Myo5c (myosin VC) - Rat Genome Database

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Gene: Myo5c (myosin VC) Rattus norvegicus
Analyze
Symbol: Myo5c
Name: myosin VC
RGD ID: 1309994
Description: Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization and endocytosis. Predicted to be part of myosin complex. Predicted to be active in actin cytoskeleton; cytoplasm; and membrane. Orthologous to human MYO5C (myosin VC); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC315820; myosin-Vc; unconventional myosin-Vc
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8884,870,031 - 84,946,996 (+)NCBIGRCr8
mRatBN7.2875,989,497 - 76,066,485 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl875,989,528 - 76,066,483 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx881,496,835 - 81,574,055 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0879,761,746 - 79,838,757 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0877,596,161 - 77,673,391 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0882,171,296 - 82,248,109 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl882,171,497 - 82,247,544 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0881,771,484 - 81,851,384 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4880,101,971 - 80,119,034 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1880,057,940 - 80,136,830 (+)NCBI
Celera875,779,366 - 75,856,253 (+)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myo5cRatBloom syndrome  ISORGD:13206408554872ClinVar Annotator: match by term: Bloom syndromeClinVarPMID:28492532
Myo5cRatcolorectal cancer  ISORGD:13206408554872ClinVar Annotator: match by term: Familial colorectal cancerClinVarPMID:28492532
Myo5cRatparaplegia  ISORGD:13206408554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:21620353|PMID:21937992|PMID:23472171|PMID:28492532|PMID:30237576|PMID:30732576|PMID:31688942
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myo5cRatsubstance-related disorder  ISORGD:132064011554173CTD Direct Evidence: marker/mechanismCTDPMID:20098672

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Object Symbol
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Term
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Reference
Notes
Source
Original Reference(s)
Myo5cRat(+)-catechin multiple interactionsISORGD:13206406480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of MYO5C mRNACTDPMID:24763279
Myo5cRat1,2-dichloroethane decreases expressionISORGD:15514076480464ethylene dichloride results in decreased expression of MYO5C mRNACTDPMID:28960355
Myo5cRat1,2-dimethylhydrazine decreases expressionISORGD:155140764804641,2-Dimethylhydrazine results in decreased expression of MYO5C mRNACTDPMID:22206623
Myo5cRat17beta-estradiol multiple interactionsISORGD:13206406480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of MYO5C mRNACTDPMID:30165855
Myo5cRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORGD:13206406480464Tetrachlorodibenzodioxin results in decreased expression of MYO5C mRNACTDPMID:21632981
Myo5cRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORGD:15514076480464Tetrachlorodibenzodioxin results in decreased expression of MYO5C mRNACTDPMID:33956508
Myo5cRat3-Nitrobenzanthrone decreases expressionISORGD:132064064804643-nitrobenzanthrone results in decreased expression of MYO5C mRNACTDPMID:34036453
Myo5cRat4,4'-sulfonyldiphenol increases expressionISORGD:15514076480464bisphenol S results in increased expression of MYO5C mRNACTDPMID:30951980
Myo5cRat4,4'-sulfonyldiphenol affects methylationISORGD:15514076480464bisphenol S affects the methylation of MYO5C geneCTDPMID:31683443
Myo5cRat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of MYO5C mRNACTDPMID:30047161
Myo5cRatacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of MYO5C mRNACTDPMID:28959563
Myo5cRataflatoxin B1 increases methylationISORGD:13206406480464Aflatoxin B1 results in increased methylation of MYO5C exonCTDPMID:30157460
Myo5cRatall-trans-retinoic acid decreases expressionISORGD:13206406480464Tretinoin results in decreased expression of MYO5C mRNACTDPMID:23724009
Myo5cRatamitrole increases expressionEXP 6480464Amitrole results in increased expression of MYO5C mRNACTDPMID:30047161
Myo5cRatantirheumatic drug increases expressionISORGD:13206406480464Antirheumatic Agents results in increased expression of MYO5C mRNACTDPMID:24449571
Myo5cRatarsane affects methylationISORGD:13206406480464Arsenic affects the methylation of MYO5C geneCTDPMID:25304211
Myo5cRatarsane multiple interactionsISORGD:13206406480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...CTDPMID:39836092
Myo5cRatarsenic atom affects methylationISORGD:13206406480464Arsenic affects the methylation of MYO5C geneCTDPMID:25304211
Myo5cRatarsenic atom multiple interactionsISORGD:13206406480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...CTDPMID:39836092
Myo5cRatarsenite(3-) multiple interactionsISORGD:13206406480464arsenite inhibits the reaction [G3BP1 protein binds to MYO5C mRNA]CTDPMID:32406909

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Biological Process

  
Object Symbol
Species
Term
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Reference
Notes
Source
Original Reference(s)
Myo5cRatactin filament organization involved_inIBAFB:FBgn0000317|FB:FBgn0011225|PANTHER:PTN000320364|PomBase:SPBC2D10.14c|PomBase:SPCC1919.10c|RGD:70994|TAIR:locus:2025535|TAIR:locus:2199449|UniProtKB:O43795|dictyBase:DDB_G0275447|dictyBase:DDB_G0276363|dictyBase:DDB_G0288679|dictyBase:DDB_G02891771600115GO_REF:0000033GO_CentralGO_REF:0000033
Myo5cRatestablishment of protein localization involved_inIEAARBA:ARBA000271101600115GO_REF:0000117UniProtGO_REF:0000117
Myo5cRatprotein transport involved_inIEAUniProtKB-KW:KW-06531600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Myo5cRatactin cytoskeleton is_active_inIBACGD:CAL0000199209|FB:FBgn0000317|FB:FBgn0011225|FB:FBgn0040299|FB:FBgn0261397|MGI:104785|MGI:105976|MGI:107711|PANTHER:PTN000320364|PomBase:SPBC146.13c|PomBase:SPBC2D10.14c|PomBase:SPCC1919.10c|RGD:3135|RGD:3143|RGD:3144|RGD:621321|RGD:621347|RGD:628830|SGD:S000000027|SGD:S000004715|SGD:S000005853|UniProtKB:O00159|UniProtKB:O43795|UniProtKB:P47807|UniProtKB:Q00647|UniProtKB:Q02440|UniProtKB:Q29122|UniProtKB:Q8IDR3|UniProtKB:Q9I8D1|UniProtKB:Q9UBC5|UniProtKB:Q9UM54|UniProtKB:Q9Y4I1|dictyBase:DDB_G0272112|dictyBase:DDB_G0275447|dictyBase:DDB_G0276617|dictyBase:DDB_G0280039|dictyBase:DDB_G0288679|dictyBase:DDB_G0289117|dictyBase:DDB_G02891771600115GO_REF:0000033GO_CentralGO_REF:0000033
Myo5cRatcytoplasm is_active_inIBACGD:CAL0000199209|FB:FBgn0000317|FB:FBgn0010246|FB:FBgn0011225|FB:FBgn0086347|FB:FBgn0262029|MGI:104510|MGI:104785|MGI:105976|MGI:106612|MGI:106621|MGI:107709|MGI:107711|PANTHER:PTN000320364|PomBase:SPBC146.13c|PomBase:SPBC2D10.14c|PomBase:SPCC1919.10c|RGD:1560646|RGD:3143|RGD:3144|RGD:621321|RGD:621347|RGD:70994|SGD:S000004715|SGD:S000005853|TAIR:locus:2095370|TAIR:locus:2149529|TAIR:locus:2149932|UniProtKB:F1PRN2|UniProtKB:O00159|UniProtKB:O00160|UniProtKB:O43795|UniProtKB:P47807|UniProtKB:Q00647|UniProtKB:Q12965|UniProtKB:Q13402|UniProtKB:Q29122|UniProtKB:Q8IDR3|UniProtKB:Q96H55|UniProtKB:Q9I8D1|UniProtKB:Q9UBC5|UniProtKB:Q9ULV0|UniProtKB:Q9UM54|UniProtKB:Q9Y4I1|dictyBase:DDB_G0272112|dictyBase:DDB_G0274455|dictyBase:DDB_G0274575|dictyBase:DDB_G0275447|dictyBase:DDB_G0276617|dictyBase:DDB_G0280039|dictyBase:DDB_G0288679|dictyBase:DDB_G0289117|dictyBase:DDB_G02891771600115GO_REF:0000033GO_CentralGO_REF:0000033
Myo5cRatmembrane is_active_inIBAFB:FBgn0262029|MGI:104510|MGI:104785|MGI:106612|MGI:107732|MGI:1927091|PANTHER:PTN000320364|PomBase:SPBC146.13c|RGD:1560646|RGD:620443|RGD:621321|RGD:621347|RGD:70994|SGD:S000005853|TAIR:locus:2095370|TAIR:locus:2125929|UniProtKB:B0I1T2|UniProtKB:O00159|UniProtKB:O43795|UniProtKB:P47807|UniProtKB:Q13402|UniProtKB:Q8IDR3|UniProtKB:Q96H55|UniProtKB:Q9I8D1|UniProtKB:Q9UBC5|UniProtKB:Q9UM54|UniProtKB:Q9Y4I1|dictyBase:DDB_G0272112|dictyBase:DDB_G0274455|dictyBase:DDB_G0274575|dictyBase:DDB_G0275447|dictyBase:DDB_G0276617|dictyBase:DDB_G0280039|dictyBase:DDB_G0288679|dictyBase:DDB_G0289117|dictyBase:DDB_G02891771600115GO_REF:0000033GO_CentralGO_REF:0000033
Myo5cRatmyosin complex part_ofIEAUniProtKB-KW:KW-05181600115GO_REF:0000043UniProtGO_REF:0000043
Myo5cRatmyosin complex part_ofIEAInterPro:IPR001609|InterPro:IPR0040091600115GO_REF:0000002InterProGO_REF:0000002

Molecular Function
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Object Symbol
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Term
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Evidence
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Reference
Notes
Source
Original Reference(s)
Myo5cRatactin binding enablesIEAUniProtKB-KW:KW-00091600115GO_REF:0000043UniProtGO_REF:0000043
Myo5cRatactin filament binding enablesIBAFB:FBgn0011225|FB:FBgn0262029|MGI:107732|PANTHER:PTN000320364|PomBase:SPBC146.13c|RGD:620443|RGD:621321|RGD:70994|SGD:S000000027|SGD:S000005853|UniProtKB:O43795|UniProtKB:Q12965|UniProtKB:Q13402|UniProtKB:Q29122|UniProtKB:Q9UM54|dictyBase:DDB_G0272112|dictyBase:DDB_G0274455|dictyBase:DDB_G0274575|dictyBase:DDB_G0275447|dictyBase:DDB_G0276617|dictyBase:DDB_G0289117|dictyBase:DDB_G02922621600115GO_REF:0000033GO_CentralGO_REF:0000033
Myo5cRatATP binding enablesIEAUniRule:UR0006864691600115GO_REF:0000104UniProtGO_REF:0000104
Myo5cRatATP binding enablesIEAInterPro:IPR001609|InterPro:IPR0040091600115GO_REF:0000002InterProGO_REF:0000002
Myo5cRatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Myo5cRatcytoskeletal motor activity enablesIEAUniRule:UR0006864691600115GO_REF:0000104UniProtGO_REF:0000104
Myo5cRatcytoskeletal motor activity enablesIEAInterPro:IPR001609|InterPro:IPR0040091600115GO_REF:0000002InterProGO_REF:0000002
Myo5cRatmicrofilament motor activity enablesIBAFB:FBgn0000317|FB:FBgn0040299|FB:FBgn0086347|FB:FBgn0261397|MGI:105976|MGI:106612|MGI:1913446|PANTHER:PTN000320364|PomBase:SPBC146.13c|PomBase:SPBC2D10.14c|PomBase:SPCC1919.10c|RGD:3143|RGD:620443|RGD:621321|RGD:628830|RGD:70994|SGD:S000000027|SGD:S000004715|SGD:S000005853|TAIR:locus:2025535|TAIR:locus:2199449|UniProtKB:O43795|UniProtKB:P47807|UniProtKB:Q02440|UniProtKB:Q13402|UniProtKB:Q9I8D1|dictyBase:DDB_G0272112|dictyBase:DDB_G0275447|dictyBase:DDB_G0280039|dictyBase:DDB_G0288679|dictyBase:DDB_G0289117|dictyBase:DDB_G02922621600115GO_REF:0000033GO_CentralGO_REF:0000033
Myo5cRatnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8889548   PMID:23533145  



Myo5c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8884,870,031 - 84,946,996 (+)NCBIGRCr8
mRatBN7.2875,989,497 - 76,066,485 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl875,989,528 - 76,066,483 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx881,496,835 - 81,574,055 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0879,761,746 - 79,838,757 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0877,596,161 - 77,673,391 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0882,171,296 - 82,248,109 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl882,171,497 - 82,247,544 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0881,771,484 - 81,851,384 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4880,101,971 - 80,119,034 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1880,057,940 - 80,136,830 (+)NCBI
Celera875,779,366 - 75,856,253 (+)NCBICelera
Cytogenetic Map8q24NCBI
MYO5C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381552,192,322 - 52,295,804 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1552,192,322 - 52,295,804 (-)EnsemblGRCh38hg38GRCh38
GRCh371552,484,519 - 52,588,001 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361550,271,811 - 50,375,262 (-)NCBINCBI36Build 36hg18NCBI36
Build 341550,271,811 - 50,375,144NCBI
Celera1529,378,960 - 29,483,015 (-)NCBICelera
Cytogenetic Map15q21.2NCBI
HuRef1529,315,479 - 29,418,640 (-)NCBIHuRef
CHM1_11552,602,819 - 52,705,954 (-)NCBICHM1_1
T2T-CHM13v2.01550,000,957 - 50,104,091 (-)NCBIT2T-CHM13v2.0
Myo5c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39975,139,252 - 75,212,733 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl975,139,302 - 75,212,733 (+)EnsemblGRCm39 Ensembl
GRCm38975,231,969 - 75,307,485 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl975,232,020 - 75,305,451 (+)EnsemblGRCm38mm10GRCm38
MGSCv37975,079,821 - 75,153,258 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36975,017,923 - 75,091,360 (+)NCBIMGSCv36mm8
Celera972,390,763 - 72,464,225 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map942.3NCBI
Myo5c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554092,546,909 - 2,612,490 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554092,543,520 - 2,612,867 (+)NCBIChiLan1.0ChiLan1.0
MYO5C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21641,429,040 - 41,530,708 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11545,609,547 - 45,711,119 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01531,133,566 - 31,235,074 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11549,459,741 - 49,549,746 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1549,459,741 - 49,549,752 (-)Ensemblpanpan1.1panPan2
MYO5C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13017,888,422 - 17,972,365 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3017,888,419 - 18,213,061 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3017,817,644 - 17,912,246 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03018,036,561 - 18,131,347 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3018,036,563 - 18,131,405 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13017,955,619 - 18,050,528 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03018,073,656 - 18,168,273 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03018,181,247 - 18,275,989 (-)NCBIUU_Cfam_GSD_1.0
Myo5c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864096,155,020 - 96,246,535 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647114,003,515 - 14,094,587 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647114,003,478 - 14,094,560 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYO5C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1119,407,351 - 119,536,419 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11119,407,298 - 119,536,443 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21132,497,200 - 132,624,942 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MYO5C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12631,095,461 - 31,196,514 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2631,107,036 - 31,196,049 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048110,032,427 - 110,134,967 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myo5c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247318,289,051 - 8,353,346 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247318,288,954 - 8,358,447 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Myo5c
688 total Variants

Predicted Target Of
Summary Value
Count of predictions:103
Count of miRNA genes:87
Interacting mature miRNAs:94
Transcripts:ENSRNOT00000011768
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 57 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat

1 to 10 of 57 rows
AW535147  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2876,049,506 - 76,049,668 (+)MAPPERmRatBN7.2
Rnor_6.0882,231,131 - 82,231,292NCBIRnor6.0
Rnor_5.0881,834,406 - 81,834,567UniSTSRnor5.0
RGSC_v3.4880,102,068 - 80,102,229UniSTSRGSC3.4
Celera875,839,305 - 75,839,466UniSTS
Cytogenetic Map8q24UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 9 49 113 91 90 59 25 59 6 216 95 93 45 60 31



Ensembl Acc Id: ENSRNOT00000011768   ⟹   ENSRNOP00000011768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl875,989,528 - 76,066,483 (+)Ensembl
Rnor_6.0 Ensembl882,171,497 - 82,247,544 (+)Ensembl
RefSeq Acc Id: NM_001108167   ⟹   NP_001101637
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8884,870,043 - 84,946,996 (+)NCBI
mRatBN7.2875,989,528 - 76,066,485 (+)NCBI
RefSeq Acc Id: XM_006243413   ⟹   XP_006243475
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8884,870,032 - 84,946,986 (+)NCBI
mRatBN7.2875,989,515 - 76,066,475 (+)NCBI
Rnor_6.0882,171,296 - 82,248,109 (+)NCBI
Rnor_5.0881,771,484 - 81,851,384 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063265550   ⟹   XP_063121620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8884,895,341 - 84,946,986 (+)NCBI
RefSeq Acc Id: XR_001839460
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8884,870,031 - 84,943,348 (+)NCBI
mRatBN7.2875,989,514 - 76,062,832 (+)NCBI
Rnor_6.0882,171,296 - 82,244,403 (+)NCBI
Sequence:
RefSeq Acc Id: XR_594031
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8884,870,032 - 84,939,289 (+)NCBI
mRatBN7.2875,989,514 - 76,058,775 (+)NCBI
Rnor_6.0882,171,296 - 82,240,349 (+)NCBI
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_001101637 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243475 (Get FASTA)   NCBI Sequence Viewer  
  XP_063121620 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77807 (Get FASTA)   NCBI Sequence Viewer  
  EDL77808 (Get FASTA)   NCBI Sequence Viewer  
  EDL77809 (Get FASTA)   NCBI Sequence Viewer  
  EDL77810 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011768
  ENSRNOP00000011768.7
1 to 9 of 9 rows
RefSeq Acc Id: XP_006243475   ⟸   XM_006243413
- Peptide Label: isoform X1
- UniProtKB: F1M111 (UniProtKB/TrEMBL),   A6I1B7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011768   ⟸   ENSRNOT00000011768
RefSeq Acc Id: NP_001101637   ⟸   NM_001108167
- UniProtKB: A6I1B7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121620   ⟸   XM_063265550
- Peptide Label: isoform X2
Name Modeler Protein Id AA Range Protein Structure
AF-F1M111-F1-model_v2 AlphaFold F1M111 1-1742 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13696134
Promoter ID:EPDNEW_R6651
Type:single initiation site
Name:Myo5c_1
Description:myosin VC
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0882,171,515 - 82,171,575EPDNEW


1 to 38 of 38 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-29824 BioCyc
Ensembl Genes ENSRNOG00000008356 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011768 ENTREZGENE
  ENSRNOT00000011768.8 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.820 UniProtKB/TrEMBL
  1.20.5.190 UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/TrEMBL
  3.30.70.1590 UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/TrEMBL
  6.10.220.10 UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/TrEMBL
InterPro Dilute UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  Myo5c_CBD UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/TrEMBL
  Myosin_N UniProtKB/TrEMBL
  MYSc_Myo5 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene 315820 ENTREZGENE
PANTHER MYOSIN UniProtKB/TrEMBL
  UNCONVENTIONAL MYOSIN-VC UniProtKB/TrEMBL
Pfam DIL UniProtKB/TrEMBL
  Myosin_head UniProtKB/TrEMBL
  PF00612 UniProtKB/TrEMBL
PhenoGen Myo5c PhenoGen
PRINTS MYOSINHEAVY UniProtKB/TrEMBL
PROSITE DILUTE UniProtKB/TrEMBL
  MYOSIN_MOTOR UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  SH3_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008356 RatGTEx
SMART DIL UniProtKB/TrEMBL
  MYSc UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A6I1B7 ENTREZGENE, UniProtKB/TrEMBL
  F1M111 ENTREZGENE, UniProtKB/TrEMBL
1 to 38 of 38 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Myo5c  myosin VC   Myo5c_predicted  myosin VC (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Myo5c_predicted  myosin VC (predicted)      Symbol and Name status set to approved 70820 APPROVED