRatBN7.2	10	35,528,630 - 35,541,384 (+)	NCBI
Rnor_6.0	10	36,720,771 - 36,733,473 (+)	NCBI

Sequence:

show sequence

TGGAAGTCACAAACGGAAGAGGAGATCTCATAGCAGTACGCAGGAGAATAGGCATTGTAAACCA
CATCATCAGTTTAAAGACACTGATTGTGCTCCATGTGCATCCCTCTTGAAGCTTCGCACTCTGT
TGAAGAGGACACTCATCCCAGTCACTATTTAGAAGCAAGATGCTTGAATGAGAGAGATTATCGG
GATCGGAGATACATTGATGAATACAGAAATGACTACTGTGAAGGATATGTTCCAAGACATTACC
ATAGAGACATTGAAAGCACTTACCGGATCCATTGCAGTAAATCCTCAGTCAGAAGCAGGAGAAG
CAGCCCTAAAAGAAAACGTAACAGACACTGTGCGAGTCATCAGTCACATTCGAAGAGCCACCGA
AGGAAAAGATCCAGGAGTATAGAGGATGATGAGGAGGGTCACCTGATCTGTCAAAGTGGAGACG
TTCTAAGAGCAAGATATGAAATCGTGGACACTTTAGGTGAAGGGGCCTTTGGCAAAGTTGTAGA
GTGCATTGATCATGGCATGGATGGCTTACATGTGGCAGTGAAAATTGTAAAAAATGTAGGCCGT
TACCGGGAGGCAGCTCGCTCTGAAATCCAAGTGCTGGAGCACTTGAACAGCACTGACCCCAATA
GTGTCTTCCGATGTGTCCAGATGCTAGAATGGTTTGATCATCATGGTCATGTTTGTATTGTGTT
TGAGCTGCTGGGCCTTAGTACCTATGATTTTATTAAAGAAAACAGCTTTCTGCCATTTCAAATT
GATCACATCAGGCAAATGGCTTATCAGATCTGCCAATCTATAAATTTTTTACATCATAATAAAT
TAACACACACGGATCTAAAACCTGAAAATATTTTATTTGTAAAGTCTGACTATGTGGTCAAATA
CAATTCTAAAATGAAACGAGATGAGCGCACGTTGAAAAACACAGATATCAAAGTTGTTGACTTT
GGAAGTGCGACATATGACGATGAACATCATAGTACTTTGGTGTCCACAAGACACTACAGGGCTC
CAGAGGTCATTTTGGCTTTAGGTTGGTCTCAGCCTTGTGATGTTTGGAGCATAGGCTGCATTCT
TATTGAGTATTACCTTGGATTCACAGTCTTTCAGACTCATGATAGTAAAGAACACCTGGCAATG
ATGGAGCGGATACTCGGGCCCATCCCAGCACACATGATCCAAAAGACAAGGAAACGCAAGTATT
TCCACCATAACCAGCTAGATTGGGATGAGCATAGTTCAGCTGGGAGATACGTTAGGAGACGCTG
CAAGCCGTTAAAGGAATTTATGCTGTGTCACGATGAAGAGCATGAGAAGCTGTTTGACCTGGTT
CGAAGAATGTTGGAGTATGACCCAACAAAAAGGATTACCTTGGATGAAGCTTTGCAGCACCCTT
TCTTTGACTTATTAAAAGGGAAATGAATGGGAATCAGTGGTCTTCCTATATACTTCTCTAGGAG
CAATTACTTTAAGACTGTGTCAGTCAACTAAACATTCTAATATTTTTGTAAACATTAAATTATT
TTGTACAGTTAAATGTAAATACTGTATGTTTTGTATCAATAGCATAACTACCTTGTTAAGTATG
GTGTTGATAATGAATGCAATATGAGTTAAAATGGATTTTCCTTTGATGTTAATTGCCATTTTTA
AAGGCCTTTACAGTGCCCTTTGTGTCCAGTGGTAAACGTGATTGGTCTCATCTTTTGTACATTA
AGGTTAACTCTGAAGTGTTTTTTTTTTCCCTCAAGTAAAAGGAAATCTTGA

hide sequence

RefSeq Acc Id:

XM_039085381 ⟹ XP_038941309

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	36,025,667 - 36,042,366 (+)	NCBI
mRatBN7.2	10	35,524,702 - 35,541,384 (+)	NCBI

RefSeq Acc Id:

XM_039085382 ⟹ XP_038941310

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	36,024,378 - 36,042,366 (+)	NCBI
mRatBN7.2	10	35,523,382 - 35,541,384 (+)	NCBI

RefSeq Acc Id:

XM_039085383 ⟹ XP_038941311

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	36,029,614 - 36,042,366 (+)	NCBI
mRatBN7.2	10	35,523,457 - 35,541,384 (+)	NCBI

RefSeq Acc Id:

XM_063268583 ⟹ XP_063124653

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	36,024,364 - 36,042,366 (+)	NCBI

RefSeq Acc Id:

XM_063268584 ⟹ XP_063124654

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	36,029,614 - 36,042,366 (+)	NCBI

RefSeq Acc Id:

XM_063268585 ⟹ XP_063124655

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	36,025,708 - 36,042,366 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001013059	(Get FASTA)	NCBI Sequence Viewer
	NP_001386357	(Get FASTA)	NCBI Sequence Viewer
	NP_001386358	(Get FASTA)	NCBI Sequence Viewer
	XP_006246299	(Get FASTA)	NCBI Sequence Viewer
	XP_008765894	(Get FASTA)	NCBI Sequence Viewer
	XP_038941309	(Get FASTA)	NCBI Sequence Viewer
	XP_038941310	(Get FASTA)	NCBI Sequence Viewer
	XP_038941311	(Get FASTA)	NCBI Sequence Viewer
	XP_063124653	(Get FASTA)	NCBI Sequence Viewer
	XP_063124654	(Get FASTA)	NCBI Sequence Viewer
	XP_063124655	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79006	(Get FASTA)	NCBI Sequence Viewer
	EDM04303	(Get FASTA)	NCBI Sequence Viewer
	EDM04304	(Get FASTA)	NCBI Sequence Viewer
	EDM04305	(Get FASTA)	NCBI Sequence Viewer
	EDM04306	(Get FASTA)	NCBI Sequence Viewer
	EDM04307	(Get FASTA)	NCBI Sequence Viewer
	EDM04308	(Get FASTA)	NCBI Sequence Viewer
	EDM04309	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000005048
	ENSRNOP00000005048.6
	ENSRNOP00000079861
	ENSRNOP00000079861.1

RefSeq Acc Id:	NP_001013059 ⟸ NM_001013041
- Peptide Label:	isoform 3
- UniProtKB:	Q6AYK7 (UniProtKB/TrEMBL), A6HE53 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDGLHVAVKIVKNVGRYREAARSEIQVLEHLNSTDPNSVFRCVQMLEWFDHHGHVCIVFELLGL STYDFIKENSFLPFQIDHIRQMAYQICQSINFLHHNKLTHTDLKPENILFVKSDYVVKYNSKMK RDERTLKNTDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYL GFTVFQTHDSKEHLAMMERILGPIPAHMIQKTRKRKYFHHNQLDWDEHSSAGRYVRRRCKPLKE FMLCHDEEHEKLFDLVRRMLEYDPTKRITLDEALQHPFFDLLKGK hide sequence

RefSeq Acc Id:	XP_006246299 ⟸ XM_006246237
- Peptide Label:	isoform X3
- UniProtKB:	F7ETQ4 (UniProtKB/TrEMBL), A6HE49 (UniProtKB/TrEMBL)
- Sequence:	show sequence MCIPLEASHSVEEDTHPSHYLEARCLNERDYRDRRYIDEYRNDYCEGYVPRHYHRDIESTYRIH CSKSSVRSRRSSPKRKRNRHCASHQSHSKSHRRKRSRSIEDDEEGHLICQSGDVLRARYEIVDT LGEGAFGKVVECIDHGMDGLHVAVKIVKNVGRYREAARSEIQVLEHLNSTDPNSVFRCVQMLEW FDHHGHVCIVFELLGLSTYDFIKENSFLPFQIDHIRQMAYQICQSINFLHHNKLTHTDLKPENI LFVKSDYVVKYNSKMKRDERTLKNTDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQ PCDVWSIGCILIEYYLGFTVFQTHDSKEHLAMMERILGPIPAHMIQKTRKRKYFHHNQLDWDEH SSAGRYVRRRCKPLKEFMLCHDEEHEKLFDLVRRMLEYDPTKRITLDEALQHPFFDLLKGK hide sequence

RefSeq Acc Id:	XP_008765894 ⟸ XM_008767672
- Peptide Label:	isoform X3
- UniProtKB:	F7ETQ4 (UniProtKB/TrEMBL), A6HE49 (UniProtKB/TrEMBL)
- Sequence:	show sequence MCIPLEASHSVEEDTHPSHYLEARCLNERDYRDRRYIDEYRNDYCEGYVPRHYHRDIESTYRIH CSKSSVRSRRSSPKRKRNRHCASHQSHSKSHRRKRSRSIEDDEEGHLICQSGDVLRARYEIVDT LGEGAFGKVVECIDHGMDGLHVAVKIVKNVGRYREAARSEIQVLEHLNSTDPNSVFRCVQMLEW FDHHGHVCIVFELLGLSTYDFIKENSFLPFQIDHIRQMAYQICQSINFLHHNKLTHTDLKPENI LFVKSDYVVKYNSKMKRDERTLKNTDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQ PCDVWSIGCILIEYYLGFTVFQTHDSKEHLAMMERILGPIPAHMIQKTRKRKYFHHNQLDWDEH SSAGRYVRRRCKPLKEFMLCHDEEHEKLFDLVRRMLEYDPTKRITLDEALQHPFFDLLKGK hide sequence

RefSeq Acc Id:

ENSRNOP00000005048 ⟸ ENSRNOT00000005048

RefSeq Acc Id:	XP_038941310 ⟸ XM_039085382
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038941311 ⟸ XM_039085383
- Peptide Label:	isoform X4
- UniProtKB:	Q6AYK7 (UniProtKB/TrEMBL), A6HE53 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038941309 ⟸ XM_039085381
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSRNOP00000079861 ⟸ ENSRNOT00000119764

RefSeq Acc Id:	NP_001386358 ⟸ NM_001399429
- Peptide Label:	isoform 2
- UniProtKB:	F7ETQ4 (UniProtKB/TrEMBL), A6HE49 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386357 ⟸ NM_001399428
- Peptide Label:	isoform 1
- UniProtKB:	A0A8I5ZNT1 (UniProtKB/TrEMBL), A6HE48 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063124653 ⟸ XM_063268583
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZNT1 (UniProtKB/TrEMBL), A6HE48 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063124655 ⟸ XM_063268585
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_063124654 ⟸ XM_063268584
- Peptide Label:	isoform X4
- UniProtKB:	Q6AYK7 (UniProtKB/TrEMBL)

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AYK7-F1-model_v2	AlphaFold	Q6AYK7	1-301	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697159

Promoter ID:

EPDNEW_R7683

Type:

single initiation site

Name:

Clk4_1

Description:

CDC-like kinase 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	36,715,533 - 36,715,593	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310274	AgrOrtholog
BioCyc Gene	G2FUF-25203	BioCyc
Ensembl Genes	ENSRNOG00000003714	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000005048	ENTREZGENE
	ENSRNOT00000005048.6	UniProtKB/TrEMBL
	ENSRNOT00000119764	ENTREZGENE
	ENSRNOT00000119764.1	UniProtKB/TrEMBL
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7113075	IMAGE-MGC_LOAD
InterPro	Kinase-like_dom	UniProtKB/TrEMBL
	Prot_kinase_cat_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
KEGG Report	rno:287269	UniProtKB/TrEMBL
MGC_CLONE	MGC:93919	IMAGE-MGC_LOAD
NCBI Gene	287269	ENTREZGENE
PANTHER	DUAL SPECIFICITY PROTEIN KINASE CLK4	UniProtKB/TrEMBL
	SERINE/THREONINE-PROTEIN KINASE DOA-RELATED	UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/TrEMBL
PhenoGen	Clk4	PhenoGen
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000003714	RatGTEx
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	Kinase_like	UniProtKB/TrEMBL
UniProt	A0A8I5ZNT1	ENTREZGENE, UniProtKB/TrEMBL
	A6HE48	ENTREZGENE, UniProtKB/TrEMBL
	A6HE49	ENTREZGENE, UniProtKB/TrEMBL
	A6HE53	ENTREZGENE, UniProtKB/TrEMBL
	A6HE54_RAT	UniProtKB/TrEMBL
	F7ETQ4	ENTREZGENE, UniProtKB/TrEMBL
	Q6AYK7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-07-13	Clk4	CDC-like kinase 4	Clk4	CDC like kinase 4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Clk4	CDC like kinase 4	Clk4_predicted	CDC like kinase 4 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Clk4_predicted	CDC like kinase 4 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar