Itgb6 (integrin subunit beta 6) - Rat Genome Database

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Pathways
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Gene: Itgb6 (integrin subunit beta 6) Chinchilla lanigera
Analyze
Symbol: Itgb6
Name: integrin subunit beta 6
RGD ID: 9024466
Description: ENCODES a protein that exhibits integrin binding (ortholog); molecular function activator activity (ortholog); INVOLVED IN bone development (ortholog); bronchiole development (ortholog); cell adhesion mediated by integrin (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH amelogenesis imperfecta type 1H (ortholog); asthma (ortholog); autistic disorder (ortholog); FOUND IN cell junction (ortholog); cell surface (ortholog); centrosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: integrin beta-6; integrin, beta 6
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544913,448,084 - 13,520,879 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544913,387,013 - 13,520,879 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Itgb6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544913,448,084 - 13,520,879 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544913,387,013 - 13,520,879 (+)NCBIChiLan1.0ChiLan1.0
ITGB6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382160,099,671 - 160,200,272 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2160,099,667 - 160,200,313 (-)EnsemblGRCh38hg38GRCh38
GRCh372160,956,182 - 161,056,783 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362160,666,479 - 160,764,836 (-)NCBINCBI36Build 36hg18NCBI36
Build 342160,783,739 - 160,882,097NCBI
Celera2154,569,718 - 154,668,069 (-)NCBICelera
Cytogenetic Map2q24.2NCBI
HuRef2152,841,567 - 152,939,796 (-)NCBIHuRef
CHM1_12160,964,913 - 161,062,919 (-)NCBICHM1_1
T2T-CHM13v2.02160,557,539 - 160,657,754 (-)NCBIT2T-CHM13v2.0
Itgb6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39260,428,636 - 60,553,005 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl260,428,636 - 60,552,987 (-)EnsemblGRCm39 Ensembl
GRCm38260,598,292 - 60,722,603 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl260,598,292 - 60,722,643 (-)EnsemblGRCm38mm10GRCm38
MGSCv37260,436,349 - 60,560,660 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36260,399,131 - 60,474,500 (-)NCBIMGSCv36mm8
Celera262,295,485 - 62,419,857 (-)NCBICelera
Cytogenetic Map2C1.1- C1.2NCBI
cM Map234.81NCBI
Itgb6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8365,454,964 - 65,579,179 (-)NCBIGRCr8
mRatBN7.2345,046,295 - 45,170,532 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl345,048,044 - 45,121,671 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx348,404,699 - 48,477,782 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0356,988,255 - 57,061,340 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0354,757,778 - 54,831,418 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0346,652,624 - 46,775,362 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl346,652,623 - 46,726,958 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0351,760,871 - 51,883,770 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4342,286,140 - 42,360,793 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1342,182,533 - 42,257,165 (-)NCBI
Celera344,745,206 - 44,817,710 (-)NCBICelera
Cytogenetic Map3q21NCBI
ITGB6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21362,791,601 - 62,961,884 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B62,806,572 - 62,909,714 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B47,386,913 - 47,496,491 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B164,757,913 - 164,867,426 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B164,764,251 - 164,867,426 (-)Ensemblpanpan1.1panPan2
ITGB6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1365,833,206 - 5,962,699 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl365,834,638 - 5,962,633 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha365,972,263 - 6,101,021 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0365,957,679 - 6,086,682 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl365,957,684 - 6,086,586 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1365,974,904 - 6,103,502 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0366,018,081 - 6,146,821 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0366,127,531 - 6,256,234 (-)NCBIUU_Cfam_GSD_1.0
Itgb6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303122,961,499 - 123,089,078 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646918,581,840 - 18,650,123 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646918,581,855 - 18,650,109 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITGB6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1567,041,522 - 67,175,234 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11567,041,516 - 67,175,409 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21574,181,822 - 74,276,814 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ITGB6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11045,506,355 - 45,650,979 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1045,504,987 - 45,595,543 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040153,971,887 - 154,066,448 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Itgb6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247325,403,956 - 5,499,855 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247325,348,589 - 5,499,826 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000004872   ⟹   ENSCLAP00000004782
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544913,448,084 - 13,520,879 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000004873   ⟹   ENSCLAP00000004783
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544913,448,084 - 13,513,547 (+)Ensembl
RefSeq Acc Id: XM_005393349   ⟹   XP_005393406
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544913,387,013 - 13,520,879 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005393354   ⟹   XP_005393411
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544913,387,013 - 13,520,879 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013518789   ⟹   XP_013374243
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544913,448,130 - 13,520,879 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005393406 (Get FASTA)   NCBI Sequence Viewer  
  XP_005393411 (Get FASTA)   NCBI Sequence Viewer  
  XP_013374243 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000004782
  ENSCLAP00000004782.1
  ENSCLAP00000004783
  ENSCLAP00000004783.1
Reference Protein Sequences
RefSeq Acc Id: XP_005393406   ⟸   XM_005393349
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UWP2 (UniProtKB/TrEMBL),   A0A8C2URK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005393411   ⟸   XM_005393354
- Peptide Label: isoform X2
- UniProtKB: A0A8C2URK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013374243   ⟸   XM_013518789
- Peptide Label: isoform X3
- UniProtKB: A0A8C2URK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000004783   ⟸   ENSCLAT00000004873
RefSeq Acc Id: ENSCLAP00000004782   ⟸   ENSCLAT00000004872
Protein Domains
Integrin beta subunit cytoplasmic   Integrin beta subunit tail   Integrin beta subunit VWA   PSI


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003399 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000004872 ENTREZGENE
  ENSCLAT00000004872.1 UniProtKB/TrEMBL
  ENSCLAT00000004873 ENTREZGENE
  ENSCLAT00000004873.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/TrEMBL
  4.10.1240.30 UniProtKB/TrEMBL
  Cytochrome c1, transmembrane anchor, C-terminal UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  ligand-binding face of the semaphorins, domain 2 UniProtKB/TrEMBL
  ntegrin, alpha v. Chain A, domain 3 UniProtKB/TrEMBL
InterPro EGF_extracell UniProtKB/TrEMBL
  I-EGF_1 UniProtKB/TrEMBL
  Integrin_beta_N UniProtKB/TrEMBL
  Integrin_bsu UniProtKB/TrEMBL
  Integrin_bsu_cyt_dom UniProtKB/TrEMBL
  Integrin_bsu_tail UniProtKB/TrEMBL
  Integrin_bsu_tail_dom_sf UniProtKB/TrEMBL
  Integrin_bsu_VWA UniProtKB/TrEMBL
  Integrin_dom_sf UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
NCBI Gene Itgb6 ENTREZGENE
PANTHER PTHR10082 UniProtKB/TrEMBL
  PTHR10082:SF11 UniProtKB/TrEMBL
Pfam EGF_2 UniProtKB/TrEMBL
  I-EGF_1 UniProtKB/TrEMBL
  Integrin_b_cyt UniProtKB/TrEMBL
  Integrin_B_tail UniProtKB/TrEMBL
  Integrin_beta UniProtKB/TrEMBL
  PSI_integrin UniProtKB/TrEMBL
PIRSF Integrin_B UniProtKB/TrEMBL
PRINTS INTEGRINB UniProtKB/TrEMBL
PROSITE INTEGRIN_BETA UniProtKB/TrEMBL
SMART INB UniProtKB/TrEMBL
  Integrin_b_cyt UniProtKB/TrEMBL
  Integrin_B_tail UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  Plexin repeat UniProtKB/TrEMBL
  SSF53300 UniProtKB/TrEMBL
  SSF69179 UniProtKB/TrEMBL
  SSF69687 UniProtKB/TrEMBL
UniProt A0A8C2URK1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UWP2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Itgb6  integrin subunit beta 6    integrin, beta 6  Symbol and/or name change 5135510 APPROVED