Symbol:
Trim40
Name:
tripartite motif-containing 40
RGD ID:
1359645
Description:
Predicted to enable ubiquitin protein ligase activity. Involved in negative regulation of NF-kappaB transcription factor activity and negative regulation of cell growth. Predicted to be part of IkappaB kinase complex. Predicted to be active in cytoplasm. Orthologous to human TRIM40 (tripartite motif containing 40); INTERACTS WITH bisphenol A; linsidomine; 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
E3 ubiquitin ligase TRIM40; probable E3 NEDD8-protein ligase; RING finger protein 35; Rnf35; tripartite motif protein 40; tripartite motif-containing protein 40; tripartite motif-containing protein 40-like
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 20 1,680,554 - 1,691,123 (+) NCBI GRCr8 mRatBN7.2 20 1,676,114 - 1,685,906 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 20 1,676,270 - 1,685,214 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 20 1,729,830 - 1,738,396 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 20 1,733,332 - 1,741,894 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 20 1,673,911 - 1,682,490 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 20 2,169,674 - 2,178,477 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 20 2,169,545 - 2,178,601 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 20 4,205,817 - 4,216,051 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 20 1,768,482 - 1,777,393 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 20 1,768,481 - 1,777,393 (+) NCBI Celera 20 2,385,041 - 2,394,038 (+) NCBI Celera Cytogenetic Map 20 p12 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Trim40 (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 20 1,680,554 - 1,691,123 (+) NCBI GRCr8 mRatBN7.2 20 1,676,114 - 1,685,906 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 20 1,676,270 - 1,685,214 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 20 1,729,830 - 1,738,396 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 20 1,733,332 - 1,741,894 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 20 1,673,911 - 1,682,490 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 20 2,169,674 - 2,178,477 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 20 2,169,545 - 2,178,601 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 20 4,205,817 - 4,216,051 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 20 1,768,482 - 1,777,393 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 20 1,768,481 - 1,777,393 (+) NCBI Celera 20 2,385,041 - 2,394,038 (+) NCBI Celera Cytogenetic Map 20 p12 NCBI
TRIM40 (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 6 30,136,140 - 30,148,735 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 6 30,136,124 - 30,148,735 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 6 30,103,917 - 30,116,512 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 6 30,212,489 - 30,224,488 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 6 30,212,488 - 30,223,570 NCBI Celera 6 31,702,776 - 31,714,781 (+) NCBI Celera Cytogenetic Map 6 p22.1 NCBI HuRef 6 29,902,691 - 29,914,687 (+) NCBI HuRef CHM1_1 6 30,106,586 - 30,118,587 (+) NCBI CHM1_1 T2T-CHM13v2.0 6 30,000,415 - 30,013,010 (+) NCBI T2T-CHM13v2.0
Trim40 (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 17 37,192,488 - 37,201,049 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 17 37,192,490 - 37,201,015 (-) Ensembl GRCm39 Ensembl GRCm38 17 36,881,596 - 36,890,157 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 17 36,881,598 - 36,890,123 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 17 37,018,543 - 37,027,070 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 17 36,489,651 - 36,498,098 (-) NCBI MGSCv36 mm8 Celera 17 40,300,820 - 40,309,325 (-) NCBI Celera Cytogenetic Map 17 B1 NCBI cM Map 17 19.16 NCBI
Trim40 (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955583 242,054 - 259,008 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955583 242,054 - 260,565 (+) NCBI ChiLan1.0 ChiLan1.0
TRIM40 (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 5 44,720,791 - 44,744,925 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 6 40,683,795 - 40,704,421 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 6 29,912,857 - 29,926,550 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 6 30,583,968 - 30,596,583 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 6 30,584,272 - 30,599,635 (+) Ensembl panpan1.1 panPan2
Trim40 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
TRIM40 (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 7 22,702,925 - 22,717,511 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 7 22,702,891 - 22,717,850 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 7 24,860,690 - 24,873,040 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
TRIM40 (Chlorocebus sabaeus - green monkey)
Trim40 (Heterocephalus glaber - naked mole-rat)
.
Predicted Target Of
Count of predictions: 108 Count of miRNA genes: 91 Interacting mature miRNAs: 94 Transcripts: ENSRNOT00000029070 Prediction methods: Microtar, Rnahybrid, Targetscan Result types: miRGate_prediction
2306850 Pia40 Pristane induced arthritis QTL 40 0.0001 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 20 1527959 5304575 Rat 1641915 Colcr9 Colorectal carcinoma resistance QTL 9 2.97 0.0024 intestine integrity trait (VT:0010554) benign colorectal tumor number (CMO:0001795) 20 1530655 46530655 Rat 7387283 Uae44 Urinary albumin excretion QTL 44 0.1712 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 20 1 26123605 Rat 7411668 Foco32 Food consumption QTL 32 8 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 20 1 36600972 Rat 2305926 Iddm37 Insulin dependent diabetes mellitus QTL 37 6 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 20 1527842 46527842 Rat 1354642 Despr15 Despair related QTL 15 0.0027 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 20 1 24159021 Rat 1600382 Edcs3 Endometrial carcinoma susceptibility QTL3 3.5 0.003 uterus morphology trait (VT:0001120) percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759) 20 1 25159026 Rat 8694189 Bw153 Body weight QTL 153 3.13 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 20 1 29191651 Rat 724519 Bp144 Blood pressure QTL 144 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 20 1 3624629 Rat 9590109 Sffal8 Serum free fatty acids level QTL 8 5.32 0.01 blood free fatty acid amount (VT:0001553) plasma free fatty acids level (CMO:0000546) 20 1 29191651 Rat 9590275 Scort15 Serum corticosterone level QTL 15 3.48 0.001 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 20 1 29191651 Rat 9589155 Insul32 Insulin level QTL 32 6.38 0.001 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 20 1 29191651 Rat 7411650 Foco23 Food consumption QTL 23 20.7 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 20 1 29191651 Rat 2317851 Alcrsp22 Alcohol response QTL 22 3.2 0.05 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 20 1 27339237 Rat 1641893 Alcrsp7 Alcohol response QTL 7 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 20 1 27339237 Rat 6893685 Bw111 Body weight QTL 111 2.7 0.004 body mass (VT:0001259) body weight (CMO:0000012) 20 1 32578807 Rat 9590252 Scort12 Serum corticosterone level QTL 12 20.46 0.001 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 20 1 36600972 Rat
D20Yum3
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 20 1,679,261 - 1,679,465 (+) MAPPER mRatBN7.2 Rnor_6.0 20 2,172,537 - 2,172,740 NCBI Rnor6.0 Rnor_5.0 20 4,209,526 - 4,209,729 UniSTS Rnor5.0 RGSC_v3.4 20 1,771,345 - 1,771,548 UniSTS RGSC3.4 Celera 20 2,387,904 - 2,388,107 UniSTS Cytogenetic Map 20 p12 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
3
17
16
11
7
11
28
8
2
14
5
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000029070 ⟹ ENSRNOP00000035419
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 20 1,676,270 - 1,685,214 (+) Ensembl Rnor_6.0 Ensembl 20 2,169,545 - 2,178,601 (+) Ensembl
RefSeq Acc Id:
NM_001009175 ⟹ NP_001009175
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 20 1,681,333 - 1,691,123 (+) NCBI mRatBN7.2 20 1,676,114 - 1,685,906 (+) NCBI Rnor_6.0 20 2,169,674 - 2,178,469 (+) NCBI Rnor_5.0 20 4,205,817 - 4,216,051 (+) NCBI RGSC_v3.4 20 1,768,482 - 1,777,393 (+) RGD Celera 20 2,385,041 - 2,394,038 (+) NCBI
Sequence:
ATGGTCCCTCTTGACAAGGACAACCAGGACATTTGTCCTATCTGCCTGGATCCCCTGAAGGAGGCTGTGAGCACCGACTGCAGACACCTTTTCTGCCGCATGTGCCTGATCCGGCACATGGATAAGGC TTCGGTCTCCGGGGTTCTCAGCTGCCCGGTCTGCAGGAAGCCCTGTTCGGAGACAGTCCTTGGAGACAATTACATCTGCCACACTCACCAGAAGAGGGTGTGCAGGTTCTGTGAGTCTAGCAGACACC TCCTGTGTGAGGAATGCCTCCAGTCCCCCGAACACCGGGCCCATACTGAGCTCTCCATTGAAAATGCCATCAGCCACTACAAGGAAAGACTCAATCGGAGAAGCAGGAAGCTCAGAAAGGACCTTGGG GACCTTCAACGGCTGAAGGCTCAGGAAGAGAAGATGCTCCAGGCTCTGCAGGTTGATTGGGGGAGCCACAGGCCAAGAACTGAGCAGCAGAACCAAGACCAAACCGAGCTACAGCAGAAGGCCCTCCC TCGGCATTGGCTGGACCAACGAGAGGACCCGCCAGAGGAGGTGGCCAAGGTCTTTAACTTCTCTGAGGCAGTAACACAGCTCAGCATCCTGGTTTCCAGTCTGGAAAGGATGGCCAAGGAACTGGACG CCAGCACCCTGAAGGATGCCAGCGACTTACTGGACAGGAGTTCGCAACAGAAACTAGAAGGACTTCTCTCTCATGTTCCTCCAGCCAACTCTAAGCTCAGTTAG
hide sequence
RefSeq Acc Id:
XM_063279326 ⟹ XP_063135396
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 20 1,680,554 - 1,691,123 (+) NCBI
RefSeq Acc Id:
XM_063279327 ⟹ XP_063135397
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 20 1,680,554 - 1,691,123 (+) NCBI
RefSeq Acc Id:
NP_001009175 ⟸ NM_001009175
- UniProtKB:
Q6MFY8 (UniProtKB/Swiss-Prot)
- Sequence:
MVPLDKDNQDICPICLDPLKEAVSTDCRHLFCRMCLIRHMDKASVSGVLSCPVCRKPCSETVLGDNYICHTHQKRVCRFCESSRHLLCEECLQSPEHRAHTELSIENAISHYKERLNRRSRKLRKDLG DLQRLKAQEEKMLQALQVDWGSHRPRTEQQNQDQTELQQKALPRHWLDQREDPPEEVAKVFNFSEAVTQLSILVSSLERMAKELDASTLKDASDLLDRSSQQKLEGLLSHVPPANSKLS
hide sequence
Ensembl Acc Id:
ENSRNOP00000035419 ⟸ ENSRNOT00000029070
RefSeq Acc Id:
XP_063135396 ⟸ XM_063279326
- Peptide Label:
isoform X1
RefSeq Acc Id:
XP_063135397 ⟸ XM_063279327
- Peptide Label:
isoform X2
- UniProtKB:
Q6MFY8 (UniProtKB/Swiss-Prot)
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2013-05-24
Trim40
tripartite motif-containing 40
LOC100364386
tripartite motif-containing protein 40-like
Data merged from RGD:2321173
1643240
APPROVED
2010-05-05
LOC100364386
tripartite motif-containing protein 40-like
Symbol and Name status set to provisional
70820
PROVISIONAL
2008-03-07
Trim40
tripartite motif-containing 40
Trim40
tripartite motif protein 40
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2006-03-30
Trim40
tripartite motif protein 40
tripartite motif-containing 40
Name updated
1299863
APPROVED
2005-12-06
Trim40
tripartite motif-containing 40
Symbol and Name updated
1559027
APPROVED
2005-11-17
Trim40
tripartite motif-containing 40
Symbol and Name status set to approved
1299863
APPROVED
2005-07-29
Trim40
tripartite motif-containing 40
Symbol and Name status set to provisional
70820
PROVISIONAL