LENG8-AS1 (LENG8 antisense RNA 1)

Gene: LENG8-AS1 (LENG8 antisense RNA 1) Homo sapiens

Analyze

Symbol:

LENG8-AS1

Name:

LENG8 antisense RNA 1

RGD ID:

9588967

HGNC Page

HGNC:40705

Description:

INTERACTS WITH sodium arsenite

Type:

ncrna (Ensembl: lncRNA)

RefSeq Status:

VALIDATED

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	54,444,816 - 54,449,038 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	54,444,807 - 54,449,430 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	54,955,994 - 54,960,216 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Cytogenetic Map	19	q13.42	NCBI
CHM1_1	19	54,949,835 - 54,954,057 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	57,538,094 - 57,542,316 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

sodium arsenite (EXP)

References

Additional References at PubMed

PMID:16344560

Genomics

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 19q13.41-13.43(chr19:52143873-58445521)x3	copy number gain	See cases [RCV000142008]	Chr19:52143873..58445521 [GRCh38] Chr19:52647126..58956888 [GRCh37] Chr19:57338938..63648700 [NCBI36] Chr19:19q13.41-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3	copy number gain	See cases [RCV000052925]	Chr19:49907832..58557889 [GRCh38] Chr19:50411089..59069256 [GRCh37] Chr19:55102901..63761068 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:51141518-58539965)x3	copy number gain	See cases [RCV000052926]	Chr19:51141518..58539965 [GRCh38] Chr19:51644775..59051332 [GRCh37] Chr19:56336587..63743144 [NCBI36] Chr19:19q13.41-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:50152520-58581203)x3	copy number gain	See cases [RCV000135843]	Chr19:50152520..58581203 [GRCh38] Chr19:50655777..59092570 [GRCh37] Chr19:55347589..63784382 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52955056-58581203)x3	copy number gain	See cases [RCV000134139]	Chr19:52955056..58581203 [GRCh38] Chr19:53458309..59092570 [GRCh37] Chr19:58150121..63784382 [NCBI36] Chr19:19q13.41-13.43	pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52612432-58581203)x3	copy number gain	See cases [RCV000134174]	Chr19:52612432..58581203 [GRCh38] Chr19:53115685..59092570 [GRCh37] Chr19:57807497..63784382 [NCBI36] Chr19:19q13.41-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:50191219-58535818)x3	copy number gain	See cases [RCV000050883]	Chr19:50191219..58535818 [GRCh38] Chr19:50694476..59047185 [GRCh37] Chr19:55386288..63738997 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3	copy number gain	See cases [RCV000052914]	Chr19:47908540..58539965 [GRCh38] Chr19:48411797..59051332 [GRCh37] Chr19:53103609..63743144 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3	copy number gain	See cases [RCV000052915]	Chr19:47929575..58572206 [GRCh38] Chr19:48432832..59083573 [GRCh37] Chr19:53124644..63775385 [NCBI36] Chr19:19q13.33-13.43	pathogenic

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	556
Count of miRNA genes:	445
Interacting mature miRNAs:	472
Transcripts:	ENST00000416022, ENST00000429922, ENST00000448978
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

visual system

adipose tissue

appendage

entire extraembryonic component

pharyngeal arch

High

Medium

488

789

880

417

1646

230

1240

102

1039

981

244

1267

Low

1949

2148

834

539

1499

430

2708

1943

2458

317

421

630

119

960

1519

Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NR_126418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC008746	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC245884	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068259	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU207370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU467002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DB130373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HY002788	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000416022

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	54,445,036 - 54,448,602 (-)	Ensembl

RefSeq Acc Id:

ENST00000429922

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	54,444,813 - 54,449,014 (-)	Ensembl

RefSeq Acc Id:

ENST00000448978

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	54,448,165 - 54,449,045 (-)	Ensembl

RefSeq Acc Id:

ENST00000652740

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	54,444,807 - 54,447,260 (-)	Ensembl

RefSeq Acc Id:

ENST00000686924

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	54,448,076 - 54,449,430 (-)	Ensembl

RefSeq Acc Id:

ENST00000693322

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	54,448,076 - 54,449,430 (-)	Ensembl

RefSeq Acc Id:

NR_126418

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	54,444,816 - 54,449,038 (-)	NCBI
CHM1_1	19	54,949,835 - 54,954,057 (-)	NCBI
T2T-CHM13v2.0	19	57,538,094 - 57,542,316 (-)	NCBI

Sequence:

show sequence

GGCCCCGAGGAGACAAGCGTGGCCGCATTAGCTCTTTCTGCCTCCCACGCAGCCTTATTTTTTT
TATTGTTGTTTTCTTGTTGCTGTTGTTGTTGTTCTCGGAGACGGAGTCTTGCTCTTGCTCTGTC
GTCGCCCACGATAGAGTACAGTGGCGTGATCTCTGCTCACTGCAACCTCCGCCTCCTGGGTTCA
AACAATTCTGCCTCAGCCTCCGGAGTAGCTGGGATTACAGGCGCGCGCCACTATGCCCGGCTAA
TTTTTGTGTTTTTAGTAAAGACGGGGTTTCACCATGTCGGCCAGGCTGTTCTCGAACTCCTGAC
CTCGTGATCCCTCCGTCTCGGCTTCCCAAAGTGCTGGGATTACGGGCGTGAGCCACCGTGCCCG
GCCGCAGCCTTGTTTTGACTGAGTCAGTGGGAGCCATTACTGTTCCTAAATGTAAACTGGCGTG
ACAGGAGTTCCGGGATTGTCCACAGCACGGACTCTGATACAACTATCCAGTCCGCTGCAGGGAC
CGGTCACTGTGTCACAGGTTCTCCAGAGGGCCAGAACTAACAGGATATATGTATATATTGAAAG
GGAGTATATTAGGGAGAACTGGCTGACAGGATCATCAGGCAAAGTCCCACTATAGTCCATCTGC
AAGCTGAGGAAGGAAGAAGCCAGTCACGTCTCAAAGTCCAAAAGCCTCAAAAGTAGGGAAGCCA
ACGGCGCAGCCTTCAGTCTGTGGCGGAAGGCCTAAGAGTCCCCGACAAACCACTGGTGGAAGTT
CAAGAGTCCAAAGGCCAAAGAACCTGGAGTCTAATCTCCAAAGACAGGAAGTATCCAGCACAGG
AGAAAGATGAAAGCCAGAAGACTCAGCAAGCCAGCCCCTCCCACCTTCTGCGCTGACTGG

hide sequence

Promoters

RGD ID:

15097244

Promoter ID:

EPDNEWNC_H2076

Type:

initiation region

Name:

LENG8-AS1_2

Description:

LENG8 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40705]

SO ACC ID:

SO:0000170

Source:

EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.; Paired-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	54,448,616 - 54,448,676	EPDNEWNC

RGD ID:

15097243

Promoter ID:

EPDNEWNC_H2077

Type:

initiation region

Name:

LENG8-AS1_1

Description:

LENG8 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:40705]

SO ACC ID:

SO:0000170

Source:

EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.; Paired-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	54,449,041 - 54,449,101	EPDNEWNC

Additional Information

External Database Links

Database	Acc Id	Source(s)
COSMIC	LENG8-AS1	COSMIC
Ensembl Genes	ENSG00000226696	Ensembl, ENTREZGENE
Ensembl Transcript	ENST00000429922	ENTREZGENE
GTEx	ENSG00000226696	GTEx
HGNC ID	HGNC:40705	ENTREZGENE
Human Proteome Map	LENG8-AS1	Human Proteome Map
NCBI Gene	LENG8-AS1	ENTREZGENE
RNAcentral	URS00007E335F	RNACentral

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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